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Bodong Du

Publications and source records attributed to Bodong Du.

9 recordsLinked to original sources

SCIRIGOR:Evaluating Open-Ended Scientific Analysis Beyond Final Scores

Scientific coding agents produce interdependent code, results, figures, and claims, yet evaluating final outputs alone does not establish whether their conclusions are scientifically supported. We formulate evidence-grounded multimodal scientific analysis, requiring agents to produce executable analyses and claims supported by results and visualizations from the same run. We introduce SciRIGOR, an evaluation framework and benchmark comprising 100 cases from scientific articles across six domains and 17 subfields. The framework reconstructs typed evidence graphs, separates artifact fidelity from relational validity, and scores complete claim-support paths while localizing the earliest unsupported relation. Source-grounded alternative paths accommodate scientifically equivalent analyses and visualizations. We evaluate 11 agent/model configurations. On full-benchmark runs, claims agree with faithful and unfaithful results at nearly identical rates (91.8% versus 91.0%). Yet no system exceeds 62.6% on the soft evidence-chain score or 18.0% strict whole-chain success. These findings show that internal coherence does not establish scientific correctness: evaluation must verify support along the complete data-to-claim path.

cs.AI

Benchmarking Vision-Language Models for Automated Pathology Diagnosis and Report Generation

The rapid advancement of vision-language models (VLMs) has accelerated progress in computational pathology; however, whole-slide image (WSI)-based pathology report generation remains limited by the scarcity of large-scale WSI--report datasets and the complexity of mapping spatially distributed visual patterns to structured clinical text. To address this, we introduce a clinically curated Pan-Asia WSI--report dataset of approximately 10,500 pairs from five institutions and establish the REG 2025 benchmark through a MICCAI challenge for systematic evaluation of multimodal models. We analyze submitted methods spanning pretrained VLMs, multiple-instance learning frameworks, hierarchical expert models, retrieval-augmented generation, and cross-modal Transformers. Rather than indicating that VLM use alone was sufficient for superior performance, the results suggest that top-performing methods benefited from structured report representations, hierarchical diagnostic decomposition, and effective multimodal grounding. We identify key limitations, including instability in quantitative attribute estimation (e.g., numeric hallucination) and a tendency toward diagnostic overspecification, with some errors resembling known diagnostic pitfalls in routine pathology. These findings establish REG 2025 as a benchmark for evaluating WSI-based structured report generation and vision-language understanding in computational pathology, providing insights for the design of clinically grounded multimodal pathology models.

cs.CV

Beyond Frame Selection: Generative Latent Evidence Aggregation for Long-Video Understanding

Long-video understanding commonly compresses videos into a small set of frames or visual tokens for answer generation. Existing compact pipelines focus on retaining relevant visual content as explicit evidence. Yet making evidence available does not ensure that complementary cues across moments are integrated for answering. Our key idea is to organize selected frames into query-relevant cross-frame evidence before generation. We formulate this post-selection stage as a latent evidence interface and instantiate it with GenEvA ($\textbf{Gen}erative$ $Latent$ $\textbf{Ev}idence$ $\textbf{A}ggregation$), a distribution-guided latent evidence aggregation framework. Specifically, GenEvA uses a query-conditioned evidence distribution to focus aggregation on relevant frames, forming compact cross-frame latent evidence from their frame-specific information. Since cross-frame integration is not always needed, the same distribution determines whether to insert this latent complement. Across four benchmarks and two Video-MLLM backbones, GenEvA consistently improves matched-frame baselines. At 8 frames, it raises the four-benchmark LLaVA-Video average by $+5.2$ points and Qwen2.5-VL accuracy on LVBench by $+10.1$ points. These gains require only $0.11\%$--$0.40\%$ average video-token overhead; analyses further show task-aware allocation and benefits from Adaptive Evidence Invocation.

