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Ben Spycher

Publications and source records attributed to Ben Spycher.

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Easy Conditioning far beyond Gaussian

Multivariate Gaussian distributions enjoy Gaussian conditional distributions that makes conditioning easy: conditioning boils down to implementing analytical formulae for conditional means and covariances. For more general distributions, however, conditional distributions may not be available in analytical form and require demanding and approximate numerical approaches. Primarily motivatedby probabilistic imputation problems, we review and discuss families of multivariate distributions that do enjoy analytical conditioning, also providing a few counter-examples. Proving that trans-dimensional stability under conditioning extends to mixtures and transformations, we demonstrate that a broader class of multivariate distributions inherit easy conditioning properties. Building on this insight, we developed a generative method to estimate conditional distributions from data by first fitting a flexible joint distribution using copulas and then performing analytical conditioning in a latent space. In our applications, we specifically opt for Gaussian Mixture Copula Models (GMCM), comparing in turn various fitting strategies. Through simulations and real-world data experiments, we showcase the efficacy of our method in tasks involving conditional density estimation and data imputation. We also touch upon links to Gaussian process modelling and how stability by mixtures and transformations and mixtures carries over towards easy conditioning of non-Gaussian processes.

stat.ME

Discrete versus continuous domain models for disease mapping

The main goal of disease mapping is to estimate disease risk and identify high-risk areas. Such analyses are hampered by the limited geographical resolution of the available data. Typically the available data are counts per spatial unit and the common approach is the Besag--York--Molli{é} (BYM) model. When precise geocodes are available, it is more natural to use Log-Gaussian Cox processes (LGCPs). In a simulation study mimicking childhood leukaemia incidence using actual residential locations of all children in the canton of Zürich, Switzerland, we compare the ability of these models to recover risk surfaces and identify high-risk areas. We then apply both approaches to actual data on childhood leukaemia incidence in the canton of Zürich during 1985-2015. We found that LGCPs outperform BYM models in almost all scenarios considered. Our findings suggest that there are important gains to be made from the use of LGCPs in spatial epidemiology.

stat.AP