arXiv subjects

Carlos E. Vargas

Publications and source records attributed to Carlos E. Vargas.

14 recordsLinked to original sources

arXiv2026

Electromagnetic properties in $^{160-170}$Dy nuclei: A microscopic description by the pseudo-SU(3) shell model

The large collectivity observed in the rare earth region of the nuclear landscape is well known. The microscopic studies are difficult to perform in this region due to the enormous size of the valence spaces, a problem that can be avoided by means of the use of symmetry based models. Here we present calculations for electromagnetic properties of $^{160-170}$Dy nuclei within the pseudo-SU(3) scheme. The model Hamiltonian includes the preserving symmetry $Q\cdot Q$ term and the symmetry-breaking Nilsson and pairing terms, systematically parametrized for all members of the chain. The model is used to calculate B(E2) and B(M1) inter-band transition strengths between the ground state, $γ$ and $β$-bands. In addition, we present results for quadrupole moments and $g$ factors in these rotational bands. The results show that the pseudo-SU(3) shell model is a powerful microscopic theory for a description of electromagnetic properties of states in the normal parity sector in heavy deformed nuclei.

nucl-th↗

arXiv2026

Microscopic study of low-lying energy levels and electromagnetic properties in even-even $^{168-178}$Yb nuclei

Employing methods based on symmetries for the theoretical description of rare-earth nuclei offers many advantages. Among these, the pseudo-SU(3) shell model has proved to be a very useful method to describe characteristics of these systems and to understand various properties. A theoretical description of the low-lying energy spectrum and electromagnetic properties of isotopes $^{168-178}$Yb is carried out for the first time with this model, comparing theoretical results with the experimental values, where possible. The Hamiltonian includes the $Q \cdot Q$ term which preserves the symmetry, as well as the breaking symmetry of Nilsson and pairing terms. Additionally, three rotor type terms are included that allow us to make a subtle adjustment of the spectrum. The results show that the energy spectrum, the B(E2) transitions, the g-factors and the electric quadrupole moments can be described adequately with the model. Although the model is a powerful tool in the description of low-lying properties of normal parity in heavy deformed nuclei, it finds its strongest limitation in the abnormal parity sector, which has been left out of the description.

nucl-th↗

arXiv2026

Complexity of Nuclear States for 48Ca

In complex systems theory, there are different ways to describe a system in terms of information, such as emergence (Shannon entropy), self-organization, and com- plexity. These measures provide information about the dynamic behavior of a complex system. We study the differences in entropy and complexity for many-body systems undergoing a transition from a regular to a chaotic regime. To do this, we analyze the eigenvectors of the 48 Ca nucleus for different quadrupole-type two-body interactions. We obtain the eigenvectors by diagonalizing the two-body Hamiltonian for 48 Ca us- ing the Antoine code. We then calculate the entropy and complexity for the different quadrupole-type interactions. The differences found in information entropy and com- plexity are clear when comparing a regular system with a chaotic one. We find that the complexity of the regular and chaotic states of 48 Ca shows differences associated with its internal interactions.

nucl-th↗

arXiv2026

Theoretical study of normal deformed rotational bands of odd-mass $^{167,169,171}$Lu nuclei

The theoretical description of nuclear structure in rare earth nuclei represents a significant challenge for many shell models. This difficulty stems from the size of the configuration space involved. Methods based on symmetries provide significant advantages. Furthermore, the pseudo-SU(3) shell model has proven to be very useful in the description of these systems. In particular, we propose to study the energy spectra of the rotational bands with normal deformation at low and medium spin ($J\leq35/2$), the quadrupole moments, and the deformation parameter $γ$ associated with the states, as well as the B(E2) transition strengths in the $^{167,169,171}$Lu nuclei. The Hamiltonian includes $Q \cdot Q$, Nilsson, and pairing terms, parameterized in a systematic way, in addition to three rotor-like terms that enable fine tuning of the spectra. Our calculations predict collective rotational bands with prolate normal deformation in most cases. The exception is the $1/2^+$ band in $^{171}$Lu with a triaxial shape. The quadrupole moments vary along the bands, increasing in absolute value with spin. The $γ$ deformation parameter remains nearly constant along the bands, and the B(E2) values suggest bands with collective character and normal deformation. The agreement and limitations of the model are discussed.

nucl-th↗

arXiv2026

The Daily Dose: Workflow-Integrated Large Language Model Automation for Clinical Summarization and Trial Identification in Radiation Oncology

