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Arie Kaufman

Publications and source records attributed to Arie Kaufman.

26 records · Page 2Linked to original sources

Crowd-Assisted Polyp Annotation of Virtual Colonoscopy Videos

Virtual colonoscopy (VC) allows a radiologist to navigate through a 3D colon model reconstructed from a computed tomography scan of the abdomen, looking for polyps, the precursors of colon cancer. Polyps are seen as protrusions on the colon wall and haustral folds, visible in the VC fly-through videos. A complete review of the colon surface requires full navigation from the rectum to the cecum in antegrade and retrograde directions, which is a tedious task that takes an average of 30 minutes. Crowdsourcing is a technique for non-expert users to perform certain tasks, such as image or video annotation. In this work, we use crowdsourcing for the examination of complete VC fly-through videos for polyp annotation by non-experts. The motivation for this is to potentially help the radiologist reach a diagnosis in a shorter period of time, and provide a stronger confirmation of the eventual diagnosis. The crowdsourcing interface includes an interactive tool for the crowd to annotate suspected polyps in the video with an enclosing box. Using our workflow, we achieve an overall polyps-per-patient sensitivity of 87.88% (95.65% for polyps $\geq$5mm and 70% for polyps $<$5mm). We also demonstrate the efficacy and effectiveness of a non-expert user in detecting and annotating polyps and discuss their possibility in aiding radiologists in VC examinations.

cs.CV↗

Radiative Transport Based Flame Volume Reconstruction from Videos

We introduce a novel approach for flame volume reconstruction from videos using inexpensive charge-coupled device (CCD) consumer cameras. The approach includes an economical data capture technique using inexpensive CCD cameras. Leveraging the smear feature of the CCD chip, we present a technique for synchronizing CCD cameras while capturing flame videos from different views. Our reconstruction is based on the radiative transport equation which enables complex phenomena such as emission, extinction, and scattering to be used in the rendering process. Both the color intensity and temperature reconstructions are implemented using the CUDA parallel computing framework, which provides real-time performance and allows visualization of reconstruction results after every iteration. We present the results of our approach using real captured data and physically-based simulated data. Finally, we also compare our approach against the other state-of-the-art flame volume reconstruction methods and demonstrate the efficacy and efficiency of our approach in four different applications: (1) rendering of reconstructed flames in virtual environments, (2) rendering of reconstructed flames in augmented reality, (3) flame stylization, and (4) reconstruction of other semitransparent phenomena.

cs.CV↗

Crowdsourcing for Identification of Polyp-Free Segments in Virtual Colonoscopy Videos

Virtual colonoscopy (VC) allows a physician to virtually navigate within a reconstructed 3D colon model searching for colorectal polyps. Though VC is widely recognized as a highly sensitive and specific test for identifying polyps, one limitation is the reading time, which can take over 30 minutes per patient. Large amounts of the colon are often devoid of polyps, and a way of identifying these polyp-free segments could be of valuable use in reducing the required reading time for the interrogating radiologist. To this end, we have tested the ability of the collective crowd intelligence of non-expert workers to identify polyp candidates and polyp-free regions. We presented twenty short videos flying through a segment of a virtual colon to each worker, and the crowd was asked to determine whether or not a possible polyp was observed within that video segment. We evaluated our framework on Amazon Mechanical Turk and found that the crowd was able to achieve a sensitivity of 80.0% and specificity of 86.5% in identifying video segments which contained a clinically proven polyp. Since each polyp appeared in multiple consecutive segments, all polyps were in fact identified. Using the crowd results as a first pass, 80% of the video segments could in theory be skipped by the radiologist, equating to a significant time savings and enabling more VC examinations to be performed.

cs.HC↗

Depth Reconstruction and Computer-Aided Polyp Detection in Optical Colonoscopy Video Frames

