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Biao Li

Publications and source records attributed to Biao Li.

At least 19 recordsLinked to original sources

A Brief History of Digital Twin Technology

Emerging from NASA's spacecraft simulations in the 1960s, digital twin technology has advanced through industrial adoption to spark a healthcare transformation. A digital twin is a dynamic, data-driven virtual counterpart of a physical system, continuously updated through real-time data streams and capable of bidirectional interaction. In medicine, digital twin integrates imaging, biosensors, and computational models to generate patient-specific simulations that support diagnosis, treatment planning, and drug development. Representative applications include cardiac digital twin for predicting arrhythmia treatment outcomes, oncology digital twin for tracking tumor progression and optimizing radiotherapy, and pharmacological digital twin for accelerating drug discovery. Despite rapid progress, major challenges, including interoperability, data privacy, and model fidelity, continue to limit widespread clinical integration. Emerging solutions such as explainable AI, federated learning, and harmonized regulatory frameworks offer promising pathways forward. Looking ahead, advances in multi-organ digital twin, genomics integration, and ethical governance will be essential to ensure that digital twin shifts healthcare from reactive treatment to predictive, preventive, and truly personalized medicine.

cs.AI

Clarifying Before Reasoning: A Coq Prover with Structural Context

In this work, we investigate whether improving task clarity can enhance reasoning ability of large language models, focusing on theorem proving in Coq. We introduce a concept-level metric to evaluate task clarity and show that adding structured semantic context to the standard input used by modern LLMs, leads to a 1.85$\times$ improvement in clarity score (44.5\%~$\rightarrow$~82.3\%). Using the general-purpose model \texttt{DeepSeek-V3}, our approach leads to a 2.1$\times$ improvement in proof success (21.8\%~$\rightarrow$~45.8\%) and outperforms the previous state-of-the-art \texttt{Graph2Tac} (33.2\%). We evaluate this on 1,386 theorems randomly sampled from 15 standard Coq packages, following the same evaluation protocol as \texttt{Graph2Tac}. Furthermore, fine-tuning smaller models on our structured data can achieve even higher performance (48.6\%). Our method uses selective concept unfolding to enrich task descriptions, and employs a Planner--Executor architecture. These findings highlight the value of structured task representations in bridging the gap between understanding and reasoning.

cs.AI

A Point-Hyperplane Geometry Method for Operational Security Region of Renewable Energy Generation in Power Systems

The rapid growth of renewable energy generation challenges the secure operation of power systems. It becomes crucial to quantify the critical security boundaries and hosting capability of renewable generation at the system operation level. This paper proposes a novel point-hyperplane geometry (PHG) method to accurately obtain the geometric expression of the operational security region of renewable energy generation for power systems. Firstly, the geometric expression of the operational security region is defined as a polytope of boundary hyperplanes in the form of inequalities satisfying the system operation constraints. Then, an orthogonal basis generation method is proposed to solve a single boundary hyperplane of the polytope based on intersecting and orthogonal geometric principles. Next, a point-hyperplane iteration algorithm is developed to progressively obtain the overall geometric polytope of the operational security region of renewable energy generation in power systems. Besides, the flexible performance trade-off can be achieved by modifying the proposed maximum tolerated angle between adjacent hyperplanes. Finally, comprehensive case studies verify the effectiveness and superiority of the PHG method.

eess.SY

Fed-NDIF: A Noise-Embedded Federated Diffusion Model For Low-Count Whole-Body PET Denoising

Low-count positron emission tomography (LCPET) imaging can reduce patients' exposure to radiation but often suffers from increased image noise and reduced lesion detectability, necessitating effective denoising techniques. Diffusion models have shown promise in LCPET denoising for recovering degraded image quality. However, training such models requires large and diverse datasets, which are challenging to obtain in the medical domain. To address data scarcity and privacy concerns, we combine diffusion models with federated learning -- a decentralized training approach where models are trained individually at different sites, and their parameters are aggregated on a central server over multiple iterations. The variation in scanner types and image noise levels within and across institutions poses additional challenges for federated learning in LCPET denoising. In this study, we propose a novel noise-embedded federated learning diffusion model (Fed-NDIF) to address these challenges, leveraging a multicenter dataset and varying count levels. Our approach incorporates liver normalized standard deviation (NSTD) noise embedding into a 2.5D diffusion model and utilizes the Federated Averaging (FedAvg) algorithm to aggregate locally trained models into a global model, which is subsequently fine-tuned on local datasets to optimize performance and obtain personalized models. Extensive validation on datasets from the University of Bern, Ruijin Hospital in Shanghai, and Yale-New Haven Hospital demonstrates the superior performance of our method in enhancing image quality and improving lesion quantification. The Fed-NDIF model shows significant improvements in PSNR, SSIM, and NMSE of the entire 3D volume, as well as enhanced lesion detectability and quantification, compared to local diffusion models and federated UNet-based models.

