arXiv subjects

Andrea Signori

Publications and source records attributed to Andrea Signori.

At least 37 records · Page 2Linked to original sources

arXiv2023

On a Cahn-Hilliard system with source term and thermal memory

A nonisothermal phase field system of Cahn-Hilliard type is introduced and analyzed mathematically. The system constitutes an extension of the classical Caginalp model for nonisothermal phase transitions with a conserved order parameter. It couples a Cahn-Hilliard type equation with source term for the order parameter with the universal balance law of internal energy. In place of the standard Fourier form, the constitutive law of the heat flux is assumed in the form given by the theory developed by Green and Naghdi, which accounts for a possible thermal memory of the evolution. This has the consequence that the balance law of internal energy becomes a second-order in time equation for the thermal displacement or freezing index, that is, a primitive with respect to time of the temperature. Another particular feature of our system is the presence of the source term in the equation for the order parameter, which entails additional mathematical difficulties because the mass conservation of the order parameter is lost. We provide several mathematical results under general assumptions on the source term and the double-well nonlinearity governing the evolution: existence and continuous dependence results are shown for weak and strong solutions to the corresponding initial-boundary value problem.

math.AP↗

arXiv2023

Gauge invariant spectral analysis of quark hadronization dynamics

We study the Dirac decomposition of the gauge invariant quark propagator, whose imaginary part describes the hadronization of a quark as this interacts with the vacuum, and relate each of its coefficients to a specific sum rule for the chiral-odd and chiral-even quark spectral functions. Working at first in light-like axial gauge, we obtain a new sum rule for the spectral function associated to the gauge fixing vector, and show that its second moment is in fact equal to zero. Then, we demonstrate that the first moment of the chiral-odd quark spectral function is equal in any gauge to the so-called inclusive jet mass, which is related to the mass of the particles produced in the hadronization of a quark. Finally, we present a gauge-dependent formula that connects the second moment of the chiral-even quark spectral function to invariant mass generation and final state rescattering in the hadronization of a quark.

hep-ph↗

arXiv2023

Analysis of a multi-species Cahn-Hilliard-Keller-Segel tumor growth model with chemotaxis and angiogenesis

We introduce a multi-species diffuse interface model for tumor growth, characterized by its incorporation of essential features related to chemotaxis, angiogenesis and proliferation mechanisms. We establish the weak well-posedness of the system within an appropriate variational framework, accommodating various choices for the nonlinear potentials. One of the primary novelties of the work lies in the rigorous establishment of the existence of a weak solution through the introduction of delicate approximation schemes. To our knowledge, this represents a novel advancement for both the intricate Cahn-Hilliard-Keller-Segel system and the Keller-Segel subsystem with source terms. Moreover, when specific conditions are met, such as having more regular initial data, a smallness condition on the chemotactic constant with respect to the magnitude of initial conditions and potentially focusing solely on the two-dimensional case, we provide regularity results for the weak solutions. Finally, we derive a continuous dependence estimate, which, in turn, leads to the uniqueness of the smoothed solution as a natural consequence.

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arXiv2023

Nutrient control for a viscous Cahn-Hilliard-Keller-Segel model

In this paper, we address a distributed control problem for a system of partial differential equations describing the evolution of a tumor that takes the biological mechanism of chemotaxis into account. The system describing the evolution is obtained as a nontrivial combination of a Cahn-Hilliard type system accounting for the segregation between tumor cells and healthy cells, with a Keller-Segel type equation accounting for the evolution of a nutrient species and modeling the chemotaxis phenomenon. First, we develop a robust mathematical background that allows us to analyze an associated optimal control problem. This analysis forced us to select a source term of logistic type in the nutrient equation and to restrict the analysis to the case of two space dimensions. Then, the existence of an optimal control and first-order necessary conditions for optimality are established.

math.OC↗

arXiv2023

Well-posedness and optimal control for a viscous Cahn-Hilliard-Oono system with dynamic boundary conditions

In this paper we consider a nonlinear system of PDEs coupling the viscous Cahn-Hilliard-Oono equation with dynamic boundary conditions enjoying a similar structure on the boundary. After proving well-posedness of the corresponding initial boundary value problem, we study an associated optimal control problem related to a tracking-type cost functional, proving first-order necessary conditions of optimality. The controls enter the system in the form of a distributed and a boundary source. We can account for general potentials in the bulk and in the boundary part under the common assumption that the boundary potential is dominant with respect to the bulk one. For example, the regular quartic potential as well as the logarithmic potential can be considered in our analysis.

math.AP↗

arXiv2023

Hadronization dynamics from the spectral representation of the gauge invariant quark propagator

