SearcharxivSearch

arXiv subjects

Anbang Wang

Publications and source records attributed to Anbang Wang.

At least 19 recordsLinked to original sources

BagShift: Measuring How Patch Selection Changes the Evidence Seen by Whole-Slide MIL

Whole-slide multiple-instance learning (MIL) observes only the patches admitted by its selector. Deployment can alter this selector through compute limits, tissue masking, or regional workflows, even when the patch count is unchanged. We introduce BagShift, a paired protocol that changes the selector for the same case while holding its features and predictor fixed, thereby isolating selector response from case mix. With equal 128-patch budgets, sampling across the tissue or concentrating around one coordinate exposes markedly different evidence: on PANDA, the two views reduce quadratic weighted kappa by 1.57 and 17.96 points, respectively (QWK reported on the $\times100$ scale). On CAMELYON16, lesion annotations withheld from model development show that localized views retain tumor in only 10.0\% of micrometastatic observations, and matched exposure does not consistently recover the loss. The same fixed-count stressor produces a much smaller response on external lung subtyping, although differences in relative coverage make cross-task severity descriptive. When repeated localized observations are available, unioning their patches before one nonlinear MIL pass improves PANDA QWK by 7.87 points over averaging regional predictions. Patch count specifies computation, not observed evidence; deployment evaluations should report both what a selector preserves and how repeated observations are aggregated.

cs.CV

HiPath: Hierarchical Vision-Language Alignment for Structured Pathology Report Prediction

Pathology reports are structured, multi-granular documents encoding diagnostic conclusions, histological grades, and ancillary test results across one or more anatomical sites; yet existing pathology vision-language models (VLMs) reduce this output to a flat label or free-form text. We present HiPath, a lightweight VLM framework built on frozen UNI2 and Qwen3 backbones that treats structured report prediction as its primary training objective. Three trainable modules totalling 15M parameters address complementary aspects of the problem: a Hierarchical Patch Aggregator (HiPA) for multi-image visual encoding, Hierarchical Contrastive Learning (HiCL) for cross-modal alignment via optimal transport, and Slot-based Masked Diagnosis Prediction (Slot-MDP) for structured diagnosis generation. Trained on 749K real-world Chinese pathology cases from three hospitals, HiPath achieves 68.9% strict and 74.7% clinically acceptable accuracy with a 97.3% safety rate, outperforming all baselines under the same frozen backbone. Cross-hospital evaluation confirms generalisation with only a 3.4pp drop in strict accuracy while maintaining 97.1% safety.

cs.CV

SK-Adapter: Skeleton-Based Structural Control for Native 3D Generation

Native 3D generative models have achieved remarkable fidelity and speed, yet they suffer from a critical limitation: inability to prescribe precise structural articulations, where precise structural control within the native 3D space remains underexplored. This paper proposes SK-Adapter, a simple yet efficient and effective framework that unlocks precise skeletal manipulation for native 3D generation. Moving beyond text or image prompts, which can be ambiguous for precise structure, we treat the 3D skeleton as a first-class control signal. SK-Adapter is a lightweight structural adapter network that encodes joint coordinates and topology into learnable tokens, which are injected into the frozen 3D generation backbone via cross-attention. This design allows the model to not only effectively ``attend'' to specific 3D structural constraints but also preserve its original generative priors. To bridge the data gap, we contribute the Objaverse-TMS dataset, a large-scale dataset of 24k text-mesh-skeleton pairs. Extensive experiments confirm that our method achieves robust structural control while preserving the geometry and texture quality of the foundation model, significantly outperforming existing baselines. Furthermore, we extend this capability to local 3D editing, enabling region-specific editing of existing assets with skeletal guidance, which is unattainable by previous methods. Project page: https://sk-adapter.github.io/

cs.CV

ReDiff: Reliability-Guided Diffusion for Trustworthy Ultra-Low-Field to High-Field MRI Synthesis

