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Behnaam Aazhang

Publications and source records attributed to Behnaam Aazhang.

At least 19 recordsLinked to original sources

VISION-ICE: Video-based Interpretation and Spatial Identification of Arrhythmia Origins via Neural Networks in Intracardiac Echocardiography

Contemporary high-density mapping techniques and preoperative CT/MRI remain time and resource intensive in localizing arrhythmias. AI has been validated as a clinical decision aid in providing accurate, rapid real-time analysis of echocardiographic images. Building on this, we propose an AI-enabled framework that leverages intracardiac echocardiography (ICE), a routine part of electrophysiology procedures, to guide clinicians toward areas of arrhythmogenesis and potentially reduce procedural time. Arrhythmia source localization is formulated as a three-class classification task, distinguishing normal sinus rhythm, left-sided, and right-sided arrhythmias, based on ICE video data. We developed a 3D Convolutional Neural Network trained to discriminate among the three aforementioned classes. In ten-fold cross-validation, the model achieved a mean accuracy of 66.2% when evaluated on four previously unseen patients (substantially outperforming the 33.3% random baseline). These results demonstrate the feasibility and clinical promise of using ICE videos combined with deep learning for automated arrhythmia localization. Leveraging ICE imaging could enable faster, more targeted electrophysiological interventions and reduce the procedural burden of cardiac ablation. Future work will focus on expanding the dataset to improve model robustness and generalizability across diverse patient populations.

cs.CV

EMulator: Rapid Estimation of Complex-valued Electric Fields using a U-Net Architecture

A common factor across electromagnetic methodologies of brain stimulation is the optimization of essential dosimetry parameters, like amplitude, phase, and location of one or more transducers, which controls the stimulation strength and targeting precision. Since obtaining in-vivo measurements for the electric field distribution inside the biological tissue is challenging, physics-based simulators are used. However, these simulators are computationally expensive and time-consuming, making repeated calculations of electric fields for optimization purposes computationally prohibitive. To overcome this issue, we developed EMulator, a U-Net architecture-based regression model, for fast and robust complex electric field estimation. We trained EMulator using electric fields generated by 43 antennas placed around 14 segmented human brain models. Once trained, EMulator uses a segmented human brain model with an antenna location as an input and outputs the corresponding electric field. A representative result of our study is that, at 1.5 GHz, on the validation dataset consisting of 6 subjects, we can estimate the electric field with the magnitude of complex correlation coefficient of 0.978. Additionally, we could calculate the electric field with a mean time of 4.4 ms. On average, this is at least x1200 faster than the time required by state-of-the-art physics-based simulator COMSOL. The significance of this work is that it shows the possibility of real-time calculation of the electric field from the segmented human head model and antenna location, making it possible to optimize the amplitude, phase, and location of several different transducers with stochastic gradient descent since our model is almost everywhere differentiable.

eess.IV

Network Risk Estimation: A Risk Estimation Paradigm for Cyber Networks

Cyber networks are fundamental to many organization's infrastructure, and the size of cyber networks is increasing rapidly. Risk measurement of the entities/endpoints that make up the network via available knowledge about possible threats has been the primary tool in cyber network security. However, the dynamic behavior of the entities and the sparsity of risk-measurable points are limiting factors for risk measurement strategies, which results in poor network visibility considering the volatility of cyber networks. This work proposes a new probabilistic risk estimation approach to network security, NRE, which operates on top of existing risk measurements. The proposed method NRE extracts relationships among system components from the network connection data, models risk propagation based on the learned relationships and refines the estimates whenever risk measurements are provided. In this work, (i) the risk estimation scheme is proposed, (ii) an application of quantitative risk estimates is devised, (iii) descriptiveness of the risk estimates are compared to a pure risk measurement alternative and (iv) low computational complexity of the proposed method is illustrated capable of real-time deployment. The proposed method, NRE, is ultimately a quantitative data-driven risk assessment tool that can be used to add security aspects to existing network functions, such as routing, and it provides a robust description of the network state in the presence of threats, capable of running in real-time.

