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Arvind Pillai

Publications and source records attributed to Arvind Pillai.

At least 19 recordsLinked to original sources

Scaling Therapy Supervision: Assessing Psychotherapy Fidelity Using Large Language Models

Psychotherapy fidelity assessment measures how faithfully a therapist adheres to a treatment protocol, a critical determinant of positive patient outcomes. However, fidelity assessment is bottlenecked by manual expert review, rendering the process labor-intensive and unscalable. To scale therapy supervision and support clinician self-learning, we present an integrated application of large language models (LLMs) that automates psychotherapy fidelity workflows and generates actionable supervisory feedback from authentic, long-form clinical transcripts. We evaluate three open-weight models across multiple task decomposition configurations and reasoning strategies, demonstrating that evidence-first reasoning improves fidelity estimation. Furthermore, we establish the framework's external construct validity on an independent randomized controlled trial (RCT), where it reliably distinguishes Cognitive Behavioral Therapy (CBT) from non-CBT sessions across core therapeutic skills. Through a user study that evaluates the generated feedback, mental health experts indicate that the pipeline synthesizes actionable clinical feedback. Ultimately, our work offers a practical, scalable solution toward bridging the community mental health supervision gap.

cs.CL↗

MontageFlow: Physically Valid High Fidelity EEG Generation

Generative modeling offers a promising solution to the scarcity of labeled clinical electroencephalography (EEG) data under strict privacy constraints. Although recent generative models report substantial improvements in generation fidelity, we show that these gains conceal a categorical failure. EEG is not an arbitrary multichannel signal: each channel records the voltage difference between two scalp electrodes. So, real recordings satisfy exact linear identities among their channels. Current generators invariably violate these identities, yet this has gone unnoticed. We therefore propose MontageFlow, a flow-matching model that enforces these identities by restricting its output to signals that satisfy them. We find that ensuring validity improves fidelity too. Furthermore, to retain the EEG characteristics that oversmoothing washes out, we also condition the model on a physiological state vector encoded from the whole EEG window. For generation, this vector is drawn from a prior fitted in latent space. Across 3 large-scale benchmarks, our model improves TS-FID by 1.6-3.6$\times$ over the closest rival while ensuring validity.

cs.AI↗

Lapras: Latent Reasoning for Time Series Language Models

Time Series Language Models (TSLMs) offer a promising path toward time series understanding by reasoning over temporal signals and producing natural language answers and explanations. A common approach is Chain-of-Thought (CoT), which generates step-by-step rationales linking relevant signal patterns to final answers. Although these models learn from reference CoT traces during post-training, generating faithful descriptions of input time series at inference remains challenging. Expressing high-dimensional, continuous temporal representations in discrete language tokens may cause the model to neglect task-relevant patterns or describe them inaccurately. Because later reasoning steps build on these descriptions, early errors propagate, leading to incorrect answers with plausible explanations that are inconsistent with the input signal. We propose Lapras (Latent Post-trained Reasoning Across Series), a post-training framework that equips TSLMs with latent reasoning. A model trained with Lapras reasons through a sequence of continuous thoughts in the joint time series-language space, producing text only for the final answer. It learns this through teacher-student self-distillation, where a teacher trained on CoT reference traces reasons explicitly through text. The student aligns its hidden states with the teacher's at the answer stage, transferring the teacher's reasoning ability into its latent computation. We evaluate Lapras across four TSLM backbones on five time series question answering benchmarks. Lapras improves average F1 by up to 10.79% over explicit CoT while generating 23.9x fewer tokens. Lapras's continuous thoughts can also be decoded into readable reasoning traces via standard language decoding, preserving textual explanations. Together, these results highlight Lapras as a promising post-training paradigm for efficient, effective, and interpretable TSLM reasoning.

cs.CL↗

TimeNet: An Extensible Unified Data Infrastructure for Next-Generation Temporal Foundation Models

