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Andrey Vlasov

Publications and source records attributed to Andrey Vlasov.

8 recordsLinked to original sources

Optimal monophasic, asymmetric electric field pulses for selective transcranial magnetic stimulation (TMS) with minimised power and coil heating

Transcranial magnetic stimulation (TMS) with asymmetric electric field pulses, such as monophasic, offers directional selectivity for neural activation but requires excessive energy. Previous pulse shape optimisation has been limited to symmetric pulses or heavily constrained variations of conventional waveforms without achieving general optimality in energy efficiency or neural selectivity. We implemented an optimisation framework that incorporates neuron model activation constraints and flexible control of pulse asymmetry. The optimised electric field waveforms achieved up to 92 % and 88 % reduction in energy loss and thus coil heating respectively compared to conventional monophasic pulses and previously improved monophasic-equivalent pulses. In the human experiments, OUR pulses showed similar motor thresholds to monophasic pulses in both AP and PA directions with significantly lower energy loss, particularly in the AP direction. Moreover, there was a significant MEP latency difference of (1.79 +/- 0.41) ms between AP and PA direction with OUR pulses, which suggests directional selectivity. Our framework successfully identified highly energy-efficient asymmetric pulses for directionally-selective neural engagement. These pulses can enable selective rapid-rate repetitive TMS protocols with reduced power consumption and coil heating, with potential benefits for precision and potency of neuro-modulation.

eess.SY

Shocks in nova outflows. II. Synchrotron radio emission

The discovery of GeV gamma-rays from classical novae indicates that shocks and relativistic particle acceleration are energetically key in these events. Further evidence for shocks comes from thermal keV X-ray emission and an early peak in the radio light curve on a timescale of months with a brightness temperature which is too high to result from freely expanding photo-ionized gas. Paper I developed a one dimensional model for the thermal emission from nova shocks. This work concluded that the shock-powered radio peak cannot be thermal if line cooling operates in the post-shock gas at the rate determined by collisional ionization equilibrium. Here we extend this calculation to include non-thermal synchrotron emission. Applying our model to three classical novae, we constrain the amplification of the magnetic field $ε_B$ and the efficiency $ε_e$ of accelerating relativistic electrons of characteristic Lorentz factor $γ\sim 100$. If the shocks are radiative (low velocity $v_{\rm sh} \lesssim 1000$ km s$^{-1}$) and cover a large solid angle of the nova outflow, as likely characterize those producing gamma-rays, then values of $ε_e \sim 0.01-0.1$ are required to achieve the peak radio brightness for $ε_B = 10^{-2}$. Such high efficiencies exclude secondary pairs from pion decay as the source of the radio-emitting particles, instead favoring the direct acceleration of electrons at the shock. If the radio-emitting shocks are instead adiabatic (high velocity), as likely characterize those responsible for the thermal X-rays, then much higher brightness temperatures are possible, allowing the radio-emitting shocks to cover a smaller outflow solid angle.

astro-ph.HE

Novae as Tevatrons: Prospects for CTA and IceCube

The discovery of novae as sources of ~GeV gamma-rays highlights the key role of shocks and relativistic particle acceleration in these transient systems. Although there is evidence for a spectral cut-off above energies ~1-100 GeV at particular epochs in some novae, the maximum particle energy achieved in these accelerators has remained an open question. The high densities of the nova ejecta (~10 orders of magnitude larger than in supernova remnants) render the gas far upstream of the shock neutral and shielded from ionizing radiation. The amplification of the magnetic field needed for diffusive shock acceleration requires ionized gas, thus confining the acceleration process to a narrow photo-ionized layer immediately ahead of the shock. Based on the growth rate in this layer of the hybrid non-resonant cosmic ray current-driven instability (considering also ion-neutral damping), we quantify the maximum particle energy, Emax, across the range of shock velocities and upstream densities of interest. We find values of Emax ~ 10 GeV - 10 TeV, which are broadly consistent with the inferred spectral cut-offs, but which could also in principle lead to emission extending to higher energies >100 GeV accessible to atmosphere Cherenkov telescopes, such as the planned Cherenkov Telescope Array (CTA). Detecting TeV neutrinos with IceCube in hadronic scenarios appears to be more challenging, although the prospects are improved if the shock power during the earliest, densest phases of the nova outburst is higher than is implied by the observed GeV light curves, due to downscattering of the gamma-rays by electrons within the ejecta. Novae provide ideal nearby laboratories to study magnetic field amplification and the onset of cosmic ray acceleration, because other time-dependent sources (e.g. radio supernovae) typically occur too distant to detect as gamma-ray sources.

astro-ph.HE

Screening properties of four mesoscale smoothed charge models, with application to dissipative particle dynamics

We extend our previous study [J. Chem. Phys. 138, 204907 (2013)] to quantify the screening properties of four mesoscale smoothed charge models used in dissipative particle dynamics. Using a combination of the hypernetted chain integral equation closure and the random phase approximation, we identify regions where the models exhibit a real-valued screening length, and the extent to which this agrees with the Debye length in the physical system. We find that the second moment of the smoothed charge distribution is a good predictor of this behaviour. We are thus able to recommend a consistent set of parameters for the models.

cond-mat.soft

Screening properties of Gaussian electrolyte models, with application to dissipative particle dynamics

We investigate the screening properties of Gaussian charge models of electrolyte solutions by analysing the asymptotic behaviour of the pair distribution functions. We use a combination of Monte-Carlo simulations with the hyper-netted chain integral equation closure, and the random phase approximation, to establish the conditions under which a screening length is well defined and the extent to which it matches the expected Debye length. For practical applications, for example in dissipative particle dynamics, we are able to summarise our results in succinct rules-of-thumb which can be used for mesoscale modeling of electrolyte solutions. We thereby establish a solid foundation for future work, such as the systematic incorporation of specific ion effects.

cond-mat.soft

What do we learn from CMB observations

We give an account, at non-expert and quantitative level, of physics behind the CMB temperature anisotropy and polarization and their peculiar features. We discuss, in particular, how cosmological parameters are determined from the CMB measurements and their combinations with other observations. We emphasize that CMB is the major source of information on the primordial density perturbations and, possibly, gravitational waves, and discuss the implication for our understanding of the extremely early Universe.

astro-ph.CO

Automated search for star clusters in large multiband surveys: II. Discovery and investigation of open clusters in the Galactic plane

Automated search for star clusters in J,H,K_s data from 2MASS catalog has been performed using the method developed by Koposov et. al (2008). We have found and verified 153 new clusters in the interval of the galactic latitude -24 < b < 24 degrees. Color excesses E(B-V), distance moduli and ages were determined for 130 new and 14 yet-unstudied known clusters. In this paper, we publish a catalog of coordinates, diameters, and main parameters of all the clusters under study. A special web-site available at http://ocl.sai.msu.ru has been developed to facilitate dissemination and scientific usage of the results.

astro-ph.GA

Complanart of polynomial equations

In this paper we study polynomial maps of vector spaces and their eigenvectors and eigenvalues. The new quantity called complanart is defined. Complanarts determine complanarity of solution vectors of systems of polynomial equations. Evaluation of complanart is reduced to evaluation of resultants. As in linear case, the pattern of eigenvectors defines the phase diagram of associated differential equation. Theory of such differential equations arise naturally as extension of Lyapunov's theory of stability for solutions of differential equations. The results of this work have a number of potential applications: from solving non-linear differential equations and calculating non-linear exponents to taking non-Gaussian integrals.

math-ph