arXiv subjects

Bjoern M. Eskofier

Publications and source records attributed to Bjoern M. Eskofier.

21 records · Page 2Linked to original sources

arXiv2020

Inertial Measurements for Motion Compensation in Weight-bearing Cone-beam CT of the Knee

Involuntary motion during weight-bearing cone-beam computed tomography (CT) scans of the knee causes artifacts in the reconstructed volumes making them unusable for clinical diagnosis. Currently, image-based or marker-based methods are applied to correct for this motion, but often require long execution or preparation times. We propose to attach an inertial measurement unit (IMU) containing an accelerometer and a gyroscope to the leg of the subject in order to measure the motion during the scan and correct for it. To validate this approach, we present a simulation study using real motion measured with an optical 3D tracking system. With this motion, an XCAT numerical knee phantom is non-rigidly deformed during a simulated CT scan creating motion corrupted projections. A biomechanical model is animated with the same tracked motion in order to generate measurements of an IMU placed below the knee. In our proposed multi-stage algorithm, these signals are transformed to the global coordinate system of the CT scan and applied for motion compensation during reconstruction. Our proposed approach can effectively reduce motion artifacts in the reconstructed volumes. Compared to the motion corrupted case, the average structural similarity index and root mean squared error with respect to the no-motion case improved by 13-21% and 68-70%, respectively. These results are qualitatively and quantitatively on par with a state-of-the-art marker-based method we compared our approach to. The presented study shows the feasibility of this novel approach, and yields promising results towards a purely IMU-based motion compensation in C-arm CT.

cs.CV↗

arXiv2017

Stride Length Estimation with Deep Learning

Accurate estimation of spatial gait characteristics is critical to assess motor impairments resulting from neurological or musculoskeletal disease. Currently, however, methodological constraints limit clinical applicability of state-of-the-art double integration approaches to gait patterns with a clear zero-velocity phase. We describe a novel approach to stride length estimation that uses deep convolutional neural networks to map stride-specific inertial sensor data to the resulting stride length. The model is trained on a publicly available and clinically relevant benchmark dataset consisting of 1220 strides from 101 geriatric patients. Evaluation is done in a 10-fold cross validation and for three different stride definitions. Even though best results are achieved with strides defined from mid-stance to mid-stance with average accuracy and precision of 0.01 $\pm$ 5.37 cm, performance does not strongly depend on stride definition. The achieved precision outperforms state-of-the-art methods evaluated on this benchmark dataset by 3.0 cm (36%). Due to the independence of stride definition, the proposed method is not subject to the methodological constrains that limit applicability of state-of-the-art double integration methods. Furthermore, precision on the benchmark dataset could be improved. With more precise mobile stride length estimation, new insights to the progression of neurological disease or early indications might be gained. Due to the independence of stride definition, previously uncharted diseases in terms of mobile gait analysis can now be investigated by re-training and applying the proposed method.

cs.LG↗

arXiv2017

Sensor-based Gait Parameter Extraction with Deep Convolutional Neural Networks

Measurement of stride-related, biomechanical parameters is the common rationale for objective gait impairment scoring. State-of-the-art double integration approaches to extract these parameters from inertial sensor data are, however, limited in their clinical applicability due to the underlying assumptions. To overcome this, we present a method to translate the abstract information provided by wearable sensors to context-related expert features based on deep convolutional neural networks. Regarding mobile gait analysis, this enables integration-free and data-driven extraction of a set of 8 spatio-temporal stride parameters. To this end, two modelling approaches are compared: A combined network estimating all parameters of interest and an ensemble approach that spawns less complex networks for each parameter individually. The ensemble approach is outperforming the combined modelling in the current application. On a clinically relevant and publicly available benchmark dataset, we estimate stride length, width and medio-lateral change in foot angle up to ${-0.15\pm6.09}$ cm, ${-0.09\pm4.22}$ cm and ${0.13 \pm 3.78^\circ}$ respectively. Stride, swing and stance time as well as heel and toe contact times are estimated up to ${\pm 0.07}$, ${\pm0.05}$, ${\pm 0.07}$, ${\pm0.07}$ and ${\pm0.12}$ s respectively. This is comparable to and in parts outperforming or defining state-of-the-art. Our results further indicate that the proposed change in methodology could substitute assumption-driven double-integration methods and enable mobile assessment of spatio-temporal stride parameters in clinically critical situations as e.g. in the case of spastic gait impairments.

cs.LG↗