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Andrés F. Barrientos

Publications and source records attributed to Andrés F. Barrientos.

18 recordsLinked to original sources

Bayesian Analysis Using a Constrained Mixture of Normal-Inverse-Gamma Models

Gaussian mixtures of regressions are commonly implemented via a Gibbs sampler. This Markov chain Monte Carlo (MCMC) algorithm can be computationally burdensome because of the need to update discrete-valued latent component allocation parameters whose dimension increases as the sample size increases. In this article, we propose applying the method of composition to a Gaussian finite mixture model with a Normal-Inverse-Gamma (NIG) prior which allows one to write the posterior distribution as the product of conditional distributions. Namely, the conditional distribution of parameters given the data and mixture labels, times the marginal posterior of the mixture labels. The conditional distribution of parameters given the data and mixture labels, can be sampled from directly, instead of using MCMC. The expression of the marginal posterior of the mixture labels is known up to a proportionality constant and we adapt existing approaches in Bayesian selective inference to constrain the space of component labels to those arising from preliminary estimators, which alleviates a commonly encountered bottleneck. In simulation studies, we consider several settings and compare several versions of our constrained mixture of NIG models to two different MCMC-based strategies and demonstrate their use on natality data from the CDC.

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Uncertainty Quantification in Bayesian Clustering

Bayesian clustering methods have the widely touted advantage of providing a probabilistic characterization of uncertainty in clustering through the posterior distribution. An amazing variety of priors and likelihoods have been proposed for clustering in a broad array of settings. There is also a rich literature on Markov chain Monte Carlo (MCMC) algorithms for sampling from posterior clustering distributions. However, there is relatively little work on summarizing the posterior uncertainty. The complexity of the partition space corresponding to different clusterings makes this problem challenging. We propose a post-processing procedure for any Bayesian clustering model with posterior samples that generates a credible set that is easy to use, fast to compute, and intuitive to interpret. We also provide new measures of clustering uncertainty and show how to compute cluster-specific parameter estimates and credible regions that accumulate a desired posterior probability without having to condition on a partition estimate or employ label-switching techniques. We illustrate our procedure through several applications.

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Bayesian nonparametric modeling of mixed-type bounded data

We propose a Bayesian nonparametric model for mixed-type bounded data, where some variables are compositional and others are interval-bounded. Compositional variables are non-negative and sum to a given constant, such as the proportion of time an individual spends on different activities during the day or the fraction of different types of nutrients in a person's diet. Interval-bounded variables, on the other hand, are real numbers constrained by both a lower and an upper bound. Our approach relies on a novel class of random multivariate Bernstein polynomials, which induce a Dirichlet process mixture model of products of Dirichlet and beta densities. We study the theoretical properties of the model, including its topological support and posterior consistency. The model can be used for density and conditional density estimation, where both the response and predictors take values in the simplex space and/or hypercube. We illustrate the model's behavior through the analysis of simulated data and data from the 2005-2006 cycle of the U.S. National Health and Nutrition Examination Survey.

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Profile Monitoring via Eigenvector Perturbation

In Statistical Process Control, control charts are often used to detect undesirable behavior of sequentially observed quality characteristics. Designing a control chart with desirably low False Alarm Rate (FAR) and detection delay ($ARL_1$) is an important challenge especially when the sampling rate is high and the control chart has an In-Control Average Run Length, called $ARL_0$, of 200 or more, as commonly found in practice. Unfortunately, arbitrary reduction of the FAR typically increases the $ARL_1$. Motivated by eigenvector perturbation theory, we propose the Eigenvector Perturbation Control Chart for computationally fast nonparametric profile monitoring. Our simulation studies show that it outperforms the competition and achieves both $ARL_1 \approx 1$ and $ARL_0 > 10^6$.

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Differentially Private Methods for Compositional Data

Confidential data, such as electronic health records, activity data from wearable devices, and geolocation data, are becoming increasingly prevalent. Differential privacy provides a framework to conduct statistical analyses while mitigating the risk of leaking private information. Compositional data, which consist of vectors with positive components that add up to a constant, have received little attention in the differential privacy literature. This article proposes differentially private approaches for analyzing compositional data using the Dirichlet distribution. We explore several methods, including Bayesian and bootstrap procedures. For the Bayesian methods, we consider posterior inference techniques based on Markov Chain Monte Carlo, Approximate Bayesian Computation, and asymptotic approximations. We conduct an extensive simulation study to compare these approaches and make evidence-based recommendations. Finally, we apply the methodology to a data set from the American Time Use Survey.

