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C. Morel

Publications and source records attributed to C. Morel.

7 recordsLinked to original sources

TIARA: a fast gamma-ray detector for range monitoring in Proton Therapy

We developed a novel gamma-ray detection system (TIARA) for range monitoring in Particle Therapy. The system employs Cherenkov-based gamma-ray detection modules arranged around the target or patient, operated in time coincidence with a fast plastic beam monitor (described in a separate paper). This work focuses on the design and comprehensive characterization of the gamma-ray detection module. It consists of a monolithic PbF$_2$ crystal (2 $\times$ 1.5 $\times$ 1.5 cm$^{3}$) coupled to a 2 $\times$ 2 SiPM matrix from Hamamatsu. A series of beam tests at different clinical facilities (MEDICYC and ProteusOne in France, CNAO in Italy) enabled the determination of the detector time resolution under various conditions, with values ranging from 222 to 283 ps FWHM (Full Width Half Maximum). Monte Carlo simulations including the optical response of PbF$_2$ allowed for the determination of the detection efficiency as a function of particle type and energy. For the final TIARA prototype, which will be composed of 30 modules, an overall detection efficiency of 0.45% is expected. Comparison with experimental data confirmed that the modules are effectively insensitive to neutrons, yielding an excellent signal-to-noise ratio (SNR), with an estimated SNR of 17 for a module placed at 25 cm from the 148 MeV proton beam axis. These features translate into high range accuracy: while the performance varies with beam energy and irradiation conditions, a range accuracy of 3.3 mm at 2$\sigma$ significance level was achieved at low intensity with 63 MeV protons at MEDICYC, for a small irradiation spot of $\mathbf{\sim}$10$\mathbf{^{7}}$ protons.

physics.ins-det

First ClearMind gamma detector prototype for TOF-PET imaging

The ClearMind project aims to develop a TOF-PET position-sensitive detection module optimized for time and spatial resolutions and detection efficiency. For this, we use a 59 mm $\times$ 59 mm $\times$ 5 mm monolithic PbWO$_4$ (PWO) crystal, which is encapsulated within a commercial Micro-Channel Plate Photomultiplier tube MAPMT253 with a bialkali photocathode directly deposited on the crystal. We report the proof of concept of the directly deposited of a bialkali photocathode on a PWO crystal and its stability over time. The full calibration of the ClearMind photodetector module in the single-photoelectron regime is described. We measured a time resolution of 70 ps FWHM using a 20 ps pulsed laser. We present the performance of the prototype used in coincidence with a 3 $\times$ 3 $\times$ 3 mm$^3$ LYSO:Ca,Ce crystal readout by a SiPM. We obtained a coincidence time resolution of 350 ps FWHM, a spatial resolution of 4 to 5 mm, and a detection efficiency of 28 %, consistent with Monte Carlo simulations of the ClearMind detector module.

physics.ins-det

Characterization of a beam-tagging hodoscope for hadrontherapy monitoring

A beam tagging hodoscope prototype made of squared 1 mm$^2$ fibers arranged in two perpendicular planes and coupled to multi-anode photomultipliers has been studied using 65 MeV proton as well as 95 MeV/u $^{12}$C beams at various intensities. This hodoscope successfully provided 2D images of proton beams with a detection efficiency larger than 98 % with logical OR condition between the two fiber planes. The detection efficiency with a coincidence between the two planes is close to 75 % for beam intensities up to $\sim1$ MHz. Moreover, the timing resolution is around 1.8 ns FWHM. Overall, the performances show that such a technology is viable for beam monitoring during hadrontherapy.

physics.ins-det

Design study of a scintronic crystal targeting tens of picoseconds time resolution for gamma ray imaging: the ClearMind detector

We describe the concept of a new gamma ray scintronic detector targeting a time resolution of the order of 25 ps FWHM, with millimetric volume reconstruction and high detection efficiency. Its design consists of a monolithic large PbWO4 scintillating crystal with an efficient photocathode directly deposited on it. With an index of refraction higher for the photocathode than for the crystal, this design negates the total reflection effect of optical photons at the crystal/photo-detector optical interface, and thus largely improves optical coupling between the crystal and the photodetector. This allows to detect efficiently the Cherenkov light produced by 511 keV photoelectric conversions in PbWO4, and to optimize the detector time resolution. Furthermore, the low-yield, fast scintillation light produced additionally by PbWO4 increases the detected photon statistics by a factor 10, thus fostering accurate (3 dimensional) localization of the gamma ray interaction within the crystal and providing a fair measurement of the deposited energy. This paper lists the technological challenges that have to be overcome in order to build this scintronic detector. We show that all the key technologies have now been demonstrated and present results of a preliminary Monte Carlo simulation, which include an innovative event reconstruction algorithm to support the claimed performances of the detector.

physics.ins-det

Experience with wavefront sensor and deformable mirror interfaces for wide-field adaptive optics systems

Recent advances in adaptive optics (AO) have led to the implementation of wide field-of-view AO systems. A number of wide-field AO systems are also planned for the forthcoming Extremely Large Telescopes. Such systems have multiple wavefront sensors of different types, and usually multiple deformable mirrors (DMs). Here, we report on our experience integrating cameras and DMs with the real-time control systems of two wide-field AO systems. These are CANARY, which has been operating on-sky since 2010, and DRAGON, which is a laboratory adaptive optics real-time demonstrator instrument. We detail the issues and difficulties that arose, along with the solutions we developed. We also provide recommendations for consideration when developing future wide-field AO systems.

astro-ph.IM

GATE : a simulation toolkit for PET and SPECT

Monte Carlo simulation is an essential tool in emission tomography that can assist in the design of new medical imaging devices, the optimization of acquisition protocols, and the development or assessment of image reconstruction algorithms and correction techniques. GATE, the Geant4 Application for Tomographic Emission, encapsulates the Geant4 libraries to achieve a modular, versatile, scripted simulation toolkit adapted to the field of nuclear medicine. In particular, GATE allows the description of time-dependent phenomena such as source or detector movement, and source decay kinetics. This feature makes it possible to simulate time curves under realistic acquisition conditions and to test dynamic reconstruction algorithms. A public release of GATE licensed under the GNU Lesser General Public License can be downloaded at the address http://www-lphe.epfl.ch/GATE/.

physics.med-ph