Low-field to high-field MRI synthesis has emerged as a promising strategy to improve image quality when access to high-field scanners is limited. However, in ultra-low-field settings, the degradation of anatomical detail is spatially heterogeneous: structurally ambiguous regions are more susceptible to unstable high-frequency generation, which may produce anatomically inconsistent textures and boundaries. This issue is particularly problematic when synthesized images are used for downstream quantitative analysis. We therefore study how to make diffusion-based LF-to-HF synthesis more spatially reliable, rather than only sharper on average. To this end, we propose a reliability-guided diffusion framework (ReDiff) with two complementary inference-time mechanisms. First, a reliability-guided sampling strategy attenuates unstable reverse-diffusion updates in regions with weak low-field support. Second, an uncertainty-aware candidate selection scheme aggregates multiple stochastic reconstructions according to spatial consensus and predictive uncertainty. Beyond aggregate image quality, we test whether the uncertainty is itself a usable reliability signal. Experiments on paired 64mT$\rightarrow$3T MRI datasets show that ReDiff attains the lowest LPIPS across three contrasts and two datasets while remaining competitive on PSNR and SSIM, and downstream segmentation analysis indicates better preservation of anatomical structure.

cs.CV

ReasonNavi: Human-Inspired Global Map Reasoning for Zero-Shot Embodied Navigation

Embodied agents often struggle with efficient navigation because they rely primarily on partial egocentric observations, which restrict global foresight and lead to inefficient exploration. In contrast, humans plan using maps: we reason globally first, then act locally. We introduce ReasonNavi, a human-inspired framework that operationalizes this reason-then-act paradigm by coupling Multimodal Large Language Models (MLLMs) with deterministic planners. ReasonNavi converts a top-down map into a discrete reasoning space by room segmentation and candidate target nodes sampling. An MLLM is then queried in a multi-stage process to identify the candidate most consistent with the instruction (object, image, or text goal), effectively leveraging the model's semantic reasoning ability while sidestepping its weakness in continuous coordinate prediction. The selected waypoint is grounded into executable trajectories using a deterministic action planner over an online-built occupancy map, while pretrained object detectors and segmenters ensure robust recognition at the goal. This yields a unified zero-shot navigation framework that requires no MLLM fine-tuning, circumvents the brittleness of RL-based policies and scales naturally with foundation model improvements. Across three navigation tasks, ReasonNavi consistently outperforms prior methods that demand extensive training or heavy scene modeling, offering a scalable, interpretable, and globally grounded solution to embodied navigation. Project page: https://reasonnavi.github.io/

cs.RO

Benchmarking the Impact of Active Space Selection on the VQE Pipeline for Quantum Drug Discovery

Quantum computers promise scalable treatments of electronic structure, yet applying variational quantum eigensolvers (VQE) on realistic drug-like molecules remains constrained by the performance limitations of near-term quantum hardwares. A key strategy for addressing this challenge which effectively leverages current Noisy Intermediate-Scale Quantum (NISQ) hardwares yet remains under-benchmarked is active space selection. We introduce a benchmark that heuristically proposes criteria based on chemically grounded metrics to classify the suitability of a molecule for using quantum computing and then quantifies the impact of active space choices across the VQE pipeline for quantum drug discovery. The suite covers several representative drug-like molecules (e.g., lovastatin, oseltamivir, morphine) and uses chemically motivated active spaces. Our VQE evaluations employ both simulation and quantum processing unit (QPU) execution using unitary coupled-cluster with singles and doubles (UCCSD) and hardware-efficient ansatz (HEA). We adopt a more comprehensive evaluation, including chemistry metrics and architecture-centric metrics. For accuracy, we compare them with classical quantum chemistry methods. This work establishes the first systematic benchmark for active space driven VQE and lays the groundwork for future hardware-algorithm co-design studies in quantum drug discovery.

physics.chem-ph

GPU Kernel Optimization Beyond Full Builds: An LLM Framework with Minimal Executable Programs

In high-performance computing, hotspot GPU kernels are primary bottlenecks, and expert manual tuning is costly and hard to port. Large language model methods often assume kernels can be compiled and executed cheaply, which fails in large applications where full builds and runs are expensive. We present an end-to-end LLM framework with performance feedback that optimizes kernels without building the full application. From independently extracted hotspot kernels, it automatically completes code into a Minimal Executable Program (MEP), then performs multi-round iterative optimization and evaluation outside the full application. The framework integrates Automatic Error Repair and Performance Pattern Inheritance to fix faults, preserve correctness, reuse effective tiling/memory/synchronization strategies, and reduce search cost. Optimized variants are reintegrated into the original application for validation. We evaluate on NVIDIA GPUs and the Haiguang Deep Computing Unit (DCU) platform (AMD-licensed architecture) using PolyBench, the AMD APP SDK, and hotspot kernels from large-scale supercomputing applications. The method achieves average speedups of 5.05x (PolyBench on NVIDIA), 7.77x (PolyBench on DCU), 1.77x (AMD APP SDK), and 1.25x on three hotspot kernels, surpassing direct LLM optimization. The approach requires no full-source dependencies, offers cross-platform portability, and enables practical, low-cost GPU kernel optimization.

