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Bhargav Karamched

Publications and source records attributed to Bhargav Karamched.

4 recordsLinked to original sources

Observability of complex systems via conserved quantities

Many systems in biology, physics, and engineering are modeled by nonlinear dynamical systems where the states are usually unknown and only a subset of the state variables can be physically measured. Can we understand the full system from what we measure? In the mathematics literature, this question is framed as the observability problem. It has to do with recovering information about the state variables from the observed states (the measurements). In this paper, we relate the observability problem to another structural feature of many models relevant in the physical and biological sciences: the conserved quantity. For models based on systems of differential equations, conserved quantities offer desirable properties such as dimension reduction which simplifies model analysis. Here, we use differential embeddings to show that conserved quantities involving a set of special variables provide more flexibility in what can be measured to address the observability problem for systems of interest in biology. Specifically, we provide conditions under which a collection of conserved quantities make the system observable. We apply our methods to provide alternate measurable variables in models where conserved quantities have been used for model analysis historically in biological contexts.

math.DS

Delay-Induced Uncertainty for a Paradigmatic Glucose-Insulin Model

Medical practice in the intensive care unit is based on the supposition that physiological systems such as the human glucose-insulin system are predictable. We demonstrate that delay within the glucose-insulin system can induce sustained temporal chaos, rendering the system unpredictable. Specifically, we exhibit such chaos for the Ultradian glucose-insulin model. This well-validated, finite-dimensional model represents feedback delay as a three-stage filter. Using the theory of rank one maps from smooth dynamical systems, we precisely explain the nature of the resulting delay-induced uncertainty (DIU). We develop a recipe one may use to diagnose DIU in a general oscillatory dynamical system. For infinite-dimensional delay systems, no analog of the theory of rank one maps exists. Nevertheless, we show that the geometric principles encoded in our DIU recipe apply to such systems by exhibiting sustained temporal chaos for a linear shear flow. Our results are potentially broadly applicable because delay is ubiquitous throughout mathematical physiology.

math.DS

Diversity Improves Speed and Accuracy in Social Networks

How does temporally structured private and social information shape collective decisions? To address this question we consider a network of rational agents who independently accumulate private evidence that triggers a decision upon reaching a threshold. When seen by the whole network, the first agent's choice initiates a wave of new decisions; later decisions have less impact. In heterogeneous networks, first decisions are made quickly by impulsive individuals who need little evidence to make a choice, but, even when wrong, can reveal the correct options to nearly everyone else. We conclude that groups comprised of diverse individuals can make more efficient decisions than homogenous ones.

physics.soc-ph

Bayesian Evidence Accumulation on Social Networks

To make decisions we are guided by the evidence we collect, as well as the opinions of friends and neighbors. How do we integrate our private beliefs with information we obtain from our social network? To understand the strategies humans use to do so it is useful to compare them to observers that optimally integrate all evidence. Here we derive network models of rational (Bayes optimal) agents who accumulate private measurements and observe decisions of their neighbors to make an irreversible choice between two options. The resulting information exchange dynamics has interesting properties: When one option is preferred, the absence of a decision can be increasingly informative over time. In recurrent networks an absence of a decision can lead to a sequence of belief updates akin to those in the literature on common knowledge. Information obtained from observing repeated non-decisions is independent of realization, unless the private information of agents is redundant. On the other hand, in larger networks a single decision can trigger a cascade of agreements and disagreements that depend on the private information agents have gathered. Our approach provides a bridge between social decision making models in the economics literature, which largely ignore the temporal dynamics of decisions, and the single-observer evidence accumulator models used widely in neuroscience and psychology.

physics.soc-ph