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Bing Yao

Publications and source records attributed to Bing Yao.

At least 19 recordsLinked to original sources

P-K-GCN: Physics-augmented Koopman-enhanced Graph Convolutional Network for Deep Spatiotemporal Super-resolution

High-fidelity simulation of spatiotemporal dynamics is computationally prohibitive, necessitating efficient super-resolution techniques to reconstruct high-resolution data from coarse-grained inputs. Traditional data-driven methods often lack physical constraints, and simple physics-informed learning struggles with irregular spatial geometries and intricately evolving temporal dynamics. To tackle these challenges, we propose a Physics-augmented Koopman-enhanced Graph Convolutional Network (P-K-GCN) for spatiotemporal super-resolution on irregular geometries. Specifically, a continuous spline-based GCN is first designed to extract spatial dependencies directly from coarse graph, and Koopman operator theory is incorporated to project the nonlinear dynamics into a compact latent space where temporal progression is linearized. Second, we augment the optimization objective with a physics-based loss to force the data-driven reconstructions to adhere to physical laws for improving predictive fidelity and robustness. Finally, we provide a rigorous theoretical analysis, establishing that the physics augmentation and Koopman regularization mathematically guarantees a reduction in super-resolution error by diminishing Rademacher complexity and tightening generalization bounds. We evaluate our framework on reconstructing spatially high-resolution cardiac electrodynamics across a 3D heart geometry from sparse low-resolution measurements. Numerical experiments demonstrate that our method achieves superior accuracy compared to baseline models.

cs.LG

Multi-Modal Machine Learning for Breast Cancer Recurrence Prediction

Breast cancer recurrence, a leading cause of long-term mortality among survivors, requires timely and accurate risk assessment to guide follow-up care and treatment planning. Traditional predictive models, often limited to either structured or unstructured data alone, struggle to capture the full clinical context. This study examines the impact of integrating multi-modal clinical data, including treatment records, pathology reports, and clinician notes, on recurrence prediction. By integrating a rule-based regular expression extraction mechanism with a rigorous precedence-based conflict reconciliation strategy, our approach effectively recovers definitive tumor characteristics from free-text pathology narratives to augment structured records. We also benchmark performance against commonly used feature sets from prior breast cancer studies to assess the added value of multi-modal integration. Single-source and multi-modal inputs are evaluated across a range of machine learning models. Results show that multi-modal integration consistently improves predictive accuracy compared to single-modal methods.

cs.LG

Multi-Task LLM with LoRA Fine-Tuning for Automated Cancer Staging and Biomarker Extraction

Pathology reports serve as the definitive record for breast cancer staging, yet their unstructured format impedes large-scale data curation. While Large Language Models (LLMs) offer semantic reasoning, their deployment is often limited by high computational costs and hallucination risks. This study introduces a parameter-efficient, multi-task framework for automating the extraction of Tumor-Node-Metastasis (TNM) staging, histologic grade, and biomarkers. We fine-tune a Llama-3-8B-Instruct encoder using Low-Rank Adaptation (LoRA) on a curated, expert-verified dataset of 10,677 reports. Unlike generative approaches, our architecture utilizes parallel classification heads to enforce consistent schema adherence. Experimental results demonstrate that the model achieves a Macro F1 score of 0.976, successfully resolving complex contextual ambiguities and heterogeneous reporting formats that challenge traditional extraction methods including rule-based natural language processing (NLP) pipelines, zero-shot LLMs, and single-task LLM baselines. The proposed adapter-efficient, multi-task architecture enables reliable, scalable pathology-derived cancer staging and biomarker profiling, with the potential to enhance clinical decision support and accelerate data-driven oncology research.

cs.LG

Physics-augmented Multi-task Gaussian Process for Modeling Spatiotemporal Dynamics

