arXiv subjects

Bum Chul Kwon

Publications and source records attributed to Bum Chul Kwon.

27 records · Page 2Linked to original sources

arXiv2020

Modeling Disease Progression Trajectories from Longitudinal Observational Data

Analyzing disease progression patterns can provide useful insights into the disease processes of many chronic conditions. These analyses may help inform recruitment for prevention trials or the development and personalization of treatments for those affected. We learn disease progression patterns using Hidden Markov Models (HMM) and distill them into distinct trajectories using visualization methods. We apply it to the domain of Type 1 Diabetes (T1D) using large longitudinal observational data from the T1DI study group. Our method discovers distinct disease progression trajectories that corroborate with recently published findings. In this paper, we describe the iterative process of developing the model. These methods may also be applied to other chronic conditions that evolve over time.

cs.LG↗

arXiv2020

User-driven Analysis of Longitudinal Health Data with Hidden Markov Models for Clinical Insights

A goal of clinical researchers is to understand the progression of a disease through a set of biomarkers. Researchers often conduct observational studies, where they collect numerous samples from selected subjects throughout multiple years. Hidden Markov Models (HMMs) can be applied to discover latent states and their transition probabilities over time. However, it is challenging for clinical researchers to interpret the outcomes and to gain insights about the disease. Thus, this demo introduces an interactive visualization system called DPVis, which was designed to help researchers to interactively explore HMM outcomes. The demo provides guidelines of how to implement the clinician-in-the-loop approach for analyzing longitudinal, observational health data with visual analytics.

cs.HC↗

arXiv2020

DPVis: Visual Analytics with Hidden Markov Models for Disease Progression Pathways

Clinical researchers use disease progression models to understand patient status and characterize progression patterns from longitudinal health records. One approach for disease progression modeling is to describe patient status using a small number of states that represent distinctive distributions over a set of observed measures. Hidden Markov models (HMMs) and its variants are a class of models that both discover these states and make inferences of health states for patients. Despite the advantages of using the algorithms for discovering interesting patterns, it still remains challenging for medical experts to interpret model outputs, understand complex modeling parameters, and clinically make sense of the patterns. To tackle these problems, we conducted a design study with clinical scientists, statisticians, and visualization experts, with the goal to investigate disease progression pathways of chronic diseases, namely type 1 diabetes (T1D), Huntington's disease, Parkinson's disease, and chronic obstructive pulmonary disease (COPD). As a result, we introduce DPVis which seamlessly integrates model parameters and outcomes of HMMs into interpretable and interactive visualizations. In this study, we demonstrate that DPVis is successful in evaluating disease progression models, visually summarizing disease states, interactively exploring disease progression patterns, and building, analyzing, and comparing clinically relevant patient subgroups.

cs.LG↗

arXiv2020

GUIComp: A GUI Design Assistant with Real-Time, Multi-Faceted Feedback

Users may face challenges while designing graphical user interfaces, due to a lack of relevant experience and guidance. This paper aims to investigate the issues that users with no experience face during the design process, and how to resolve them. To this end, we conducted semi-structured interviews, based on which we built a GUI prototyping assistance tool called GUIComp. This tool can be connected to GUI design software as an extension, and it provides real-time, multi-faceted feedback on a user's current design. Additionally, we conducted two user studies, in which we asked participants to create mobile GUIs with or without GUIComp, and requested online workers to assess the created GUIs. The experimental results show that GUIComp facilitated iterative design and the participants with GUIComp had better a user experience and produced more acceptable designs than those who did not.

cs.HC↗

arXiv2019

Geono-Cluster: Interactive Visual Cluster Analysis for Biologists

Biologists often perform clustering analysis to derive meaningful patterns, relationships, and structures from data instances and attributes. Though clustering plays a pivotal role in biologists' data exploration, it takes non-trivial efforts for biologists to find the best grouping in their data using existing tools. Visual cluster analysis is currently performed either programmatically or through menus and dialogues in many tools, which require parameter adjustments over several steps of trial-and-error. In this paper, we introduce Geono-Cluster, a novel visual analysis tool designed to support cluster analysis for biologists who do not have formal data science training. Geono-Cluster enables biologists to apply their domain expertise into clustering results by visually demonstrating how their expected clustering outputs should look like with a small sample of data instances. The system then predicts users' intentions and generates potential clustering results. Our study follows the design study protocol to derive biologists' tasks and requirements, design the system, and evaluate the system with experts on their own dataset. Results of our study with six biologists provide initial evidence that Geono-Cluster enables biologists to create, refine, and evaluate clustering results to effectively analyze their data and gain data-driven insights. At the end, we discuss lessons learned and the implications of our study.