eess.SY

e-G2C: A 0.14-to-8.31 $μ$J/Inference NN-based Processor with Continuous On-chip Adaptation for Anomaly Detection and ECG Conversion from EGM

This work presents the first silicon-validated dedicated EGM-to-ECG (G2C) processor, dubbed e-G2C, featuring continuous lightweight anomaly detection, event-driven coarse/precise conversion, and on-chip adaptation. e-G2C utilizes neural network (NN) based G2C conversion and integrates 1) an architecture supporting anomaly detection and coarse/precise conversion via time multiplexing to balance the effectiveness and power, 2) an algorithm-hardware co-designed vector-wise sparsity resulting in a 1.6-1.7$\times$ speedup, 3) hybrid dataflows for enhancing near 100% utilization for normal/depth-wise(DW)/point-wise(PW) convolutions (Convs), and 4) an on-chip detection threshold adaptation engine for continuous effectiveness. The achieved 0.14-8.31 $μ$J/inference energy efficiency outperforms prior arts under similar complexity, promising real-time detection/conversion and possibly life-critical interventions

eess.SP

Spatial Transformer K-Means

K-means defines one of the most employed centroid-based clustering algorithms with performances tied to the data's embedding. Intricate data embeddings have been designed to push $K$-means performances at the cost of reduced theoretical guarantees and interpretability of the results. Instead, we propose preserving the intrinsic data space and augment K-means with a similarity measure invariant to non-rigid transformations. This enables (i) the reduction of intrinsic nuisances associated with the data, reducing the complexity of the clustering task and increasing performances and producing state-of-the-art results, (ii) clustering in the input space of the data, leading to a fully interpretable clustering algorithm, and (iii) the benefit of convergence guarantees.

cs.LG

Deep Autoencoders: From Understanding to Generalization Guarantees

A big mystery in deep learning continues to be the ability of methods to generalize when the number of model parameters is larger than the number of training examples. In this work, we take a step towards a better understanding of the underlying phenomena of Deep Autoencoders (AEs), a mainstream deep learning solution for learning compressed, interpretable, and structured data representations. In particular, we interpret how AEs approximate the data manifold by exploiting their continuous piecewise affine structure. Our reformulation of AEs provides new insights into their mapping, reconstruction guarantees, as well as an interpretation of commonly used regularization techniques. We leverage these findings to derive two new regularizations that enable AEs to capture the inherent symmetry in the data. Our regularizations leverage recent advances in the group of transformation learning to enable AEs to better approximate the data manifold without explicitly defining the group underlying the manifold. Under the assumption that the symmetry of the data can be explained by a Lie group, we prove that the regularizations ensure the generalization of the corresponding AEs. A range of experimental evaluations demonstrate that our methods outperform other state-of-the-art regularization techniques.

cs.LG

RT-RCG: Neural Network and Accelerator Search Towards Effective and Real-time ECG Reconstruction from Intracardiac Electrograms

There exists a gap in terms of the signals provided by pacemakers (i.e., intracardiac electrogram (EGM)) and the signals doctors use (i.e., 12-lead electrocardiogram (ECG)) to diagnose abnormal rhythms. Therefore, the former, even if remotely transmitted, are not sufficient for doctors to provide a precise diagnosis, let alone make a timely intervention. To close this gap and make a heuristic step towards real-time critical intervention in instant response to irregular and infrequent ventricular rhythms, we propose a new framework dubbed RT-RCG to automatically search for (1) efficient Deep Neural Network (DNN) structures and then (2)corresponding accelerators, to enable Real-Time and high-quality Reconstruction of ECG signals from EGM signals. Specifically, RT-RCG proposes a new DNN search space tailored for ECG reconstruction from EGM signals, and incorporates a differentiable acceleration search (DAS) engine to efficiently navigate over the large and discrete accelerator design space to generate optimized accelerators. Extensive experiments and ablation studies under various settings consistently validate the effectiveness of our RT-RCG. To the best of our knowledge, RT-RCG is the first to leverage neural architecture search (NAS) to simultaneously tackle both reconstruction efficacy and efficiency.