Recent advances in sensing and imaging technologies have enabled the collection of high-dimensional spatiotemporal data across complex geometric domains. However, effective modeling of such data remains challenging due to irregular spatial structures, rapid temporal dynamics, and the need to jointly predict multiple interrelated physical variables. This paper presents a physics-augmented multi-task Gaussian Process (P-M-GP) framework tailored for spatiotemporal dynamic systems. Specifically, we develop a geometry-aware, multi-task Gaussian Process (M-GP) model to effectively capture intrinsic spatiotemporal structure and inter-task dependencies. To further enhance the model fidelity and robustness, we incorporate governing physical laws through a physics-based regularization scheme, thereby constraining predictions to be consistent with governing dynamical principles. We validate the proposed P-M-GP framework on a 3D cardiac electrodynamics modeling task. Numerical experiments demonstrate that our method significantly improves prediction accuracy over existing methods by effectively incorporating domain-specific physical constraints and geometric prior.

cs.LG

Transformer with Koopman-Enhanced Graph Convolutional Network for Spatiotemporal Dynamics Forecasting

Spatiotemporal dynamics forecasting is inherently challenging, particularly in systems defined over irregular geometric domains, due to the need to jointly capture complex spatial correlations and nonlinear temporal dynamics. To tackle these challenges, we propose TK-GCN, a two-stage framework that integrates geometry-aware spatial encoding with long-range temporal modeling. In the first stage, a Koopman-enhanced Graph Convolutional Network (K-GCN) is developed to embed the high-dimensional dynamics distributed on spatially irregular domains into a latent space where the evolution of system states is approximately linear. By leveraging Koopman operator theory, this stage enhances the temporal consistency during the latent learning. In the second stage, a Transformer module is employed to model the temporal progression within the Koopman-encoded latent space. Through the self-attention mechanism, the Transformer captures long-range temporal dependencies, enabling accurate forecasting over extended horizons. We evaluate TK-GCN in spatiotemporal cardiac dynamics forecasting and benchmark its performance against several state-of-the-art baselines. Experimental results and ablation studies show that TK-GCN consistently delivers superior predictive accuracy across a range of forecast horizons, demonstrating its capability to effectively model complex spatial structures and nonlinear temporal dynamics.

cs.LG

Geometry-aware Active Learning of Spatiotemporal Dynamic Systems

Rapid developments in advanced sensing and imaging have significantly enhanced information visibility, opening opportunities for predictive modeling of complex dynamic systems. However, sensing signals acquired from such complex systems are often distributed across 3D geometries and rapidly evolving over time, posing significant challenges in spatiotemporal predictive modeling. This paper proposes a geometry-aware active learning framework for modeling spatiotemporal dynamic systems. Specifically, we propose a geometry-aware spatiotemporal Gaussian Process (G-ST-GP) to effectively integrate the temporal correlations and geometric manifold features for reliable prediction of high-dimensional dynamic behaviors. In addition, we develop an adaptive active learning strategy to strategically identify informative spatial locations for data collection and further maximize the prediction accuracy. This strategy achieves the adaptive trade-off between the prediction uncertainty in the G-ST-GP model and the space-filling design guided by the geodesic distance across the 3D geometry. We implement the proposed framework to model the spatiotemporal electrodynamics in a 3D heart geometry. Numerical experiments show that our framework outperforms traditional methods lacking the mechanism of geometric information incorporation or effective data collection.

stat.ML

Topological Structures of Sets and their Subsets

For real application and theoretical investigation of ordinary hypergraphs and non-ordinary hypergraphs, researchers need to establish standard rules and feasible operating methods. We propose a visualization tool for investigating hypergraphs by means of the natural topological structure of finite sets and their subsets, so we are able to construct various non-ordinary hypergraphs, and to reveal topological properties (such as hamiltonian cycles, maximal planar graphs), colorings, connectivity, hypergraph group, isomorphism and homomorphism of hypergraphs.