eess.IV

An Interpretable ML-based Model for Predicting p-y Curves of Monopile Foundations in Sand

Predicting the lateral pile response is challenging due to the complexity of pile-soil interactions. Machine learning (ML) techniques have gained considerable attention for their effectiveness in non-linear analysis and prediction. This study develops an interpretable ML-based model for predicting p-y curves of monopile foundations. An XGBoost model was trained using a database compiled from existing research. The results demonstrate that the model achieves superior predictive accuracy. Shapley Additive Explanations (SHAP) was employed to enhance interpretability. The SHAP value distributions for each variable demonstrate strong alignment with established theoretical knowledge on factors affecting the lateral response of pile foundations.

cs.LG

Bi-directional Mapping of Morphology Metrics and 3D City Blocks for Enhanced Characterization and Generation of Urban Form

Urban morphology, examining city spatial configurations, links urban design to sustainability. Morphology metrics play a fundamental role in performance-driven computational urban design (CUD) which integrates urban form generation, performance evaluation and optimization. However, a critical gap remains between performance evaluation and complex urban form generation, caused by the disconnection between morphology metrics and urban form, particularly in metric-to-form workflows. It prevents the application of optimized metrics to generate improved urban form with enhanced urban performance. Formulating morphology metrics that not only effectively characterize complex urban forms but also enable the reconstruction of diverse forms is of significant importance. This paper highlights the importance of establishing a bi-directional mapping between morphology metrics and complex urban form to enable the integration of urban form generation with performance evaluation. We present an approach that can 1) formulate morphology metrics to both characterize urban forms and in reverse, retrieve diverse similar 3D urban forms, and 2) evaluate the effectiveness of morphology metrics in representing 3D urban form characteristics of blocks by comparison. We demonstrate the methodology with 3D urban models of New York City, covering 14,248 blocks. We use neural networks and information retrieval for morphology metric encoding, urban form clustering and morphology metric evaluation. We identified an effective set of morphology metrics for characterizing block-scale urban forms through comparison. The proposed methodology tightly couples complex urban forms with morphology metrics, hence it can enable a seamless and bidirectional relationship between urban form generation and optimization in performance-driven urban design towards sustainable urban design and planning.

cs.CE

Complexity boosted adaptive training for better low resource ASR performance

During the entire training process of the ASR model, the intensity of data augmentation and the approach of calculating training loss are applied in a regulated manner based on preset parameters. For example, SpecAugment employs a predefined strength of augmentation to mask parts of the time-frequency domain spectrum. Similarly, in CTC-based multi-layer models, the loss is generally determined based on the output of the encoder's final layer during the training process. However, ignoring dynamic characteristics may suboptimally train models. To address the issue, we present a two-stage training method, known as complexity-boosted adaptive (CBA) training. It involves making dynamic adjustments to data augmentation strategies and CTC loss propagation based on the complexity of the training samples. In the first stage, we train the model with intermediate-CTC-based regularization and data augmentation without any adaptive policy. In the second stage, we propose a novel adaptive policy, called MinMax-IBF, which calculates the complexity of samples. We combine the MinMax-IBF policy to data augmentation and intermediate CTC loss regularization to continue training. The proposed CBA training approach shows considerable improvements, up to 13.4% and 14.1% relative reduction in WER on the LibriSpeech 100h test-clean and test-other dataset and also up to 6.3% relative reduction on AISHELL-1 test set, over the Conformer architecture in Wenet.

cs.SD

Sample adaptive data augmentation with progressive scheduling

Data augmentation is a widely adopted technique utilized to improve the robustness of automatic speech recognition (ASR). Employing a fixed data augmentation strategy for all training data is a common practice. However, it is important to note that there can be variations in factors such as background noise, speech rate, etc. among different samples within a single training batch. By using a fixed augmentation strategy, there is a risk that the model may reach a suboptimal state. In addition to the risks of employing a fixed augmentation strategy, the model's capabilities may differ across various training stages. To address these issues, this paper proposes the method of sample-adaptive data augmentation with progressive scheduling(PS-SapAug). The proposed method applies dynamic data augmentation in a two-stage training approach. It employs hybrid normalization to compute sample-specific augmentation parameters based on each sample's loss. Additionally, the probability of augmentation gradually increases throughout the training progression. Our method is evaluated on popular ASR benchmark datasets, including Aishell-1 and Librispeech-100h, achieving up to 8.13% WER reduction on LibriSpeech-100h test-clean, 6.23% on test-other, and 5.26% on AISHELL-1 test set, which demonstrate the efficacy of our approach enhancing performance and minimizing errors.

