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Ce Zhang

Publications and source records attributed to Ce Zhang.

257 records · Page 15Linked to original sources

A machine-compiled macroevolutionary history of Phanerozoic life

Many aspects of macroevolutionary theory and our understanding of biotic responses to global environmental change derive from literature-based compilations of palaeontological data. Existing manually assembled databases are, however, incomplete and difficult to assess and enhance. Here, we develop and validate the quality of a machine reading system, PaleoDeepDive, that automatically locates and extracts data from heterogeneous text, tables, and figures in publications. PaleoDeepDive performs comparably to humans in complex data extraction and inference tasks and generates congruent synthetic macroevolutionary results. Unlike traditional databases, PaleoDeepDive produces a probabilistic database that systematically improves as information is added. We also show that the system can readily accommodate sophisticated data types, such as morphological data in biological illustrations and associated textual descriptions. Our machine reading approach to scientific data integration and synthesis brings within reach many questions that are currently underdetermined and does so in ways that may stimulate entirely new modes of inquiry.

cs.DB↗

DimmWitted: A Study of Main-Memory Statistical Analytics

We perform the first study of the tradeoff space of access methods and replication to support statistical analytics using first-order methods executed in the main memory of a Non-Uniform Memory Access (NUMA) machine. Statistical analytics systems differ from conventional SQL-analytics in the amount and types of memory incoherence they can tolerate. Our goal is to understand tradeoffs in accessing the data in row- or column-order and at what granularity one should share the model and data for a statistical task. We study this new tradeoff space, and discover there are tradeoffs between hardware and statistical efficiency. We argue that our tradeoff study may provide valuable information for designers of analytics engines: for each system we consider, our prototype engine can run at least one popular task at least 100x faster. We conduct our study across five architectures using popular models including SVMs, logistic regression, Gibbs sampling, and neural networks.

cs.DB↗

An Approximate, Efficient Solver for LP Rounding

Many problems in machine learning can be solved by rounding the solution of an appropriate linear program (LP). This paper shows that we can recover solutions of comparable quality by rounding an approximate LP solution instead of the ex- act one. These approximate LP solutions can be computed efficiently by applying a parallel stochastic-coordinate-descent method to a quadratic-penalty formulation of the LP. We derive worst-case runtime and solution quality guarantees of this scheme using novel perturbation and convergence analysis. Our experiments demonstrate that on such combinatorial problems as vertex cover, independent set and multiway-cut, our approximate rounding scheme is up to an order of magnitude faster than Cplex (a commercial LP solver) while producing solutions of similar quality.

math.NA↗

Scaling Inference for Markov Logic with a Task-Decomposition Approach

Motivated by applications in large-scale knowledge base construction, we study the problem of scaling up a sophisticated statistical inference framework called Markov Logic Networks (MLNs). Our approach, Felix, uses the idea of Lagrangian relaxation from mathematical programming to decompose a program into smaller tasks while preserving the joint-inference property of the original MLN. The advantage is that we can use highly scalable specialized algorithms for common tasks such as classification and coreference. We propose an architecture to support Lagrangian relaxation in an RDBMS which we show enables scalable joint inference for MLNs. We empirically validate that Felix is significantly more scalable and efficient than prior approaches to MLN inference by constructing a knowledge base from 1.8M documents as part of the TAC challenge. We show that Felix scales and achieves state-of-the-art quality numbers. In contrast, prior approaches do not scale even to a subset of the corpus that is three orders of magnitude smaller.

cs.AI↗

Effects of electrostatic screening on the conformation of single DNA molecules confined in a nanochannel

Single T4-DNA molecules were confined in rectangular-shaped channels with a depth of 300 nm and a width in the range 150-300 nm casted in a poly(dimethylsiloxane) nanofluidic chip. The extensions of the DNA molecules were measured with fluorescence microscopy as a function of the ionic strength and composition of the buffer as well as the DNA intercalation level by the YOYO-1 dye. The data were interpreted with scaling theory for a wormlike polymer in good solvent, including the effects of confinement, charge, and self-avoidance. It was found that the elongation of the DNA molecules with decreasing ionic strength can be interpreted in terms of an increase of the persistence length. Self-avoidance effects on the extension are moderate, due to the small correlation length imposed by the channel cross-sectional diameter. Intercalation of the dye results in an increase of the DNA contour length and a partial neutralization of the DNA charge, but besides effects of electrostatic origin it has no significant effect on the bare bending rigidity. In the presence of divalent cations, the DNA molecules were observed to contract, but they do not collapse into a condensed structure. It is proposed that this contraction results from a divalent counterion mediated attractive force between the segments of the DNA molecule.

physics.bio-ph↗