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Arvind Pillai

Publications and source records attributed to Arvind Pillai.

18 recordsLinked to original sources

BALMS: Benchmarking Agentic LLMs for Longitudinal Mental Health Sensing

Mental health assessment relies on episodic self-report scales, which convert subjective states such as stress into numerical scores but provide only sparse snapshots of wellbeing. Wearable devices offer longitudinal behavioral and physiological signals for continuous, low-burden monitoring. Recent LLM-driven personal-health agents enable natural language queries over wearable signals, but mainly handle short-term, retrieval-based lookups (e.g., highest step count over a week). They do not evaluate whether agents can reason over long-term signals to predict wellbeing scores paired with evidence-grounded rationales. To address this gap, we introduce BALMS, the first systematic benchmark of LLM-based agentic systems for longitudinal mental health sensing. BALMS spans 3 real-world longitudinal datasets, 2 task families (closed-form wellbeing-score prediction and rationale generation auto-graded by an LLM-as-Judge), 3 agentic paradigms evaluated across 5 open- and closed-source LLM backbones. We find that zero-shot agents rarely outperform a simple mean baseline, except with stronger backbones or compact, semantically meaningful features. Chain-of-thought prompting improves reasoning-oriented backbones, but does not guarantee temporal grounding or numerical correctness. Together with more analysis on efficiency and temporal scaling, BALMS highlights the need for longitudinal mental health agents that selectively retrieve history, ground temporal evidence, and reason over interpretable behavioral features.

cs.CL

ReliaGate: Reliability Routing for Low-Stakes Wearable Stress Prediction

We study when a wearable stress system should surface a prediction rather than change it. In low-stakes reflection and summary settings, aggregate accuracy is insufficient because withholding can reduce error while leaving some people with little or no information. We formulate fixed-label reliability routing: after a locked classifier emits a protocol-defined stress/non-stress label, a post-hoc gate surfaces that unchanged label or withholds it as unavailable. ReliaGate assembles established confidence, signal-quality/trust, agreement, train-standardized atypicality, and train-fitted geometry cues into a post-hoc correctness score. We evaluate four wearable datasets using subject-disjoint folds, validation-selected routing, paired held-out-subject intervals, and pooled and per-subject analyses. WESAD point estimates favored ReliaGate, UBFC-Phys primary coverage/risk intervals favored ReliaGate, and E4 checks were mixed. ReliaGate provides an operational framework for studying surfaced-label error, output availability, and accepted-output distribution across subjects, without revising labels or providing clinical or finite-sample risk guarantees.

cs.LG

When Does Quality-Aware Multimodal Fusion Matter? A Leakage-Safe Diagnostic for Decision-Level Dependence

Many multimodal systems estimate the reliability of each modality and weight their contributions to the final prediction. However, it remains unclear whether these scores influence model decisions or merely correlate with performance. We propose a simple diagnostic to test whether reliability information is used during inference. After training, the model and inputs are fixed while reliability scores are permuted across test examples. If predictions depend on these scores, performance should degrade. Experiments on StressID for stress recognition and CMU-MOSEI for sentiment analysis show that permuting reliability scores leaves performance unchanged despite substantial potential gains from selecting the best modality per example. In positive controls where reliability signals identify the correct modality, the same frozen fusion rules yield significant improvements, indicating that reliability signals influence fused decisions only when they reliably predict unimodal correctness.

cs.LG

WavesFM: Hierarchical Representation Learning for Longitudinal Wearable Sensor Waveforms