cs.SD

Lighten CARAFE: Dynamic Lightweight Upsampling with Guided Reassemble Kernels

As a fundamental operation in modern machine vision models, feature upsampling has been widely used and investigated in the literatures. An ideal upsampling operation should be lightweight, with low computational complexity. That is, it can not only improve the overall performance but also not affect the model complexity. Content-aware Reassembly of Features (CARAFE) is a well-designed learnable operation to achieve feature upsampling. Albeit encouraging performance achieved, this method requires generating large-scale kernels, which brings a mass of extra redundant parameters, and inherently has limited scalability. To this end, we propose a lightweight upsampling operation, termed Dynamic Lightweight Upsampling (DLU) in this paper. In particular, it first constructs a small-scale source kernel space, and then samples the large-scale kernels from the kernel space by introducing learnable guidance offsets, hence avoiding introducing a large collection of trainable parameters in upsampling. Experiments on several mainstream vision tasks show that our DLU achieves comparable and even better performance to the original CARAFE, but with much lower complexity, e.g., DLU requires 91% fewer parameters and at least 63% fewer FLOPs (Floating Point Operations) than CARAFE in the case of 16x upsampling, but outperforms the CARAFE by 0.3% mAP in object detection. Code is available at https://github.com/Fu0511/Dynamic-Lightweight-Upsampling.

cs.CV

Dose-aware Diffusion Model for 3D PET Image Denoising: Multi-institutional Validation with Reader Study and Real Low-dose Data

Reducing scan times, radiation dose, and enhancing image quality for lower-performance scanners, are critical in low-dose PET imaging. Deep learning techniques have been investigated for PET image denoising. However, existing models have often resulted in compromised image quality when achieving low-count/low-dose PET and have limited generalizability to different image noise-levels, acquisition protocols, and patient populations. Recently, diffusion models have emerged as the new state-of-the-art generative model to generate high-quality samples and have demonstrated strong potential for medical imaging tasks. However, for low-dose PET imaging, existing diffusion models failed to generate consistent 3D reconstructions, unable to generalize across varying noise-levels, often produced visually-appealing but distorted image details, and produced images with biased tracer uptake. Here, we develop DDPET-3D, a dose-aware diffusion model for 3D low-dose PET imaging to address these challenges. Collected from 4 medical centers globally with different scanners and clinical protocols, we evaluated the proposed model using a total of 9,783 18F-FDG studies with low-dose levels ranging from 1% to 50%. With a cross-center, cross-scanner validation, the proposed DDPET-3D demonstrated its potential to generalize to different low-dose levels, different scanners, and different clinical protocols. As confirmed with reader studies performed by board-certified nuclear medicine physicians, experienced readers judged the images to be similar or superior to the full-dose images and previous DL baselines based on qualitative visual impression. Lesion-level quantitative accuracy was evaluated using a Monte Carlo simulation study and a lesion segmentation network. The presented results show the potential to achieve low-dose PET while maintaining image quality. Real low-dose scans was also included for evaluation.

eess.IV

LeqMod: Adaptable Lesion-Quantification-Consistent Modulation for Deep Learning Low-Count PET Image Denoising

Deep learning-based positron emission tomography (PET) image denoising offers the potential to reduce radiation exposure and scanning time by transforming low-count images into high-count equivalents. However, existing methods typically blur crucial details, leading to inaccurate lesion quantification. This paper proposes a lesion-perceived and quantification-consistent modulation (LeqMod) strategy for enhanced PET image denoising, via employing downstream lesion quantification analysis as auxiliary tools. The LeqMod is a plug-and-play design adaptable to a wide range of model architectures, modulating the sampling and optimization procedures of model training without adding any computational burden to the inference phase. Specifically, the LeqMod consists of two components, the lesion-perceived modulation (LeMod) and the multiscale quantification-consistent modulation (QuMod). The LeMod enhances lesion contrast and visibility by allocating higher sampling weights and stricter loss criteria to lesion-present samples determined by an auxiliary segmentation network than lesion-absent ones. The QuMod further emphasizes quantification accuracy for both the mean and maximum standardized uptake value (SUVmean and SUVmax) across multiscale sub-regions throughout the entire image, thereby reducing biases of denoised results relative to high-count references. Experiments conducted on large PET datasets from multiple centers and vendors, and varying noise levels demonstrated the LeqMod efficacy across various denoising frameworks. Compared to frameworks without LeqMod, the integration of LeqMod reduces the lesion SUVmax bias by 5.92% on average and increases the peak signal-to-noise ratio (PSNR) by 0.36 on average, when denoising images across participating sites.