Temporal Foundation Models (TFMs) aim to generalize across domains, datasets, and tasks. Yet, their development remains constrained by fragmented, task-specific data formats, annotations, and processing pipelines. We introduce TimeNet, an open-source data standard and scalable infrastructure that decouples temporal data from task definitions and represents signals, metadata, annotations, and supervision in a shared, extensible data model. TimeNet supports multimodal signals with regular, irregular, or ordinal time axes and expresses different task families (including classification, forecasting, temporal localization, question answering, generation, and editing) as reusable views over the same recordings. This shared representation enables heterogeneous time-series datasets to be combined for large-scale model training across domains, modalities, and tasks. We demonstrate TimeNet by transcoding datasets with 1.5M task instances spanning diverse domains, modalities, temporal scales, and forms of supervision, while retaining practical I/O performance relative to native formats. TimeNet enables an existing TFN training pipeline to support joint training on a configurable number of heterogeneous datasets through configuration changes alone. We show this capability by training TFM across multiple datasets and tasks, obtaining a 14% F1 score improvement compared with models trained on individual datasets. These results show that TimeNet provides the data and systems foundation needed to move beyond task- and dataset-specific TFMs toward models that can learn jointly across heterogeneous domains, modalities, temporal scales, and forms of supervision from a common data model.

cs.AI↗

Learning Transferable Sensor Models via Language-Informed Pretraining

Multimodal language models have demonstrated strong semantic understanding and reasoning over physiological and behavioral signals captured from diverse healthcare sensors. However, existing sensor-language models can only process a fixed number of sensor channels at a fixed sampling rate, making them difficult to adapt to new or different sensor configurations. This inflexibility prevents models from generalizing across heterogeneous health sensing ecosystems, where data spans high-frequency wearable streams to sparse, day-scale clinical signals. To bridge this gap, we introduce SLIP (Sensor Language-Informed Pretraining), an open-source framework for learning language-aligned representations that generalize across diverse sensor setups. SLIP integrates contrastive alignment with sensor-conditioned captioning, facilitating both discriminative understanding and generative reasoning. By repurposing a pretrained decoder-only language model via cross-attention and introducing a flexible patch embedder, SLIP transfers to new sensor configurations at inference without retraining, regardless of their native sampling rate or input length. Across 11 datasets, SLIP demonstrates superior performance in retrieval, signal captioning, and question answering. It achieves a 77.14% average linear-probing accuracy, a 3.56% improvement over the strongest baseline (SensorLM). Beyond classification, SLIP supports open-vocabulary sensor captioning and question answering without any architectural modifications. Our work offers broad implications for the development of sensor-language models, utilizing cross-modal supervision to ensure more robust generalizability in health sensing applications.

cs.AI↗

TimeThink: Eliciting Compositional Reasoning in Timeseries Large Language Models

Timeseries multimodal large language models (TS-MLLMs) have recently begun leveraging the reasoning capabilities of large language models (LLMs) for question-answering tasks. However, these models often fail to capture dynamic temporal patterns, providing only implicit reasoning that lacks the underlying explanations critical for high-stakes applications like healthcare. While reinforcement learning (RL)-based timeseries language models aim to address this, they often fall short because they are trained on narrow, in-distribution data and struggle with out-of-distribution compositional questions. To address these challenges, we present TimeThink, a synthetic framework for eliciting compositional timeseries reasoning. Core timeseries primitives (e.g., trend, seasonality) are domain-independent and can be deterministically generated. Guided by this premise, TimeThink first designs a synthetic data generator that produces atomic and composite question-answer pairs, providing objective ground truth with reasoning traces. Building on this framework, TimeThink employs a reinforcement learning with verifiable rewards (RLVR) training strategy that encourages explicit reasoning. Unlike template-reliant methods, this approach enables the model to learn the underlying logic of composition rather than simply imitating traces. Extensive experiments show that TimeThink, trained only on synthetic data, significantly outperforms strong baselines on both synthetic and real-world benchmarks.

cs.AI↗

BALMS: Benchmarking Agentic LLMs for Longitudinal Mental Health Sensing

Mental health assessment relies on episodic self-report scales, which convert subjective states such as stress into numerical scores but provide only sparse snapshots of wellbeing. Wearable devices offer longitudinal behavioral and physiological signals for continuous, low-burden monitoring. Recent LLM-driven personal-health agents enable natural language queries over wearable signals, but mainly handle short-term, retrieval-based lookups (e.g., highest step count over a week). They do not evaluate whether agents can reason over long-term signals to predict wellbeing scores paired with evidence-grounded rationales. To address this gap, we introduce BALMS, the first systematic benchmark of LLM-based agentic systems for longitudinal mental health sensing. BALMS spans 3 real-world longitudinal datasets, 2 task families (closed-form wellbeing-score prediction and rationale generation auto-graded by an LLM-as-Judge), 3 agentic paradigms evaluated across 5 open- and closed-source LLM backbones. We find that zero-shot agents rarely outperform a simple mean baseline, except with stronger backbones or compact, semantically meaningful features. Chain-of-thought prompting improves reasoning-oriented backbones, but does not guarantee temporal grounding or numerical correctness. Together with more analysis on efficiency and temporal scaling, BALMS highlights the need for longitudinal mental health agents that selectively retrieve history, ground temporal evidence, and reason over interpretable behavioral features.

