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Andrew King

Publications and source records attributed to Andrew King.

At least 37 records · Page 2Linked to original sources

A Machine Learning Case Study for AI-empowered echocardiography of Intensive Care Unit Patients in low- and middle-income countries

We present a Machine Learning (ML) study case to illustrate the challenges of clinical translation for a real-time AI-empowered echocardiography system with data of ICU patients in LMICs. Such ML case study includes data preparation, curation and labelling from 2D Ultrasound videos of 31 ICU patients in LMICs and model selection, validation and deployment of three thinner neural networks to classify apical four-chamber view. Results of the ML heuristics showed the promising implementation, validation and application of thinner networks to classify 4CV with limited datasets. We conclude this work mentioning the need for (a) datasets to improve diversity of demographics, diseases, and (b) the need of further investigations of thinner models to be run and implemented in low-cost hardware to be clinically translated in the ICU in LMICs. The code and other resources to reproduce this work are available at https://github.com/vital-ultrasound/ai-assisted-echocardiography-for-low-resource-countries.

physics.med-ph↗

Ultraluminous X-ray sources

The study of ultraluminous X-ray sources (ULXs) has changed dramatically over the last decade. In this review we first describe the most important observations of ULXs in various wavebands, and across multiple scales in space and time. We discuss recent progress and current unanswered questions. We consider the range of current theories of ULX properties in the light of this observational progress. Applying these models to neutron-star ULXs offers particularly stringent tests, as this is the unique case where the mass of the accretor is effectively fixed.

astro-ph.HE↗

Angular Momentum Transfer in QPEs from Galaxy Nuclei

A suggested model for quasi--periodic eruptions (QPEs) from galaxy nuclei invokes a white dwarf in an eccentric orbit about the central massive black hole. I point out that the extreme mass ratio allows the presence of strong Lindblad resonances in the accretion disc. These are important for the stability of mass transfer, and may trigger the eruptions themselves by rapidly transferring angular momentum from the accretion disc (which is likely to be eccentric itself) to the orbiting WD companion at pericentre. I consider the effects of von Zeipel--Lidov--Kozai (ZLK) cycles caused by a perturber on a more distant orbit about the central black hole. I show that ZLK cycles can change the orbital periods of QPE systems on timescales much shorter than the mass transfer time, as seen in ASASSN-14ko, and produce correlated short--term variations of their mass transfer rates and orbital periods, as recently observed in GSN~069. Further monitoring of these sources should constrain the parameters of any perturbing companions. This in turn may constrain the nature of the events creating QPE systems, and perhaps give major insights into how the central black holes in low--mass galaxies are able to grow.

astro-ph.HE↗

Robust and accelerated single-spike spiking neural network training with applicability to challenging temporal tasks

Spiking neural networks (SNNs), particularly the single-spike variant in which neurons spike at most once, are considerably more energy efficient than standard artificial neural networks (ANNs). However, single-spike SSNs are difficult to train due to their dynamic and non-differentiable nature, where current solutions are either slow or suffer from training instabilities. These networks have also been critiqued for their limited computational applicability such as being unsuitable for time-series datasets. We propose a new model for training single-spike SNNs which mitigates the aforementioned training issues and obtains competitive results across various image and neuromorphic datasets, with up to a $13.98\times$ training speedup and up to an $81\%$ reduction in spikes compared to the multi-spike SNN. Notably, our model performs on par with multi-spike SNNs in challenging tasks involving neuromorphic time-series datasets, demonstrating a broader computational role for single-spike SNNs than previously believed.

cs.NE↗

Quasi--Periodic Eruptions from Galaxy Nuclei

I consider quasi--periodic eruptions (QPEs) from galaxy nuclei. All the known cases fit naturally into a picture of accretion from white dwarfs (WDs) in highly eccentric orbits about the central black holes which decay through gravitational wave emission. I argue that ESO 243-39 HLX--1 is a QPE source at an earlier stages of this evolution, with correspondingly a longer period, more extreme eccentricity, and significantly more massive WD donor. I show explicitly that mass transfer in QPE systems is always highly stable, despite recent claims to the contrary in the literature. This stability may explain the alternating long--short eruptions seen in some QPE sources. As the WD orbit decays, the eruptions occupy larger fractions of the orbit and become brighter, making searches for quasi--periodicities in bright low--mass galaxy nuclei potentially fruitful.