cs.CV

MedHorizon: Towards Long-context Medical Video Understanding in the Wild

Medical multimodal large language models (MLLMs) have advanced image understanding and short-video analysis, but real clinical review often requires full-procedure video understanding. Unlike general long videos, medical procedures contain highly redundant anatomical views, while decisive evidence is temporally sparse, spatially subtle, and context dependent. Existing benchmarks often assume this evidence has already been localized through images, short clips, or pre-segmented videos, leaving the retrieval-before-reasoning problem under-tested. We introduce MedHorizon, an in-the-wild benchmark for long-context medical video understanding. MedHorizon preserves 759 hours of full-length clinical procedures and provides 1,253 evidence-grounded multiple-choice questionsthat jointly evaluate sparse evidence understanding and multi-hop clinical reasoning. Its evidence is extremely sparse, with only 0.166% evidence frames on average, requiring models to search noisy procedural streams before interpreting and aggregating findings. We evaluate representative general-domain, medical-domain, and long-video MLLMs. The best model reaches only 41.1% accuracy, showing that current systems remain far from robust full-procedure understanding. Further analysis yields four key findings: performance does not scale reliably with more frames, evidence retrieval and clinical interpretation remain primary bottlenecks; these bottlenecks are rooted in weak procedural reasoning and attention drift under redundancy, and generic sampling methods only partially balances local detail with global coverage. MedHorizon provides a rigorous testbed for MLLMs that retrieve sparse evidence and reason over complete clinical workflows.

cs.CV

Distribution-Aware Reward Estimation for Test-Time Reinforcement Learning

Test-time reinforcement learning (TTRL) enables large language models (LLMs) to self-improve on unlabeled inputs, but its effectiveness critically depends on how reward signals are estimated without ground-truth supervision. Most existing TTRL methods rely on majority voting (MV) over rollouts to produce deterministic rewards, implicitly assuming that the majority rollout provides a reliable learning signal. We show that this assumption is fragile: MV reduces the rollout distribution into a single outcome, discarding information about non-majority but correct actions candidates, and yields systematically biased reward estimates. To address this, we propose Distribution-AwareReward Estimation (DARE), which shifts reward estimation from a single majority outcome to the full empirical rollout distribution. DARE further augments this distribution-based reward with an exploration bonus and a distribution pruning mechanism for non-majority rollout exploration and reward denoise, yielding a more informative and robust reward estimation. Extensive experiments on challenging reasoning benchmarks show that DARE improves optimization stability and final performance over recent baselines, achieving relative improvements of 25.3% on challenging AIME 2024 and 5.3% on AMC.

cs.CL

RadHiera: Semantic Hierarchical Reinforcement Learning for Medical Report Generation

Vision-language models have shown promising results in radiology report generation. However, most existing methods generate reports as flat text and do not explicitly model the semantic dependency between the Findings and Impression sections, which can lead to inconsistencies between clinical observations and diagnostic conclusions. In this paper, we propose RadHiera, a semantic hierarchical reinforcement learning framework for radiology report generation. RadHiera follows the semantic organization of radiology reports by first optimizing overall report quality, then improving the diagnostic accuracy of the Impression section, and finally enforcing consistency between Findings and Impression so that diagnostic conclusions are supported by clinical evidence. Specifically, we begin with a base reward that combines linguistic quality and medical factuality to provide supervision on the whole report. On this basis, we introduce a severity-aware reward for the Impression section that places greater emphasis on errors involving clinically critical conditions, thereby reducing both missed diagnoses and overstatement. We further enforce cross-section consistency using Expert Model-derived label sets, with subset constraints and hallucination penalties to ensure that impressions remain faithful to the findings. Experiments on three public chest X-ray benchmarks show that RadHiera consistently improves diagnostic accuracy and inter-section consistency over state-of-the-art methods, while also demonstrating good adaptability to report generation in ultrasound report generation.

cs.AI

OralGPT: A Two-Stage Vision-Language Model for Oral Mucosal Disease Diagnosis and Description

