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Bo Gao

Publications and source records attributed to Bo Gao.

At least 19 recordsLinked to original sources

Improving O-RADS Risk Stratification from Ultrasound Reports: A Comparative Evaluation of Hybrid versus End-to-End LLM Reasoning Strategies

Background: Automating clinical guideline-based decision-making with large language models (LLMs) remains challenging because of reliability, hallucination, and limited interpretability. We compared the performance of LLMs and reasoning strategies for automated Ovarian-Adnexal Reporting and Data System (O-RADS) classification from free-text pelvic ultrasound reports. Methods: In this retrospective study, consecutive patients with ovarian masses who underwent pelvic ultrasound were included. Eight LLMs were tested with three reasoning strategies: implicit-knowledge end-to-end, rule-informed end-to-end, and a feature-based hybrid architecture that decoupled feature extraction from rule-based classification. The reference standard was O-RADS categorization established by expert consensus. Results: A total of 310 women with 390 ovarian masses were evaluated. The feature-based hybrid architecture using Gemini 3.6 Flash demonstrated the best performance, achieving an accuracy of 99.2% (387 of 390) and almost perfect agreement with the reference standard (weighted kappa = 1.00; 95% CI: 0.99-1.00). Its performance surpassed that of original clinical reports (accuracy, 87.7% [342 of 390]; weighted kappa = 0.94; 95% CI: 0.91-0.96) and end-to-end LLM strategies (accuracy range, 65.6% [256 of 390] to 95.9% [374 of 390]). For structured feature extraction, Gemini 3.6 Flash demonstrated higher overall accuracy than Claude Fable 5 (98.9% vs 97.8%; P < 0.001). The hybrid architecture reduced misclassification errors and mitigated the overstaging tendency observed in original reports. Conclusion: The feature-based hybrid LLM architecture that separates clinical feature extraction from deterministic guideline execution enables highly accurate, reliable, and interpretable automated O-RADS classification, providing a promising approach for standardized, guideline-based clinical decision-making.

cs.AI

Enhanced Rydberg-Atom Superheterodyne Detection of Hidden-Photon Dark Matter on Chips

Although hidden-photon dark matter with masses above $10^{-4}\,\mathrm{eV}$ is well motivated by inflationary production, it remains largely unexplored by terrestrial experiments. Through kinetic mixing, hidden photons induce a weak oscillating electric field above $10\,\mathrm{GHz}$. We propose to amplify this signal using a compact high-frequency distributed cavity and detect it with chip-scale Rydberg-atom superheterodyne spectroscopy. Combining resonant enhancement, large dipole moments of Rydberg atoms, and long-term stable integration, this approach can probe hidden-photon dark matter in the mass range $5 \times 10^{-5}\text{--}7\times 10^{-4}\,\mathrm{eV}$ with sensitivities $3$--$4$ orders of magnitude beyond existing limits.

hep-ph

Steering topology distributions for unified generative design of architected metamaterials

Architected metamaterials derive their functions from structure, creating vast opportunities to program physical responses through topology design. However, existing design methods are often tailored to individual design problems, making limited use of topology knowledge for effective and broadly applicable design as objectives, constraints, and physical functions change. Here we introduce Generative Topology Optimization (GenTO), a unified framework that turns a learned topology prior into a reusable design engine. GenTO trains a diffusion model on a large full-order topology dataset and then iteratively steers the resulting topology distribution toward task-specific high-performing regions using user-defined physical objectives and constraints. This shifts the object of optimization from a single structure to a task-adapted topology distribution. Across topology design problems spanning thermal extremization, multi-objective morphology control, property-targeted auxetic design, and vibration transmission design, GenTO reuses pretrained topology priors for heterogeneous tasks, preserves structural diversity, and reaches high-performing solutions supported by numerical benchmarks and experimental validation. These results establish reusable topology knowledge as a unified principle for effective and scalable architected metamaterial design.