astro-ph.GA↗

Current Status of Hard X-Ray Nano-Tomography on the Transmission Microscope at the ANATOMIX Beamline

The transmission X-ray microscope (TXM) on the Anatomix beamline welcomed its first nano-tomography users in 2019. The instrument is based on diffractive optics and works in the range of energies from 7 keV to 21 keV. A spatial resolution in 3D volumes of better than 100 nm can be achieved. The design allows imaging samples in air, and local tomography as well as off-axis tomography scans are possible. Scans below and above K-edges can be made to access elemental distribution. The TXM serves materials science and the bio-medical field.

physics.ins-det↗

AGN Light Echoes and the Accretion Disc Self-Gravity Limit

Accretion disc theory predicts that an AGN disc becomes self-gravitating and breaks up into stars at an outer radius $R_{\rm sg}$ ~ 12 light-days, with effectively no free parameter. We present evidence that the longer observed AGN light echoes are all close to 12d in the AGN rest frames. These observations give a stringent test of AGN disc theory. Further monitoring should offer insight into the formation angular momentum of the gas forming the disc. For distant AGN, observed lags significantly longer than 12d give lower limits on their redshifts.

astro-ph.GA↗

One for the Future: measuring the mass transfer rate in the ULX M82 X-2 by using orbital period changes will take millenia

Bachetti et al. (2021) have recently claimed to measure the mass transfer rate in the pulsing ULX system M82 X-2 by following the change of its orbital period over 7 yr. We reiterate the known point that this method cannot give a reliable result (or even necessarily predict the correct sign of long-term period change) without a far longer baseline (here $\gg 1000$~yr) or for systems with a much higher long-term mass transfer rate ($\gg 10^{-4} \rm M_{\odot}/{\rm yr}$), if they exist. Applying the method of Bachetti et al. (2021) to measured orbital period derivatives predicts that the well-studied quiescent X-ray transients XTEJ1118+480, A0620-00 should currently instead have steady accretion discs and be bright X-ray sources, while Nova Muscae 1991 should be still brighter (a ULX). But all three sources are observed to be extremely faint. We conclude that there is no evidence to support the high mass transfer rate that Bachetti et al. (2021) find for M82 X-2 as it is deduced from period noise not related to the binary evolution.

astro-ph.HE↗

Dwarf Galaxies and the Black-Hole Scaling Relations

The sample of dwarf galaxies with measured central black hole masses $M$ and velocity dispersions $σ$ has recently doubled, and gives a close fit to the extrapolation of the $M \propto σ$ relation for more massive galaxies. We argue that this is difficult to reconcile with suggestions that the scaling relations between galaxies and their central black holes are simply a statistical consequence of assembly through repeated mergers. This predicts black hole masses significantly larger than those observed in dwarf galaxies unless the initial distribution of uncorrelated seed black hole and stellar masses is confined to much smaller masses than earlier assumed. It also predicts a noticeable flattening of the $M \propto σ$ relation for dwarfs, to $M \propto σ^2$ compared with the observed $M \propto σ^4$. In contrast black hole feedback predicts that black hole masses tend towards a universal $M \propto σ^4$ relation in all galaxies, and correctly gives the properties of powerful outflows recently observed in dwarf galaxies. These considerations emphasize once again that the fundamental physical black-hole -- galaxy scaling relation is between $M$ and $σ$. The relation of $M$ to the bulge mass $M_b$ is acausal, and depends on the quite independent connection between $M_b$ and $σ$ set by stellar feedback.

astro-ph.GA↗

Probabilistic 3D surface reconstruction from sparse MRI information

Surface reconstruction from magnetic resonance (MR) imaging data is indispensable in medical image analysis and clinical research. A reliable and effective reconstruction tool should: be fast in prediction of accurate well localised and high resolution models, evaluate prediction uncertainty, work with as little input data as possible. Current deep learning state of the art (SOTA) 3D reconstruction methods, however, often only produce shapes of limited variability positioned in a canonical position or lack uncertainty evaluation. In this paper, we present a novel probabilistic deep learning approach for concurrent 3D surface reconstruction from sparse 2D MR image data and aleatoric uncertainty prediction. Our method is capable of reconstructing large surface meshes from three quasi-orthogonal MR imaging slices from limited training sets whilst modelling the location of each mesh vertex through a Gaussian distribution. Prior shape information is encoded using a built-in linear principal component analysis (PCA) model. Extensive experiments on cardiac MR data show that our probabilistic approach successfully assesses prediction uncertainty while at the same time qualitatively and quantitatively outperforms SOTA methods in shape prediction. Compared to SOTA, we are capable of properly localising and orientating the prediction via the use of a spatially aware neural network.

