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Andrew Sanchez

Publications and source records attributed to Andrew Sanchez.

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Magnetoresistance ratio of a point-like contact with a 1 nm wide domain wall at different MFP asymmetries

This work presents a unified theoretical framework for spin-resolved electron transport in magnetic point contacts (PCs) in nanoscale dimensions. This work advances existing research by presenting a model which seamlessly transitions between Sharvin ballistic and Maxwell-Holm diffusive limits across the wide range of relevant contact sizes without incorporating empirical fitting factors. We analyzed the magnetoresistance (MR) of magnetic PCs formed with two ferromagnetic monodomains that may have parallel and antiparallel magnetization alignment, forming a constrained domain wall approximately 1.0 nm wide. The calculated MR exhibits strong dependence on scaling parameter (normalized contact radius), ratios of spin-dependent mean free paths, and Fermi wave-vectors. Furthermore, the calculated MR exhibits physically meaningful behavior over a wide range of spin-asymmetry parameters. In most regimes, the MR decreases with increasing normalized point-contact radius, becoming negative at some conditions. These results demonstrate that nanoscaled magnetic PCs have great efficiency in terms of magnetoresistnace change and promising for application due to their simplicity.

cond-mat.mes-hall

Teaching large language models to reason like expert diagnosticians

Differential diagnosis is an iterative process that integrates patient information with broader medical knowledge. Clinical case series such as the NEJM Clinicopathologic Conferences (CPCs), published continuously since 1923, feature expert physicians who demonstrate diagnostic reasoning to peers, and have been used for decades to evaluate AI. However, prior AI evaluations have largely focused on final diagnostic accuracy rather than nuanced clinical reasoning. Here, we introduce Dr. CaBot, an agentic AI system that emulates an expert diagnostician by generating written and narrated slide-based presentations from an initial case description alone. CaBot recently generated the first AI diagnosis published in the 100+ year history of the NEJM CPCs. In blinded evaluations, physicians misclassified the source of the differential (CaBot vs. physician-written) in 46/62 (74%) of trials and rated them favorably across quality dimensions. When tasked with solving cases for 72 patients with undiagnosed disease from the NIH Undiagnosed Diseases Network, CaBot identified the working diagnosis in 50/72 (69%) of cases from referral notes alone. To promote transparency and research, we also developed CPC-Bench, a physician-validated benchmark based on 7,102 CPCs and 47,648 questions across 10 tasks. We show that CaBot outperforms frontier models on CPC-Bench, and release both CaBot and CPC-Bench publicly to foster progress in clinical AI.

cs.AI

Surface Processing and Discharge-Conditioning of High Voltage Electrodes for the Ra EDM Experiment

The Ra EDM experiment uses a pair of high voltage electrodes to search for the atomic electric dipole moment of $^{225}$Ra. We use identical, plane-parallel electrodes with a primary high gradient surface of 200 mm$^2$ to generate reversible DC electric fields. Our statistical sensitivity is linearly proportional to the electric field strength in the electrode gap. We adapted surface decontamination and processing techniques from accelerator physics literature to chemical polish and clean a suite of newly fabricated large-grain niobium and grade-2 titanium electrodes. Three pairs of niobium electrodes and one pair of titanium electrodes were discharge-conditioned with a custom high voltage test station at electric field strengths as high as $+52.5$ kV/mm and $-51.5$ kV/mm over electrode gap sizes ranging from 0.4 mm to 2.5 mm. One pair of large-grain niobium electrodes was discharge-conditioned and validated to operate at $\pm 20$ kV/mm with steady-state leakage current $\leq 25$ pA ($1\sigma$) and a polarity-averaged $98 \pm 19$ discharges per hour. These electrodes were installed in the Ra EDM experimental apparatus, replacing a copper electrode pair, and were revalidated to $\pm 20$ kV/mm. The niobium electrodes perform at an electric field strength 3.1 times larger than the legacy copper electrodes and are ultimately limited by the maximum output of our 30 kV bipolar power supply.

physics.ins-det

High Energy Electron Confinement in a Magnetic Cusp Configuration

We report experimental results validating the concept that plasma confinement is enhanced in a magnetic cusp configuration when beta (plasma pressure/magnetic field pressure) is order of unity. This enhancement is required for a fusion power reactor based on cusp confinement to be feasible. The magnetic cusp configuration possesses a critical advantage: the plasma is stable to large scale perturbations. However, early work indicated that plasma loss rates in a reactor based on a cusp configuration were too large for net power production. Grad and others theorized that at high beta a sharp boundary would form between the plasma and the magnetic field, leading to substantially smaller loss rates. The current experiment validates this theoretical conjecture for the first time and represents critical progress toward the Polywell fusion concept which combines a high beta cusp configuration with an electrostatic fusion for a compact, economical, power-producing nuclear fusion reactor.

physics.plasm-ph