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Augustin C. Ogier

Publications and source records attributed to Augustin C. Ogier.

4 recordsLinked to original sources

Spatiotemporal graph neural process for reconstruction, extrapolation, and classification of cardiac trajectories

We present a probabilistic framework for modeling structured spatiotemporal dynamics from sparse observations, focusing on cardiac motion. Our approach integrates neural ordinary differential equations (NODEs), graph neural networks (GNNs), and neural processes into a unified model that captures uncertainty, temporal continuity, and anatomical structure. We represent dynamic systems as spatiotemporal multiplex graphs and model their latent trajectories using a GNN-parameterized vector field. Given the sparse context observations at node and edge levels, the model infers a distribution over latent initial states and control variables, enabling both interpolation and extrapolation of trajectories. We validate the method on three synthetic dynamical systems (coupled pendulum, Lorenz attractor, and Kuramoto oscillators) and two real-world cardiac imaging datasets - ACDC (N=150) and UK Biobank (N=526) - demonstrating accurate reconstruction, extrapolation, and disease classification capabilities. The model accurately reconstructs trajectories and extrapolates future cardiac cycles from a single observed cycle. It achieves state-of-the-art results on the ACDC classification task (up to 99% accuracy), and detects atrial fibrillation in UK Biobank subjects with competitive performance (up to 67% accuracy). This work introduces a flexible approach for analyzing cardiac motion and offers a foundation for graph-based learning in structured biomedical spatiotemporal time-series data.

cs.LG↗

Three-dimensional reconstruction and characterization of bladder deformations

Background and Objective: Pelvic floor disorders are prevalent diseases and patient care remains difficult as the dynamics of the pelvic floor remains poorly known. So far, only 2D dynamic observations of straining exercises at excretion are available in the clinics and the understanding of three-dimensional pelvic organs mechanical defects is not yet achievable. In this context, we proposed a complete methodology for the 3D representation of the non-reversible bladder deformations during exercises, directly combined with synthesized 3D representation of the location of the highest strain areas on the organ surface. Methods: Novel image segmentation and registration approaches have been combined with three geometrical configurations of up-to-date rapid dynamic multi-slices MRI acquisition for the reconstruction of real-time dynamic bladder volumes. Results: For the first time, we proposed real-time 3D deformation fields of the bladder under strain from in-bore forced breathing exercises. The potential of our method was assessed on eight control subjects undergoing forced breathing exercises. We obtained average volume deviation of the reconstructed dynamic volume of bladders around 2.5\% and high registration accuracy with mean distance values of 0.4 $\pm$ 0.3 mm and Hausdorff distance values of 2.2 $\pm$ 1.1 mm. Conclusions: Immediately transferable to the clinics with rapid acquisitions, the proposed framework represents a real advance in the field of pelvic floor disorders as it provides, for the first time, a proper 3D+t spatial tracking of bladder non-reversible deformations. This work is intended to be extended to patients with cavities filling and excretion to better characterize the degree of severity of pelvic floor pathologies for diagnostic assistance or in preoperative surgical planning.

cs.CV↗

Deep learning-based fully automatic segmentation of wrist cartilage in MR images

The study objective was to investigate the performance of a dedicated convolutional neural network (CNN) optimized for wrist cartilage segmentation from 2D MR images. CNN utilized a planar architecture and patch-based (PB) training approach that ensured optimal performance in the presence of a limited amount of training data. The CNN was trained and validated in twenty multi-slice MRI datasets acquired with two different coils in eleven subjects (healthy volunteers and patients). The validation included a comparison with the alternative state-of-the-art CNN methods for the segmentation of joints from MR images and the ground-truth manual segmentation. When trained on the limited training data, the CNN outperformed significantly image-based and patch-based U-Net networks. Our PB-CNN also demonstrated a good agreement with manual segmentation (Sorensen-Dice similarity coefficient (DSC) = 0.81) in the representative (central coronal) slices with large amount of cartilage tissue. Reduced performance of the network for slices with a very limited amount of cartilage tissue suggests the need for fully 3D convolutional networks to provide uniform performance across the joint. The study also assessed inter- and intra-observer variability of the manual wrist cartilage segmentation (DSC=0.78-0.88 and 0.9, respectively). The proposed deep-learning-based segmentation of the wrist cartilage from MRI could facilitate research of novel imaging markers of wrist osteoarthritis to characterize its progression and response to therapy.

physics.med-ph↗

A new geodesic-based feature for characterization of 3D shapes: application to soft tissue organ temporal deformations

In this paper, we propose a method for characterizing 3D shapes from point clouds and we show a direct application on a study of organ temporal deformations. As an example, we characterize the behavior of a bladder during a forced respiratory motion with a reduced number of 3D surface points: first, a set of equidistant points representing the vertices of quadrilateral mesh for the surface in the first time frame are tracked throughout a long dynamic MRI sequence using a Large Deformation Diffeomorphic Metric Mapping (LDDMM) framework. Second, a novel geometric feature which is invariant to scaling and rotation is proposed for characterizing the temporal organ deformations by employing an Eulerian Partial Differential Equations (PDEs) methodology. We demonstrate the robustness of our feature on both synthetic 3D shapes and realistic dynamic MRI data portraying the bladder deformation during forced respiratory motions. Promising results are obtained, showing that the proposed feature may be useful for several computer vision applications such as medical imaging, aerodynamics and robotics.

cs.CV↗