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Antoine Barizien

Publications and source records attributed to Antoine Barizien.

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Estimation of the lifetime distribution from fluctuations in Bellman-Harris processes

The growth of a population is often modeled as branching process where each individual at the end of its life is replaced by a certain number of offspring. An example of these branching models is the Bellman-Harris process, where the lifetime of individuals is assumed to be independent and identically distributed. Here, we are interested in the estimation of the parameters of the Bellman-Harris model, motivated by the estimation of cell division time. Lifetimes are distributed according a Gamma distribution and we follow a population that starts from a small number of individuals by performing time-resolved measurements of the population size. The exponential growth of the population size at the beginning offers an easy estimation of the mean of the lifetime. Going farther and describing lifetime variability is a challenging task however, due to the complexity of the fluctuations of non-Markovian branching processes. Using fine and recent results on these fluctuations, we describe two time-asymptotic regimes and explain how to estimate the parameters. Then, we both consider simulations and biological data to validate and discuss our method. The results described here provide a method to determine single-cell parameters from time-resolved measurements of populations without the need to track each individual or to know the details of the initial condition.

math.PR

A model for the erosion onset of a granular bed sheared by a viscous fluid

We study theoretically the erosion threshold of a granular bed forced by a viscous fluid. We first introduce a novel model of interacting particles driven on a rough substrate. It predicts a continuous transition at some threshold forcing $θ_c$, beyond which the particle current grows linearly $J\sim θ-θ_c$, in agreement with experiments. The stationary state is reached after a transient time $t_{\rm conv}$ which diverges near the transition as $t_{\rm conv}\sim |θ-θ_c|^{-z}$ with $z\approx 2.5$. The model also makes quantitative testable predictions for the drainage pattern: the distribution $P(σ)$ of local current is found to be extremely broad with $P(σ)\sim J/σ$, spatial correlations for the current are negligible in the direction transverse to forcing, but long-range parallel to it. We explain some of these features using a scaling argument and a mean-field approximation that builds an analogy with $q$-models. We discuss the relationship between our erosion model and models for the depinning transition of vortex lattices in dirty superconductors, where our results may also apply.

cond-mat.soft