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Boris Shirokikh

Publications and source records attributed to Boris Shirokikh.

21 records · Page 2Linked to original sources

Deep Learning for Brain Tumor Segmentation in Radiosurgery: Prospective Clinical Evaluation

Stereotactic radiosurgery is a minimally-invasive treatment option for a large number of patients with intracranial tumors. As part of the therapy treatment, accurate delineation of brain tumors is of great importance. However, slice-by-slice manual segmentation on T1c MRI could be time-consuming (especially for multiple metastases) and subjective. In our work, we compared several deep convolutional networks architectures and training procedures and evaluated the best model in a radiation therapy department for three types of brain tumors: meningiomas, schwannomas and multiple brain metastases. The developed semiautomatic segmentation system accelerates the contouring process by 2.2 times on average and increases inter-rater agreement from 92.0% to 96.5%.

eess.IV↗

Sparse Group Inductive Matrix Completion

We consider the problem of matrix completion with side information (\textit{inductive matrix completion}). In real-world applications many side-channel features are typically non-informative making feature selection an important part of the problem. We incorporate feature selection into inductive matrix completion by proposing a matrix factorization framework with group-lasso regularization on side feature parameter matrices. We demonstrate, that the theoretical sample complexity for the proposed method is much lower compared to its competitors in sparse problems, and propose an efficient optimization algorithm for the resulting low-rank matrix completion problem with sparsifying regularizers. Experiments on synthetic and real-world datasets show that the proposed approach outperforms other methods.

stat.ML↗

Tumor Delineation For Brain Radiosurgery by a ConvNet and Non-Uniform Patch Generation

Deep learning methods are actively used for brain lesion segmentation. One of the most popular models is DeepMedic, which was developed for segmentation of relatively large lesions like glioma and ischemic stroke. In our work, we consider segmentation of brain tumors appropriate to stereotactic radiosurgery which limits typical lesion sizes. These differences in target volumes lead to a large number of false negatives (especially for small lesions) as well as to an increased number of false positives for DeepMedic. We propose a new patch-sampling procedure to increase network performance for small lesions. We used a 6-year dataset from a stereotactic radiosurgery center. To evaluate our approach, we conducted experiments with the three most frequent brain tumors: metastasis, meningioma, schwannoma. In addition to cross-validation, we estimated quality on a hold-out test set which was collected several years later than the train one. The experimental results show solid improvements in both cases.

cs.CV↗