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Anqi Wu

Publications and source records attributed to Anqi Wu.

At least 19 recordsLinked to original sources

Crayotter: Traceable Multi-Agent Workflows for Long-Form Video Editing

Long-form video editing over heterogeneous footage requires agents to coordinate source selection, multimodal analysis, timeline construction, narration and subtitle alignment, rendering, and revision while exposing intermediate state for inspection and repair. We present Crayotter, an open-source multimodal multi-agent demo system for prompt-driven long-form video editing. Crayotter organizes production around coverage-aware material preparation, artifact-grounded editing research, and tool-grounded timeline execution. Across these stages, retrieval reports, video analyses, editing blueprints, scheduler events, tool calls, intermediate renders, and final exports are treated as first-class artifacts rather than hidden transient state. The workbench supports local assets, agent-assisted retrieval, progress monitoring, artifact preview, failure diagnosis, interrupted-job resumption, and resource-aware asynchronous execution for long-running workflows. In a 23-theme evaluation, Crayotter achieves the highest human overall score (3.40/5) among the compared systems, with its largest margins in theme alignment, narrative coherence, and editing smoothness. These results show that long-horizon video editing agents can be made traceable, inspectable, and practically controllable through observable production artifacts. Code, traces, and examples are publicly available at https://github.com/idwts/Crayotter.

cs.CV

BehaviorVLM: Unified Finetuning-Free Behavioral Understanding with Vision-Language Reasoning

Understanding freely moving animal behavior is central to neuroscience, where pose estimation and behavioral understanding form the foundation for linking neural activity to natural actions. Yet both tasks still depend heavily on human annotation or unstable unsupervised pipelines, limiting scalability and reproducibility. We present BehaviorVLM, a unified vision-language framework for pose estimation and behavioral understanding that requires no task-specific finetuning and minimal human labeling by guiding pretrained Vision-Language Models (VLMs) through detailed, explicit, and verifiable reasoning steps. For pose estimation, we leverage quantum-dot-grounded behavioral data and propose a multi-stage pipeline that integrates temporal, spatial, and cross-view reasoning. This design greatly reduces human annotation effort, exposes low-confidence labels through geometric checks such as reprojection error, and produces labels that can later be filtered, corrected, or used to fine-tune downstream pose models. For behavioral understanding, we propose a pipeline that integrates deep embedded clustering for over-segmented behavior discovery, VLM-based per-clip video captioning, and LLM-based reasoning to merge and semantically label behavioral segments. The behavioral pipeline can operate directly from visual information and does not require keypoints to segment behavior. Together, these components enable scalable, interpretable, and label-light analysis of multi-animal behavior.

cs.CV

Learning When to Look: On-Demand Keypoint-Video Fusion for Animal Behavior Analysis

Understanding animal behavior from video is essential for neuroscience research. Modern laboratories typically collect two complementary data streams: skeletal keypoints from pose estimation tools and raw video recordings. Keypoint-based methods are efficient but suffer from geometric ambiguity, environmental blindness, and sensitivity to occlusions. Video-based methods capture rich context but require processing every frame, making them impractical for the hundreds of hours of recordings that modern experiments produce. We introduce LookAgain, a multimodal framework that combines the efficiency of keypoints with the representational power of video through on-demand visual grounding. During training, LookAgain uses dense visual features to pretrain a motion encoder and to train a gating module that learns which frames require visual context. During inference, this gating module activates visual processing only when keypoint signals are ambiguous, while maintaining performance comparable to using all frames. Experiments on single-animal and multi-animal benchmarks show that LookAgain achieves strong performance with significantly reduced computational cost, enabling high-quality behavior analysis on long-duration recordings.