Using the spectral representation of the quark propagator we study the Dirac decomposition of the gauge invariant quark propagator, whose imaginary part describes the hadronization of a quark as this interacts with the vacuum. We then demonstrate the formal gauge invariance of the so-called jet mass, that is of the coefficient of the chiral-odd part of the gauge invariant propagator, that can be expressed in any gauge as the first moment of the chiral-odd quark spectral function. This is therefore revealed to be a \textit{bona fide} QCD observable encoding aspects of the dynamical mass generation in the QCD vacuum, and is furthermore experimentally measurable in specific twist-3 longitudinal-transverse asymmetries in DIS and in semi-inclusive electron-positron collisions. In light-like axial gauges, we also obtain a new sum rule for the spectral function associated with the gauge fixing vector. We finally present a gauge-dependent formula that connects the second moment of the chiral-even coefficient of the quark spectral function to invariant mass generation and final state rescattering in the hadronization of a quark. Finding twist-4 experimental observables sensitive to this quantity is left for future work.

hep-ph↗

arXiv2023

Second-order analysis of an optimal control problem in a phase field tumor growth model with singular potentials and chemotaxis

This paper concerns a distributed optimal control problem for a tumor growth model of Cahn-Hilliard type including chemotaxis with possibly singular potentials, where the control and state variables are nonlinearly coupled. First, we discuss the weak well-posedness of the system under very general assumptions for the potentials, which may be singular and nonsmooth. Then, we establish the strong well-posedness of the system in a reduced setting, which however admits the logarithmic potential: this analysis will lay the foundation for the study of the corresponding optimal control problem. Concerning the optimization problem, we address the existence of minimizers and establish both first-order necessary and second-order sufficient conditions for optimality. The mathematically challenging second-order analysis is completely performed here, after showing that the solution mapping is twice continuously differentiable between suitable Banach spaces via the implicit function theorem. Then, we completely identify the second-order Fréchet derivative of the control-to-state operator and carry out a thorough and detailed investigation about the related properties.

math.OC↗

arXiv2023

Optimal temperature distribution for a nonisothermal Cahn-Hilliard system in two dimensions with source term and double obstacle potential

In this note, we study the optimal control of a nonisothermal phase field system of Cahn-Hilliard type that constitutes an extension of the classical Caginalp model for nonisothermal phase transitions with a conserved order parameter. It couples a Cahn-Hilliard type equation with source term for the order parameter with the universal balance law of internal energy. In place of the standard Fourier form, the constitutive law of the heat flux is assumed in the form given by the theory developed by Green and Naghdi, which accounts for a possible thermal memory of the evolution. This has the consequence that the balance law of internal energy becomes a second-order in time equation for the thermal displacement or freezing index, that is, a primitive with respect to time of the temperature. Another particular feature of our system is the presence of the source term in the equation for the order parameter, which entails further mathematical difficulties because the mass conservation of the order parameter is no longer satisfied. We study the case that the double-well potential driving the evolution of the phase transition is given by the nondifferentiable double obstacle potential, thereby complementing recent results obtained for the differentiable cases of regular and logarithmic potentials. We derive first-order necessary optimality conditions for the control problem. The analysis is carried out by employing the so-called deep quench approximation in which the nondifferentiable double obstacle potential is approximated by a family of logarithmic potentials for which meaningful first-order necessary optimality conditions are available. Since the results for the logarithmic potentials crucially depend on the validity of the so-called strict separation property which is only available in the spatially two-dimensional situation, our whole analysis is restricted to the two-dimensional case.

math.OC↗

arXiv2023

Optimal temperature distribution for a nonisothermal Cahn-Hilliard system with source term

In this note, we study the optimal control of a nonisothermal phase field system of Cahn-Hilliard type that constitutes an extension of the classical Caginalp model for nonisothermal phase transitions with a conserved order parameter. The system couples a Cahn-Hilliard type equation with source term for the order parameter with the universal balance law of internal energy. In place of the standard Fourier form, the constitutive law of the heat flux is assumed in the form given by the theory developed by Green and Naghdi, which accounts for a possible thermal memory of the evolution. This has the consequence that the balance law of internal energy becomes a second-order in time equation for the thermal displacement or freezing index, that is, a primitive with respect to time of the temperature. Another particular feature of our system is the presence of the source term in the equation for the order parameter, which entails additional mathematical difficulties because the mass conservation of the order parameter, typical of the classic Cahn-Hilliard equation, is no longer satisfied. In this paper, we analyze the case that the double-well potential driving the evolution of the phase transition is differentiable, either (in the regular case) on the whole set of reals or (in the singular logarithmic case) on a finite open interval; nondifferentiable cases like the double obstacle potential are excluded from the analysis. We prove the Fréchet differentiability of the control-to-state operator between suitable Banach spaces for both the regular and the logarithmic cases and establish the solvability of the corresponding adjoint systems in order to derive the associated first-order necessary optimality conditions for the optimal control problem.

