arXiv subjects

Carlos Cinelli

Publications and source records attributed to Carlos Cinelli.

6 recordsLinked to original sources

arXiv2025

Sensitivity Analysis for Causal ML: A Use Case at Booking.com

Causal Machine Learning has emerged as a powerful tool for flexibly estimating causal effects from observational data in both industry and academia. However, causal inference from observational data relies on untestable assumptions about the data-generating process, such as the absence of unobserved confounders. When these assumptions are violated, causal effect estimates may become biased, undermining the validity of research findings. In these contexts, sensitivity analysis plays a crucial role, by enabling data scientists to assess the robustness of their findings to plausible violations of unconfoundedness. This paper introduces sensitivity analysis and demonstrates its practical relevance through a (simulated) data example based on a use case at Booking.com. We focus our presentation on a recently proposed method by Chernozhukov et al. (2023), which derives general non-parametric bounds on biases due to omitted variables, and is fully compatible with (though not limited to) modern inferential tools of Causal Machine Learning. By presenting this use case, we aim to raise awareness of sensitivity analysis and highlight its importance in real-world scenarios.

econ.EM↗

arXiv2025

Challenges in Statistics: A Dozen Challenges in Causality and Causal Inference

Causality and causal inference have emerged as core research areas at the interface of modern statistics and domains including biomedical sciences, social sciences, computer science, and beyond. The field's inherently interdisciplinary nature -- particularly the central role of incorporating domain knowledge -- creates a rich and varied set of statistical challenges. Much progress has been made, especially in the last three decades, but there remain many open questions. Our goal in this discussion is to outline research directions and open problems we view as particularly promising for future work. Throughout we emphasize that advancing causal research requires a wide range of contributions, from novel theory and methodological innovations to improved software tools and closer engagement with domain scientists and practitioners.

stat.ME↗

arXiv2024

On the minimum strength of (unobserved) covariates to overturn an insignificant result

We study conditions under which the addition of variables to a regression equation can turn a previously statistically insignificant result into a significant one. Specifically, we characterize the minimum strength of association required for these variables--both with the dependent and independent variables, or with the dependent variable alone--to elevate the observed t-statistic above a specified significance threshold. Interestingly, we show that it is considerably difficult to overturn a statistically insignificant result solely by reducing the standard error. Instead, included variables must also alter the point estimate to achieve such reversals in practice. Our results can be used to conduct sensitivity analyses against unobserved variables and to bound the maximum t-value one can obtain given different subsets of observed covariates, and may also offer algebraic explanations for patterns of reversals seen in empirical research, such as those documented by Lenz and Sahn (2021).

math.ST↗

arXiv2023

Causally Sound Priors for Binary Experiments

We introduce the BREASE framework for the Bayesian analysis of randomized controlled trials with a binary treatment and a binary outcome. Approaching the problem from a causal inference perspective, we propose parameterizing the likelihood in terms of the baselinerisk, efficacy, and adverse side effects of the treatment, along with a flexible, yet intuitive and tractable jointly independent beta prior distribution on these parameters, which we show to be a generalization of the Dirichlet prior for the joint distribution of potential outcomes. Our approach has a number of desirable characteristics when compared to current mainstream alternatives: (i) it naturally induces prior dependence between expected outcomes in the treatment and control groups; (ii) as the baseline risk, efficacy and risk of adverse side effects are quantities commonly present in the clinicians' vocabulary, the hyperparameters of the prior are directly interpretable, thus facilitating the elicitation of prior knowledge and sensitivity analysis; and (iii) we provide analytical formulae for the marginal likelihood, Bayes factor, and other posterior quantities, as well as an exact posterior sampling algorithm and an accurate and fast data-augmented Gibbs sampler in cases where traditional MCMC fails. Empirical examples demonstrate the utility of our methods for estimation, hypothesis testing, and sensitivity analysis of treatment effects.

stat.ME↗

arXiv2022

Orthogonal Statistical Learning with Self-Concordant Loss

Orthogonal statistical learning and double machine learning have emerged as general frameworks for two-stage statistical prediction in the presence of a nuisance component. We establish non-asymptotic bounds on the excess risk of orthogonal statistical learning methods with a loss function satisfying a self-concordance property. Our bounds improve upon existing bounds by a dimension factor while lifting the assumption of strong convexity. We illustrate the results with examples from multiple treatment effect estimation and generalized partially linear modeling.

stat.ML↗

arXiv2021

Long Story Short: Omitted Variable Bias in Causal Machine Learning

We develop a general theory of omitted variable bias for a wide range of common causal parameters, including (but not limited to) averages of potential outcomes, average treatment effects, average causal derivatives, and policy effects from covariate shifts. Our theory applies to nonparametric models, while naturally allowing for (semi-)parametric restrictions (such as partial linearity) when such assumptions are made. We show how simple plausibility judgments on the maximum explanatory power of omitted variables are sufficient to bound the magnitude of the bias, thus facilitating sensitivity analysis in otherwise complex, nonlinear models. Finally, we provide flexible and efficient statistical inference methods for the bounds, which can leverage modern machine learning algorithms for estimation. These results allow empirical researchers to perform sensitivity analyses in a flexible class of machine-learned causal models using very simple, and interpretable, tools. We demonstrate the utility of our approach with two empirical examples.

econ.EM↗