q-bio.QM

A hitchhiker's guide to Poisson gradient estimation

Poisson-distributed latent variable models are widely used in computational neuroscience, but differentiating through discrete stochastic samples remains challenging. Two approaches address this: *Exponential Arrival Time* (EAT) simulation and *Gumbel-SoftMax* (GSM) relaxation. We provide the first systematic comparison of these methods, along with practical guidance for practitioners. Our main technical contribution is a modification to the EAT method that theoretically guarantees an unbiased first moment (exactly matching the firing rate), and reduces second-moment bias. We evaluate these methods on their distributional fidelity, gradient quality, and performance on two tasks: (1) variational autoencoders with Poisson latents, and (2) partially observable generalized linear models, where latent neural connectivity must be inferred from observed spike trains. Across all metrics, our modified EAT method exhibits better overall performance (often comparable to exact gradients), and substantially higher robustness to hyperparameter choices. These results extend to over-dispersed Negative Binomial latents, where modified EAT again performs best. However, only GSM generalizes to arbitrary non-Poisson distributions, including the under-dispersed regime. Together, our results clarify the trade-offs between these methods and offer concrete recommendations for practitioners working with Poisson latent variable models.

stat.ML

A Factorized Low-Rank RNN Framework for Uncovering Independent Neural Latent Dynamics and Connectivity

Low-rank recurrent neural networks (lrRNNs) are a class of models that uncover low-dimensional latent dynamics underlying neural population activity. Although their functional connectivity is low-rank, it lacks independence interpretations, making it difficult to assign distinct computational roles to different latent dimensions. To address this, we propose the Factored Recurrent Neural Network (FacRNN), a generative lrRNN framework that assumes group-wise independence among latent dynamics while allowing flexible within-group entanglement. These independent latent groups allow latent dynamics to evolve separately, but are internally rich for complex computation. We reformulate the lrRNN under a variational autoencoder (VAE) framework, enabling us to introduce a partial correlation penalty that encourages independence between groups of latent dimensions. Experiments on synthetic, monkey M1, and mouse voltage imaging data show that FacRNN consistently improves the disentanglement and interpretability of learned neural latent trajectories in low-dimensional space and low-rank connectivity over baseline lrRNNs that do not encourage group-wise independence.

q-bio.NC

Distributional Inverse Reinforcement Learning

We propose a distributional framework for offline Inverse Reinforcement Learning (IRL) that jointly models uncertainty over reward functions and full distributions of returns. Unlike conventional IRL approaches that recover a deterministic reward estimate or match only expected returns, our method captures richer structure in expert behavior, particularly in learning the reward distribution, by minimizing first-order stochastic dominance (FSD) violations and thus integrating distortion risk measures (DRMs) into policy learning, enabling the recovery of both reward distributions and distribution-aware policies. This formulation is well-suited for behavior analysis and risk-aware imitation learning. Theoretical analysis shows that the algorithm converges with $\mathcal{O}(\varepsilon^{-2})$ iteration complexity. Empirical results on synthetic benchmarks, real-world neurobehavioral data, and MuJoCo control tasks demonstrate that our method recovers expressive reward representations and achieves state-of-the-art performance.

cs.LG

Uncovering Semantic Selectivity of Latent Groups in Higher Visual Cortex with Mutual Information-Guided Diffusion

Understanding how neural populations in higher visual areas encode object-centered visual information remains a central challenge in computational neuroscience. Prior works have investigated representational alignment between artificial neural networks and the visual cortex. Nevertheless, these findings are indirect and offer limited insights to the structure of neural populations themselves. Similarly, decoding-based methods have quantified semantic features from neural populations but have not uncovered their underlying organizations. This leaves open a scientific question: "how feature-specific visual information is distributed across neural populations in higher visual areas, and whether it is organized into structured, semantically meaningful subspaces." To tackle this problem, we present MIG-Vis, a method that leverages the generative power of diffusion models to visualize and validate the visual-semantic attributes encoded in neural latent subspaces. Our method first uses a variational autoencoder to infer a group-wise disentangled neural latent subspace from neural populations. Subsequently, we propose a mutual information (MI)-guided diffusion synthesis procedure to visualize the specific visual-semantic features encoded by each latent group. We validate MIG-Vis on multi-session neural spiking datasets from the inferior temporal (IT) cortex of two macaques. The synthesized results demonstrate that our method identifies neural latent groups with clear semantic selectivity to diverse visual features, including object pose, inter-category transformations, and intra-class content. These findings provide direct, interpretable evidence of structured semantic representation in the higher visual cortex and advance our understanding of its encoding principles.

