SearcharxivSearch

arXiv subjects

Cesar Maldonado

Publications and source records attributed to Cesar Maldonado.

12 recordsLinked to original sources

Sorting ECGs by lag irreversibility

In this work we introduce the lag irreversibility function as a method to assess time-irreversibility in discrete time series. It quantifies the degree of time-asymmetry for the joint probability function of the state variable under study and the state variable lagged in time. We test its performance in a time-irreversible Markov chain model for which theoretical results are known. Moreover, we use our approach to analyze electrocardiographic recordings of four groups of subjects: healthy young individuals, healthy elderly individuals, and persons with two different disease conditions, namely, congestive heart failure and atrial fibrillation. We find that by studying jointly the variability of the amplitudes of the different waves in the electrocardiographic signals, one can obtain an efficient method to discriminate between the groups already mentioned. Finally, we test the accuracy of our method using the ROC analysis.

physics.data-an

Existence of the zero temperature limit of equilibrium states on topologically transitive countable Markov shifts

Consider a topologically transitive countable Markov shift $\Sigma$ and a summable Markov potential $\phi$ with finite Gurevich pressure and $\mathrm{Var}_1(\phi) < \infty$. We prove existence of the limit $\lim_{t \to \infty} \mu_t$ in the weak$^\star$ topology, where $\mu_t$ is the unique equilibrium state associated to the potential $t\phi$. Besides that, we present examples where the limit at zero temperature exists for potentials satisfying more general conditions.

math.DS

Thermodynamic Formalism in Neuronal Dynamics and Spike Train Statistics

The Thermodynamic Formalism provides a rigorous mathematical framework to study quantitative and qualitative aspects of dynamical systems. At its core there is a variational principle corresponding, in its simplest form, to the Maximum Entropy principle. It is used as a statistical inference procedure to represent, by specific probability measures (Gibbs measures), the collective behaviour of complex systems. This framework has found applications in different domains of science. In particular, it has been fruitful and influential in neurosciences. In this article, we review how the Thermodynamic Formalism can be exploited in the field of theoretical neuroscience, as a conceptual and operational tool, to link the dynamics of interacting neurons and the statistics of action potentials from either experimental data or mathematical models. We comment on perspectives and open problems in theoretical neuroscience that could be addressed within this formalism.

q-bio.NC

Estimating entropy rate from censored symbolic time series: a test for time-irreversibility

In this work we introduce a method for estimating entropy rate and entropy production rate from finite symbolic time series. From the point of view of statistics, estimating entropy from a finite series can be interpreted as a problem of estimating parameters of a distribution with a censored or truncated sample. We use this point of view to give estimations of entropy rate and entropy production rate assuming that they are parameters of a (limit) distribution. The last statement is actually a consequence of the fact that the distribution of estimations obtained from recurrence-time statistics satisfy the central limit theorem. We test our method using time series coming from Markov chain models, discrete-time chaotic maps and real a DNA sequence from human genome.

cond-mat.stat-mech

Freezing phase transition in a fractal potential

In this work we propose a simple example of a one-dimensional thermodynamic system where non-interacting particles are allowed to move over the $[0,1]$ interval, which are influenced by a potential with a fractal structure. We prove that the system exhibits a phase transition at a finte temperature, which is characterized by the fact that the Gibbs-Boltzmann probability measure passes from being absolutely continuous with respect to Lebesgue (at high temperature) to being singular continuous (at low temperatures). We prove that below the critical temperature (when the Gibbs-Boltzmann probability measure is singular continuous) the probability measure is supported on the middle-third Cantor set and that further lowering the temperature, the probability measure does not change anymore. This means that, in some sense, the system reaches the ground-state before the zero temperature, indicating that the system "freezes" at a positive temperature.

cond-mat.stat-mech

Large Deviations Properties of Maximum Entropy Markov Chains from Spike Trains

We consider the maximum entropy Markov chain inference approach to characterize the collective statistics of neuronal spike trains, focusing on the statistical properties of the inferred model. We review large deviations techniques useful in this context to describe properties of accuracy and convergence in terms of sampling size. We use these results to study the statistical fluctuation of correlations, distinguishability and irreversibility of maximum entropy Markov chains. We illustrate these applications using simple examples where the large deviation rate function is explicitly obtained for maximum entropy models of relevance in this field.