cs.AI

PCDM: A Diffusion-Based Data Poisoning Attack Against Federated Learning Systems

Federated learning (FL) is vulnerable to data poisoning attacks due to its distributed nature. Although recent GAN-based data poisoning methods have indicated the potential of using generative AI to generate seemingly legitimate poisoned data, the inherent consistency of GAN outputs can still reveal a sign of data poisoning. In this paper, we propose a diffusion-based data poisoning framework against FL systems, which leverages a Poisoning-Oriented Conditional Diffusion Model (PCDM) to enable fine-grained control over the local generation of poisoned data while ensuring both attack effectiveness and stealthiness. Our PCDM incorporates an adjustable poisoning vector within the global context to precisely control the generation of poisoned data, with theoretical guarantees on attack performance. Furthermore, it employs a novel jumping diffusion strategy for lightweight and efficient poisoned data generation. We conduct the most systematic and broad experimental evaluation for FL poisoning attacks against various defenses, including advanced Byzantine robust aggregation mechanisms, on four open datasets: MNIST, Fashion-MNIST, CIFAR-10, CIFAR-100, and a real-world wireless-specific dataset VRAI. Our results demonstrate that PCDM is less likely to exhibit statistical anomalies compared with the state-of-the-art methods while more effectively degrading global FL performance, which poses a significant risk to data security in FL.

cs.CR

Reward-Decomposed Reinforcement Learning for Immersive Video Role-Playing

Text-based role-playing models can imitate character styles, but often fail to capture scene atmosphere and evolving tension, which are crucial for immersive applications such as VR games and interactive narratives. We study video-grounded role-playing dialogue and introduce EBM-RL (Eye--Brain--Mouth Reinforcement Learning), a decoupled GRPO-based framework that separates observation ( ), reasoning ( ), and utterance generation ( ). This design mimics the human See-Think-Speak process, enabling the model to ground dialogue in visual perception before reasoning and response generation. To optimize this See-Think-Speak process, EBM-RL integrates complementary rewards for scene--text alignment, perceptual--cognitive utility, answer faithfulness, and format consistency. Extensive experiments show that EBM-RL substantially outperforms text-only role-playing baselines and larger-scale vision-language models on our immersive role-playing benchmark, improving both visual-atmosphere consistency and character authenticity. Moreover, EBM-RL demonstrates strong zero-shot transfer to out-of-domain VideoQA benchmarks without additional fine-tuning. We also release an open-source dataset for video-grounded role-playing dialogue.

cs.AI

BOOKAGENT: Orchestrating Safety-Aware Visual Narratives via Multi-Agent Cognitive Calibration

Recent advancements in Large Generative Models (LGMs) have revolutionized multi-modal generation. However, generating illustrated storybooks remains an open challenge, where prior works mainly decompose this task into separate stages, and thus, holistic multi-modal grounding remains limited. Besides, while safety alignment is studied for text- or image-only generation, existing works rarely integrate child-specific safety constraints into narrative planning and sequence-level multi-modal verification. To address these limitations, we propose BookAgent, a safety-aware multi-agent collaboration framework designed for high-quality, safety-aware visual narratives. Different from prior story visualization models that assume a fixed storyline sequence, BookAgent targets end-to-end storybook synthesis from a user draft by jointly planning, scripting, illustrating, and globally repairing inconsistencies. To ensure precise multi-modal grounding, BookAgent dynamically calibrates page-level alignment between textual scripts and visual layouts. Furthermore, BookAgent calibrates holistic consistency from the temporal dimension, by verifying-then-rectifying global inconsistencies in character identity and storytelling logic. Extensive experiments demonstrate that BookAgent significantly outperforms current methods in narrative coherence, visual consistency, and safety compliance, offering a robust paradigm for reliable agents in complex multi-modal creation. The implementation will be publicly released at https://github.com/bogao-code/BookAgent/tree/main.

cs.CV

CoT2-Meta: Budgeted Metacognitive Control for Test-Time Reasoning

Recent test-time reasoning methods improve performance by generating more candidate chains or searching over larger reasoning trees, but they typically lack explicit control over when to expand, what to prune, how to repair, and when to abstain. We introduce CoT2-Meta, a training-free metacognitive reasoning framework that combines object-level chain-of-thought generation with meta-level control over partial reasoning trajectories. The framework integrates four components: strategy-conditioned thought generation, tree-structured search, an online process oracle for step-level reasoning evaluation, and a meta-controller that allocates computation through expansion, pruning, repair, stopping, and fallback decisions. Under matched inference budgets, CoT2-Meta consistently outperforms strong single-path, sampling-based, and search-based baselines, including ReST-MCTS. On the default backbone, it achieves 92.8 EM on MATH, 90.4 accuracy on GPQA, 98.65 EM on GSM8K, 75.8 accuracy on BBEH, 85.6 accuracy on MMMU-Pro, and 48.8 accuracy on HLE, with gains over the strongest non-CoT2-Meta baseline of +3.6, +5.2, +1.15, +2.0, +4.3, and +4.3 points, respectively. Beyond these core results, the framework remains effective across a broader 15-benchmark suite spanning knowledge and QA, multi-hop reasoning, coding, and out-of-distribution evaluation. Additional analyses show better compute scaling, improved calibration, stronger selective prediction, targeted repair behavior, and consistent gains across backbone families. These results suggest that explicit metacognitive control is a practical design principle for reliable and compute-efficient test-time reasoning systems.