cs.AR

Interpretable Image Clustering via Diffeomorphism-Aware K-Means

We design an interpretable clustering algorithm aware of the nonlinear structure of image manifolds. Our approach leverages the interpretability of $K$-means applied in the image space while addressing its clustering performance issues. Specifically, we develop a measure of similarity between images and centroids that encompasses a general class of deformations: diffeomorphisms, rendering the clustering invariant to them. Our work leverages the Thin-Plate Spline interpolation technique to efficiently learn diffeomorphisms best characterizing the image manifolds. Extensive numerical simulations show that our approach competes with state-of-the-art methods on various datasets.

cs.CV

Reversing the Curse of Densification in mmWave Networks Through Spatial Multiplexing

The gold standard of a wireless network is that the throughput increases linearly with the density of access points (APs). However, such a linear throughput gain is suspended in the 5G mmWave network mainly due to the short communication distances in mmWave bands and the dense deployments of mmWave APs. As being operated in the interference-limited regime, the aggregate interference resulted from the increasing mmWave APs will gradually become the network performance bottleneck, which leads to the saturation of the throughput. In this paper, we propose to overcome the densification plateau of a mmWave network by employing spatial multiplexing at APs. To study the effect of spatial multiplexing on mmWave networks, we first derive the coverage probability as a function of spatial multiplexing gain. The fixed-rate coding scheme is then used to provide the network throughput. We also introduce the concept of densification gain to capture the improvement in network throughput achieved through the AP densification. Our results indicate that without the spatial multiplexing at APs, the throughput of mmWave networks will reach the plateau when the density of APs becomes sufficiently large. By enabling the spatial multiplexing at APs, however, the mmWave network can continuously harvest the throughput gains as the number of APs grows. By deriving the upper bound for the throughput of mmWave networks, we quantify the potential throughput improvement as the spatial multiplexing gain increases. However, our numerical results show that such a potential throughput gain cannot be explored by the fixed-rate coding scheme. We then demonstrate the necessity for deploying the multi-rate coding scheme in mmWave networks, especially when the spatial multiplexing gain at mmWave APs is large.

cs.IT

Nonlinear Regression with a Convolutional Encoder-Decoder for Remote Monitoring of Surface Electrocardiograms

We propose the Nonlinear Regression Convolutional Encoder-Decoder (NRCED), a novel framework for mapping a multivariate input to a multivariate output. In particular, we implement our algorithm within the scope of 12-lead surface electrocardiogram (ECG) reconstruction from intracardiac electrograms (EGM) and vice versa. The goal of performing this task is to allow for improved point-of-care monitoring of patients with an implanted device to treat cardiac pathologies. We will achieve this goal with 12-lead ECG reconstruction and by providing a new diagnostic tool for classifying atypical heartbeats. The algorithm is evaluated on a dataset retroactively collected from 14 patients. Correlation coefficients calculated between the reconstructed and the actual ECG show that the proposed NRCED method represents an efficient, accurate, and superior way to synthesize a 12-lead ECG. We can also achieve the same reconstruction accuracy with only one EGM lead as input. We also tested the model in a non-patient specific way and saw a reasonable correlation coefficient. The model was also executed in the reverse direction to produce EGM signals from a 12-lead ECG and found that the correlation was comparable to the forward direction. Lastly, we analyzed the features learned in the model and determined that the model learns an overcomplete basis of our 12-lead ECG space. We then use this basis of features to create a new diagnostic tool for identifying atypical and diseased heartbeats. This resulted in a ROC curve with an associated area under the curve value of 0.98, demonstrating excellent discrimination between the two classes.

eess.SP

Impact of Spatial Multiplexing on the Throughput of Ultra-Dense mmWave AP Networks

