arXiv subjects

Anika Hannemann

Publications and source records attributed to Anika Hannemann.

6 recordsLinked to original sources

arXiv2026

Understanding the Resource Cost of Fully Homomorphic Encryption in Quantum Federated Learning

Quantum Federated Learning (QFL) enables distributed training of Quantum Machine Learning (QML) models by sharing model gradients instead of raw data. However, these gradients can still expose sensitive user information. To enhance privacy, homomorphic encryption of parameters has been proposed as a solution in QFL and related frameworks. In this work, we evaluate the overhead introduced by Fully Homomorphic Encryption (FHE) in QFL setups and assess its feasibility for real-world applications. We implemented various QML models including a Quantum Convolutional Neural Network (QCNN) trained in a federated environment with parameters encrypted using the CKKS scheme. This work marks the first QCNN trained in a federated setting with CKKS-encrypted parameters. Models of varying architectures were trained to predict brain tumors from MRI scans. The experiments reveal that memory and communication overhead remain substantial, making FHE challenging to deploy. Minimizing overhead requires reducing the number of model parameters, which, however, leads to a decline in classification performance, introducing a trade-off between privacy and model complexity.

cs.CR↗

arXiv2025

PP-GWAS: Privacy Preserving Multi-Site Genome-wide Association Studies

Genome-wide association studies are pivotal in understanding the genetic underpinnings of complex traits and diseases. Collaborative, multi-site GWAS aim to enhance statistical power but face obstacles due to the sensitive nature of genomic data sharing. Current state-of-the-art methods provide a privacy-focused approach utilizing computationally expensive methods such as Secure Multi-Party Computation and Homomorphic Encryption. In this context, we present a novel algorithm PP-GWAS designed to improve upon existing standards in terms of computational efficiency and scalability without sacrificing data privacy. This algorithm employs randomized encoding within a distributed architecture to perform stacked ridge regression on a Linear Mixed Model to ensure rigorous analysis. Experimental evaluation with real world and synthetic data indicates that PP-GWAS can achieve computational speeds twice as fast as similar state-of-the-art algorithms while using lesser computational resources, all while adhering to a robust security model that caters to an all-but-one semi-honest adversary setting. We have assessed its performance using various datasets, emphasizing its potential in facilitating more efficient and private genomic analyses.

cs.CR↗

arXiv2025

Federated Learning in Genetics: Extended Analysis of Accuracy, Performance and Privacy Trade-offs

Machine learning on large-scale genomic or transcriptomic data is important for many novel health applications. For example, precision medicine tailors medical treatments to patients on the basis of individual biomarkers, cellular and molecular states, etc. However, the data required is sensitive, voluminous, heterogeneous, and typically distributed across locations where dedicated machine learning hardware is not available. Due to privacy and regulatory reasons, it is also problematic to aggregate all data at a trusted third party. Federated learning is a promising solution to this dilemma, because it enables decentralized, collaborative machine learning without exchanging raw data. In this paper, we perform comparative experiments with the federated learning frameworks TensorFlow Federated and Flower. Our test case is the training of disease prognosis and cell type classification models. We train the models with distributed transcriptomic data, considering both data heterogeneity and architectural heterogeneity. We measure model quality, robustness against privacy-enhancing noise and computational performance. We evaluate the resource overhead of a federated system from both client and global perspectives and assess benefits and limitations. Each of the federated learning frameworks has different strengths. However, our experiments confirm that both frameworks can readily build models on transcriptomic data, without transferring personal raw data to a third party with abundant computational resources. This paper is the extended version of https://link.springer.com/chapter/10.1007/978-3-031-63772-8_26.

cs.LG↗

arXiv2024

Private, Efficient and Scalable Kernel Learning for Medical Image Analysis

Medical imaging is key in modern medicine. From magnetic resonance imaging (MRI) to microscopic imaging for blood cell detection, diagnostic medical imaging reveals vital insights into patient health. To predict diseases or provide individualized therapies, machine learning techniques like kernel methods have been widely used. Nevertheless, there are multiple challenges for implementing kernel methods. Medical image data often originates from various hospitals and cannot be combined due to privacy concerns, and the high dimensionality of image data presents another significant obstacle. While randomised encoding offers a promising direction, existing methods often struggle with a trade-off between accuracy and efficiency. Addressing the need for efficient privacy-preserving methods on distributed image data, we introduce OKRA (Orthonormal K-fRAmes), a novel randomized encoding-based approach for kernel-based machine learning. This technique, tailored for widely used kernel functions, significantly enhances scalability and speed compared to current state-of-the-art solutions. Through experiments conducted on various clinical image datasets, we evaluated model quality, computational performance, and resource overhead. Additionally, our method outperforms comparable approaches

cs.CR↗

arXiv2023

Is Homomorphic Encryption Feasible for Smart Mobility?

Smart mobility is a promising approach to meet urban transport needs in an environmentally and and user-friendly way. Smart mobility computes itineraries with multiple means of transportation, e.g., trams, rental bikes or electric scooters, according to customer preferences. A mobility platform cares for reservations, connecting transports, invoicing and billing. This requires sharing sensible personal data with multiple parties, and puts data privacy at risk. In this paper, we investigate if fully homomorphic encryption (FHE) can be applied in practice to mitigate such privacy issues. FHE allows to calculate on encrypted data, without having to decrypt it first. We implemented three typical distributed computations in a smart mobility scenario with SEAL, a recent programming library for FHE. With this implementation, we have measured memory consumption and execution times for three variants of distributed transactions, that are representative for a wide range of smart mobility tasks. Our evaluation shows, that FHE is indeed applicable to smart mobility: With today's processing capabilities, state-of-the-art FHE increases a smart mobility transaction by about 100 milliseconds and less than 3 microcents.

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arXiv2023

A Privacy-Preserving Federated Learning Approach for Kernel methods

It is challenging to implement Kernel methods, if the data sources are distributed and cannot be joined at a trusted third party for privacy reasons. It is even more challenging, if the use case rules out privacy-preserving approaches that introduce noise. An example for such a use case is machine learning on clinical data. To realize exact privacy preserving computation of kernel methods, we propose FLAKE, a Federated Learning Approach for KErnel methods on horizontally distributed data. With FLAKE, the data sources mask their data so that a centralized instance can compute a Gram matrix without compromising privacy. The Gram matrix allows to calculate many kernel matrices, which can be used to train kernel-based machine learning algorithms such as Support Vector Machines. We prove that FLAKE prevents an adversary from learning the input data or the number of input features under a semi-honest threat model. Experiments on clinical and synthetic data confirm that FLAKE is outperforming the accuracy and efficiency of comparable methods. The time needed to mask the data and to compute the Gram matrix is several orders of magnitude less than the time a Support Vector Machine needs to be trained. Thus, FLAKE can be applied to many use cases.

cs.LG↗