q-bio.NC

Hierarchical Diffusion Motion Planning with Task-Conditioned Uncertainty-Aware Priors

We propose a novel hierarchical diffusion planner that embeds task and motion structure directly into the noise model. Unlike standard diffusion-based planners that rely on zero-mean, isotropic Gaussian corruption, we introduce task-conditioned structured Gaussians whose means and covariances are derived from Gaussian Process Motion Planning (GPMP), explicitly encoding trajectory smoothness and task semantics in the prior. We first generalize the standard diffusion process to biased, non-isotropic corruption with closed-form forward and posterior expressions. Building on this formulation, our hierarchical design separates prior instantiation from trajectory denoising. At the upper level, the model predicts sparse, task-centric key states and their associated timings, which instantiate a structured Gaussian prior (mean and covariance). At the lower level, the full trajectory is denoised under this fixed prior, treating the upper-level outputs as noisy observations. Experiments on Maze2D goal-reaching and KUKA block stacking show consistently higher success rates and smoother trajectories than isotropic baselines, achieving dataset-level smoothness substantially earlier during training. Ablation studies further show that explicitly structuring the corruption process provides benefits beyond neural conditioning the denoising network alone. Overall, our approach concentrates the prior's probability mass near feasible and semantically meaningful trajectories. Our project page is available at https://hta-diffusion.github.io.

cs.RO

Learning Task-Agnostic Motifs to Capture the Continuous Nature of Animal Behavior

Animals flexibly recombine a finite set of core motor motifs to meet diverse task demands, but existing behavior segmentation methods oversimplify this process by imposing discrete syllables under restrictive generative assumptions. To better capture the continuous structure of behavior generation, we introduce motif-based continuous dynamics (MCD) discovery, a framework that (1) uncovers interpretable motif sets as latent basis functions of behavior by leveraging representations of behavioral transition structure, and (2) models behavioral dynamics as continuously evolving mixtures of these motifs. We validate MCD on a multi-task gridworld, a labyrinth navigation task, and freely moving animal behavior. Across settings, it identifies reusable motif components, captures continuous compositional dynamics, and generates realistic trajectories beyond the capabilities of traditional discrete segmentation models. By providing a generative account of how complex animal behaviors emerge from dynamic combinations of fundamental motor motifs, our approach advances the quantitative study of natural behavior.

cs.LG

EmoBipedNav: Emotion-aware Social Navigation for Bipedal Robots with Deep Reinforcement Learning

This study presents an emotion-aware navigation framework -- EmoBipedNav -- using deep reinforcement learning (DRL) for bipedal robots walking in socially interactive environments. The inherent locomotion constraints of bipedal robots challenge their safe maneuvering capabilities in dynamic environments. When combined with the intricacies of social environments, including pedestrian interactions and social cues, such as emotions, these challenges become even more pronounced. To address these coupled problems, we propose a two-stage pipeline that considers both bipedal locomotion constraints and complex social environments. Specifically, social navigation scenarios are represented using sequential LiDAR grid maps (LGMs), from which we extract latent features, including collision regions, emotion-related discomfort zones, social interactions, and the spatio-temporal dynamics of evolving environments. The extracted features are directly mapped to the actions of reduced-order models (ROMs) through a DRL architecture. Furthermore, the proposed framework incorporates full-order dynamics and locomotion constraints during training, effectively accounting for tracking errors and restrictions of the locomotion controller while planning the trajectory with ROMs. Comprehensive experiments demonstrate that our approach exceeds both model-based planners and DRL-based baselines. The hardware videos and open-source code are available at https://gatech-lidar.github.io/emobipednav.github.io/.

cs.RO

A Revisit of Total Correlation in Disentangled Variational Auto-Encoder with Partial Disentanglement

