Searcharxiv⌕ Search

arXiv subjects

Benjamín Hernández

Publications and source records attributed to Benjamín Hernández.

2 recordsLinked to original sources

Planar AdS multi-NUT spacetimes and Kaluza-Klein multi-monopoles

In higher-dimensional Einstein-AdS gravity, it is well known that planar and static anti-de Sitter black holes can be endowed with multiple rotation parameters via a large-gauge transformation. However, a similar prescription fails when multiple NUT parameters are added, thereby obstructing the study of holographic properties with more than one NUT charge. To pave the way towards this direction, we construct explicit planar AdS spacetimes having multiple NUT parameters in two simple ways that allow one to circumvent the strong restrictions imposed by the vacuum field equations. First, motivated by momentum relaxation holographic models, we construct multi-NUT spaces in AdS with flat horizons by adding free scalar fields possessing an axionic profile. In our second approach, we build similar configurations in Einstein gravity with quadratic-curvature corrections. We end by presenting planar versions of the Kaluza-Klein monopole in AdS with different magnetic charges. As a byproduct, our strategy yields a simple way to generalize the Gross-Perry-Sorkin monopole to include the cosmological constant.

hep-th↗

Gold-standard of HER2 breast cancer biopsies using supervised learning based on multiple pathologist annotations

Breast cancer is one of the most common cancer in women around the world. For diagnosis, pathologists evaluate biomarkers such as HER2 protein using immunohistochemistry over tissue extracted by a biopsy. Through microscopic inspection, this assessment estimates the intensity and integrity of the membrane cells' staining and scores the sample as 0, 1+, 2+, or 3+: a subjective decision that depends on the interpretation of the pathologist. This paper presents the preliminary data analysis of the annotations of three pathologists over the same set of samples obtained using 20x magnification and including $1,252$ non-overlapping biopsy patches. We evaluate the intra- and inter-expert variability achieving substantial and moderate agreement, respectively, according to Fleiss' Kappa coefficient, as a previous stage towards a generation of a HER2 breast cancer biopsy gold-standard using supervised learning from multiple pathologist annotations.

eess.IV↗