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Angelo Kastroulis

Publications and source records attributed to Angelo Kastroulis.

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The Atoms of the Score: Record-Level versus In-Engine Composite Evaluation of Clinical Quality Language

Clinical Quality Language (CQL) engines serve two axes: decision support (evaluate one patient, now) and quality measurement (score a population). The composite score is rarely the end product, because the individual determinations behind it are what let a score be inspected, attributed, and acted on. Two architectures follow from where aggregation happens: one computes the composite inside the engine over the whole store (no data movement); the other evaluates individual records and lets the composite be totaled externally, keeping every intermediate available. Mercury is a purpose-built CQL database engine of the second kind. It treats CQL evaluation as a database problem -- FHIR stored in a compact binary encoding keyed patient-first, indexes derived from what CQL retrieves filter on, a planner selecting access paths, CQL as the query language -- rather than as in-memory interpretation over a generic FHIR store. We evaluate Mercury 2.0.1 against Blaze 1.10.1, among the fastest CQL evaluators, using Blaze's own published benchmark suite on identical AWS hardware over a 100,000-patient Synthea corpus (112.3M resources).

cs.DB

Introducing Hermes: Executing Clinical Quality Language (CQL) at over 66 Million Resources per Second (inexpensively)

Clinical Quality Language (CQL) has emerged as a standard for rule representation in Clinical Decision Support (CDS) and Electronic Clinical Quality Measurement (eCQM) in healthcare. While open-source reference implementations and a few commercial engines exist, there is still a market need for high-performance engines that can execute CQL queries on the scales of millions of patients. We introduce the \Hermes{} engine as the world's fastest commercial CQL execution engine.

cs.DB