math.HO

SpeHeatal: A Cluster-Enhanced Segmentation Method for Sperm Morphology Analysis

The accurate assessment of sperm morphology is crucial in andrological diagnostics, where the segmentation of sperm images presents significant challenges. Existing approaches frequently rely on large annotated datasets and often struggle with the segmentation of overlapping sperm and the presence of dye impurities. To address these challenges, this paper first analyzes the issue of overlapping sperm tails from a geometric perspective and introduces a novel clustering algorithm, Con2Dis, which effectively segments overlapping tails by considering three essential factors: CONnectivity, CONformity, and DIStance. Building on this foundation, we propose an unsupervised method, SpeHeatal, designed for the comprehensive segmentation of the SPErm HEAd and TAiL. SpeHeatal employs the Segment Anything Model(SAM) to generate masks for sperm heads while filtering out dye impurities, utilizes Con2Dis to segment tails, and then applies a tailored mask splicing technique to produce complete sperm masks. Experimental results underscore the superior performance of SpeHeatal, particularly in handling images with overlapping sperm.

eess.IV

Physics-augmented Deep Learning with Adversarial Domain Adaptation: Applications to STM Image Denoising

Image denoising is a critical task in various scientific fields such as medical imaging and material characterization, where the accurate recovery of underlying structures from noisy data is essential. Although supervised denoising techniques have achieved significant advancements, they typically require large datasets of paired clean-noisy images for training. Unsupervised methods, while not reliant on paired data, typically necessitate a set of unpaired clean images for training, which are not always accessible. In this paper, we propose a physics-augmented deep learning with adversarial domain adaption (PDA-Net) framework for unsupervised image denoising, with applications to denoise real-world scanning tunneling microscopy (STM) images. Our PDA-Net leverages the underlying physics to simulate and envision the ground truth for denoised STM images. Additionally, built upon Generative Adversarial Networks (GANs), we incorporate a cycle-consistency module and a domain adversarial module into our PDA-Net to address the challenge of lacking paired training data and achieve information transfer between the simulated and real experimental domains. Finally, we propose to implement feature alignment and weight-sharing techniques to fully exploit the similarity between simulated and real experimental images, thereby enhancing the denoising performance in both the simulation and experimental domains. Experimental results demonstrate that the proposed PDA-Net successfully enhances the quality of STM images, offering promising applications to enhance scientific discovery and accelerate experimental quantum material research.

eess.IV

MUSE-Net: Missingness-aware mUlti-branching Self-attention Encoder for Irregular Longitudinal Electronic Health Records

The era of big data has made vast amounts of clinical data readily available, particularly in the form of electronic health records (EHRs), which provides unprecedented opportunities for developing data-driven diagnostic tools to enhance clinical decision making. However, the application of EHRs in data-driven modeling faces challenges such as irregularly spaced multi-variate time series, issues of incompleteness, and data imbalance. Realizing the full data potential of EHRs hinges on the development of advanced analytical models. In this paper, we propose a novel Missingness-aware mUlti-branching Self-Attention Encoder (MUSE-Net) to cope with the challenges in modeling longitudinal EHRs for data-driven disease prediction. The proposed MUSE-Net is composed by four novel modules including: (1) a multi-task Gaussian process (MGP) with missing value masks for data imputation; (2) a multi-branching architecture to address the data imbalance problem; (3) a time-aware self-attention encoder to account for the irregularly spaced time interval in longitudinal EHRs; (4) interpretable multi-head attention mechanism that provides insights into the importance of different time points in disease prediction, allowing clinicians to trace model decisions. We evaluate the proposed MUSE-Net using both synthetic and real-world datasets. Experimental results show that our MUSE-Net outperforms existing methods that are widely used to investigate longitudinal signals.