cs.DC

MedSapiens: Taking a Pose to Rethink Medical Imaging Landmark Detection

This paper does not introduce a novel architecture; instead, it revisits a fundamental yet overlooked baseline: adapting human-centric foundation models for anatomical landmark detection in medical imaging. While landmark detection has traditionally relied on domain-specific models, the emergence of large-scale pre-trained vision models presents new opportunities. In this study, we investigate the adaptation of Sapiens, a human-centric foundation model designed for pose estimation, to medical imaging through multi-dataset pretraining, establishing a new state of the art across multiple datasets. Our proposed model, MedSapiens, demonstrates that human-centric foundation models, inherently optimized for spatial pose localization, provide strong priors for anatomical landmark detection, yet this potential has remained largely untapped. We benchmark MedSapiens against existing state-of-the-art models, achieving up to 5.26% improvement over generalist models and up to 21.81% improvement over specialist models in the average success detection rate (SDR). To further assess MedSapiens adaptability to novel downstream tasks with few annotations, we evaluate its performance in limited-data settings, achieving 2.69% improvement over the few-shot state of the art in SDR. Code and model weights are available at https://github.com/xmed-lab/MedSapiens .

cs.CV

Achieving High-Quality Portfolio Optimization with the Variational Quantum Eigensolver

Portfolio optimization lies at the core of quantitative finance and aims to determine how assets should be allocated to balance expected returns against risk. It can be formulated as a Quadratic Unconstrained Binary Optimization (QUBO) problem, which is NP-hard. Quantum computing offers the potential to solve such problems more efficiently than classical methods. In this work, we employ the Variational Quantum Eigensolver (VQE) to address the portfolio optimization problem. To increase the likelihood of converging to high-quality solutions, we propose using the Weighted Conditional Value-at-Risk (WCVaR) as the cost function and the Covariance Matrix Adaptation Evolution Strategy (CMA-ES) as the optimizer. Our experiments are conducted using both classical simulations and quantum hardware on the Wuyue QuantumAI platform. Together, these results demonstrate that the combination of WCVaR and CMA-ES improves the performance of VQE for portfolio optimization and provides a practical route for applications on NISQ devices.

quant-ph

Geometric-Guided Few-Shot Dental Landmark Detection with Human-Centric Foundation Model

Accurate detection of anatomic landmarks is essential for assessing alveolar bone and root conditions, thereby optimizing clinical outcomes in orthodontics, periodontics, and implant dentistry. Manual annotation of landmarks on cone-beam computed tomography (CBCT) by dentists is time-consuming, labor-intensive, and subject to inter-observer variability. Deep learning-based automated methods present a promising approach to streamline this process efficiently. However, the scarcity of training data and the high cost of expert annotations hinder the adoption of conventional deep learning techniques. To overcome these challenges, we introduce GeoSapiens, a novel few-shot learning framework designed for robust dental landmark detection using limited annotated CBCT of anterior teeth. Our GeoSapiens framework comprises two key components: (1) a robust baseline adapted from Sapiens, a foundational model that has achieved state-of-the-art performance in human-centric vision tasks, and (2) a novel geometric loss function that improves the model's capacity to capture critical geometric relationships among anatomical structures. Experiments conducted on our collected dataset of anterior teeth landmarks revealed that GeoSapiens surpassed existing landmark detection methods, outperforming the leading approach by an 8.18% higher success detection rate at a strict 0.5 mm threshold-a standard widely recognized in dental diagnostics. Code is available at: https://github.com/xmed-lab/GeoSapiens.

cs.CV

Surrogate Modeling via Factorization Machine and Ising Model with Enhanced Higher-Order Interaction Learning