cs.CL↗

ReliaGate: Reliability Routing for Low-Stakes Wearable Stress Prediction

We study when a wearable stress system should surface a prediction rather than change it. In low-stakes reflection and summary settings, aggregate accuracy is insufficient because withholding can reduce error while leaving some people with little or no information. We formulate fixed-label reliability routing: after a locked classifier emits a protocol-defined stress/non-stress label, a post-hoc gate surfaces that unchanged label or withholds it as unavailable. ReliaGate assembles established confidence, signal-quality/trust, agreement, train-standardized atypicality, and train-fitted geometry cues into a post-hoc correctness score. We evaluate four wearable datasets using subject-disjoint folds, validation-selected routing, paired held-out-subject intervals, and pooled and per-subject analyses. WESAD point estimates favored ReliaGate, UBFC-Phys primary coverage/risk intervals favored ReliaGate, and E4 checks were mixed. ReliaGate provides an operational framework for studying surfaced-label error, output availability, and accepted-output distribution across subjects, without revising labels or providing clinical or finite-sample risk guarantees.

cs.LG↗

When Does Quality-Aware Multimodal Fusion Matter? A Leakage-Safe Diagnostic for Decision-Level Dependence

Many multimodal systems estimate the reliability of each modality and weight their contributions to the final prediction. However, it remains unclear whether these scores influence model decisions or merely correlate with performance. We propose a simple diagnostic to test whether reliability information is used during inference. After training, the model and inputs are fixed while reliability scores are permuted across test examples. If predictions depend on these scores, performance should degrade. Experiments on StressID for stress recognition and CMU-MOSEI for sentiment analysis show that permuting reliability scores leaves performance unchanged despite substantial potential gains from selecting the best modality per example. In positive controls where reliability signals identify the correct modality, the same frozen fusion rules yield significant improvements, indicating that reliability signals influence fused decisions only when they reliably predict unimodal correctness.

cs.LG↗

WavesFM: Hierarchical Representation Learning for Longitudinal Wearable Sensor Waveforms

Wearable sensors enable the continuous acquisition of high-resolution physiological waveforms, such as photoplethysmography and accelerometry, under free-living conditions. However, inferring health-related phenotypes from these signals presents significant challenges due to high sampling frequencies, multimodal dependencies, and extreme sequence lengths (e.g., weeks of recordings), compounded by a scarcity of ground-truth labels. To address these challenges, existing self-supervised learning (SSL) methodologies typically follow two paradigms: (1) learning rich morphological representations from short waveform segments while collapsing longitudinal dynamics through simple aggregation, or (2) modeling behavioral patterns from coarse, hand-crafted features (e.g. heart rate, step counts) spanning longer horizons but foregoing subtle, predictive signatures in raw waveforms. To bridge this gap, we propose WavesFM, a foundation model utilizing a two-stage SSL framework for longitudinal physiological data. Specifically, we decompose the learning problem into two stages: first, a segment-level encoder is pretrained to extract local embeddings from short waveforms; subsequently, a temporal encoder is trained to model the sequence of these embeddings across a multi-day horizon. This hierarchical approach overcomes the computational complexity of high-resolution, long-sequence data, allowing the overall model to capture both local signal semantics and the complex circadian and inter-day variations governing physiological dynamics. Pretrained on over 6.8M hours (N=324k individuals) of recordings for the first stage and 5.3M hours (N=10k) for the second stage, WavesFM demonstrates superior performance across 58 diverse tasks spanning demographics, lifestyle, health conditions, and medications.

cs.LG↗

LENS: LLM-Enabled Narrative Synthesis for Mental Health by Aligning Multimodal Sensing with Language Models

Multimodal health sensing offers rich behavioral signals for assessing mental health, yet translating these numerical time-series measurements into natural language remains challenging. Current LLMs cannot natively ingest long-duration sensor streams, and paired sensor-text datasets are scarce. To address these challenges, we introduce LENS, a framework that aligns multimodal sensing data with language models to generate clinically grounded mental-health narratives. LENS first constructs a large-scale dataset by transforming Ecological Momentary Assessment (EMA) responses related to depression and anxiety symptoms into natural-language descriptions, yielding over 100,000 sensor-text QA pairs from 258 participants. To enable native time-series integration, we train a patch-level encoder that projects raw sensor signals directly into an LLM's representation space. Our results show that LENS outperforms strong baselines on standard NLP metrics and task-specific measures of symptom-severity accuracy. A user study with 13 mental-health professionals further indicates that LENS-produced narratives are comprehensive and clinically meaningful. Ultimately, our approach advances LLMs as interfaces for health sensing, providing a scalable path toward models that can reason over raw behavioral signals and support downstream clinical decision-making.

