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Carla Winterhalter

Publications and source records attributed to Carla Winterhalter.

2 recordsLinked to original sources

A geometry-aware framework for electromagnetic fields in GATE 10

Objective. An increasing number of medical-physics applications require the modelling of charged-particle transport in electromagnetic (EM) fields. We aim to provide GATE 10 users with a flexible mechanism for defining such fields in Monte Carlo simulations while preserving the native Geant4 particle-transport machinery. Approach. Our framework separates the handling of coordinates from EM field evaluation. Fields are attached to geometry volumes, defined in their local frame, and represented by analytic expressions, field maps, or arbitrary Python functions. They automatically follow the position and orientation of these volumes, including in nested and dynamic geometries. We validated the framework against native Geant4 transport and tested coordinate transformations, nested volumes, and dynamic geometry. We also compared the computational cost of the three field representations. Main results. The framework reproduced the native Geant4 trajectories exactly for all tested field types with direct Geant4 counterparts. Coordinate transformations introduced only floating-point-level differences, while simulations with dynamically changing geometry reproduced the equivalent static configurations exactly. All three representations produced equivalent transport. Mapped fields added at most 18% to the single-threaded runtime of analytic fields, while Python functions required 6.9 times as much. The compiled representations scaled with the number of threads, whereas Python functions became slower as threads were added. Significance. The framework adds flexible, geometry-aware EM field definitions to GATE 10 without modifying the underlying Geant4 transport machinery, and is part of the open-source GATE 10 codebase. It also provides a basis for extending GATE 10 with additional field representations in the future.

physics.med-ph↗

Feasibility of the J-PET to monitor range of therapeutic proton beams

Objective: The aim of this work is to investigate the feasibility of the Jagiellonian Positron Emission Tomography (J-PET) scanner for intra-treatment proton beam range monitoring. Approach: The Monte Carlo simulation studies with GATE and PET image reconstruction with CASToR were performed in order to compare six J-PET scanner geometries (three dual-heads and three cylindrical). We simulated proton irradiation of a PMMA phantom with a Single Pencil Beam (SPB) and Spread-Out Bragg Peak (SOBP) of various ranges. The sensitivity and precision of each scanner were calculated, and considering the setup's cost-effectiveness, we indicated potentially optimal geometries for the J-PET scanner prototype dedicated to the proton beam range assessment. Main results: The investigations indicate that the double-layer cylindrical and triple-layer double-head configurations are the most promising for clinical application. We found that the scanner sensitivity is of the order of 10$^{-5}$ coincidences per primary proton, while the precision of the range assessment for both SPB and SOBP irradiation plans was found below 1 mm. Among the scanners with the same number of detector modules, the best results are found for the triple-layer dual-head geometry. Significance: We performed simulation studies demonstrating that the feasibility of the J-PET detector for PET-based proton beam therapy range monitoring is possible with reasonable sensitivity and precision enabling its pre-clinical tests in the clinical proton therapy environment. Considering the sensitivity, precision and cost-effectiveness, the double-layer cylindrical and triple-layer dual-head J-PET geometry configurations seem promising for the future clinical application. Experimental tests are needed to confirm these findings.

physics.med-ph↗