Recently, a surrogate model was proposed that employs a factorization machine to approximate the underlying input-output mapping of the original system, with quantum annealing used to optimize the resulting surrogate function. Inspired by this approach, we propose an enhanced surrogate model that incorporates additional slack variables into both the factorization machine and its associated Ising representation thereby unifying what was by design a two-step process into a single, integrated step. During the training phase, the slack variables are iteratively updated, enabling the model to account for higher-order feature interactions. We apply the proposed method to the task of predicting drug combination effects. Experimental results indicate that the introduction of slack variables leads to a notable improvement of performance. Our algorithm offers a promising approach for building efficient surrogate models that exploit potential quantum advantages.

cs.LG

Experimental realization of the bucket-brigade quantum random access memory

Quantum random access memory (QRAM) enables efficient classical data access for quantum computers -- a prerequisite for many quantum algorithms to achieve quantum speedup. Despite various proposals, the experimental realization of QRAM remains largely unexplored. Here, we experimentally investigate the circuit-based bucket-brigade QRAM with a superconducting quantum processor. To facilitate the experimental implementation, we introduce a hardware-efficient gate decomposition scheme for quantum routers, which effectively reduces the depth of the QRAM circuit by more than 30% compared to the conventional controlled-SWAP-based implementation. We further propose an error mitigation method to boost the QRAM query fidelity. With these techniques, we are able to experimentally implement the QRAM architectures with two and three layers, achieving query fidelities up to 0.800 $\pm$ 0.026 and 0.604$\pm$0.005, respectively. Additionally, we study the error propagation mechanism and the scalability of our QRAM implementation, providing experimental evidence for the noise resilience nature of the bucket-brigade QRAM architecture. Our results highlight the potential of superconducting quantum processors for realizing a scalable QRAM architecture.

quant-ph

ReverseNER: A Self-Generated Example-Driven Framework for Zero-Shot Named Entity Recognition with Large Language Models

This paper presents ReverseNER, a method aimed at overcoming the limitation of large language models (LLMs) in zero-shot named entity recognition (NER) tasks, arising from their reliance on pre-provided demonstrations. ReverseNER tackles this challenge by constructing a reliable example library composed of dozens of entity-labeled sentences, generated through the reverse process of NER. Specifically, while conventional NER methods label entities in a sentence, ReverseNER features reversing the process by using an LLM to generate entities from their definitions and subsequently expand them into full sentences. During the entity expansion process, the LLM is guided to generate sentences by replicating the structures of a set of specific \textsl{feature sentences}, extracted from the task sentences by clustering. This expansion process produces dozens of entity-labeled task-relevant sentences. After constructing the example library, the method selects several semantically similar entity-labeled examples for each task sentence as references to facilitate the LLM's entity recognition. We also propose an entity-level self-consistency scoring mechanism to improve NER performance with LLMs. Experiments show that ReverseNER significantly outperforms other zero-shot NER methods with LLMs, marking a notable improvement in NER for domains without labeled data, while declining computational resource consumption.

cs.CL

Measurement-efficient quantum Krylov subspace diagonalisation

The Krylov subspace methods, being one category of the most important classical numerical methods for linear algebra problems, can be much more powerful when generalised to quantum computing. However, quantum Krylov subspace algorithms are prone to errors due to inevitable statistical fluctuations in quantum measurements. To address this problem, we develop a general theoretical framework to analyse the statistical error and measurement cost. Based on the framework, we propose a quantum algorithm to construct the Hamiltonian-power Krylov subspace that can minimise the measurement cost. In our algorithm, the product of power and Gaussian functions of the Hamiltonian is expressed as an integral of the real-time evolution, such that it can be evaluated on a quantum computer. We compare our algorithm with other established quantum Krylov subspace algorithms in solving two prominent examples. To achieve an error comparable to that of the classical Lanczos algorithm at the same subspace dimension, our algorithm typically requires orders of magnitude fewer measurements than others. Such an improvement can be attributed to the reduced cost of composing projectors onto the ground state. These results show that our algorithm is exceptionally robust to statistical fluctuations and promising for practical applications.

