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Boyang Gu

Publications and source records attributed to Boyang Gu.

6 recordsLinked to original sources

Clinical-R1: Empowering Large Language Models for Faithful and Comprehensive Reasoning with Clinical Objective Relative Policy Optimization

Recent advances in large language models (LLMs) have shown strong reasoning capabilities through large-scale pretraining and post-training reinforcement learning, demonstrated by DeepSeek-R1. However, current post-training methods, such as Grouped Relative Policy Optimization (GRPO), mainly reward correctness, which is not aligned with the multi-dimensional objectives required in high-stakes fields such as medicine, where reasoning must also be faithful and comprehensive. We introduce Clinical-Objective Relative Policy Optimization (CRPO), a scalable, multi-objective, verifiable reinforcement learning method designed to align LLM post-training with clinical reasoning principles. CRPO integrates rule-based and verifiable reward signals that jointly optimize accuracy, faithfulness, and comprehensiveness without relying on human annotation. To demonstrate its effectiveness, we train Clinical-R1-3B, a 3B-parameter model for clinical reasoning. The experiments on three benchmarks demonstrate that our CRPO substantially improves reasoning on truthfulness and completeness over standard GRPO while maintaining comfortable accuracy enhancements. This framework provides a scalable pathway to align LLM reasoning with clinical objectives, enabling safer and more collaborative AI systems for healthcare while also highlighting the potential of multi-objective, verifiable RL methods in post-training scaling of LLMs for medical domains.

cs.AI

A Finite Element Method for Simulation of Coupled Dynamics of Dislocations and Fracture

This work presents a finite element method for simulating dynamic processes that involve the coupled evolution of dislocation motion and crack propagation. The method numerically solves the Concurrent Atomistic-Continuum (CAC) formulation of the conservation of linear momentum. A crystalline material is discretized at the unit-cell level using 6-node prism elements whose geometry allows dislocations and cracks to nucleate and propagate along element facets. Nanoscale simulations of single-crystal Cu, Fe, and Si demonstrate the initiation and propagation of dislocations and cracks, and these results are reproduced by the finite element method in excellent agreement with fully atomistic molecular dynamics simulations. Mesoscale simulations of single-crystal Cu further demonstrate the ability of the method to capture size-dependent brittle and ductile behavior. Under plane-strain conditions the Cu model fractures in a brittle manner, while a fully three-dimensional model exhibits curved and intersecting dislocations that blunt the crack tip and prevent crack propagation, resulting in ductile behavior. The accuracy, efficiency, and applicability of the method are discussed.

cond-mat.mtrl-sci

Scaling Laws For Mixed Quantization

Post-training quantization of Large Language Models (LLMs) has proven effective in reducing the memory and computational requirements for inference. In this study, we focus on a straightforward question: When aiming for a target accuracy or perplexity with low-precision quantization, how much high-precision computation needs to be preserved, and how fine-grained this quantization would need to be as we scale LLMs to larger sizes? We first introduce two critical metrics, named the quantization ratio ($Q_r$) and quantization block size ($Q_b$). The former measures the number of parameters quantized to low-precision arithmetic normalized by the total parameter count, whereas the latter defines the number of values within a block that share a scaling factor, akin to the block size concept introduced in the FP4 format in NVIDIA's Blackwell architecture. Through extensive and carefully controlled experiments across different models and quantization methods, we propose a unified scaling law on post-training quantization (PTQ) that can predict loss degeneration for varying $Q_r$ and $Q_b$. For $Q_r$, our scaling law implies that parameter scaling and ratio scaling have a multiplicative relationship. Consequently, larger models are more amenable to a higher quantization ratio $Q_r$, thus supporting an increase in the adoption of mixed quantization for inference. Regarding $Q_b$, our findings indicate that a small block size, similar to that used in Blackwell, is not essential for large models. Employing a small $Q_b$ can instead unnecessarily complicate the design of the hardware circuit.

cs.CL

On original and latent space connectivity in deep neural networks

We study whether inputs from the same class can be connected by a continuous path, in original or latent representation space, such that all points on the path are mapped by the neural network model to the same class. Understanding how the neural network views its own input space and how the latent spaces are structured has value for explainability and robustness. We show that paths, linear or nonlinear, connecting same-class inputs exist in all cases studied.

cs.LG

A Survey of Large Language Models in Medicine: Progress, Application, and Challenge

Large language models (LLMs), such as ChatGPT, have received substantial attention due to their capabilities for understanding and generating human language. While there has been a burgeoning trend in research focusing on the employment of LLMs in supporting different medical tasks (e.g., enhancing clinical diagnostics and providing medical education), a review of these efforts, particularly their development, practical applications, and outcomes in medicine, remains scarce. Therefore, this review aims to provide a detailed overview of the development and deployment of LLMs in medicine, including the challenges and opportunities they face. In terms of development, we provide a detailed introduction to the principles of existing medical LLMs, including their basic model structures, number of parameters, and sources and scales of data used for model development. It serves as a guide for practitioners in developing medical LLMs tailored to their specific needs. In terms of deployment, we offer a comparison of the performance of different LLMs across various medical tasks, and further compare them with state-of-the-art lightweight models, aiming to provide an understanding of the advantages and limitations of LLMs in medicine. Overall, in this review, we address the following questions: 1) What are the practices for developing medical LLMs 2) How to measure the medical task performance of LLMs in a medical setting? 3) How have medical LLMs been employed in real-world practice? 4) What challenges arise from the use of medical LLMs? and 5) How to more effectively develop and deploy medical LLMs? By answering these questions, this review aims to provide insights into the opportunities for LLMs in medicine and serve as a practical resource. We also maintain a regularly updated list of practical guides on medical LLMs at https://github.com/AI-in-Health/MedLLMsPracticalGuide

cs.CL

Reinforcement Learning Approach for Multi-Agent Flexible Scheduling Problems

Scheduling plays an important role in automated production. Its impact can be found in various fields such as the manufacturing industry, the service industry and the technology industry. A scheduling problem (NP-hard) is a task of finding a sequence of job assignments on a given set of machines with the goal of optimizing the objective defined. Methods such as Operation Research, Dispatching Rules, and Combinatorial Optimization have been applied to scheduling problems but no solution guarantees to find the optimal solution. The recent development of Reinforcement Learning has shown success in sequential decision-making problems. This research presents a Reinforcement Learning approach for scheduling problems. In particular, this study delivers an OpenAI gym environment with search-space reduction for Job Shop Scheduling Problems and provides a heuristic-guided Q-Learning solution with state-of-the-art performance for Multi-agent Flexible Job Shop Problems.

cs.AI