arXiv subjects

Andreas Hallqvist

Publications and source records attributed to Andreas Hallqvist.

3 recordsLinked to original sources

arXiv2026

What Matters is the Prompt: Prompt Sensitivity and Prompt Generation in Foundation Models for Lung Nodule Segmentation

Lung nodule segmentation in computed tomography is essential for extracting clinically relevant information for lung cancer assessment and treatment planning. Foundation models have shown notable segmentation capabilities, but state-of-the-art approaches often depend on input prompts, such as points or boxes, making their performance sensitive to prompt quality and placement. Understanding the limitations and constraints of prompt-based foundation models is therefore essential for designing reliable medical image segmentation solutions. In this work, we investigate how prompt quality affects foundation models performance for lung nodule segmentation. We further propose a synthetic prompt-generation model to test if the dependence on manually provided prompts can be mitigated by generating synthetic prompts that can also improve segmentation performance. Perturbation experiments show that bounding box prompts generally outperform point prompts, while latest specialized medical imaging models achieve better performance than general purpose ones. The proposed approach obtains a Dice coefficient of 0.85, suggesting that synthetic prompt generation as a promising strategy for lung nodule segmentation with foundation models.

eess.IV↗

arXiv2026

CT-CLIP Representations for Multimodal Lung Cancer Survival Prediction

Accurate prognosis prediction is important for treatment planning in lung cancer, but deep learning-driven survival modelling is often limited by the scarcity of curated imaging cohorts with reliable outcome data. This study evaluates whether representations from a domain-specific foundation model can be used for multimodal survival prediction in data-constrained clinical settings. We assess the foundation model CT-CLIP as a feature extractor for pretreatment computed tomography images and clinical variables from 242 diagnosed lung cancer patients. The evaluation includes adaptation strategies based on frozen encoders, full fine-tuning, and low-rank adaptation, together with modality ablations and comparisons with clinical and multimodal baselines. The results show that a frozen CT-CLIP model combined with a trainable lightweight survival head outperforms the clinical baseline and achieves comparable or improved performance relative to other multimodal approaches, and separates patients into clinically meaningful high- and low-risk groups.

cs.CV↗

arXiv2026

Medical Image Understanding Improves Survival Prediction via Visual Instruction Tuning

Accurate prognostication and risk estimation are essential for guiding clinical decision-making and optimizing patient management. While radiologist-assessed features from CT scans provide valuable indicators of disease severity and outcomes, interpreting such images requires expert knowledge, and translating rich visual information into textual summaries inevitably leads to information loss. In this work, we propose a vision-language framework for 3D CT image understanding that leverages large-scale open-sourced CT images paired with radiology reports through visual instruction tuning. This pre-training enables the model to learn clinically meaningful visual-textual representations, which can then be adapted to downstream survival prediction tasks. By incorporating a survival prediction head on top of the pre-trained model, our approach improves survival prediction from CT images and clinical data while generating clinically meaningful language responses to predefined questions. Experimental results demonstrate that our method outperforms baseline methods in survival prediction, particularly, when clinical data alone is less predictive. The code will be released upon acceptance.

cs.CV↗