The operating range of a single millimeter wave (mmWave) access point (AP) is small due to the high path loss and blockage issues of the frequency band. To achieve the coverage similar to conventional sub-6GHz networks, the ultra-dense deployments of APs are required by the mmWave network. In general, the mmWave APs can be categorized into backhaul-connected APs and relay APs. Though the spatial distribution of backhaul-connected APs can be captured by the Poison point process (PPP), the desired locations of relay APs depend on the transmission protocol operated in the mmWave network. In this paper, we consider modeling the topology of mmWave AP network by incorporating the multihop protocol. We first derive the topology of AP network with the spatial multiplexing disabled for each transmission hop. Then we analyze the topology when the spatial multiplexing is enabled at the mmWave APs. To derive the network throughput, we first quantify the improvement in latency and the degradation of coverage probability with the increase of spatial multiplexing gain at mmWave APs. Then we show the impact of spatial multiplexing on the throughput for the ultra-dense mmWave AP network.

cs.IT

The Geometry of Deep Networks: Power Diagram Subdivision

We study the geometry of deep (neural) networks (DNs) with piecewise affine and convex nonlinearities. The layers of such DNs have been shown to be {\em max-affine spline operators} (MASOs) that partition their input space and apply a region-dependent affine mapping to their input to produce their output. We demonstrate that each MASO layer's input space partitioning corresponds to a {\em power diagram} (an extension of the classical Voronoi tiling) with a number of regions that grows exponentially with respect to the number of units (neurons). We further show that a composition of MASO layers (e.g., the entire DN) produces a progressively subdivided power diagram and provide its analytical form. The subdivision process constrains the affine maps on the (exponentially many) power diagram regions to greatly reduce their complexity. For classification problems, we obtain a formula for a MASO DN's decision boundary in the input space plus a measure of its curvature that depends on the DN's nonlinearities, weights, and architecture. Numerous numerical experiments support and extend our theoretical results.

cs.LG

Mutual Information in Frequency and its Application to Measure Cross-Frequency Coupling in Epilepsy

We define a metric, mutual information in frequency (MI-in-frequency), to detect and quantify the statistical dependence between different frequency components in the data, referred to as cross-frequency coupling and apply it to electrophysiological recordings from the brain to infer cross-frequency coupling. The current metrics used to quantify the cross-frequency coupling in neuroscience cannot detect if two frequency components in non-Gaussian brain recordings are statistically independent or not. Our MI-in-frequency metric, based on Shannon's mutual information between the Cramer's representation of stochastic processes, overcomes this shortcoming and can detect statistical dependence in frequency between non-Gaussian signals. We then describe two data-driven estimators of MI-in-frequency: one based on kernel density estimation and the other based on the nearest neighbor algorithm and validate their performance on simulated data. We then use MI-in-frequency to estimate mutual information between two data streams that are dependent across time, without making any parametric model assumptions. Finally, we use the MI-in- frequency metric to investigate the cross-frequency coupling in seizure onset zone from electrocorticographic recordings during seizures. The inferred cross-frequency coupling characteristics are essential to optimize the spatial and spectral parameters of electrical stimulation based treatments of epilepsy.

q-bio.NC

On Integer-Forcing Precoding for the Gaussian MIMO Broadcast Channel

Integer-forcing (IF) precoding, also known as downlink IF, is a promising new approach for communication over multiple-input multiple-output (MIMO) broadcast channels. Inspired by the integer-forcing linear receiver for multiple-access channels, it generalizes linear precoding by inducing an effective channel matrix that is approximately integer, rather than approximately identity. Combined with lattice encoding and a pre-inversion of the channel matrix at the transmitter, the scheme has the potential to outperform any linear precoding scheme, despite enjoying similar low complexity. In this paper, a specific IF precoding scheme, called diagonally-scaled exact IF (DIF), is proposed and shown to achieve maximum spatial multiplexing gain. For the special case of two receivers, in the high SNR regime, an optimal choice of parameters is derived analytically, leading to an almost closed-form expression for the achievable sum rate. In particular, it is shown that the gap to the sum capacity is upper bounded by 0.27 bits for any channel realization. For general SNR, a regularized version of DIF (RDIF) is proposed. Numerical results for two receivers under Rayleigh fading show that RDIF can achieve performance superior to optimal linear precoding and very close to the sum capacity.

