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Brianna M. White

Publications and source records attributed to Brianna M. White.

3 recordsLinked to original sources

Empathic and agentic artificial intelligence in nursing: perspectives on a human-centered framework for cancer care navigation in the United States

For patients experiencing cancer, nurse navigation can ease the burden of complex care by enhancing coordination of health services and patient outcomes. However, in under-resourced areas, trained nurse navigators may be limited or non-existent. In the United States, artificial intelligence (AI)-enabled digital health tools are increasingly available and may help address gaps in care coordination; however, most are not designed to specifically support nursing. This perspective piece discusses a human-centered AI framework that integrates empathic and agentic approaches grounded in the American Nurses Association's code of ethics to support nurses in the United States in cancer care navigation. The framework could augment, not replace, human empathy and agency while improving nurse workflow, patient-clinician relationships, and care coordination services in under-resourced areas.

cs.HC↗

Comparative Evaluation of Explainable Machine Learning Versus Linear Regression for Predicting County-Level Lung Cancer Mortality Rate in the United States

Lung cancer (LC) is a leading cause of cancer-related mortality in the United States. Accurate prediction of LC mortality rates is crucial for guiding targeted interventions and addressing health disparities. Although traditional regression-based models have been commonly used, explainable machine learning models may offer enhanced predictive accuracy and deeper insights into the factors influencing LC mortality. This study applied three models: random forest (RF), gradient boosting regression (GBR), and linear regression (LR) to predict county-level LC mortality rates across the United States. Model performance was evaluated using R-squared and root mean squared error (RMSE). Shapley Additive Explanations (SHAP) values were used to determine variable importance and their directional impact. Geographic disparities in LC mortality were analyzed through Getis-Ord (Gi*) hotspot analysis. The RF model outperformed both GBR and LR, achieving an R2 value of 41.9% and an RMSE of 12.8. SHAP analysis identified smoking rate as the most important predictor, followed by median home value and the percentage of the Hispanic ethnic population. Spatial analysis revealed significant clusters of elevated LC mortality in the mid-eastern counties of the United States. The RF model demonstrated superior predictive performance for LC mortality rates, emphasizing the critical roles of smoking prevalence, housing values, and the percentage of Hispanic ethnic population. These findings offer valuable actionable insights for designing targeted interventions, promoting screening, and addressing health disparities in regions most affected by LC in the United States.

cs.LG↗

The association between neighborhood obesogenic factors and prostate cancer risk and mortality: the Southern Community Cohort Study

Prostate cancer is one of the leading causes of cancer-related mortality among men in the U.S. We examined the role of neighborhood obesogenic attributes on prostate cancer risk and mortality in the Southern Community Cohort Study (SCCS). From 34,166 SCCS male participants, 28,356 were included in the analysis. We assessed relationship between neighborhood socioeconomic status (nSES) and neighborhood obesogenic environment indices including restaurant environment index, retail food environment index, parks, recreational facilities, and businesses and prostate cancer risk and mortality by controlling for individual-level factors using a multivariable Cox proportional hazards model. We further stratified prostate cancer risk analysis by race and body mass index (BMI). Median follow-up time was 133 months, and mean age was 51.62 years. There were 1,524 (5.37%) prostate cancer diagnoses and 98 (6.43%) prostate cancer deaths during follow-up. Compared to participants residing in wealthiest quintile, those residing in the poorest quintile had a higher risk of prostate cancer, particularly among non-obese men with a BMI less than 30. The restaurant environment index was associated with a higher prostate cancer risk in overweight (BMI equal or greater 25) White men. Obese Black individuals without any neighborhood recreational facilities had a 42% higher risk compared to those with any access. Compared to residents in wealthiest quintile and most walkable area, those residing within the poorest quintile or the least walkable area had a higher risk of prostate cancer death.

q-bio.QM↗