math.OC↗

arXiv2023

On a phase field model for RNA-Protein dynamics

A phase field model which describes the formation of protein-RNA complexes subject to phase segregation is analyzed. A single protein, two RNA species, and two complexes are considered. Protein and RNA species are governed by coupled reaction-diffusion equations which also depend on the two complexes. The latter ones are driven by two Cahn-Hilliard equations with Flory-Huggins potential and reaction terms depending on the solution variables. The resulting nonlinear coupled system is equipped with no-flux boundary conditions and suitable initial conditions. The former ones entail some mass conservation constraints which are also due to the nature of the reaction terms. The existence of global weak solutions in a bounded (two- or) three-dimensional domain is established. In dimension two, some weighted-in-time regularity properties are shown. In particular, the complexes instantaneously get uniformly separated from the pure phases. Taking advantage of this result, a unique continuation property is proven. Among the many technical difficulties, the most significant one arises from the fact that the two complexes are initially nonexistent, so their initial conditions are zero i.e., they start from a pure phase. Thus we must solve, in particular, a system of two coupled Cahn-Hilliard equations with singular potential and nonlinear sources without the usual assumption on the initial datum, i.e., the initial phase cannot be pure. This novelty requires a new approach to estimate the chemical potential in a suitable $L^p(L^2)$-space with $p\in(1,2)$. This technique can be extended to other models like, for instance, the well-known Cahn-Hilliard-Oono equation.

math.AP↗

arXiv2022

Unpolarized Transverse Momentum Distributions from a global fit of Drell-Yan and Semi-Inclusive Deep-Inelastic Scattering data

We present an extraction of unpolarized transverse-momentum-dependent parton distribution and fragmentation functions based on more than two thousands data points from several experiments for two different processes: semi-inclusive deep-inelastic scattering and Drell-Yan production of lepton pairs. The baseline analysis is performed with a Monte Carlo replica method resumming large logarithms at N3LL accuracy. The resulting description of the data is very good ($χ^2/N_{\rm dat} = 1.06$). For semi-inclusive deep-inelastic scattering, predictions for multiplicities are normalized by factors that cure the discrepancy with data introduced by higher-order perturbative corrections.

hep-ph↗

arXiv2022

Phenomenology of gluon TMDs from $η_{b,c}$ production

We present the potential of $η_{b,c}$ production in proton collisions to access the gluon transverse-momentum dependent parton distributions (TMDs). In particular, we explore the phenomenology of the unpolarized and linearly-polarized gluon TMDs in unpolarized collisions for different kinematic settings, and the potential of a fixed-target experiment at the LHC.

hep-ph↗

arXiv2022

Optimal control of a nonconserved phase field model of Caginalp type with thermal memory and double obstacle potential

In this paper, we investigate optimal control problems for a nonlinear state system which constitutes a version of the Caginalp phase field system modeling nonisothermal phase transitions with a nonconserved order parameter that takes thermal memory into account. The state system, which is a first-order approximation of a thermodynamically consistent system, is inspired by the theories developed by Green and Naghdi. It consists of two nonlinearly coupled partial differential equations that govern the phase dynamics and the universal balance law for internal energy, written in terms of the phase variable and the so-called thermal displacement, i.e., a primitive with respect to time of temperature. We extend recent results obtained for optimal control problems in which the free energy governing the phase transition was differentiable (i.e., of regular or logarithmic type) to the nonsmooth case of a double obstacle potential. As is well known, in this nondifferentiable case standard methods to establish the existence of appropriate Lagrange multipliers fail. This difficulty is overcome utilizing of the so-called deep quench approach. Namely,the double obstacle potential is approximated by a family of (differentiable) logarithmic ones for which the existence of optimal controls and first-order necessary conditions of optimality in terms of the adjoint state variables and a variational inequality are known. By proving appropriate bounds for the adjoint states of the approximating systems, we can pass to the limit in the corresponding first-order necessary conditions, thereby establishing meaningful first-order necessary optimality conditions also for the case of the double obstacle potential.

math.OC↗

arXiv2022

Phase field topology optimisation for 4D printing

This work concerns a structural topology optimisation problem for 4D printing based on the phase field approach. The concept of 4D printing as a targeted evolution of 3D printed structures can be realised in a two-step process. One first fabricates a 3D object with multi-material active composites and apply external loads in the programming stage. Then, a change in an environmental stimulus and the removal of loads cause the object deform in the programmed stage. The dynamic transition between the original and deformed shapes is achieved with appropriate applications of the stimulus. The mathematical interest is to find an optimal distribution for the materials such that the 3D printed object achieves a targeted configuration in the programmed stage as best as possible. Casting the problem as a PDE-constrained minimisation problem, we consider a vector-valued order parameter representing the volume fractions of the different materials in the composite as a control variable. We prove the existence of optimal designs and formulate first order necessary conditions for minimisers. Moreover, by suitable asymptotic techniques, we relate our approach to a sharp interface description. Finally, the theoretical results are validated by several numerical simulations both in two and three space dimensions.