cs.LG

Graph Set-colorings And Hypergraphs In Topological Coding

In order to make more complex number-based strings from topological coding for defending against the intelligent attacks equipped with quantum computing and providing effective protection technology for the age of quantum computing, we will introduce set-colored graphs admitting set-colorings that has been considerable cryptanalytic significance, and especially related with hypergraphs. We use the set-coloring of graphs to reflect the intersection of elements, and add other constraint requirements to express more connections between sets (as hyperedges). Since we try to find some easy and effective techniques based on graph theory for practical application, we use intersected-graphs admitting set-colorings defined on hyperedge sets to observe topological structures of hypergraphs, string-type Topcode-matrix, set-type Topcode-matrix, graph-type Topcode-matrix, hypergraph-type Topcode-matrix, matrix-type Topcode-matrix \emph{etc}. We will show that each connected graph is the intersected-graph of some hypergraph and investigate hypergraph's connectivity, colorings of hypergraphs, hypergraph homomorphism, hypernetworks, scale-free network generator, compound hypergraphs having their intersected-graphs with vertices to be hypergraphs (for high-dimensional extension diagram). Naturally, we get various graphic lattices, such as edge-coincided intersected-graph lattice, vertex-coincided intersected-graph lattice, edge-hamiltonian graphic lattice, hypergraph lattice and intersected-network lattice. Many techniques in this article can be translated into polynomial algorithms, since we are aiming to apply hypergraphs and graph set-colorings to homomorphic encryption and asymmetric cryptograph.

cs.CR

The Effect of Different Optimization Strategies to Physics-Constrained Deep Learning for Soil Moisture Estimation

Soil moisture is a key hydrological parameter that has significant importance to human society and the environment. Accurate modeling and monitoring of soil moisture in crop fields, especially in the root zone (top 100 cm of soil), is essential for improving agricultural production and crop yield with the help of precision irrigation and farming tools. Realizing the full sensor data potential depends greatly on advanced analytical and predictive domain-aware models. In this work, we propose a physics-constrained deep learning (P-DL) framework to integrate physics-based principles on water transport and water sensing signals for effective reconstruction of the soil moisture dynamics. We adopt three different optimizers, namely Adam, RMSprop, and GD, to minimize the loss function of P-DL during the training process. In the illustrative case study, we demonstrate the empirical convergence of Adam optimizers outperforms the other optimization methods in both mini-batch and full-batch training.

cs.LG

Physics-constrained Active Learning for Soil Moisture Estimation and Optimal Sensor Placement

Soil moisture is a crucial hydrological state variable that has significant importance to the global environment and agriculture. Precise monitoring of soil moisture in crop fields is critical to reducing agricultural drought and improving crop yield. In-situ soil moisture sensors, which are buried at pre-determined depths and distributed across the field, are promising solutions for monitoring soil moisture. However, high-density sensor deployment is neither economically feasible nor practical. Thus, to achieve a higher spatial resolution of soil moisture dynamics using a limited number of sensors, we integrate a physics-based agro-hydrological model based on Richards' equation in a physics-constrained deep learning framework to accurately predict soil moisture dynamics in the soil's root zone. This approach ensures that soil moisture estimates align well with sensor observations while obeying physical laws at the same time. Furthermore, to strategically identify the locations for sensor placement, we introduce a novel active learning framework that combines space-filling design and physics residual-based sampling to maximize data acquisition potential with limited sensors. Our numerical results demonstrate that integrating Physics-constrained Deep Learning (P-DL) with an active learning strategy within a unified framework--named the Physics-constrained Active Learning (P-DAL) framework--significantly improves the predictive accuracy and effectiveness of field-scale soil moisture monitoring using in-situ sensors.

eess.SP

Automated Identication of Atrial Fibrillation from Single-lead ECGs Using Multi-branching ResNet

Atrial fibrillation (AF) is the most common cardiac arrhythmia, which is clinically identified with irregular and rapid heartbeat rhythm. AF puts a patient at risk of forming blood clots, which can eventually lead to heart failure, stroke, or even sudden death. It is of critical importance to develop an advanced analytical model that can effectively interpret the electrocardiography (ECG) signals and provide decision support for accurate AF diagnostics. In this paper, we propose an innovative deep-learning method for automated AF identification from single-lead ECGs. We first engage the continuous wavelet transform (CWT) to extract time-frequency features from ECG signals. Then, we develop a convolutional neural network (CNN) structure that incorporates ResNet for effective network training and multi-branching architectures for addressing the imbalanced data issue to process the 2D time-frequency features for AF classification. We evaluate the proposed methodology using two real-world ECG databases. The experimental results show a superior performance of our method compared with traditional deep learning models.

eess.SP

Hierarchical Deep Learning with Generative Adversarial Network for Automatic Cardiac Diagnosis from ECG Signals

