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Cédric Allier

Publications and source records attributed to Cédric Allier.

2 recordsLinked to original sources

Graph neural networks uncover structure and functions underlying the activity of simulated neural assemblies

Graph neural networks trained to predict observable dynamics can be used to decompose the temporal activity of complex heterogeneous systems into simple, interpretable representations. Here we apply this framework to simulated neural assemblies with thousands of neurons and demonstrate that it can jointly reveal the connectivity matrix, the neuron types, the signaling functions, and in some cases hidden external stimuli. In contrast to existing machine learning approaches such as recurrent neural networks and transformers, which emphasize predictive accuracy but offer limited interpretability, our method provides both reliable forecasts of neural activity and interpretable decomposition of the mechanisms governing large neural assemblies.

q-bio.NC↗

Decomposing heterogeneous dynamical systems with graph neural networks

Natural physical, chemical, and biological dynamical systems are often complex, with heterogeneous components interacting in diverse ways. We show how simple graph neural networks can be designed to jointly learn the interaction rules and the latent heterogeneity from observable dynamics. The learned latent heterogeneity and dynamics can be used to virtually decompose the complex system which is necessary to infer and parameterize the underlying governing equations. We tested the approach with simulation experiments of interacting moving particles, vector fields, and signaling networks. While our current aim is to better understand and validate the approach with simulated data, we anticipate it to become a generally applicable tool to uncover the governing rules underlying complex dynamics observed in nature.

cs.LG↗