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Nonparametric Multivariate Profile Monitoring Via Tree Ensembles

Monitoring random profiles over time is used to assess whether the system of interest, generating the profiles, is operating under desired conditions at any time-point. In practice, accurate detection of a change-point within a sequence of responses that exhibit a functional relationship with multiple explanatory variables is an important goal for effectively monitoring such profiles. We present a nonparametric method utilizing ensembles of regression trees and random forests to model the functional relationship along with associated Kolmogorov-Smirnov statistic to monitor profile behavior. Through a simulation study considering multiple factors, we demonstrate that our method offers strong performance and competitive detection capability when compared to existing methods.

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Mixture representations and Bayesian nonparametric inference for likelihood ratio ordered distributions

In this article, we introduce mixture representations for likelihood ratio ordered distributions. Essentially, the ratio of two probability densities, or mass functions, is monotone if and only if one can be expressed as a mixture of one-sided truncations of the other. To illustrate the practical value of the mixture representations, we address the problem of density estimation for likelihood ratio ordered distributions. In particular, we propose a nonparametric Bayesian solution which takes advantage of the mixture representations. The prior distribution is constructed from Dirichlet process mixtures and has large support on the space of pairs of densities satisfying the monotone ratio constraint. Posterior consistency holds under reasonable conditions on the prior specification and the true unknown densities. To our knowledge, this is the first posterior consistency result in the literature on order constrained inference. With a simple modification to the prior distribution, we can test the equality of two distributions against the alternative of likelihood ratio ordering. We develop a Markov chain Monte Carlo algorithm for posterior inference and demonstrate the method in a biomedical application.

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Differentially private methods for managing model uncertainty in linear regression models

In this work, we propose differentially private methods for hypothesis testing, model averaging, and model selection for normal linear models. We consider Bayesian methods based on mixtures of $g$-priors and non-Bayesian methods based on likelihood-ratio statistics and information criteria. The procedures are asymptotically consistent and straightforward to implement with existing software. We focus on practical issues such as adjusting critical values so that hypothesis tests have adequate type I error rates and quantifying the uncertainty introduced by the privacy-ensuring mechanisms.

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Incompatibilities Between Current Practices in Statistical Data Analysis and Differential Privacy

The authors discuss their experience applying differential privacy with a complex data set with the goal of enabling standard approaches to statistical data analysis. They highlight lessons learned and roadblocks encountered, distilling them into incompatibilities between current practices in statistical data analysis and differential privacy that go beyond issues which can be solved with a noisy measurements file. The authors discuss how overcoming these incompatibilities require compromise and a change in either our approach to statistical data analysis or differential privacy that should be addressed head-on.

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A Feasibility Study of Differentially Private Summary Statistics and Regression Analyses with Evaluations on Administrative and Survey Data

Federal administrative data, such as tax data, are invaluable for research, but because of privacy concerns, access to these data is typically limited to select agencies and a few individuals. An alternative to sharing microlevel data is to allow individuals to query statistics without directly accessing the confidential data. This paper studies the feasibility of using differentially private (DP) methods to make certain queries while preserving privacy. We also include new methodological adaptations to existing DP regression methods for using new data types and returning standard error estimates. We define feasibility as the impact of DP methods on analyses for making public policy decisions and the queries accuracy according to several utility metrics. We evaluate the methods using Internal Revenue Service data and public-use Current Population Survey data and identify how specific data features might challenge some of these methods. Our findings show that DP methods are feasible for simple, univariate statistics but struggle to produce accurate regression estimates and confidence intervals. To the best of our knowledge, this is the first comprehensive statistical study of DP regression methodology on real, complex datasets, and the findings have significant implications for the direction of a growing research field and public policy.

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Differentially Private Hypothesis Testing with the Subsampled and Aggregated Randomized Response Mechanism

Randomized response is one of the oldest and most well-known methods for analyzing confidential data. However, its utility for differentially private hypothesis testing is limited because it cannot achieve high privacy levels and low type I error rates simultaneously. In this article, we show how to overcome this issue with the subsample and aggregate technique. The result is a general-purpose method that can be used for both frequentist and Bayesian testing. {{We illustrate the performance of our proposal in three scenarios: goodness-of-fit testing for linear regression models, nonparametric testing of a location parameter with the Wilcoxon test, and the nonparametric Kruskal-Wallis test.

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Nonparametric Bayesian Approach to Treatment Ranking in Network Meta-Analysis with Application to Comparisons of Antidepressants

Network meta-analysis is a powerful tool to synthesize evidence from independent studies and compare multiple treatments simultaneously. A critical task of performing a network meta-analysis is to offer ranks of all available treatment options for a specific disease outcome. Frequently, the estimated treatment rankings are accompanied by a large amount of uncertainty, suffer from multiplicity issues, and rarely permit ties. These issues make interpreting rankings problematic as they are often treated as absolute metrics. To address these shortcomings, we formulate a ranking strategy that adapts to scenarios with high order uncertainty by producing more conservative results. This improves the interpretability while simultaneously accounting for multiple comparisons. To admit ties between treatment effects, we also develop a Bayesian Nonparametric approach for network meta-analysis. The approach capitalizes on the induced clustering mechanism of Bayesian Nonparametric methods producing a positive probability that two treatment effects are equal. We demonstrate the utility of the procedure through numerical experiments and a network meta-analysis designed to study antidepressant treatments.