math.OC↗

arXiv2022

Existence of weak solutions to multiphase Cahn-Hilliard-Darcy and Cahn-Hilliard-Brinkman models for stratified tumor growth with chemotaxis and general source terms

We investigate a multiphase Cahn-Hilliard model for tumor growth with general source terms. The multiphase approach allows us to consider multiple cell types and multiple chemical species (oxygen and/or nutrients) that are consumed by the tumor. Compared to classical two-phase tumor growth models, the multiphase model can be used to describe a stratified tumor exhibiting several layers of tissue (e.g., proliferating, quiescent and necrotic tissue) more precisely. Our model consists of a convective Cahn-Hilliard type equation to describe the tumor evolution, a velocity equation for the associated volume-averaged velocity field, and a convective reaction-diffusion type equation to describe the density of the chemical species. The velocity equation is either represented by Darcy's law or by the Brinkman equation. We first construct a global weak solution of the multiphase Cahn-Hilliard-Brinkman model. After that, we show that such weak solutions of the system converge to a weak solution of the multiphase Cahn-Hilliard-Darcy system as the viscosities tend to zero in some suitable sense. This means that the existence of a global weak solution to the Cahn-Hilliard-Darcy system is also established.

math.AP↗

arXiv2022

Cahn-Hilliard-Brinkman model for tumor growth with possibly singular potentials

We analyze a phase field model for tumor growth consisting of a Cahn-Hilliard-Brinkman system, ruling the evolution of the tumor mass, coupled with an advection-reaction-diffusion equation for a chemical species acting as a nutrient. The main novelty of the paper concerns the discussion of the existence of weak solutions to the system covering all the meaningful cases for the nonlinear potentials; in particular,the typical choices given by the regular, the logarithmic, and the double obstacle potentials are admitted in our treatise. Compared to previous results related to similar models, we suggest, instead of the classical no-flux condition, a Dirichlet boundary condition for the chemical potential appearing in the Cahn-Hilliard-type equation. Besides, abstract growth conditions for the source terms that may depend on the solution variables are postulated.

math.AP↗

arXiv2022

On a Cahn-Hilliard-Keller-Segel model with generalized logistic source describing tumor growth

We propose a new type of diffuse interface model describing the evolution of a tumor mass under the effects of a chemical substance (e.g., a nutrient or a drug). The process is described by utilizing the variables $φ$, an order parameter representing the local proportion of tumor cells, and $σ$, representing the concentration of the chemical. The order parameter $φ$ is assumed to satisfy a suitable form of the Cahn-Hilliard equation with mass source and logarithmic potential of Flory-Huggins type (or generalizations of it). The chemical concentration $σ$ satisfies a reaction-diffusion equation where the cross-diffusion term has the same expression as in the celebrated Keller-Segel model. In this respect, the model we propose represents a new coupling between the Cahn-Hilliard equation and a subsystem of the Keller-Segel model. We believe that, compared to other models, this choice is more effective in capturing the chemotactic effects that may occur in tumor growth dynamics (chemically induced tumor evolution and consumption of nutrient/drug by tumor cells). Note that, in order to prevent finite time blowup of $σ$, we assume a chemical source term of logistic type. Our main mathematical result is devoted to proving existence of weak solutions in a rather general setting that covers both the two- and three- dimensional cases. Under more restrictive assumptions on coefficients and data, and in some cases on the spatial dimension, we prove various regularity results. Finally, in a proper class of smooth solutions we show uniqueness and continuous dependence on the initial data in a number of significant cases.

math.AP↗

arXiv2021

Overhang penalization in additive manufacturing via phase field structural topology optimization with anisotropic energies

A phase field approach for structural topology optimization with application to additive manufacturing is analyzed. The main novelty is the penalization of overhangs (regions of the design that require underlying support structures during construction) with anisotropic energy functionals. Convex and non-convex examples are provided, with the latter showcasing oscillatory behavior along the object boundary termed the dripping effect in the literature. We provide a rigorous mathematical analysis for the structural topology optimization problem with convex and non-continuously-differentiable anisotropies, deriving the first order necessary optimality condition using subdifferential calculus. Via formally matched asymptotic expansions we connect our approach with previous works in the literature based on a sharp interface shape optimization description. Finally, we present several numerical results to demonstrate the advantages of our proposed approach in penalizing overhang developments.

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