cs.CL↗

Label-free Imaging of Single-Biomolecule Structure and Interaction by Stimulated Raman Photothermal Encoded Scattering

Current single molecule methods either rely on fluorescence or lack chemical information. Here we report stimulated Raman photothermal encoded scattering (SRPSCAT) microscopy for quantitative bond-selective imaging of single-biomolecule structures and interactions in native environments. In this approach, scattering of the target molecule is modulated by the deposited energy from stimulated Raman gain and loss processes, thereby encoding vibrational spectroscopic information. Leveraging single-molecule sensitivity of interferometric scattering, SRPSCAT can map single proteins with chemical specificity, determine their mass, and distinguish protein secondary structures based on their Raman fingerprints. Furthermore, single protein binding kinetics are quantified and the conformational dynamics of single de novo designed allosteric proteins are observed. Together, these results highlight the potential of SRPSCAT for label-free structural, functional and dynamic analysis at the single-molecule level.

physics.bio-ph↗

MotionTeller: Multi-modal Integration of Wearable Time-Series with LLMs for Health and Behavioral Understanding

As wearable sensing becomes increasingly pervasive, a key challenge remains: how can we generate natural language summaries from raw physiological signals such as actigraphy - minute-level movement data collected via accelerometers? In this work, we introduce MotionTeller, a generative framework that natively integrates minute-level wearable activity data with large language models (LLMs). MotionTeller combines a pretrained actigraphy encoder with a lightweight projection module that maps behavioral embeddings into the token space of a frozen decoder-only LLM, enabling free-text, autoregressive generation of daily behavioral summaries. We construct a novel dataset of 54383 (actigraphy, text) pairs derived from real-world NHANES recordings, and train the model using cross-entropy loss with supervision only on the language tokens. MotionTeller achieves high semantic fidelity (BERTScore-F1 = 0.924) and lexical accuracy (ROUGE-1 = 0.722), outperforming prompt-based baselines by 7 percent in ROUGE-1. The average training loss converges to 0.38 by epoch 15, indicating stable optimization. Qualitative analysis confirms that MotionTeller captures circadian structure and behavioral transitions, while PCA plots reveal enhanced cluster alignment in embedding space post-training. Together, these results position MotionTeller as a scalable, interpretable system for transforming wearable sensor data into fluent, human-centered descriptions, introducing new pathways for behavioral monitoring, clinical review, and personalized health interventions.

cs.LG↗

Reflections from Research Roundtables at the Conference on Health, Inference, and Learning (CHIL) 2025

The 6th Annual Conference on Health, Inference, and Learning (CHIL 2025), hosted by the Association for Health Learning and Inference (AHLI), was held in person on June 25-27, 2025, at the University of California, Berkeley, in Berkeley, California, USA. As part of this year's program, we hosted Research Roundtables to catalyze collaborative, small-group dialogue around critical, timely topics at the intersection of machine learning and healthcare. Each roundtable was moderated by a team of senior and junior chairs who fostered open exchange, intellectual curiosity, and inclusive engagement. The sessions emphasized rigorous discussion of key challenges, exploration of emerging opportunities, and collective ideation toward actionable directions in the field. In total, eight roundtables were held by 19 roundtable chairs on topics of "Explainability, Interpretability, and Transparency," "Uncertainty, Bias, and Fairness," "Causality," "Domain Adaptation," "Foundation Models," "Learning from Small Medical Data," "Multimodal Methods," and "Scalable, Translational Healthcare Solutions."

cs.LG↗

A Survey of Passive Sensing for Workplace Wellbeing and Productivity

The modern workplace is undergoing a radical transformation, driven by technological advances that blur the boundaries between human capability and digital augmentation. At the forefront of this evolution is passive sensing technology - a suite of tools that quietly monitor and interpret human behavior without active user engagement. This paper examines how these technologies are reshaping our understanding of workplace dynamics, with a particular focus on employee wellbeing and productivity. Through a comprehensive review of recent research, we explore both the transformative potential and inherent challenges of passive sensing in professional environments. Our analysis reveals emerging patterns in how these technologies can support worker health and performance, while also highlighting critical gaps in current research and opportunities for future innovation. We conclude by outlining a roadmap for integrating passive sensing into future workplaces in ways that enhance human potential while preserving dignity and autonomy.