q-bio.NC

Constant-length random substitutions and Gibbs measures

This work is devoted to the study of processes generated by random substitutions over a finite alphabet. We prove, under mild conditions on the substitution's rule, the existence of a unique process which remains invariant under the substitution, and exhibiting polynomial decay of correlations. For constant-length substitutions, we go further by proving that the invariant state is precisely a Gibbs measure which can be obtained as the projective limit of its natural Markovian approximations. We close the paper with a class of substitutions whose invariant state is the unique Gibbs measure for a hierarchical two-body interaction.

math-ph

Information Entropy Production of Spatio-Temporal Maximum Entropy Distributions

Spiking activity from populations of neurons display causal interactions and memory effects. Therefore, they are expected to show some degree of irreversibility in time. Motivated by the spike train statistics, in this paper we build a framework to quantify the degree of irreversibility of any maximum entropy distribution. Our approach is based on the transfer matrix technique, which enables us to find an homogeneous irreducible Markov chain that shares the same maximum entropy measure. We provide relevant examples in the context of spike train statistics

physics.bio-ph

Unbiased diffusion of Brownian particles on disordered correlated potentials

In this work we study the diffusion of non-interacting overdamped particles, moving on unbiased disordered correlated potentials, subjected to Gaussian white noise. We obtain an exact expression for the diffusion coefficient which allows us to prove that the unbiased diffusion of overdamped particles on a random polymer does not depend on the correlations of the disordered potentials. This universal behavior of the unbiased diffusivity is a direct consequence of the validity of the Einstein relation and the decay of correlations of the random polymer. We test the independence on correlations of the diffusion coefficient for correlated polymers produced by two different stochastic processes, a one-step Markov chain and the expansion-modification system. Within the accuracy of our simulations, we found that the numerically obtained diffusion coefficient for these systems agree with the analytically calculated ones, confirming our predictions.

cond-mat.dis-nn

Normal-to-anomalous diffusion transition in disordered correlated potentials: from the central limit theorem to stable laws

We study the diffusion of an ensemble of overdamped particles sliding over a tilted random poten- tial (produced by the interaction of a particle with a random polymer) with long-range correlations. We found that the diffusion properties of such a system are closely related to the correlation function of the corresponding potential. We model the substrate as a symbolic trajectory of a shift space which enables us to obtain a general formula for the diffusion coefficient when normal diffusion occurs. The total time that the particle takes to travel through n monomers can be seen as an ergodic sum to which we can apply the central limit theorem. The latter can be implemented if the correlations decay fast enough in order for the central limit theorem to be valid. On the other hand, we presume that when the central limit theorem breaks down the system give rise to anomalous diffusion. We give two examples exhibiting a transition from normal to anomalous diffusion due to this mechanism. We also give analytical expressions for the diffusion exponents in both cases by assuming convergence to a stable law. Finally we test our predictions by means of numerical simulations.

cond-mat.dis-nn

Markov Approximations of Gibbs measures for long-range potentials on 1D lattices

We study one-dimensional lattice systems with pair-wise interactions of infinite range. We show projective convergence of Markov measures to the unique equilibrium state. For this purpose we impose a slightly stronger condition than summability of variations on the regularity of the interaction. With our condition we are able to explicitly obtain stretched exponential bounds for the rate of mixing of the equilibrium state. Finally we show convergence for the entropy of the Markov measures to that of the equilibrium state via the convergence of their topological pressure.

math-ph

Fluctuation bounds for chaos plus noise in dynamical systems

We are interested in time series of the form $y_{n} = x_{n} + ξ_{n}$ where ${x_{n}}$ is generated by a chaotic dynamical system and where $ξ_{n}$ models observational noise. Using concentration inequalities, we derive fluctuation bounds for the auto-covariance function, the empirical measure, the kernel density estimator and the correlation dimension evaluated along $y_{0}, ..., y_{n}$, for all $n$. The chaotic systems we consider include for instance the Hénon attractor for Benedicks-Carleson parameters.

nlin.CD