A fully disentangled variational auto-encoder (VAE) aims to identify disentangled latent components from observations. However, enforcing full independence between all latent components may be too strict for certain datasets. In some cases, multiple factors may be entangled together in a non-separable manner, or a single independent semantic meaning could be represented by multiple latent components within a higher-dimensional manifold. To address such scenarios with greater flexibility, we develop the Partially Disentangled VAE (PDisVAE), which generalizes the total correlation (TC) term in fully disentangled VAEs to a partial correlation (PC) term. This framework can handle group-wise independence and can naturally reduce to either the standard VAE or the fully disentangled VAE. Validation through three synthetic experiments demonstrates the correctness and practicality of PDisVAE. When applied to real-world datasets, PDisVAE discovers valuable information that is difficult to find using fully disentangled VAEs, implying its versatility and effectiveness.

cs.LG

Inverse Reinforcement Learning with Switching Rewards and History Dependency for Characterizing Animal Behaviors

Traditional approaches to studying decision-making in neuroscience focus on simplified behavioral tasks where animals perform repetitive, stereotyped actions to receive explicit rewards. While informative, these methods constrain our understanding of decision-making to short timescale behaviors driven by explicit goals. In natural environments, animals exhibit more complex, long-term behaviors driven by intrinsic motivations that are often unobservable. Recent works in time-varying inverse reinforcement learning (IRL) aim to capture shifting motivations in long-term, freely moving behaviors. However, a crucial challenge remains: animals make decisions based on their history, not just their current state. To address this, we introduce SWIRL (SWitching IRL), a novel framework that extends traditional IRL by incorporating time-varying, history-dependent reward functions. SWIRL models long behavioral sequences as transitions between short-term decision-making processes, each governed by a unique reward function. SWIRL incorporates biologically plausible history dependency to capture how past decisions and environmental contexts shape behavior, offering a more accurate description of animal decision-making. We apply SWIRL to simulated and real-world animal behavior datasets and show that it outperforms models lacking history dependency, both quantitatively and qualitatively. This work presents the first IRL model to incorporate history-dependent policies and rewards to advance our understanding of complex, naturalistic decision-making in animals.

cs.LG

Exploring Behavior-Relevant and Disentangled Neural Dynamics with Generative Diffusion Models

Understanding the neural basis of behavior is a fundamental goal in neuroscience. Current research in large-scale neuro-behavioral data analysis often relies on decoding models, which quantify behavioral information in neural data but lack details on behavior encoding. This raises an intriguing scientific question: ``how can we enable in-depth exploration of neural representations in behavioral tasks, revealing interpretable neural dynamics associated with behaviors''. However, addressing this issue is challenging due to the varied behavioral encoding across different brain regions and mixed selectivity at the population level. To tackle this limitation, our approach, named ``BeNeDiff'', first identifies a fine-grained and disentangled neural subspace using a behavior-informed latent variable model. It then employs state-of-the-art generative diffusion models to synthesize behavior videos that interpret the neural dynamics of each latent factor. We validate the method on multi-session datasets containing widefield calcium imaging recordings across the dorsal cortex. Through guiding the diffusion model to activate individual latent factors, we verify that the neural dynamics of latent factors in the disentangled neural subspace provide interpretable quantifications of the behaviors of interest. At the same time, the neural subspace in BeNeDiff demonstrates high disentanglement and neural reconstruction quality.

q-bio.NC

Learning Time-Varying Multi-Region Brain Communications via Scalable Markovian Gaussian Processes

Understanding and constructing brain communications that capture dynamic communications across multiple regions is fundamental to modern system neuroscience, yet current methods struggle to find time-varying region-level communications or scale to large neural datasets with long recording durations. We present a novel framework using Markovian Gaussian Processes to learn brain communications with time-varying temporal delays from multi-region neural recordings, named Adaptive Delay Model (ADM). Our method combines Gaussian Processes with State Space Models and employs parallel scan inference algorithms, enabling efficient scaling to large datasets while identifying concurrent communication patterns that evolve over time. This time-varying approach captures how brain region interactions shift dynamically during cognitive processes. Validated on synthetic and multi-region neural recordings datasets, our approach discovers both the directionality and temporal dynamics of neural communication. This work advances our understanding of distributed neural computation and provides a scalable tool for analyzing dynamic brain networks.