quant-ph

Maximising Quantum-Computing Expressive Power through Randomised Circuits

In the noisy intermediate-scale quantum era, variational quantum algorithms (VQAs) have emerged as a promising avenue to obtain quantum advantage. However, the success of VQAs depends on the expressive power of parameterised quantum circuits, which is constrained by the limited gate number and the presence of barren plateaus. In this work, we propose and numerically demonstrate a novel approach for VQAs, utilizing randomised quantum circuits to generate the variational wavefunction. We parameterize the distribution function of these random circuits using artificial neural networks and optimize it to find the solution. This random-circuit approach presents a trade-off between the expressive power of the variational wavefunction and time cost, in terms of the sampling cost of quantum circuits. Given a fixed gate number, we can systematically increase the expressive power by extending the quantum-computing time. With a sufficiently large permissible time cost, the variational wavefunction can approximate any quantum state with arbitrary accuracy. Furthermore, we establish explicit relationships between expressive power, time cost, and gate number for variational quantum eigensolvers. These results highlight the promising potential of the random-circuit approach in achieving a high expressive power in quantum computing.

quant-ph

Physical-layer key distribution using synchronous complex dynamics of DBR semiconductor lasers

Common-signal-induced synchronization of semiconductor lasers with optical feedback inspired a promising physical key distribution with information-theoretic security and potential in high rate. A significant challenge is the requirement to shorten the synchronization recovery time for increasing key rate without sacrificing operation parameter space for security. Here, open-loop synchronization of wavelength-tunable multi-section distributed Bragg reflector (DBR) lasers is proposed as a solution for physical-layer key distribution. Experiments show that the synchronization is sensitive to two operation parameters, i.e., currents of grating section and phase section. Furthermore, fast wavelength-shift keying synchronization can be achieved by direct modulation on one of the two currents. The synchronization recovery time is shortened by one order of magnitude compared to close-loop synchronization. An experimental implementation is demonstrated with a final key rate of 5.98 Mbit/s over 160 km optical fiber distance. It is thus believed that fast-tunable multi-section semiconductor lasers opens a new avenue of high-rate physical-layer key distribution using laser synchronization.

physics.optics

Error-mitigated deep-circuit quantum simulation of open systems: steady state and relaxation rate problems

Deep-circuit quantum computation, like Shor's algorithm, is undermined by error accumulation, and near-future quantum techniques are far from adequate for full-fledged quantum error correction. Instead of resorting to shallow-circuit quantum algorithms, recent theoretical research suggests that digital quantum simulation (DQS) of closed quantum systems are robust against the accumulation of Trotter errors, as long as local observables are concerned. In this paper, we investigate digital quantum simulation of open quantum systems. First, we prove that the deviation in the steady state obtained from digital quantum simulation depends only on the error in a single Trotter step, which indicates that error accumulation may not be disastrous. By numerical simulation of the quantum circuits for the DQS of the dissipative XYZ model, we then show that the correct results can be recovered by quantum error mitigation as long as the error rate in the DQS is below a sharp threshold. We explain this threshold behavior by the existence of a dissipation-driven quantum phase transition. Finally, we propose a new error-mitigation technique based on the scaling behavior in the vicinity of the critical point of a quantum phase transition. Our results expand the territory of near-future available quantum algorithms and stimulate further theoretical and experimental efforts in practical quantum applications.

quant-ph

0.75 Gbit/s high-speed classical key distribution with mode-shift keying chaos synchronization of Fabry-Perot lasers

High-speed physical key distribution is diligently pursued for secure communication. In this paper, we propose and experimentally demonstrate a scheme of high-speed key distribution using mode-shift keying chaos synchronization between two multi-longitudinal-mode Fabry-Perot lasers commonly driven by a super-luminescent diode. Legitimate users dynamically select one of the longitudinal modes according to private control codes to achieve mode-shift keying chaos synchronization. The two remote chaotic light waveforms are quantized to generate two raw random bit streams, and then those bits corresponding to chaos synchronization are sifted as shared keys by comparing the control codes. In this method, the transition time, i.e., the chaos synchronization recovery time is determined by the rising time of the control codes rather than the laser transition response time, so the key distribution rate is improved greatly. Our experiment achieved 0.75-Gbit/s key distribution rate with a bit error rate of 3.8*10-3 over 160-km fiber transmission with dispersion compensation. The entropy rate of the laser chaos is evaluated as 16 Gbit/s, which determines the ultimate final key rate together with key generation ratio. It is therefore believed that the method pays a way for Gbit/s physical key distribution.

physics.optics