cs.IT

Data-Driven Estimation Of Mutual Information Between Dependent Data

We consider the problem of estimating mutual information between dependent data, an important problem in many science and engineering applications. We propose a data-driven, non-parametric estimator of mutual information in this paper. The main novelty of our solution lies in transforming the data to frequency domain to make the problem tractable. We define a novel metric--mutual information in frequency--to detect and quantify the dependence between two random processes across frequency using Cramér's spectral representation. Our solution calculates mutual information as a function of frequency to estimate the mutual information between the dependent data over time. We validate its performance on linear and nonlinear models. In addition, mutual information in frequency estimated as a part of our solution can also be used to infer cross-frequency coupling in the data.

cs.IT

Robust Unsupervised Transient Detection With Invariant Representation based on the Scattering Network

We present a sparse and invariant representation with low asymptotic complexity for robust unsupervised transient and onset zone detection in noisy environments. This unsupervised approach is based on wavelet transforms and leverages the scattering network from Mallat et al. by deriving frequency invariance. This frequency invariance is a key concept to enforce robust representations of transients in presence of possible frequency shifts and perturbations occurring in the original signal. Implementation details as well as complexity analysis are provided in addition of the theoretical framework and the invariance properties. In this work, our primary application consists of predicting the onset of seizure in epileptic patients from subdural recordings as well as detecting inter-ictal spikes.

stat.ML

Identifying Seizure Onset Zone from the Causal Connectivity Inferred Using Directed Information

In this paper, we developed a model-based and a data-driven estimator for directed information (DI) to infer the causal connectivity graph between electrocorticographic (ECoG) signals recorded from brain and to identify the seizure onset zone (SOZ) in epileptic patients. Directed information, an information theoretic quantity, is a general metric to infer causal connectivity between time-series and is not restricted to a particular class of models unlike the popular metrics based on Granger causality or transfer entropy. The proposed estimators are shown to be almost surely convergent. Causal connectivity between ECoG electrodes in five epileptic patients is inferred using the proposed DI estimators, after validating their performance on simulated data. We then proposed a model-based and a data-driven SOZ identification algorithm to identify SOZ from the causal connectivity inferred using model-based and data-driven DI estimators respectively. The data-driven SOZ identification outperforms the model-based SOZ identification algorithm when benchmarked against visual analysis by neurologist, the current clinical gold standard. The causal connectivity analysis presented here is the first step towards developing novel non-surgical treatments for epilepsy.

q-bio.NC

Low-Dimensional Shaping for High-Dimensional Lattice Codes

We propose two low-complexity lattice code constructions that have competitive coding and shaping gains. The first construction, named systematic Voronoi shaping, maps short blocks of integers to the dithered Voronoi integers, which are dithered integers that are uniformly distributed over the Voronoi region of a low-dimensional shaping lattice. Then, these dithered Voronoi integers are encoded using a high-dimensional lattice retaining the same shaping and coding gains of low and high-dimensional lattices. A drawback to this construction is that there is no isomorphism between the underlying message and the lattice code, preventing its use in applications such as compute-and- forward. Therefore we propose a second construction, called mixed nested lattice codes, in which a high-dimensional coding lattice is nested inside a concatenation of low-dimensional shaping lattices. This construction not only retains the same shaping/coding gains as first construction but also provides the desired algebraic structure. We numerically study these methods, for point-to-point channels as well as compute-and-forward using low-density lattice codes (LDLCs) as coding lattices and E8 and Barnes-Wall as shaping lattices. Numerical results indicate a shaping gain of up to 0.86 dB, compared to the state-of-the-art of 0.4 dB; furthermore, the proposed method has lower complexity than state-of-the-art approaches.

cs.IT