cs.HC↗

arXiv2019

SANVis: Visual Analytics for Understanding Self-Attention Networks

Attention networks, a deep neural network architecture inspired by humans' attention mechanism, have seen significant success in image captioning, machine translation, and many other applications. Recently, they have been further evolved into an advanced approach called multi-head self-attention networks, which can encode a set of input vectors, e.g., word vectors in a sentence, into another set of vectors. Such encoding aims at simultaneously capturing diverse syntactic and semantic features within a set, each of which corresponds to a particular attention head, forming altogether multi-head attention. Meanwhile, the increased model complexity prevents users from easily understanding and manipulating the inner workings of models. To tackle the challenges, we present a visual analytics system called SANVis, which helps users understand the behaviors and the characteristics of multi-head self-attention networks. Using a state-of-the-art self-attention model called Transformer, we demonstrate usage scenarios of SANVis in machine translation tasks. Our system is available at http://short.sanvis.org

cs.CL↗

arXiv2019

Thumbnails for Data Stories: A Survey of Current Practices

When people browse online news, small thumbnail images accompanying links to articles attract their attention and help them to decide which articles to read. As an increasing proportion of online news can be construed as data journalism, we have witnessed a corresponding increase in the incorporation of visualization in article thumbnails. However, there is little research to support alternative design choices for visualization thumbnails, which include resizing, cropping, simplifying, and embellishing charts appearing within the body of the associated article. We therefore sought to better understand these design choices and determine what makes a visualization thumbnail inviting and interpretable. This paper presents our findings from a survey of visualization thumbnails collected online and from conversations with data journalists and news graphics designers. Our study reveals that there exists an uncharted design space, one that is in need of further empirical study. Our work can thus be seen as a first step toward providing structured guidance on how to design thumbnails for data stories.

cs.HC↗

arXiv2018

RetainVis: Visual Analytics with Interpretable and Interactive Recurrent Neural Networks on Electronic Medical Records

We have recently seen many successful applications of recurrent neural networks (RNNs) on electronic medical records (EMRs), which contain histories of patients' diagnoses, medications, and other various events, in order to predict the current and future states of patients. Despite the strong performance of RNNs, it is often challenging for users to understand why the model makes a particular prediction. Such black-box nature of RNNs can impede its wide adoption in clinical practice. Furthermore, we have no established methods to interactively leverage users' domain expertise and prior knowledge as inputs for steering the model. Therefore, our design study aims to provide a visual analytics solution to increase interpretability and interactivity of RNNs via a joint effort of medical experts, artificial intelligence scientists, and visual analytics researchers. Following the iterative design process between the experts, we design, implement, and evaluate a visual analytics tool called RetainVis, which couples a newly improved, interpretable and interactive RNN-based model called RetainEX and visualizations for users' exploration of EMR data in the context of prediction tasks. Our study shows the effective use of RetainVis for gaining insights into how individual medical codes contribute to making risk predictions, using EMRs of patients with heart failure and cataract symptoms. Our study also demonstrates how we made substantial changes to the state-of-the-art RNN model called RETAIN in order to make use of temporal information and increase interactivity. This study will provide a useful guideline for researchers that aim to design an interpretable and interactive visual analytics tool for RNNs.

cs.LG↗

arXiv2015

Coddlers, Scientists, Adventurers, and Opportunists: Personas to Inform Online Health Community Development

As online health communities (OHCs) grow, users find it challenging to properly search, read, and contribute to the community because of its overwhelming content. Our goal is to understand OHC users' needs and requirements for better delivering large-scale OHC content. We interviewed 14 OHC users with interests in diabetes to investigate their attitudes and needs towards using OHCs and 2 OHC administrators to assess our findings. Four personas -Coddlers, Scientists, Adventurers, and Opportunists- emerged, which inform users' interaction behavior and attitudes with OHCs. An individual can possess the characteristics of multiple personas, which can also change over time. Our personas uniquely describe users' OHC participation intertwined with illness contexts compared to existing social types in general online communities. We discuss broader implications back to the literature and how our findings apply to other illness contexts in OHCs. We end with requirements for personalized delivery of large-scale OHC content.

cs.HC↗