Wearable sensors enable the continuous acquisition of high-resolution physiological waveforms, such as photoplethysmography and accelerometry, under free-living conditions. However, inferring health-related phenotypes from these signals presents significant challenges due to high sampling frequencies, multimodal dependencies, and extreme sequence lengths (e.g., weeks of recordings), compounded by a scarcity of ground-truth labels. To address these challenges, existing self-supervised learning (SSL) methodologies typically follow two paradigms: (1) learning rich morphological representations from short waveform segments while collapsing longitudinal dynamics through simple aggregation, or (2) modeling behavioral patterns from coarse, hand-crafted features (e.g. heart rate, step counts) spanning longer horizons but foregoing subtle, predictive signatures in raw waveforms. To bridge this gap, we propose WavesFM, a foundation model utilizing a two-stage SSL framework for longitudinal physiological data. Specifically, we decompose the learning problem into two stages: first, a segment-level encoder is pretrained to extract local embeddings from short waveforms; subsequently, a temporal encoder is trained to model the sequence of these embeddings across a multi-day horizon. This hierarchical approach overcomes the computational complexity of high-resolution, long-sequence data, allowing the overall model to capture both local signal semantics and the complex circadian and inter-day variations governing physiological dynamics. Pretrained on over 6.8M hours (N=324k individuals) of recordings for the first stage and 5.3M hours (N=10k) for the second stage, WavesFM demonstrates superior performance across 58 diverse tasks spanning demographics, lifestyle, health conditions, and medications.

cs.LG

Label-free Imaging of Single-Biomolecule Structure and Interaction by Stimulated Raman Photothermal Encoded Scattering

Current single molecule methods either rely on fluorescence or lack chemical information. Here we report stimulated Raman photothermal encoded scattering (SRPSCAT) microscopy for quantitative bond-selective imaging of single-biomolecule structures and interactions in native environments. In this approach, scattering of the target molecule is modulated by the deposited energy from stimulated Raman gain and loss processes, thereby encoding vibrational spectroscopic information. Leveraging single-molecule sensitivity of interferometric scattering, SRPSCAT can map single proteins with chemical specificity, determine their mass, and distinguish protein secondary structures based on their Raman fingerprints. Furthermore, single protein binding kinetics are quantified and the conformational dynamics of single de novo designed allosteric proteins are observed. Together, these results highlight the potential of SRPSCAT for label-free structural, functional and dynamic analysis at the single-molecule level.

physics.bio-ph

Learning Transferable Sensor Models via Language-Informed Pretraining

Modern sensing systems generate large volumes of unlabeled multivariate time-series data. This abundance of unlabeled data makes self-supervised learning (SSL) a natural approach for learning transferable representations. However, most existing approaches are optimized for reconstruction or forecasting objectives and often fail to capture the semantic structure required for downstream classification and reasoning tasks. While recent sensor-language alignment methods improve semantic generalization through captioning and zero-shot transfer, they are limited to fixed sensor configurations, such as predefined channel sets, signal lengths, or temporal resolutions, which hinders cross-domain applicability. To address these gaps, we introduce \textbf{SLIP} (\textbf{S}ensor \textbf{L}anguage-\textbf{I}nformed \textbf{P}retraining), an open-source framework for learning language-aligned representations that generalize across diverse sensor setups. SLIP integrates contrastive alignment with sensor-conditioned captioning, facilitating both discriminative understanding and generative reasoning. By repurposing a pretrained decoder-only language model via cross-attention and introducing an elegant, flexible patch-embedder, SLIP supports different temporal resolutions and variable-length input at inference time without additional retraining. Across 11 datasets, SLIP demonstrates superior performance in zero-shot transfer, signal captioning, and question answering. It achieves a 77.14% average linear-probing accuracy, a 5.93% relative improvement over strong baselines, and reaches 64.83% accuracy in sensor-based question answering.

cs.AI

LENS: LLM-Enabled Narrative Synthesis for Mental Health by Aligning Multimodal Sensing with Language Models

Multimodal health sensing offers rich behavioral signals for assessing mental health, yet translating these numerical time-series measurements into natural language remains challenging. Current LLMs cannot natively ingest long-duration sensor streams, and paired sensor-text datasets are scarce. To address these challenges, we introduce LENS, a framework that aligns multimodal sensing data with language models to generate clinically grounded mental-health narratives. LENS first constructs a large-scale dataset by transforming Ecological Momentary Assessment (EMA) responses related to depression and anxiety symptoms into natural-language descriptions, yielding over 100,000 sensor-text QA pairs from 258 participants. To enable native time-series integration, we train a patch-level encoder that projects raw sensor signals directly into an LLM's representation space. Our results show that LENS outperforms strong baselines on standard NLP metrics and task-specific measures of symptom-severity accuracy. A user study with 13 mental-health professionals further indicates that LENS-produced narratives are comprehensive and clinically meaningful. Ultimately, our approach advances LLMs as interfaces for health sensing, providing a scalable path toward models that can reason over raw behavioral signals and support downstream clinical decision-making.