cs.AI

UniMamba: A Unified Spatial-Temporal Modeling Framework with State-Space and Attention Integration

Multivariate time series forecasting is fundamental to numerous domains such as energy, finance, and environmental monitoring, where complex temporal dependencies and cross-variable interactions pose enduring challenges. Existing Transformer-based methods capture temporal correlations through attention mechanisms but suffer from quadratic computational cost, while state-space models like Mamba achieve efficient long-context modeling yet lack explicit temporal pattern recognition. Therefore we introduce UniMamba, a unified spatial-temporal forecasting framework that integrates efficient state-space dynamics with attention-based dependency learning. UniMamba employs a Mamba Variate-Channel Encoding Layer enhanced with FFT-Laplace Transform and TCN to capture global temporal dependencies, and a Spatial Temporal Attention Layer to jointly model inter-variate correlations and temporal evolution. A Feedforward Temporal Dynamics Layer further fuses continuous and discrete contexts for accurate forecasting. Comprehensive experiments on eight public benchmark datasets demonstrate that UniMamba consistently outperforms state-of-the-art forecasting models in both forecasting accuracy and computational efficiency, establishing a scalable and robust solution for long-sequence multivariate time-series prediction.

cs.LG

All-optical intracellular thermal profiling using nanodiamond-based "thermal radar"

The local thermal conductivity (\k{appa}) is a pivotal biophysical parameter, governing intracellular heat flux and underlying functional processes like metabolic regulation and stress response. However, label-free mapping with sub-micron resolution in living cells remains challenge. Here, we present frequency-domain fluorescence thermometry (FD-FTM), an all-optical method based on a hybrid nanodiamond-on-gold-membrane platform, which enables quantitative mapping of \k{appa} in biological systems. Fluorescence nanodiamonds (FNDs) are deposited on substrates coated with a 50 nm gold membrane, where FNDs function as nanoscale thermometers, and the gold membrane serves as a photothermal heat source. We validate FD-FTM across reference materials and biological media, with fitting uncertainties of ~10%. By varying the modulation frequency, we tune the thermal penetration depths, enabling controlled heat propagation from the substrate to the cell nucleus. The method delivers sensitivity sufficient to resolve changes in biofluid thermal conductivity on the order of 16% relative to water. Using these capabilities, we demonstrate non-invasive thermal profiling across scales: at the cellular level, nuclear chromatin packing yields \k{appa} higher by ~10% relative to the cytoplasm; at the organelle level, we resolve \k{appa} variations associated with protein aggregates formed during liquid-liquid phase separation in an amyotrophic lateral sclerosis disease model. Temporal measurements in living cells over 30 minutes further reveal spatially resolved intracellular responses to osmotic stress, linking nanoscale thermal dynamics to biomolecular condensates. These results establish FD-FTM as a label-free, robust, and quantitative platform for thermally decoding intracellular processes, opening avenues for studying metabolic heterogeneity, disease mechanisms, and therapeutic responses.

physics.bio-ph

ODAR: Principled Adaptive Routing for LLM Reasoning via Active Inference

The paradigm of large language model (LLM) reasoning is shifting from parameter scaling to test-time compute scaling, yet many existing approaches still rely on uniform brute-force sampling (for example, fixed best-of-N or self-consistency) that is costly, hard to attribute, and can trigger overthinking with diminishing returns. We propose ODAR-Expert, an adaptive routing framework that optimizes the accuracy-efficiency trade-off via principled resource allocation. ODAR uses a difficulty estimator grounded in amortized active inference to dynamically route queries between a heuristic Fast Agent and a deliberative Slow Agent. We further introduce a free-energy-principled, risk-sensitive fusion mechanism that selects answers by minimizing a variational free energy objective, balancing log-likelihood with epistemic uncertainty (varentropy) as a principled alternative to ad hoc voting over heterogeneous candidates. Extensive evaluation across 23 benchmarks shows strong and consistent gains, including 98.2% accuracy on MATH and 54.8% on Humanity's Last Exam (HLE), while improving the compute-accuracy frontier under compute-matched settings. We also validate reproducibility on a fully open-source stack (Llama 4 + DeepSeek), where ODAR surpasses homogeneous sampling strategies while reducing computational costs by 82%. Overall, our results suggest that thinking-optimal scaling requires adaptive resource allocation with free-energy-based decision-making rather than simply increasing test-time compute.