eess.IV

Simultaneous Localization and Recognition of Subwavelength Non-Cooperative Entities Based on SISO Time Reversal and Neural Networks

The simultaneous localization and recognition of subwavelength non-cooperative entities within complex multi-scattering environments using a simplified system continues to pose a substantial challenge. This letter addresses this challenge by synergistically integrating time reversal time-frequency phase prints (TRTFPPs) and neural networks. Initially, a time reversal (TR) single-input single-output (SISO) framework is employed to generate TRTFPPs. To enhance the models' adaptability, particularly in the presence of noise, data augmentation techniques are applied. Subsequently, neural networks are employed to comprehend the TRTFPPs. Specifically, a cascaded neural network structure is embraced, encompassing both a recognition neural network and distinct neural networks for localizing different entities. Through the devised approach, two types of subwavelength entities are successfully identified and precisely localized through numerical simulations and experimental verification in laboratory environment. The proposed methodology holds applicability across various electromagnetic systems, including but not limited to detection, imaging, human-computer interaction, and the Internet of Things (IoT).

physics.app-ph

Discrete Conditional Diffusion for Reranking in Recommendation

Reranking plays a crucial role in modern multi-stage recommender systems by rearranging the initial ranking list to model interplay between items. Considering the inherent challenges of reranking such as combinatorial searching space, some previous studies have adopted the evaluator-generator paradigm, with a generator producing feasible sequences and a evaluator selecting the best one based on estimated listwise utility. Inspired by the remarkable success of diffusion generative models, this paper explores the potential of diffusion models for generating high-quality sequences in reranking. However, we argue that it is nontrivial to take diffusion models as the generator in the context of recommendation. Firstly, diffusion models primarily operate in continuous data space, differing from the discrete data space of item permutations. Secondly, the recommendation task is different from conventional generation tasks as the purpose of recommender systems is to fulfill user interests. Lastly, real-life recommender systems require efficiency, posing challenges for the inference of diffusion models. To overcome these challenges, we propose a novel Discrete Conditional Diffusion Reranking (DCDR) framework for recommendation. DCDR extends traditional diffusion models by introducing a discrete forward process with tractable posteriors, which adds noise to item sequences through step-wise discrete operations (e.g., swapping). Additionally, DCDR incorporates a conditional reverse process that generates item sequences conditioned on expected user responses. Extensive offline experiments conducted on public datasets demonstrate that DCDR outperforms state-of-the-art reranking methods. Furthermore, DCDR has been deployed in a real-world video app with over 300 million daily active users, significantly enhancing online recommendation quality.

cs.IR

Measuring Item Global Residual Value for Fair Recommendation

In the era of information explosion, numerous items emerge every day, especially in feed scenarios. Due to the limited system display slots and user browsing attention, various recommendation systems are designed not only to satisfy users' personalized information needs but also to allocate items' exposure. However, recent recommendation studies mainly focus on modeling user preferences to present satisfying results and maximize user interactions, while paying little attention to developing item-side fair exposure mechanisms for rational information delivery. This may lead to serious resource allocation problems on the item side, such as the Snowball Effect. Furthermore, unfair exposure mechanisms may hurt recommendation performance. In this paper, we call for a shift of attention from modeling user preferences to developing fair exposure mechanisms for items. We first conduct empirical analyses of feed scenarios to explore exposure problems between items with distinct uploaded times. This points out that unfair exposure caused by the time factor may be the major cause of the Snowball Effect. Then, we propose to explicitly model item-level customized timeliness distribution, Global Residual Value (GRV), for fair resource allocation. This GRV module is introduced into recommendations with the designed Timeliness-aware Fair Recommendation Framework (TaFR). Extensive experiments on two datasets demonstrate that TaFR achieves consistent improvements with various backbone recommendation models. By modeling item-side customized Global Residual Value, we achieve a fairer distribution of resources and, at the same time, improve recommendation performance.

cs.IR

Alleviating Matthew Effect of Offline Reinforcement Learning in Interactive Recommendation