Cardiac disease is the leading cause of death in the US. Accurate heart disease detection is of critical importance for timely medical treatment to save patients' lives. Routine use of electrocardiogram (ECG) is the most common method for physicians to assess the electrical activities of the heart and detect possible abnormal cardiac conditions. Fully utilizing the ECG data for reliable heart disease detection depends on developing effective analytical models. In this paper, we propose a two-level hierarchical deep learning framework with Generative Adversarial Network (GAN) for automatic diagnosis of ECG signals. The first-level model is composed of a Memory-Augmented Deep auto-Encoder with GAN (MadeGAN), which aims to differentiate abnormal signals from normal ECGs for anomaly detection. The second-level learning aims at robust multi-class classification for different arrhythmias identification, which is achieved by integrating the transfer learning technique to transfer knowledge from the first-level learning with the multi-branching architecture to handle the data-lacking and imbalanced data issue. We evaluate the performance of the proposed framework using real-world medical data from the MIT-BIH arrhythmia database. Experimental results show that our proposed model outperforms existing methods that are commonly used in current practice.

eess.SP

Strings And Colorings Of Topological Coding Towards Asymmetric Topology Cryptography

We, for anti-quantum computing, will discuss various number-based strings, such as number-based super-strings, parameterized strings, set-based strings, graph-based strings, integer-partitioned and integer-decomposed strings, Hanzi-based strings, as well as algebraic operations based on number-based strings. Moreover, we introduce number-based string-colorings, magic-constraint colorings, and vector-colorings and set-colorings related with strings. For the technique of encrypting the entire network at once, we propose graphic lattices related with number-based strings, Hanzi-graphic lattices, string groups, all-tree-graphic lattices. We study some topics of asymmetric topology cryptography, such as topological signatures, Key-pair graphs, Key-pair strings, one-encryption one-time and self-certification algorithms. Part of topological techniques and algorithms introduced here are closely related with NP-complete problems or NP-hard problems.

cs.IT

Parameterized Colorings And Labellings Of Graphs In Topological Coding

The coming quantum computation is forcing us to reexamine the cryptosystems people use. We are applying graph colorings of topological coding to modern information security and future cryptography against supercomputer and quantum computer attacks in the near future. Many of techniques introduced here are associated with many mathematical conjecture and NP-problems. We will introduce a group of W-constraint (k,d)-total colorings and algorithms for realizing these colorings in some kinds of graphs, which are used to make quickly public-keys and private-keys with anti-quantum computing, these (k,d)-total colorings are: graceful (k,d)-total colorings, harmonious (k,d)-total colorings, (k,d)-edge-magic total colorings, (k,d)-graceful-difference total colorings and (k,d)-felicitous-difference total colorings. One of useful tools we used is called Topcode-matrix with elements can be all sorts of things, for example, sets, graphs, number-based strings. Most of parameterized graphic colorings/labelings are defined by Topcode-matrix algebra here. From the application point of view, many of our coloring techniques are given by algorithms and easily converted into programs.

cs.IT

New Techniques Based On Odd-Edge Total Colorings In Topological Cryptosystem

For building up twin-graphic lattices towards topological cryptograph, we define four kinds of new odd-magic-type colorings: odd-edge graceful-difference total coloring, odd-edge edge-difference total coloring, odd-edge edge-magic total coloring, and odd-edge felicitous-difference total coloring in this article. Our RANDOMLY-LEAF-ADDING algorithms are based on adding randomly leaves to graphs for producing continuously graphs admitting our new odd-magic-type colorings. We use complex graphs to make caterpillar-graphic lattices and complementary graphic lattices, such that each graph in these new graphic lattices admits a uniformly $W$-magic total coloring. On the other hands, finding some connections between graphic lattices and integer lattices is an interesting research, also, is important for application in the age of quantum computer. We set up twin-type $W$-magic graphic lattices (as public graphic lattices vs private graphic lattices) and $W$-magic graphic-lattice homomorphism for producing more complex topological number-based strings.

math.CO