cs.AI

An exploration of lateral optical forces from a triangular periodic motif

This computational study investigates lateral optical forces in asymmetric dielectric nanostructures, focusing on their connection to resonant light-matter interactions. We examine isosceles triangular motifs that exhibit two distinct types of optical force response under plane wave illumination. Through parameter-space analysis, we identify stable zones where optical forces remain consistent and switching bands where forces change abruptly as parameters are altered. The observed force spectra show characteristic asymmetric lineshapes, suggesting Fano-resonance behavior. Eigenfrequency analysis confirms these effects arise from interference between discrete eigenmodes and continuum propagation states, with the eigenmode Q-factors correlating with transition sharpness. These findings provide insights into how structural geometry influences optical forces through resonant effects, offering guidance for designing optically-driven systems where controlled optical force responses are desired.

physics.optics

DTP: A Simple yet Effective Distracting Token Pruning Framework for Vision-Language Action Models

Vision-Language Action (VLA) models have shown remarkable progress in robotic manipulation by leveraging the powerful perception abilities of Vision-Language Models (VLMs) to understand environments and directly output actions. However, by default, VLA models may overly attend to image tokens in the task-irrelevant region, which we describe as 'distracting tokens'. This behavior can disturb the model from the generation of the desired action tokens in each step, affecting the success rate of tasks. In this paper, we introduce a simple yet effective plug-and-play Distracting Token Pruning (DTP) framework, which dynamically detects and prunes these distracting image tokens. By correcting the model's visual attention patterns, we aim to improve the task success rate, as well as exploring the performance upper boundaries of the model without altering its original architecture or adding additional inputs. Experiments on the SIMPLER Benchmark (Li et al., 2024) show that our method consistently achieving relative improvements in task success rates across different types of novel VLA models, demonstrating generalizability to transformer-based VLAs. Further analysis reveals a negative correlation between the task success rate and the amount of attentions in the task-irrelevant region for all models tested, highlighting a common phenomenon of VLA models that could guide future research. We also publish our code at: https://anonymous.4open.science/r/CBD3.

cs.CV

MODE: Efficient Time Series Prediction with Mamba Enhanced by Low-Rank Neural ODEs

Time series prediction plays a pivotal role across diverse domains such as finance, healthcare, energy systems, and environmental modeling. However, existing approaches often struggle to balance efficiency, scalability, and accuracy, particularly when handling long-range dependencies and irregularly sampled data. To address these challenges, we propose MODE, a unified framework that integrates Low-Rank Neural Ordinary Differential Equations (Neural ODEs) with an Enhanced Mamba architecture. As illustrated in our framework, the input sequence is first transformed by a Linear Tokenization Layer and then processed through multiple Mamba Encoder blocks, each equipped with an Enhanced Mamba Layer that employs Causal Convolution, SiLU activation, and a Low-Rank Neural ODE enhancement to efficiently capture temporal dynamics. This low-rank formulation reduces computational overhead while maintaining expressive power. Furthermore, a segmented selective scanning mechanism, inspired by pseudo-ODE dynamics, adaptively focuses on salient subsequences to improve scalability and long-range sequence modeling. Extensive experiments on benchmark datasets demonstrate that MODE surpasses existing baselines in both predictive accuracy and computational efficiency. Overall, our contributions include: (1) a unified and efficient architecture for long-term time series modeling, (2) integration of Mamba's selective scanning with low-rank Neural ODEs for enhanced temporal representation, and (3) substantial improvements in efficiency and scalability enabled by low-rank approximation and dynamic selective scanning.

cs.LG

A Symmetric Superconducting Dome Hosts Non-Fermi Liquid Behavior at Optimal Doping in MoS2

The similarities between the phase diagrams of ionic liquid-gated transition metal dichalcogenides (TMDCs) and high-temperature superconductors have garnered considerable interest due to the presence of a superconducting dome with a non-monotonic dependence of the superconducting order parameter as a function of charge carrier density. However, the lack of a complete superconducting dome and insights into the normal state in ionic liquid-gated TMDCs prevents a detailed mapping between the two systems. In this work, we obtain a symmetric superconducting dome that extends from deep underdoped regime all the way to deep overdoped regime in ionic liquid gated MoS2 with a refined gating protocol. We demonstrate that the dome is anticorrelated with the evolution of non-Fermi liquid behavior in the normal states. The scattering rate in the non-Fermi liquid regime can reach Planckian limit. The results may shed light on the emergence of superconductivity in TMDCs.