Objective: To describe the design and early clinical evaluation of The Daily Dose (TDD), an LLM-driven, automated clinical summarization and clinical-trial identification system integrated into routine radiation oncology practice. Design: Mixed-methods evaluation using a cross-sectional, anonymous clinician survey administered after 1 month of system deployment. Exposure: Daily automated delivery of physician-specific email summaries generated using RadOnc-GPT, including patient schedules, concise EHR-derived clinical-status summaries, and automated identification of potentially relevant clinical trials for new or consult visits. Main Outcomes and Measures: Primary outcomes included self-reported usability, satisfaction, perceived usefulness, perceived impact on workflow, time savings, and intention for continued use. Internal consistency reliability was assessed using Cronbach's $α$. Results: Among 55 respondents, 52 (94.5\%) worked in radiation oncology, and 38 (69.1\%) were attending physicians. Most participants (83.6\%) reported using TDD daily or several times per week. Mean (SD) scores were 3.89 (1.04) for usability and satisfaction, 3.43 (1.24) for perceived usefulness, and 3.80 (1.17) for impact and future use (5-point Likert scale). Overall satisfaction was positively associated with perceived time savings ($p < .001$). Participants reported variable time savings, with 27\% estimating $\geq 10$ minutes saved per day. The questionnaire demonstrated excellent internal consistency (overall Cronbach's $α$ = 0.97).

cs.CL↗

arXiv2024

Robust Optimization for Spot Scanning Proton Therapy based on Dose-Linear Energy Transfer (LET) Volume Constraints

Purpose: Historically, spot scanning proton therapy (SSPT) treatment planning utilizes dose volume constraints and linear-energy-transfer (LET) volume constraints separately to balance tumor control and organs-at-risk (OARs) protection. We propose a novel dose-LET volume constraint (DLVC)-based robust optimization (DLVCRO) method for SSPT in treating prostate cancer to obtain a desirable joint dose and LET distribution to minimize adverse events (AEs). Methods: DLVCRO treats DLVC as soft constraints controlling the joint distribution of dose and LET. Ten prostate cancer patients were included with rectum and bladder as OARs. DLVCRO was compared with the conventional robust optimization (RO) method using the worst-case analysis method. Besides the dose-volume histogram (DVH) indices, the analogous LETVH and extra-biological-dose (xBD)-volume histogram indices were also used. The Wilcoxon signed rank test was used to measure statistical significance. Results: In nominal scenario, DLVCRO significantly improved dose, LET and xBD distributions to protect OARs (rectum: V70Gy: 3.07\% vs. 2.90\%, p = .0063, RO vs. DLVCRO; $\text{LET}_{\max}$ (keV/um): 11.53 vs. 9.44, p = .0101; $\text{xBD}_{\max}$ (Gy$\cdot$keV/um): 420.55 vs. 398.79, p = .0086; bladder: V65Gy: 4.82\% vs. 4.61\%, p = .0032; $\text{LET}_{\max}$ 8.97 vs. 7.51, p = .0047; $\text{xBD}_{\max}$ 490.11 vs. 476.71, p = .0641). The physical dose distributions in targets are comparable (D2%: 98.57\% vs. 98.39\%; p = .0805; CTV D2% - D98%: 7.10\% vs. 7.75\%, p = .4624). In the worst-case scenario, DLVCRO robustly enhanced OAR while maintaining the similar plan robustness in target dose coverage and homogeneity. Conclusion: DLVCRO upgrades 2D DVH-based to 3D DLVH-based treatment planning to adjust dose/LET distributions simultaneously and robustly. DLVCRO is potentially a powerful tool to improve patient outcomes in SSPT.

physics.med-ph↗

arXiv2024

The status and challenges for prostate SBRT treatments in United States proton therapy centers: An NRG Oncology practice survey

