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Benny Yong

Publications and source records attributed to Benny Yong.

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Combating New COVID-19 Variants in Indonesia: Is Accelerating Four-Dose Vaccinations Sufficient?

As new COVID-19 variants continue to emerge globally, we develop an SISI-type mathematical model to determine whether the transmission risks arising when such a new variant enters Indonesia can be mitigated by solely accelerating the country's ongoing four-dose vaccination programme. We begin by determining the model's basic reproduction number, as well as the model's equilibria and their stability. Subsequently, employing parameter values representing the country's situation as of March 20, 2023, we conduct a numerical sensitivity analysis in two simulated cases corresponding to two different levels of the new variant's transmission. The results show that, a satisfactory mitigation relying solely on vaccinations necessitates a drastic acceleration in the low-transmission case, and proves unachievable in the high-transmission case. Accordingly, we recommend that the acceleration of the ongoing four-dose vaccinations be carried out in conjunction with other intervention measures, such as improvements of the vaccine's efficacy and the disease's recovery rate.

math.DS

Codimension-Two Bifurcations of an SIR-Type Model for COVID-19 and Their Epidemiological Implications

We study the codimension-two bifurcations exhibited by a recently-developed SIR-type mathematical model for the spread of COVID-19, as its two main parameters -- the susceptible individuals' cautiousness level and the hospitals' bed-occupancy rate -- vary over their domains. We use AUTO to generate the model's bifurcation diagrams near the relevant bifurcation points: two Bogdanov-Takens points and two generalised Hopf points, as well as a number of phase portraits describing the model's orbital behaviours for various pairs of parameter values near each bifurcation point. The analysis shows that, when a backward bifurcation occurs at the basic reproduction threshold, the transition of the model's asymptotic behaviour from endemic to disease-free takes place via an unexpectedly complex sequence of topological changes, involving the births and disappearances of not only equilibria but also limit cycles and homoclinic orbits. Epidemiologically, the analysis confirms the importance of a proper control of the values of the aforementioned parameters for a successful eradication of COVID-19. We recommend a number of strategies by which such a control may be achieved.

math.DS

Mathematical Analysis of an Epidemic Model for COVID-19: How Important Is the People's Cautiousness Level for Eradication?

We construct an SIR-type model for COVID-19, incorporating as a parameter the susceptible individuals' cautiousness level. We determine the model's basic reproduction number, study the stability of the equilibria analytically, and perform a sensitivity analysis to confirm the significance of the cautiousness level. Fixing specific values for all other parameters, we study numerically the model's dynamics as the cautiousness level varies, revealing backward transcritical, Hopf, and saddle-node bifurcations of equilibria, as well as homoclinic and fold bifurcations of limit cycles with the aid of AUTO. Considering some key events affecting the pandemic in Indonesia, we design a scenario in which the cautiousness level varies over time, and show that the model exhibits a hysteresis, whereby, a slight cautiousness decrease could bring a disease-free state to endemic, and this is reversible only by a drastic cautiousness increase, thereby mathematically justifying the importance of a high cautiousness level for resolving the pandemic.

math.DS

From Pandemic to a New Normal: Strategies to Optimise Governmental Interventions in Indonesia Based on an SVEIQHR-Type Mathematical Model

There are five different forms of intervention presently realised by the Indonesian government in an effort to end the COVID-19 pandemic: vaccinations, social restrictions, tracings, testings, and treatments. In this paper, we construct an SVEIQHR-type mathematical model for the disease's spread in the country, which incorporates as parameters the rates of the above interventions, as well as the vaccine's efficacy. We determine the model's equilibria and basic reproduction number. Using the model, we formulate strategies by which the interventions should be realised in order to optimise their impact. The results show that, in a disease-free state, when the number of new cases rises, the best strategy is to implement social restrictions, whereas in an endemic state, if a near-lockdown policy is undesirable, carrying out vaccinations is the best strategy; however, efforts should be aimed not primarily towards increasing the vaccination rate, but towards the use of high-efficacy vaccines.

math.DS

A Design of Governmental Policies for the Eradication of COVID-19 in Jakarta Using an SIR-Type Mathematical Model

Using a discretised version of our recently-developed SIR-type mathematical model for the spread of COVID-19, we construct a design of governmental policies for the eradication of the disease in the province of DKI Jakarta, Indonesia, taking as a basis the actual data of mid-2021. The design takes the form of a precise, quantitative method to determine the appropriate level(s) of restrictions on community activities (PPKM) which should be enforced in the province on any given day, based on the current values of the disease's effective reproduction number and the hospitals' bed-occupancy rate.

math.DS