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Arturo Tozzi

Publications and source records attributed to Arturo Tozzi.

22 records · Page 2Linked to original sources

From local defects to shear-organized biofilms in tonsillar crypts via computational simulations

Biofilms in human tonsillar crypts show long term persistence with episodic dispersal that current biochemical and microbiological descriptions do not fully explain, particularly with respect to spatial localization. We introduce a biophysical framework in which tonsillar biofilm dynamics arise from the interaction between two mechanical phenomena: a Kosterlitz Thouless type defect nucleation process and a Kelvin Helmholtz type shear driven interfacial instability. Crypt geometry is modeled as a confined, heterogeneous environment that promotes mechanically persistent surface defects generated by growth induced compression. Tangential shear associated with breathing and swallowing selectively amplifies these defects, producing organized surface deformations. Numerical simulations show that only the coexistence of both mechanisms yields localized, propagating, and persistent interface structures, whereas their absence leads to diffuse, unstructured dynamics.

q-bio.QM↗

Low-Dimensional Interaction Spaces Impose Geometric Constraints On Collective Organization

Collective organization in physical, biophysical, and biological systems often emerges from many weak, local interactions, yet the resulting global structures display striking regularities and apparent limits in diversity. Existing theoretical approaches typically emphasize specific mechanisms, detailed dynamics, or energetic optimization, making it difficult to identify constraints that are independent of microscopic realization. Here we develop a general theoretical framework showing that, when effective interactions among system components compress into a low-dimensional interaction space, global organization is governed by geometric constraints rather than detailed dynamics. We formalize interaction spaces as metric manifolds derived from coarse-grained effective couplings and show that low interaction dimensionality imposes upper bounds on the number, separability, and robustness of distinct collective organizations. These results yield impossibility statements: many conceivable macroscopic organizations are excluded a priori, even when locally compatible interactions exist. The framework applies across equilibrium and nonequilibrium systems without assuming specific symmetries or conservation laws. By shifting the explanatory focus from generative mechanisms to structural constraints, this work establishes a general, geometry-based perspective on collective organization.

physics.soc-ph↗

Bridging General Relativity and Quantum Dynamics Through Finite-Resource Logical Models

A theoretical framework bridging General Relativity (GR) and Quantum Dynamics (QD) is introduced through the application of Kripke semantics and linear logic. While conventional unification efforts often rely on structural or geometrical formulations, we instead treat causality, energy and information as finite, non-replicable resources constraining physical transitions and inference. Our framework, termed Energy Constrained Linear Causality (ECLC), models quantum transitions and spacetime evolution as logically constrained processes in which each implication spends limited resources and cannot be arbitrarily duplicated or reversed. We construct a causal inference model where physical operations like quantum measurement, entanglement propagation and spacetime curvature are expressed as energy-weighted, one-time transformations. Kripke semantics formalizes the logical accessibility of physical states, capturing context-sensitive transitions and the irreversibility of information flow under finite conditions. We derive a structured method for modelling observer-dependent outcomes without invoking background-independence or high-dimensional embeddings. We formulate a series of testable predictions with controlled deviations from standard GR and QD expectations. The consumption-based irreversibility introduces an intrinsic mechanism of symmetry breaking. In GR, it restricts mutual causal accessibility by bounding inference depth with curvature-weighted energy costs. In QD, it disrupts the reciprocity of conditional probabilities and undermines time symmetry in measurement sequences. Therefore, ECLC provides a unified, resource-aware logic for describing causality, computation and emergence within a finite physical universe.

quant-ph↗

Towards the neural code endowed in cortical microcolumns

This article reports on simulations that show how, starting with a form of neural lattice structure, it is possible to reversibly generate many alternative isomers with a lower structural symmetry, which results from twisting two hexagons around a central bond.

q-bio.OT↗