A survey was designed to inquire about the practice of proton SBRT treatment for prostate cancer. The survey was distributed to all 30 proton therapy centers in the United States that participate in the National Clinical Trial Network in Feb. 2023. The survey focused on usage, patient selection criteria, prescriptions, target contours, dose constraints, treatment plan optimization and evaluation methods, patient-specific QA, and IGRT methods. Results: We received responses from 25 centers (83% participation). Only 8 respondent proton centers (32%) reported performing SBRT of the prostate. The remaining 17 centers cited three primary reasons for not offering this treatment: no clinical need, lack of volumetric imaging, and/or lack of clinical evidence. Only 1 center cited the reduction in overall reimbursement as a concern for not offering prostate SBRT. Several common practices among the 8 centers offering SBRT for the prostate were noted, such as using Hydrogel spacers, fiducial markers, and MRI for target delineation. Most proton centers (87.5%) utilized pencil beam scanning (PBS) delivery and completed Imaging and Radiation Oncology Core (IROC) phantom credentialing. Treatment planning typically used parallel opposed lateral beams, and consistent parameters for setup and range uncertainties were used for plan optimization and robustness evaluation. Measurements-based patient-specific QA, beam delivery every other day, fiducial contours for IGRT, and total doses of 35-40 GyRBE were consistent across all centers. However, there was no consensus on the risk levels for patient selection. Conclusion: Prostate SBRT is used in about 1/3 of proton centers in the US. There was a significant consistency in practices among proton centers treating with proton SBRT. It is possible that the adoption of proton SBRT may become more common if proton SBRT is more commonly offered in clinical trials.

physics.med-ph↗

arXiv2023

Noisy probing dose facilitated dose prediction for pencil beam scanning proton therapy: physics enhances generalizability

Purpose: Prior AI-based dose prediction studies in photon and proton therapy often neglect underlying physics, limiting their generalizability to handle outlier clinical cases, especially for pencil beam scanning proton therapy (PBSPT). Our aim is to design a physics-aware and generalizable AI-based PBSPT dose prediction method that has the underlying physics considered to achieve high generalizability to properly handle the outlier clinical cases. Methods and Materials: This study analyzed PBSPT plans of 103 prostate and 78 lung cancer patients from our institution,with each case comprising CT images, structure sets, and plan doses from our Monte-Carlo dose engine (serving as the ground truth). Three methods were evaluated in the ablation study: the ROI-based method, the beam mask and sliding window method, and the noisy probing dose method. Twelve cases with uncommon beam angles or prescription doses tested the methods' generalizability to rare treatment planning scenarios. Performance evaluation used DVH indices, 3D Gamma passing rates (3%/2mm/10%), and dice coefficients for dose agreement. Results: The noisy probing dose method showed improved agreement of DVH indices, 3D Gamma passing rates, and dice coefficients compared to the conventional methods for the testing cases. The noisy probing dose method showed better generalizability in the 6 outlier cases than the ROI-based and beam mask-based methods with 3D Gamma passing rates (for prostate cancer, targets: 89.32%$\pm$1.45% vs. 93.48%$\pm$1.51% vs. 96.79%$\pm$0.83%, OARs: 85.87%$\pm$1.73% vs. 91.15%$\pm$1.13% vs. 94.29%$\pm$1.01%). The dose predictions were completed within 0.3 seconds. Conclusions: We've devised a novel noisy probing dose method for PBSPT dose prediction in prostate and lung cancer patients. With more physics included, it enhances the generalizability of dose prediction in handling outlier clinical cases.

physics.med-ph↗

arXiv2023

Artificial Intelligence-Facilitated Online Adaptive Proton Therapy Using Pencil Beam Scanning Proton Therapy

We propose an oAPT workflow that incorporates all these functionalities and validate its clinical implementation feasibility with prostate patients. AI-based auto-segmentation tool AccuContourTM (Manteia, Xiamen, China) was seamlessly integrated into oAPT. Initial spot arrangement tool on the vCT for re-optimization was implemented using raytracing. An LET-based biological effect evaluation tool was developed to assess the overlap region of high dose and high LET in selected OARs. Eleven prostate cancer patients were retrospectively selected to verify the efficacy and efficiency of the proposed oAPT workflow. The time cost of each component in the workflow was recorded for analysis. The verification plan showed significant degradation of the CTV coverage and rectum and bladder sparing due to the interfractional anatomical changes. Re-optimization on the vCT resulted in great improvement of the plan quality. No overlap regions of high dose and high LET distributions were observed in bladder or rectum in re-plans. 3D Gamma analyses in PSQA confirmed the accuracy of the re-plan doses before delivery (Gamma passing rate = 99.57%), and after delivery (98.59%). The robustness of the re-plans passed all clinical requirements. The average time for the complete execution of the workflow was 9.12minutes, excluding manual intervention time. The AI-facilitated oAPT workflow was demonstrated to be both efficient and effective by generating a re-plan that significantly improved the plan quality in prostate cancer treated with PBSPT.