cond-mat.supr-con

Climate change impacts on supra-permafrost soil and aquifer hydrology: broader, deeper, and longer activity

The thermal dynamics and hydrology of active layer soils and supra-permafrost aquifers determine the fate of the vast pool of carbon that they hold. In permafrost watersheds of Arctic Alaska, air temperature has warmed by up to 3.5 {\deg}C and snowfall has increased by up to ~40 mm from 1981 to 2020. How these changes impact the seasonal to decadal hydrological activity of the carbon-rich aquifers is mostly unknown. Observation-informed thermal hydrology modeling of a hillslope drained by a headwater stream (Imnavait Creek) within continuous permafrost showed profound changes from 1981 to 2020. Warmer summer temperatures deepened annual thaw depths. Steadily warming winter air temperatures, heavier snowfall, and stored energy from summer increased annual water outflow from the hillslope aquifer to the stream, warmed soil temperatures, and expanded and prolonged zero-curtain (stable at 0 {\deg}C) zones. In 2017-2018, zero-curtain areas with liquid water persisted through winter. Our findings reveal that both summer and winter warming drive year-round aquifer dynamics, creating conditions that amplify the permafrost-carbon-climate feedback.

physics.geo-ph

DFIR-DETR: Frequency-Domain Iterative Refinement and Dynamic Feature Aggregation for Small Object Detection

Small object detection in complex scenes exposes a fundamental tension in neural network design: backbone attention distributes computation uniformly regardless of content, pyramid necks inflate activation magnitudes during upsampling without norm compensation, and bottleneck convolutions progressively smooth high-frequency edge components through accumulated spatial filtering. In response, we develop DFIR-DETR by tracing each proposed module back to a specific, measurable deficiency in the RT-DETR baseline: uniform attention that ignores spatial complexity, norm drift that destabilises upsampled features, and spatial convolutions that progressively suppress the high-frequency components small objects depend on. On NEU-DET and VisDrone, DFIR-DETR achieves 92.9% and 51.6% mAP50 with only 11.7M parameters and 47.2 GFLOPs, demonstrating consistent gains across two qualitatively different detection domains.

cs.CV

Testing Electromagnetic Memory via Acceleration-Induced Phase Imprints in Superconductors

Electromagnetic memory is an infrared observable of gauge theory associated with soft photons and large gauge transformations. Despite its fundamental theoretical importance, it has not yet been experimentally verified. From a phenomenological perspective, a transient electromagnetic configuration can leave a persistent gauge-invariant phase imprint on charged coherent states after the local field has vanished. We point out that the electric field and associated gauge potential induced inside a normal conductor by gravitational acceleration can provide a clean source for imprinting this phase, and it can then be read out through a superconducting protocol. For representative parameters, the predicted signal can lie within the range of present sensitivities, providing a possible tabletop route toward testing electromagnetic memory.

hep-ph

A Giant Peanut-shaped Ultra-High-Energy Gamma-Ray Emitter Off the Galactic Plane

Ultra-high-energy (UHE), exceeding 100 TeV (10^12 electronvolts), {\gamma}-rays manifests extreme particle acceleration in astrophysical sources. Recent observations by {\gamma}-ray telescopes, particularly by the Large High Altitude Air Shower Observatory (LHAASO), have revealed a few tens of UHE sources, indicating numerous Galactic sources capable of accelerating particles to PeV (10^15 electronvolts) energies. However, discerning the dominant acceleration mechanisms (leptonic versus hadronic), the relative contributions of specific source classes, and the role of particle transport in shaping their observed emission are central goals of modern UHE astrophysics. Here we report the discovery of a giant UHE {\gamma}-ray emitter at -17.5{\deg} off the Galactic plane - a region where UHE {\gamma}-ray sources are rarely found. The emitter exhibits a distinctive asymmetric shape, resembling a giant "Peanut" spanning 0.45{\deg} \times 4.6{\deg}, indicative of anisotropic particle distribution over a large area. A highly aged millisecond pulsar (MSP) J0218+4232 is the sole candidate accelerator positionally coincident with the Peanut region. Its association with UHE {\gamma}-rays extending to 0.7 PeV, if confirmed, would provide the first evidence of a millisecond pulsar powering PeV particles. Such a finding challenges prevailing models, which posit that millisecond pulsars cannot sustain acceleration to PeV energies. The detection reveals fundamental gaps in understanding particle acceleration, cosmic-ray transport, and interstellar magnetic field effects, potentially revealing new PeV accelerator (PeVatron) classes.

astro-ph.HE