cs.CL

MotionTeller: Multi-modal Integration of Wearable Time-Series with LLMs for Health and Behavioral Understanding

As wearable sensing becomes increasingly pervasive, a key challenge remains: how can we generate natural language summaries from raw physiological signals such as actigraphy - minute-level movement data collected via accelerometers? In this work, we introduce MotionTeller, a generative framework that natively integrates minute-level wearable activity data with large language models (LLMs). MotionTeller combines a pretrained actigraphy encoder with a lightweight projection module that maps behavioral embeddings into the token space of a frozen decoder-only LLM, enabling free-text, autoregressive generation of daily behavioral summaries. We construct a novel dataset of 54383 (actigraphy, text) pairs derived from real-world NHANES recordings, and train the model using cross-entropy loss with supervision only on the language tokens. MotionTeller achieves high semantic fidelity (BERTScore-F1 = 0.924) and lexical accuracy (ROUGE-1 = 0.722), outperforming prompt-based baselines by 7 percent in ROUGE-1. The average training loss converges to 0.38 by epoch 15, indicating stable optimization. Qualitative analysis confirms that MotionTeller captures circadian structure and behavioral transitions, while PCA plots reveal enhanced cluster alignment in embedding space post-training. Together, these results position MotionTeller as a scalable, interpretable system for transforming wearable sensor data into fluent, human-centered descriptions, introducing new pathways for behavioral monitoring, clinical review, and personalized health interventions.

cs.LG

Reflections from Research Roundtables at the Conference on Health, Inference, and Learning (CHIL) 2025

The 6th Annual Conference on Health, Inference, and Learning (CHIL 2025), hosted by the Association for Health Learning and Inference (AHLI), was held in person on June 25-27, 2025, at the University of California, Berkeley, in Berkeley, California, USA. As part of this year's program, we hosted Research Roundtables to catalyze collaborative, small-group dialogue around critical, timely topics at the intersection of machine learning and healthcare. Each roundtable was moderated by a team of senior and junior chairs who fostered open exchange, intellectual curiosity, and inclusive engagement. The sessions emphasized rigorous discussion of key challenges, exploration of emerging opportunities, and collective ideation toward actionable directions in the field. In total, eight roundtables were held by 19 roundtable chairs on topics of "Explainability, Interpretability, and Transparency," "Uncertainty, Bias, and Fairness," "Causality," "Domain Adaptation," "Foundation Models," "Learning from Small Medical Data," "Multimodal Methods," and "Scalable, Translational Healthcare Solutions."

cs.LG

Time2Lang: Bridging Time-Series Foundation Models and Large Language Models for Health Sensing Beyond Prompting

Large language models (LLMs) show promise for health applications when combined with behavioral sensing data. Traditional approaches convert sensor data into text prompts, but this process is prone to errors, computationally expensive, and requires domain expertise. These challenges are particularly acute when processing extended time series data. While time series foundation models (TFMs) have recently emerged as powerful tools for learning representations from temporal data, bridging TFMs and LLMs remains challenging. Here, we present Time2Lang, a framework that directly maps TFM outputs to LLM representations without intermediate text conversion. Our approach first trains on synthetic data using periodicity prediction as a pretext task, followed by evaluation on mental health classification tasks. We validate Time2Lang on two longitudinal wearable and mobile sensing datasets: daily depression prediction using step count data (17,251 days from 256 participants) and flourishing classification based on conversation duration (46 participants over 10 weeks). Time2Lang maintains near constant inference times regardless of input length, unlike traditional prompting methods. The generated embeddings preserve essential time-series characteristics such as auto-correlation. Our results demonstrate that TFMs and LLMs can be effectively integrated while minimizing information loss and enabling performance transfer across these distinct modeling paradigms. To our knowledge, we are the first to integrate a TFM and an LLM for health, thus establishing a foundation for future research combining general-purpose large models for complex healthcare tasks.