cs.LG

Multi-Region Markovian Gaussian Process: An Efficient Method to Discover Directional Communications Across Multiple Brain Regions

Studying the complex interactions between different brain regions is crucial in neuroscience. Various statistical methods have explored the latent communication across multiple brain regions. Two main categories are the Gaussian Process (GP) and Linear Dynamical System (LDS), each with unique strengths. The GP-based approach effectively discovers latent variables with frequency bands and communication directions. Conversely, the LDS-based approach is computationally efficient but lacks powerful expressiveness in latent representation. In this study, we merge both methodologies by creating an LDS mirroring a multi-output GP, termed Multi-Region Markovian Gaussian Process (MRM-GP). Our work establishes a connection between an LDS and a multi-output GP that explicitly models frequencies and phase delays within the latent space of neural recordings. Consequently, the model achieves a linear inference cost over time points and provides an interpretable low-dimensional representation, revealing communication directions across brain regions and separating oscillatory communications into different frequency bands.

q-bio.NC

Extraction and Recovery of Spatio-Temporal Structure in Latent Dynamics Alignment with Diffusion Models

In the field of behavior-related brain computation, it is necessary to align raw neural signals against the drastic domain shift among them. A foundational framework within neuroscience research posits that trial-based neural population activities rely on low-dimensional latent dynamics, thus focusing on the latter greatly facilitates the alignment procedure. Despite this field's progress, existing methods ignore the intrinsic spatio-temporal structure during the alignment phase. Hence, their solutions usually lead to poor quality in latent dynamics structures and overall performance. To tackle this problem, we propose an alignment method ERDiff, which leverages the expressivity of the diffusion model to preserve the spatio-temporal structure of latent dynamics. Specifically, the latent dynamics structures of the source domain are first extracted by a diffusion model. Then, under the guidance of this diffusion model, such structures are well-recovered through a maximum likelihood alignment procedure in the target domain. We first demonstrate the effectiveness of our proposed method on a synthetic dataset. Then, when applied to neural recordings from the non-human primate motor cortex, under both cross-day and inter-subject settings, our method consistently manifests its capability of preserving the spatiotemporal structure of latent dynamics and outperforms existing approaches in alignment goodness-of-fit and neural decoding performance.

q-bio.NC

Learn to Teach: Sample-Efficient Privileged Learning for Humanoid Locomotion over Diverse Terrains

Humanoid robots promise transformative capabilities for industrial and service applications. While recent advances in Reinforcement Learning (RL) yield impressive results in locomotion, manipulation, and navigation, the proposed methods typically require enormous simulation samples to account for real-world variability. This work proposes a novel one-stage training framework-Learn to Teach (L2T)-which unifies teacher and student policy learning. Our approach recycles simulator samples and synchronizes the learning trajectories through shared dynamics, significantly reducing sample complexities and training time while achieving state-of-the-art performance. Furthermore, we validate the RL variant (L2T-RL) through extensive simulations and hardware tests on the Digit robot, demonstrating zero-shot sim-to-real transfer and robust performance over 12+ challenging terrains without depth estimation modules.

cs.RO

A Differentiable Partially Observable Generalized Linear Model with Forward-Backward Message Passing

The partially observable generalized linear model (POGLM) is a powerful tool for understanding neural connectivity under the assumption of existing hidden neurons. With spike trains only recorded from visible neurons, existing works use variational inference to learn POGLM meanwhile presenting the difficulty of learning this latent variable model. There are two main issues: (1) the sampled Poisson hidden spike count hinders the use of the pathwise gradient estimator in VI; and (2) the existing design of the variational model is neither expressive nor time-efficient, which further affects the performance. For (1), we propose a new differentiable POGLM, which enables the pathwise gradient estimator, better than the score function gradient estimator used in existing works. For (2), we propose the forward-backward message-passing sampling scheme for the variational model. Comprehensive experiments show that our differentiable POGLMs with our forward-backward message passing produce a better performance on one synthetic and two real-world datasets. Furthermore, our new method yields more interpretable parameters, underscoring its significance in neuroscience.

cs.LG