cs.CV↗

Improving performance of logical qubits by parameter tuning and topology compensation

Optimization or sampling of arbitrary pairwise Ising models, in a quantum annealing protocol of constrained interaction topology, can be enabled by a minor-embedding procedure. The logical problem of interest is transformed to a physical (device programmable) problem, where one binary variable is represented by a logical qubit consisting of multiple physical qubits. In this paper we discuss tuning of this transformation for the cases of clique, biclique, and cubic lattice problems on the D-Wave 2000Q quantum computer. We demonstrate parameter tuning protocols in spin glasses and channel communication problems, focusing on anneal duration, chain strength, and mapping from the result on physical qubits back to the logical space. Inhomogeneities in effective coupling strength arising from minor-embedding are shown to be mitigated by an efficient reweighting of programmed couplings, accounting for logical qubit topology.

quant-ph↗

Pulsing and Non-Pulsing ULXs: the Iceberg Emerges

We show that ultraluminous X-ray sources (ULXs) with coherent X-ray pulsing (PULXs) probably have neutron-star spin axes significantly misaligned from their central accretion discs. Scattering in the funnels collimating their emission and producing their apparent super-Eddington luminosities is the most likely origin of the observed correlation between pulse fraction and X-ray photon energy. Pulsing is suppressed in systems with the neutron-star spin closely aligned to the inner disc, explaining why some ULXs show cyclotron features indicating strong magnetic fields, but do not pulse. We suggest that alignment (or conceivably, field suppression through accretion) generally occurs within a fairly short fraction of the ULX lifetime, so that most neutron-star ULXs become unpulsed. As a result we further suggest that almost all ULXs actually have neutron-star accretors, rather than black holes or white dwarfs, reflecting their progenitor high-mass X-ray binary and supersoft X-ray source populations.

astro-ph.HE↗

GSN 069 -- A Tidal Disruption Near-Miss

I suggest that the quasiperiodic ultrasoft X-ray eruptions recently observed from the galaxy GSN 069 may result from accretion from a low-mass white dwarf in a highly eccentric orbit about its central black hole. At 0.21M_sun, this star was probably the core of a captured red giant. Such events should occur in significant numbers as less extreme outcomes of whatever process leads to tidal disruption events. I show that gravitational radiation losses can drive the observed mass transfer rate, and that the precession of the white dwarf orbit may be detectable in X-rays as a superorbital quasiperiod P_super ~ 2 d. The very short lifetime of the current event, and the likelihood that similar ones involving more massive stars would be less observable, together suggest that stars may transfer mass to the low-mass SMBH in this and similar galaxies at a total rate potentially making a significant contribution to their masses. A similar or even much greater inflow rate would be unobservable in most galaxies. I discuss the implications for SMBH mass growth.

astro-ph.HE↗

Supermassive Black Hole Demographics: Evading $M - σ$

We consider black hole - galaxy coevolution using simple analytic arguments. We focus on the fact that several supermassive black holes are known with masses significantly larger than suggested by the $M - σ$ relation, sometimes also with rather small stellar masses. We show that these are likely to have descended from extremely compact `blue nugget' galaxies born at high redshift, whose very high velocity dispersions allowed the black holes to reach unusually large masses. Subsequent interactions reduce the velocity dispersion, so the black holes lie above the usual $M - σ$ relation and expel a large fraction of the bulge gas (as in WISE J104222.11+164115.3) that would otherwise make stars, before ending at low redshift as very massive holes in galaxies with relatively low stellar masses, such as NGC 4889 and NGC 1600. We further suggest the possible existence of two new types of galaxy: low-mass dwarfs whose central black holes lie below the $M - σ$ relation at low redshift, and galaxies consisting of very massive ($\gtrsim 10^{11}$M$_{\odot}$) black holes with extremely small stellar masses. This second group would be very difficult to detect electromagnetically, but potentially offer targets of considerable interest for LISA.