cs.LG

PaPaGei: Open Foundation Models for Optical Physiological Signals

Photoplethysmography (PPG) is the leading non-invasive technique for monitoring biosignals and cardiovascular health, with widespread adoption in both clinical settings and consumer wearable devices. While machine learning models trained on PPG signals have shown promise, they tend to be task-specific and struggle with generalization. Current research is limited by the use of single-device datasets, insufficient exploration of out-of-domain generalization, and a lack of publicly available models, which hampers reproducibility. To address these limitations, we present PaPaGei, the first open foundation model for PPG signals. The model is pre-trained on over 57,000 hours of data, comprising 20 million unlabeled PPG segments from publicly available datasets. We introduce a novel representation learning approach that leverages domain knowledge of PPG signal morphology across individuals, enabling the capture of richer representations compared to traditional contrastive learning methods. We evaluate PaPaGei against state-of-the-art time-series foundation models and self-supervised learning benchmarks across 20 tasks from 10 diverse datasets, spanning cardiovascular health, sleep disorders, pregnancy monitoring, and wellbeing assessment. Our model demonstrates superior performance, improving classification and regression metrics by 6.3% and 2.9% respectively in at least 14 tasks. Notably, PaPaGei achieves these results while being more data- and parameter-efficient, outperforming models that are 70x larger. Beyond accuracy, we examine model robustness across different skin tones, establishing a benchmark for bias evaluation in future models. PaPaGei can serve as both a feature extractor and an encoder for multimodal models, opening up new opportunities for multimodal health monitoring.

cs.LG

MindScape Study: Integrating LLM and Behavioral Sensing for Personalized AI-Driven Journaling Experiences

Mental health concerns are prevalent among college students, highlighting the need for effective interventions that promote self-awareness and holistic well-being. MindScape pioneers a novel approach to AI-powered journaling by integrating passively collected behavioral patterns such as conversational engagement, sleep, and location with Large Language Models (LLMs). This integration creates a highly personalized and context-aware journaling experience, enhancing self-awareness and well-being by embedding behavioral intelligence into AI. We present an 8-week exploratory study with 20 college students, demonstrating the MindScape app's efficacy in enhancing positive affect (7%), reducing negative affect (11%), loneliness (6%), and anxiety and depression, with a significant week-over-week decrease in PHQ-4 scores (-0.25 coefficient), alongside improvements in mindfulness (7%) and self-reflection (6%). The study highlights the advantages of contextual AI journaling, with participants particularly appreciating the tailored prompts and insights provided by the MindScape app. Our analysis also includes a comparison of responses to AI-driven contextual versus generic prompts, participant feedback insights, and proposed strategies for leveraging contextual AI journaling to improve well-being on college campuses. By showcasing the potential of contextual AI journaling to support mental health, we provide a foundation for further investigation into the effects of contextual AI journaling on mental health and well-being.

cs.HC

Contextual AI Journaling: Integrating LLM and Time Series Behavioral Sensing Technology to Promote Self-Reflection and Well-being using the MindScape App

MindScape aims to study the benefits of integrating time series behavioral patterns (e.g., conversational engagement, sleep, location) with Large Language Models (LLMs) to create a new form of contextual AI journaling, promoting self-reflection and well-being. We argue that integrating behavioral sensing in LLMs will likely lead to a new frontier in AI. In this Late-Breaking Work paper, we discuss the MindScape contextual journal App design that uses LLMs and behavioral sensing to generate contextual and personalized journaling prompts crafted to encourage self-reflection and emotional development. We also discuss the MindScape study of college students based on a preliminary user study and our upcoming study to assess the effectiveness of contextual AI journaling in promoting better well-being on college campuses. MindScape represents a new application class that embeds behavioral intelligence in AI.