We present a computer-aided detection algorithm for polyps in optical colonoscopy images. Polyps are the precursors to colon cancer. In the US alone, more than 14 million optical colonoscopies are performed every year, mostly to screen for polyps. Optical colonoscopy has been shown to have an approximately 25% polyp miss rate due to the convoluted folds and bends present in the colon. In this work, we present an automatic detection algorithm to detect these polyps in the optical colonoscopy images. We use a machine learning algorithm to infer a depth map for a given optical colonoscopy image and then use a detailed pre-built polyp profile to detect and delineate the boundaries of polyps in this given image. We have achieved the best recall of 84.0% and the best specificity value of 83.4%.

cs.CV↗

Multimodal Brain Visualization

Current connectivity diagrams of human brain image data are either overly complex or overly simplistic. In this work we introduce simple yet accurate interactive visual representations of multiple brain image structures and the connectivity among them. We map cortical surfaces extracted from human brain magnetic resonance imaging (MRI) data onto 2D surfaces that preserve shape (angle), extent (area), and spatial (neighborhood) information for 2D (circular disk) and 3D (spherical) mapping, split these surfaces into separate patches, and cluster functional and diffusion tractography MRI connections between pairs of these patches. The resulting visualizations are easier to compute on and more visually intuitive to interact with than the original data, and facilitate simultaneous exploration of multiple data sets, modalities, and statistical maps.

cs.GR↗

Registration of Volumetric Prostate Scans using Curvature Flow

Radiological imaging of the prostate is becoming more popular among researchers and clinicians in searching for diseases, primarily cancer. Scans might be acquired with different equipment or at different times for prognosis monitoring, with patient movement between scans, resulting in multiple datasets that need to be registered. For these cases, we introduce a method for volumetric registration using curvature flow. Multiple prostate datasets are mapped to canonical solid spheres, which are in turn aligned and registered through the use of identified landmarks on or within the gland. Theoretical proof and experimental results show that our method produces homeomorphisms with feature constraints. We provide thorough validation of our method by registering prostate scans of the same patient in different orientations, from different days and using different modes of MRI. Our method also provides the foundation for a general group-wise registration using a standard reference, defined on the complex plane, for any input. In the present context, this can be used for registering as many scans as needed for a single patient or different patients on the basis of age, weight or even malignant and non-malignant attributes to study the differences in general population. Though we present this technique with a specific application to the prostate, it is generally applicable for volumetric registration problems.

cs.GR↗

Anatomical Feature-guided Volumeric Registration of Multimodal Prostate MRI

Radiological imaging of prostate is becoming more popular among researchers and clinicians in searching for diseases, primarily cancer. Scans might be acquired at different times, with patient movement between scans, or with different equipment, resulting in multiple datasets that need to be registered. For this issue, we introduce a registration method using anatomical feature-guided mutual information. Prostate scans of the same patient taken in three different orientations are first aligned for the accurate detection of anatomical features in 3D. Then, our pipeline allows for multiple modalities registration through the use of anatomical features, such as the interior urethra of prostate and gland utricle, in a bijective way. The novelty of this approach is the application of anatomical features as the pre-specified corresponding landmarks for prostate registration. We evaluate the registration results through both artificial and clinical datasets. Registration accuracy is evaluated by performing statistical analysis of local intensity differences or spatial differences of anatomical landmarks between various MR datasets. Evaluation results demonstrate that our method statistics-significantly improves the quality of registration. Although this strategy is tested for MRI-guided brachytherapy, the preliminary results from these experiments suggest that it can be also applied to other settings such as transrectal ultrasound-guided or CT-guided therapy, where the integration of preoperative MRI may have a significant impact upon treatment planning and guidance.

cs.CV↗

From individual to population: Challenges in Medical Visualization

In this paper, we first give a high-level overview of medical visualization development over the past 30 years, focusing on key developments and the trends that they represent. During this discussion, we will refer to a number of key papers that we have also arranged on the medical visualization research timeline. Based on the overview and our observations of the field, we then identify and discuss the medical visualization research challenges that we foresee for the coming decade.

cs.GR↗