Offline reinforcement learning (RL), a technology that offline learns a policy from logged data without the need to interact with online environments, has become a favorable choice in decision-making processes like interactive recommendation. Offline RL faces the value overestimation problem. To address it, existing methods employ conservatism, e.g., by constraining the learned policy to be close to behavior policies or punishing the rarely visited state-action pairs. However, when applying such offline RL to recommendation, it will cause a severe Matthew effect, i.e., the rich get richer and the poor get poorer, by promoting popular items or categories while suppressing the less popular ones. It is a notorious issue that needs to be addressed in practical recommender systems. In this paper, we aim to alleviate the Matthew effect in offline RL-based recommendation. Through theoretical analyses, we find that the conservatism of existing methods fails in pursuing users' long-term satisfaction. It inspires us to add a penalty term to relax the pessimism on states with high entropy of the logging policy and indirectly penalizes actions leading to less diverse states. This leads to the main technical contribution of the work: Debiased model-based Offline RL (DORL) method. Experiments show that DORL not only captures user interests well but also alleviates the Matthew effect. The implementation is available via https://github.com/chongminggao/DORL-codes.

cs.IR

Tree based Progressive Regression Model for Watch-Time Prediction in Short-video Recommendation

An accurate prediction of watch time has been of vital importance to enhance user engagement in video recommender systems. To achieve this, there are four properties that a watch time prediction framework should satisfy: first, despite its continuous value, watch time is also an ordinal variable and the relative ordering between its values reflects the differences in user preferences. Therefore the ordinal relations should be reflected in watch time predictions. Second, the conditional dependence between the video-watching behaviors should be captured in the model. For instance, one has to watch half of the video before he/she finishes watching the whole video. Third, modeling watch time with a point estimation ignores the fact that models might give results with high uncertainty and this could cause bad cases in recommender systems. Therefore the framework should be aware of prediction uncertainty. Forth, the real-life recommender systems suffer from severe bias amplifications thus an estimation without bias amplification is expected. Therefore we propose TPM for watch time prediction. Specifically, the ordinal ranks of watch time are introduced into TPM and the problem is decomposed into a series of conditional dependent classification tasks which are organized into a tree structure. The expectation of watch time can be generated by traversing the tree and the variance of watch time predictions is explicitly introduced into the objective function as a measurement for uncertainty. Moreover, we illustrate that backdoor adjustment can be seamlessly incorporated into TPM, which alleviates bias amplifications. Extensive offline evaluations have been conducted in public datasets and TPM have been deployed in a real-world video app Kuaishou with over 300 million DAUs. The results indicate that TPM outperforms state-of-the-art approaches and indeed improves video consumption significantly.

cs.IR

Adaptive Contextual Biasing for Transducer Based Streaming Speech Recognition

By incorporating additional contextual information, deep biasing methods have emerged as a promising solution for speech recognition of personalized words. However, for real-world voice assistants, always biasing on such personalized words with high prediction scores can significantly degrade the performance of recognizing common words. To address this issue, we propose an adaptive contextual biasing method based on Context-Aware Transformer Transducer (CATT) that utilizes the biased encoder and predictor embeddings to perform streaming prediction of contextual phrase occurrences. Such prediction is then used to dynamically switch the bias list on and off, enabling the model to adapt to both personalized and common scenarios. Experiments on Librispeech and internal voice assistant datasets show that our approach can achieve up to 6.7% and 20.7% relative reduction in WER and CER compared to the baseline respectively, mitigating up to 96.7% and 84.9% of the relative WER and CER increase for common cases. Furthermore, our approach has a minimal performance impact in personalized scenarios while maintaining a streaming inference pipeline with negligible RTF increase.

cs.SD

FedFTN: Personalized Federated Learning with Deep Feature Transformation Network for Multi-institutional Low-count PET Denoising

Low-count PET is an efficient way to reduce radiation exposure and acquisition time, but the reconstructed images often suffer from low signal-to-noise ratio (SNR), thus affecting diagnosis and other downstream tasks. Recent advances in deep learning have shown great potential in improving low-count PET image quality, but acquiring a large, centralized, and diverse dataset from multiple institutions for training a robust model is difficult due to privacy and security concerns of patient data. Moreover, low-count PET data at different institutions may have different data distribution, thus requiring personalized models. While previous federated learning (FL) algorithms enable multi-institution collaborative training without the need of aggregating local data, addressing the large domain shift in the application of multi-institutional low-count PET denoising remains a challenge and is still highly under-explored. In this work, we propose FedFTN, a personalized federated learning strategy that addresses these challenges. FedFTN uses a local deep feature transformation network (FTN) to modulate the feature outputs of a globally shared denoising network, enabling personalized low-count PET denoising for each institution. During the federated learning process, only the denoising network's weights are communicated and aggregated, while the FTN remains at the local institutions for feature transformation. We evaluated our method using a large-scale dataset of multi-institutional low-count PET imaging data from three medical centers located across three continents, and showed that FedFTN provides high-quality low-count PET images, outperforming previous baseline FL reconstruction methods across all low-count levels at all three institutions.

eess.IV