cs.HC↗

Time2Lang: Bridging Time-Series Foundation Models and Large Language Models for Health Sensing Beyond Prompting

Large language models (LLMs) show promise for health applications when combined with behavioral sensing data. Traditional approaches convert sensor data into text prompts, but this process is prone to errors, computationally expensive, and requires domain expertise. These challenges are particularly acute when processing extended time series data. While time series foundation models (TFMs) have recently emerged as powerful tools for learning representations from temporal data, bridging TFMs and LLMs remains challenging. Here, we present Time2Lang, a framework that directly maps TFM outputs to LLM representations without intermediate text conversion. Our approach first trains on synthetic data using periodicity prediction as a pretext task, followed by evaluation on mental health classification tasks. We validate Time2Lang on two longitudinal wearable and mobile sensing datasets: daily depression prediction using step count data (17,251 days from 256 participants) and flourishing classification based on conversation duration (46 participants over 10 weeks). Time2Lang maintains near constant inference times regardless of input length, unlike traditional prompting methods. The generated embeddings preserve essential time-series characteristics such as auto-correlation. Our results demonstrate that TFMs and LLMs can be effectively integrated while minimizing information loss and enabling performance transfer across these distinct modeling paradigms. To our knowledge, we are the first to integrate a TFM and an LLM for health, thus establishing a foundation for future research combining general-purpose large models for complex healthcare tasks.

cs.LG↗

PaPaGei: Open Foundation Models for Optical Physiological Signals

Photoplethysmography (PPG) is the leading non-invasive technique for monitoring biosignals and cardiovascular health, with widespread adoption in both clinical settings and consumer wearable devices. While machine learning models trained on PPG signals have shown promise, they tend to be task-specific and struggle with generalization. Current research is limited by the use of single-device datasets, insufficient exploration of out-of-domain generalization, and a lack of publicly available models, which hampers reproducibility. To address these limitations, we present PaPaGei, the first open foundation model for PPG signals. The model is pre-trained on over 57,000 hours of data, comprising 20 million unlabeled PPG segments from publicly available datasets. We introduce a novel representation learning approach that leverages domain knowledge of PPG signal morphology across individuals, enabling the capture of richer representations compared to traditional contrastive learning methods. We evaluate PaPaGei against state-of-the-art time-series foundation models and self-supervised learning benchmarks across 20 tasks from 10 diverse datasets, spanning cardiovascular health, sleep disorders, pregnancy monitoring, and wellbeing assessment. Our model demonstrates superior performance, improving classification and regression metrics by 6.3% and 2.9% respectively in at least 14 tasks. Notably, PaPaGei achieves these results while being more data- and parameter-efficient, outperforming models that are 70x larger. Beyond accuracy, we examine model robustness across different skin tones, establishing a benchmark for bias evaluation in future models. PaPaGei can serve as both a feature extractor and an encoder for multimodal models, opening up new opportunities for multimodal health monitoring.

cs.LG↗

MindScape Study: Integrating LLM and Behavioral Sensing for Personalized AI-Driven Journaling Experiences

Mental health concerns are prevalent among college students, highlighting the need for effective interventions that promote self-awareness and holistic well-being. MindScape pioneers a novel approach to AI-powered journaling by integrating passively collected behavioral patterns such as conversational engagement, sleep, and location with Large Language Models (LLMs). This integration creates a highly personalized and context-aware journaling experience, enhancing self-awareness and well-being by embedding behavioral intelligence into AI. We present an 8-week exploratory study with 20 college students, demonstrating the MindScape app's efficacy in enhancing positive affect (7%), reducing negative affect (11%), loneliness (6%), and anxiety and depression, with a significant week-over-week decrease in PHQ-4 scores (-0.25 coefficient), alongside improvements in mindfulness (7%) and self-reflection (6%). The study highlights the advantages of contextual AI journaling, with participants particularly appreciating the tailored prompts and insights provided by the MindScape app. Our analysis also includes a comparison of responses to AI-driven contextual versus generic prompts, participant feedback insights, and proposed strategies for leveraging contextual AI journaling to improve well-being on college campuses. By showcasing the potential of contextual AI journaling to support mental health, we provide a foundation for further investigation into the effects of contextual AI journaling on mental health and well-being.

cs.HC↗