arXiv subjects

Ben Miller

Publications and source records attributed to Ben Miller.

4 recordsLinked to original sources

arXiv2026

Matrix group $\Lambda$-distributions

The $\Lambda$-distribution of a compact matrix group is an invariant in algebraic probability theory that was recently introduced to study zero distributions of function field $L$-functions. It is encoded by the $\sigma$-moment generating function, a generalization of the Molien series of classical invariant theory. In this work, we compute the $\sigma$-moment generating functions of finite matrix groups in many new cases. In particular, we compute the asymptotic $\Lambda$-distributions for the infinite families of Weyl reflection groups of types $B_n/C_n$ and $D_n$, complementing the previously known case of reflection groups of type $A_n$, i.e., symmetric groups. We also establish a general result relating the shapes of $\sigma$-moment generating functions to the distributions of associated classical random variables, explaining a previous ad hoc observation for independent Gaussians arising from traces of powers on compact classical groups.

math.RT↗

arXiv2026

Hermes: Large DEL Datasets Train Generalizable Protein-Ligand Binding Prediction Models

The quality and consistency of training data remain critical bottlenecks for protein-ligand binding prediction. Public affinity datasets, aggregated from thousands of labs and assay formats, introduce biases that limit model generalization and complicate evaluation. DNA-encoded chemical libraries (DELs) offer a potential solution: unified experimental protocols generating massive binding datasets across diverse chemical and protein target space. We present Hermes, a lightweight transformer trained exclusively on DEL data from screens against hundreds of protein targets, representing one of the largest and most protein-diverse DEL training sets applied to protein-ligand interaction (PLI) modeling to date. Despite never seeing traditional affinity measurements during training, Hermes generalizes to held-out targets, novel chemical scaffolds, and external benchmarks derived from public binding data and high-throughput screens. Our results demonstrate that DEL data alone captures transferable protein-ligand interaction representations, while Hermes' minimal architecture enables inference speeds suitable for large-scale virtual screening.

q-bio.BM↗

arXiv2019

Bridging the Gap Between Computational Photography and Visual Recognition

What is the current state-of-the-art for image restoration and enhancement applied to degraded images acquired under less than ideal circumstances? Can the application of such algorithms as a pre-processing step to improve image interpretability for manual analysis or automatic visual recognition to classify scene content? While there have been important advances in the area of computational photography to restore or enhance the visual quality of an image, the capabilities of such techniques have not always translated in a useful way to visual recognition tasks. Consequently, there is a pressing need for the development of algorithms that are designed for the joint problem of improving visual appearance and recognition, which will be an enabling factor for the deployment of visual recognition tools in many real-world scenarios. To address this, we introduce the UG^2 dataset as a large-scale benchmark composed of video imagery captured under challenging conditions, and two enhancement tasks designed to test algorithmic impact on visual quality and automatic object recognition. Furthermore, we propose a set of metrics to evaluate the joint improvement of such tasks as well as individual algorithmic advances, including a novel psychophysics-based evaluation regime for human assessment and a realistic set of quantitative measures for object recognition performance. We introduce six new algorithms for image restoration or enhancement, which were created as part of the IARPA sponsored UG^2 Challenge workshop held at CVPR 2018. Under the proposed evaluation regime, we present an in-depth analysis of these algorithms and a host of deep learning-based and classic baseline approaches. From the observed results, it is evident that we are in the early days of building a bridge between computational photography and visual recognition, leaving many opportunities for innovation in this area.

cs.CV↗

arXiv2015

Graphulo: Linear Algebra Graph Kernels for NoSQL Databases

Big data and the Internet of Things era continue to challenge computational systems. Several technology solutions such as NoSQL databases have been developed to deal with this challenge. In order to generate meaningful results from large datasets, analysts often use a graph representation which provides an intuitive way to work with the data. Graph vertices can represent users and events, and edges can represent the relationship between vertices. Graph algorithms are used to extract meaningful information from these very large graphs. At MIT, the Graphulo initiative is an effort to perform graph algorithms directly in NoSQL databases such as Apache Accumulo or SciDB, which have an inherently sparse data storage scheme. Sparse matrix operations have a history of efficient implementations and the Graph Basic Linear Algebra Subprogram (GraphBLAS) community has developed a set of key kernels that can be used to develop efficient linear algebra operations. However, in order to use the GraphBLAS kernels, it is important that common graph algorithms be recast using the linear algebra building blocks. In this article, we look at common classes of graph algorithms and recast them into linear algebra operations using the GraphBLAS building blocks.

cs.DS↗