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A Latent Class Modeling Approach for Generating Synthetic Data and Making Posterior Inferences from Differentially Private Counts

Several algorithms exist for creating differentially private counts from contingency tables, such as two-way or three-way marginal counts. The resulting noisy counts generally do not correspond to a coherent contingency table, so that some post-processing step is needed if one wants the released counts to correspond to a coherent contingency table. We present a latent class modeling approach for post-processing differentially private marginal counts that can be used (i) to create differentially private synthetic data from the set of marginal counts, and (ii) to enable posterior inferences about the confidential counts. We illustrate the approach using a subset of the 2016 American Community Survey Public Use Microdata Sets and the 2004 National Long Term Care Survey.

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Dependent Bayesian nonparametric modeling of compositional data using random Bernstein polynomials

We discuss Bayesian nonparametric procedures for the regression analysis of compositional responses, that is, data supported on a multivariate simplex. The procedures are based on a modified class of multivariate Bernstein polynomials and on the use of dependent stick-breaking processes. A general model and two simplified versions of the general model are discussed. Appealing theoretical properties such as continuity, association structure, support, and consistency of the posterior distribution are established. Additionally, we exploit the use of spike-and-slab priors for choosing the version of the model that best adapts to the complexity of the underlying true data-generating distribution. The performance of the proposed model is illustrated in a simulation study and in an application to solid waste data from Colombia.

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Bayesian Bootstraps for Massive Data

In this article, we present data-subsetting algorithms that allow for the approximate and scalable implementation of the Bayesian bootstrap. They are analogous to two existing algorithms in the frequentist literature: the bag of little bootstraps (Kleiner et al., 2014) and the subsampled double bootstrap (SDB; Sengupta et al., 2016). Our algorithms have appealing theoretical and computational properties that are comparable to those of their frequentist counterparts. Additionally, we provide a strategy for performing lossless inference for a class of functionals of the Bayesian bootstrap, and briefly introduce extensions to the Dirichlet Process.

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Multiple Imputation of Missing Values in Household Data with Structural Zeros

We present an approach for imputation of missing items in multivariate categorical data nested within households. The approach relies on a latent class model that (i) allows for household level and individual level variables, (ii) ensures that impossible household configurations have zero probability in the model, and (iii) can preserve multivariate distributions both within households and across households. We present a Gibbs sampler for estimating the model and generating imputations. We also describe strategies for improving the computational efficiency of the model estimation. We illustrate the performance of the approach with data that mimic the variables collected in typical population censuses.

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Providing Access to Confidential Research Data Through Synthesis and Verification: An Application to Data on Employees of the U.S. Federal Government

Data stewards seeking to provide access to large-scale social science data face a difficult challenge. They have to share data in ways that protect privacy and confidentiality, are informative for many analyses and purposes, and are relatively straightforward to use by data analysts. One approach suggested in the literature is that data stewards generate and release synthetic data, i.e., data simulated from statistical models, while also providing users access to a verification server that allows them to assess the quality of inferences from the synthetic data. We present an application of the synthetic data plus verification server approach to longitudinal data on employees of the U.S. federal government. As part of the application, we present a novel model for generating synthetic career trajectories, as well as strategies for generating high dimensional, longitudinal synthetic datasets. We also present novel verification algorithms for regression coefficients that satisfy differential privacy. We illustrate the integrated use of synthetic data plus verification via analysis of differentials in pay by race. The integrated system performs as intended, allowing users to explore the synthetic data for potential pay differentials and learn through verifications which findings in the synthetic data hold up and which do not. The analysis on the confidential data reveals pay differentials across races not documented in published studies.

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Differentially private significance tests for regression coefficients

Many data producers seek to provide users access to confidential data without unduly compromising data subjects' privacy and confidentiality. One general strategy is to require users to do analyses without seeing the confidential data; for example, analysts only get access to synthetic data or query systems that provide disclosure-protected outputs of statistical models. With synthetic data or redacted outputs, the analyst never really knows how much to trust the resulting findings. In particular, if the user did the same analysis on the confidential data, would regression coefficients of interest be statistically significant or not? We present algorithms for assessing this question that satisfy differential privacy. We describe conditions under which the algorithms should give accurate answers about statistical significance. We illustrate the properties of the proposed methods using artificial and genuine data.

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