astro-ph.GA↗

No magnetars in ULXs

We consider the current observed ensemble of pulsing ultraluminous X-ray sources (PULXs). We show that all of their observed properties (luminosity, spin period, and spinup rate) are consistent with emission from magnetic neutron stars with fields in the usual range $10^{11} - 10^{13}\, {\rm G}$, which is collimated (`beamed') by the outflow from an accretion disc supplied with mass at a super-Eddington rate, but ejecting the excess, in the way familiar for other (non-pulsing) ULXs. The observed properties are inconsistent with magnetar-strength fields in all cases. We point out that all proposed pictures of magnetar formation suggest that they are unlikely to be members of binary systems, in agreement with the observation that all confirmed magnetars are single. The presence of magnetars in ULXs is therefore improbable, in line with our conclusions above.

astro-ph.HE↗

Warm absorbers: supermassive black hole feeding, and Compton-thick AGN

Warm absorbers are found in many AGN and consist of clouds moving at moderate radial velocities, showing complex ionization structures and having moderate to large column densities. Using 1D numerical calculations, we confirm earlier suggestions that the energy released by an AGN pushes the surrounding gas outward in a bubble until this reaches transparency. Typical AGN episode durations of $5\times 10^4$ yr supply enough energy for this, except in very gas-rich and/or very compact galaxies, such as those in the early Universe. In those galaxies, the AGN might remain hidden for many periods of activity, hiding the black hole growth. The typical radii of $0.1-1$ kpc, velocities of $100-1000$ km s$^{-1}$ and resulting optical depths are consistent with observations of warm absorbers. The resulting structure is a natural outcome of outflows driven by AGN buried in an optically thick gas envelope, and has a total mass comparable to the final $M -σ$ mass the central supermassive black hole will eventually reach.These results suggest that AGN can feed very efficiently by agitating this surrounding dense material. This may not be easy to observe, as this gas is Compton thick along many sightlines. The infall may produce episodic star formation in the centre, building up nuclear star clusters simultaneously with the growth of the central black hole.

astro-ph.GA↗

An ultra-fast inflow in the luminous Seyfert PG1211+143

Blueshifted absorption lines in the X-ray spectra of AGN show that ultra-fast outflows with typical velocities $v \sim 0.1c$ are a common feature of these luminous objects. Such powerful AGN winds offer an explanation of the observed M-$σ$ relation linking the mass of the supermassive black hole and the velocity dispersion in the galaxy's stellar bulge. An extended XMM-Newton study of the luminous Seyfert galaxy PG1211+143 recently revealed a variable multi-velocity wind. Here we report the detection of a short-lived, ultra-fast inflow during the same observation. Previous reports of inflows used single absorption lines with uncertain identifications, but this new result identifies an array of resonance absorption lines of highly ionised Fe, Ca, Ar, S and Si, sharing a common redshift when compared with a grid of realistic photoionization spectra. The redshifted absorption arises in a column of highly ionized matter close to the black hole, with a line-of-sight velocity, $v \sim 0.3c$, inconsistent with the standard picture of a plane circular accretion disc. This may represent the first direct evidence for chaotic accretion in AGN, where accretion discs are generally misaligned to the black hole spin. For sufficient inclinations, the Lense-Thirring effect can break the discs into discrete rings, which then precess, collide and shock, causing near free-fall of gas towards the black hole. The observed accretion rate for the reported infall is comparable to the hard X-ray luminosity in PG1211+143, suggesting that direct infall may be a significant contributor to inner disc accretion.

astro-ph.HE↗

Circumbinary discs around merging stellar-mass black holes

A circumbinary disc around a pair of merging stellar-mass black holes may be shocked and heated during the recoil of the merged hole, causing a near-simultaneous electromagnetic counterpart to the gravitational wave event. The shocks occur around the recoil radius, where the disc orbital velocity is equal to the recoil velocity. The amount of mass present near this radius at the time of the merger is critical in determining how much radiation is released. We explore the evolution of a circumbinary disc in two limits. First, we consider an accretion disc that feels no torque from the binary. The disc does not survive until the merger unless there is a dead zone, a region of low turbulence. Even with the dead zone, the surface density in this case may be small. Second, we consider a disc that feels a strong binary torque that prevents accretion on to the binary. In this case there is significantly more mass in regions of interest at the time of the merger. A dead zone in this disc increases the mass close to the recoil radius. For typical binary-disc parameters we expect accretion to be significantly slowed by the resonant torque from the binary, and for a dead zone to be present. We conclude that provided significant mass orbits the binary after the formation of the black hole binary and that the radiation produced in recoil shocks can escape the flow efficiently, there is likely to be an observable electromagnetic signal from black hole binary mergers.

astro-ph.HE↗