cs.HC

MoodCapture: Depression Detection Using In-the-Wild Smartphone Images

MoodCapture presents a novel approach that assesses depression based on images automatically captured from the front-facing camera of smartphones as people go about their daily lives. We collect over 125,000 photos in the wild from N=177 participants diagnosed with major depressive disorder for 90 days. Images are captured naturalistically while participants respond to the PHQ-8 depression survey question: \textit{``I have felt down, depressed, or hopeless''}. Our analysis explores important image attributes, such as angle, dominant colors, location, objects, and lighting. We show that a random forest trained with face landmarks can classify samples as depressed or non-depressed and predict raw PHQ-8 scores effectively. Our post-hoc analysis provides several insights through an ablation study, feature importance analysis, and bias assessment. Importantly, we evaluate user concerns about using MoodCapture to detect depression based on sharing photos, providing critical insights into privacy concerns that inform the future design of in-the-wild image-based mental health assessment tools.

cs.HC

Social Isolation and Serious Mental Illness: The Role of Context-Aware Mobile Interventions

Social isolation is a common problem faced by individuals with serious mental illness (SMI), and current intervention approaches have limited effectiveness. This paper presents a blended intervention approach, called mobile Social Interaction Therapy by Exposure (mSITE), to address social isolation in individuals with serious mental illness. The approach combines brief in-person cognitive-behavioral therapy (CBT) with context-triggered mobile CBT interventions that are personalized using mobile sensing data. Our approach targets social behavior and is the first context-aware intervention for improving social outcomes in serious mental illness.

cs.HC

Rare Life Event Detection via Mobile Sensing Using Multi-Task Learning

Rare life events significantly impact mental health, and their detection in behavioral studies is a crucial step towards health-based interventions. We envision that mobile sensing data can be used to detect these anomalies. However, the human-centered nature of the problem, combined with the infrequency and uniqueness of these events makes it challenging for unsupervised machine learning methods. In this paper, we first investigate granger-causality between life events and human behavior using sensing data. Next, we propose a multi-task framework with an unsupervised autoencoder to capture irregular behavior, and an auxiliary sequence predictor that identifies transitions in workplace performance to contextualize events. We perform experiments using data from a mobile sensing study comprising N=126 information workers from multiple industries, spanning 10106 days with 198 rare events (<2%). Through personalized inference, we detect the exact day of a rare event with an F1 of 0.34, demonstrating that our method outperforms several baselines. Finally, we discuss the implications of our work from the context of real-world deployment.

cs.LG

A Survey of Passive Sensing for Workplace Wellbeing and Productivity

The modern workplace is undergoing a radical transformation, driven by technological advances that blur the boundaries between human capability and digital augmentation. At the forefront of this evolution is passive sensing technology - a suite of tools that quietly monitor and interpret human behavior without active user engagement. This paper examines how these technologies are reshaping our understanding of workplace dynamics, with a particular focus on employee wellbeing and productivity. Through a comprehensive review of recent research, we explore both the transformative potential and inherent challenges of passive sensing in professional environments. Our analysis reveals emerging patterns in how these technologies can support worker health and performance, while also highlighting critical gaps in current research and opportunities for future innovation. We conclude by outlining a roadmap for integrating passive sensing into future workplaces in ways that enhance human potential while preserving dignity and autonomy.

cs.HC

Personalized Step Counting Using Wearable Sensors: A Domain Adapted LSTM Network Approach

Activity monitors are widely used to measure various physical activities (PA) as an indicator of mobility, fitness and general health. Similarly, real-time monitoring of longitudinal trends in step count has significant clinical potential as a personalized measure of disease related changes in daily activity. However, inconsistent step count accuracy across vendors, body locations, and individual gait differences limits clinical utility. The tri-axial accelerometer inside PA monitors can be exploited to improve step count accuracy across devices and individuals. In this study, we hypothesize: (1) raw tri-axial sensor data can be modeled to create reliable and accurate step count, and (2) a generalized step count model can then be efficiently adapted to each unique gait pattern using very little new data. Firstly, open-source raw sensor data was used to construct a long short term memory (LSTM) deep neural network to model step count. Then we generated a new, fully independent data set using a different device and different subjects. Finally, a small amount of subject-specific data was domain adapted to produce personalized models with high individualized step count accuracy. These results suggest models trained using large freely available datasets can be adapted to patient populations where large historical data sets are rare.

cs.LG