Oral mucosal diseases such as leukoplakia, oral lichen planus, and recurrent aphthous ulcers exhibit diverse and overlapping visual features, making diagnosis challenging for non-specialists. While vision-language models (VLMs) have shown promise in medical image interpretation, their application in oral healthcare remains underexplored due to the lack of large-scale, well-annotated datasets. In this work, we present \textbf{OralGPT}, the first domain-specific two-stage vision-language framework designed for oral mucosal disease diagnosis and captioning. In Stage 1, OralGPT learns visual representations and disease-related concepts from classification labels. In Stage 2, it enhances its language generation ability using long-form expert-authored captions. To overcome the annotation bottleneck, we propose a novel similarity-guided data augmentation strategy that propagates descriptive knowledge from expert-labeled images to weakly labeled ones. We also construct the first benchmark dataset for oral mucosal diseases, integrating multi-source image data with both structured and unstructured textual annotations. Experimental results on four common oral conditions demonstrate that OralGPT achieves competitive diagnostic performance while generating fluent, clinically meaningful image descriptions. This study provides a foundation for language-assisted diagnostic tools in oral healthcare.

q-bio.QM

Multi-Modal Explainable Medical AI Assistant for Trustworthy Human-AI Collaboration

Generalist Medical AI (GMAI) systems have demonstrated expert-level performance in biomedical perception tasks, yet their clinical utility remains limited by inadequate multi-modal explainability and suboptimal prognostic capabilities. Here, we present XMedGPT, a clinician-centric, multi-modal AI assistant that integrates textual and visual interpretability to support transparent and trustworthy medical decision-making. XMedGPT not only produces accurate diagnostic and descriptive outputs, but also grounds referenced anatomical sites within medical images, bridging critical gaps in interpretability and enhancing clinician usability. To support real-world deployment, we introduce a reliability indexing mechanism that quantifies uncertainty through consistency-based assessment via interactive question-answering. We validate XMedGPT across four pillars: multi-modal interpretability, uncertainty quantification, and prognostic modeling, and rigorous benchmarking. The model achieves an IoU of 0.703 across 141 anatomical regions, and a Kendall's tau-b of 0.479, demonstrating strong alignment between visual rationales and clinical outcomes. For uncertainty estimation, it attains an AUC of 0.862 on visual question answering and 0.764 on radiology report generation. In survival and recurrence prediction for lung and glioma cancers, it surpasses prior leading models by 26.9%, and outperforms GPT-4o by 25.0%. Rigorous benchmarking across 347 datasets covers 40 imaging modalities and external validation spans 4 anatomical systems confirming exceptional generalizability, with performance gains surpassing existing GMAI by 20.7% for in-domain evaluation and 16.7% on 11,530 in-house data evaluation. Together, XMedGPT represents a significant leap forward in clinician-centric AI integration, offering trustworthy and scalable support for diverse healthcare applications.

cs.CV

Rethinking the Graph Polynomial Filter via Positive and Negative Coupling Analysis

Recently, the optimization of polynomial filters within Spectral Graph Neural Networks (GNNs) has emerged as a prominent research focus. Existing spectral GNNs mainly emphasize polynomial properties in filter design, introducing computational overhead and neglecting the integration of crucial graph structure information. We argue that incorporating graph information into basis construction can enhance understanding of polynomial basis, and further facilitate simplified polynomial filter design. Motivated by this, we first propose a Positive and Negative Coupling Analysis (PNCA) framework, where the concepts of positive and negative activation are defined and their respective and mixed effects are analysed. Then, we explore PNCA from the message propagation perspective, revealing the subtle information hidden in the activation process. Subsequently, PNCA is used to analyze the mainstream polynomial filters, and a novel simple basis that decouples the positive and negative activation and fully utilizes graph structure information is designed. Finally, a simple GNN (called GSCNet) is proposed based on the new basis. Experimental results on the benchmark datasets for node classification verify that our GSCNet obtains better or comparable results compared with existing state-of-the-art GNNs while demanding relatively less computational time.

cs.LG