physics.med-ph↗

arXiv2023

Beam mask and sliding window-facilitated deep learning-based accurate and efficient dose prediction for pencil beam scanning proton therapy

Purpose: To develop a DL-based PBSPT dose prediction workflow with high accuracy and balanced complexity to support on-line adaptive proton therapy clinical decision and subsequent replanning. Methods: PBSPT plans of 103 prostate cancer patients and 83 lung cancer patients previously treated at our institution were included in the study, each with CTs, structure sets, and plan doses calculated by the in-house developed Monte-Carlo dose engine. For the ablation study, we designed three experiments corresponding to the following three methods: 1) Experiment 1, the conventional region of interest (ROI) method. 2) Experiment 2, the beam mask (generated by raytracing of proton beams) method to improve proton dose prediction. 3) Experiment 3, the sliding window method for the model to focus on local details to further improve proton dose prediction. A fully connected 3D-Unet was adopted as the backbone. Dose volume histogram (DVH) indices, 3D Gamma passing rates, and dice coefficients for the structures enclosed by the iso-dose lines between the predicted and the ground truth doses were used as the evaluation metrics. The calculation time for each proton dose prediction was recorded to evaluate the method's efficiency. Results: Compared to the conventional ROI method, the beam mask method improved the agreement of DVH indices for both targets and OARs and the sliding window method further improved the agreement of the DVH indices. For the 3D Gamma passing rates in the target, OARs, and BODY (outside target and OARs), the beam mask method can improve the passing rates in these regions and the sliding window method further improved them. A similar trend was also observed for the dice coefficients. In fact, this trend was especially remarkable for relatively low prescription isodose lines. The dose predictions for all the testing cases were completed within 0.25s.

physics.med-ph↗

arXiv2013

Microscopic study of neutron-rich Dysprosium isotopes

Microscopic studies in heavy nuclei are very scarce due to large valence spaces involved. This computational problem can be avoided by means of the use of symmetry based models. Ground-state, gamma and beta-bands, and their B(E2) transition strengths in 160-168Dy isotopes, are studied in the framework of the pseudo-SU(3) model which includes the preserving symmetry Q.Q term and the symmetry-breaking Nilsson and pairing terms, systematically parametrized. Additionally, three rotor-like terms are considered whose free parameters, fixed for all members of the chain are used to fine tune the moment of inertia of rotational bands and the band-head of gamma and beta-bands. The model succesfully describes in a systematic way rotational features in these nuclei and allows to extrapolate toward the midshell nucleus 170Dy. The results presented show that it is possible to study full chain of isotopes or isotones in the region with the present model.

nucl-th↗

arXiv2005

Low energy 0+ excitations in 158Gd

High precision (p,t) studies of the deformed nucleus 158Gd allowed the observation of 13 excited 0+ states below an excitation energy of 3.1 MeV. This high density of low energy states, and particularly their measured B(E2) transition strengths to the first excited 2+ state challenge nuclear models. The pseudo SU(3) model, which successfully describes many excited bands in Dy isotopes, is used to analyze this nuclei. We have fairly good reproduction of most of the states but the absence of actively including nucleons occupying intruders orbits may be the reason for the observed limitations of the model.

nucl-th↗

arXiv2003

Pseudo + quasi SU(3): Towards a shell-model description of heavy deformed nuclei

The pseudo-SU(3) model has been extensively used to study normal parity bands in even-even and odd-mass heavy deformed nuclei. The use of a realistic Hamiltonian that mixes many SU(3) irreps has allowed for a successful description of energy spectra and electromagnetic transition strengths. While this model is powerful, there are situations in which the intruder states must be taken into account explicitly. The quasi-SU(3) symmetry is expected to complement the model, allowing for a description of nucleons occupying normal and intruder parity orbitals using a unified formalism.

nucl-th↗

arXiv2002

Microscopic description of the scissors mode in odd-mass heavy deformed nuclei

Pseudo-SU(3) shell-model results are reported for M1 excitation strengths in 157-Gd, 163-Dy and 169-Tm in the energy range between 2 and 4 MeV. Non-zero pseudo-spin couplings between the configurations play a very important role in determining the M1 strength distribution, especially its rapidly changing fragmentation pattern which differs significantly from what has been found in neighboring even-even systems. The results suggest one should examine contributions from intruder levels.

nucl-th↗