arXiv subjects

Chang Su

Publications and source records attributed to Chang Su.

At least 19 recordsLinked to original sources

arXiv2026

Simulation-to-Real First-Break Segmentation for Efficient Inversion in Musculoskeletal Ultrasound Tomography

Full-waveform inversion (FWI) is a promising strategy for quantitative musculoskeletal ultrasound computed tomography (USCT), but bone-related scattering, attenuation, and signal degradation make it highly sensitive to the accuracy of the initial acoustic-property distributions and prone to cycle skipping. First-arrival traveltimes provide important kinematic information for initial-model construction, yet conventional trace-wise picking is unreliable when arrivals are weak, spatially heterogeneous, or buried in system noise. We propose a learning-assisted reconstruction pipeline that combines segmentation-based first-arrival extraction with hybrid full-waveform inversion (HFWI), which incorporates Rytov-approximation-based traveltime information together with waveform fitting during the early inversion stage. A lightweight 2D U-Net treats the first-arrival trajectory across receiver channels as a first-break segmentation target and exploits its spatial continuity rather than processing each trace independently. To address both limited manual annotations and the simulation-to-real gap, the network is pretrained on task-specific simulations augmented with real system-noise recordings, followed by stage-wise training with progressively increased signal degradation and decoder-only fine-tuning using limited weakly labeled experimental data. The method is evaluated on in vitro phantom, ex vivo bovine-limb, and in vivo human-thigh datasets. Compared with conventional STA/LTA picking, the proposed network yields more spatially coherent first-arrival trajectories, lower mean extraction errors, and processes a full-matrix-capture dataset within seconds. When integrated into HFWI, the extracted arrivals improve initial-model construction and lead to stable subsequent FWI reconstructions, including challenging cases with estimated local first-arrival SNRs below 3 dB.

eess.IV↗

arXiv2026

Coresets Before Score Sets: Evaluation-Unsupervised Prompt Subset Selection for LLM Benchmarks

We study LLM benchmark coreset selection: selecting a small subset of prompts over multiple benchmarks whose induced model scores and rankings approximate those obtained from the full benchmark suite. In evaluation-unsupervised benchmark coreset selection (our approach), the selection algorithm uses no model evaluation outcomes, and operates on a fine granularity by producing subsets of prompts over multiple benchmarks rather than producing a sub-collection of entire benchmarks. We use submodular subset selection, and we develop and evaluate many different submodular functions for this purpose, including determinantal point process (DPP) based approaches, submodular mutual information functions, and facility location-based functions. On a new large-scale suite of 35 heterogeneous benchmarks spanning five different capability categories, 18 frontier LLMs, and over 61K prompts, we find that the facility location (FL) function operating exclusively on inexpensive semantic prompt embeddings preserves LLM scores better than twelve separate score-based and diversity-based baselines, across a range of coreset budgets. Moreover, we show our proposed objective is not limited to the evaluation-unsupervised regime: in the setting where only a handful of whole benchmarks must be selected and a large amount of model scores are available, the same objective matches or outperforms state-of-the-art baselines on the MMLU and MTEB leaderboards, while being substantially cheaper to compute. Together, our results suggest that submodularity, in general, is a strong and reliable tool for benchmark compression.

cs.AI↗

arXiv2026

OmniCoT: A Benchmark for Global and Multi-Step Panoramic Reasoning

Multimodal Large Language Models (MLLMs) have demonstrated promising spatial reasoning capabilities, while these abilities remain underexplored in the emerging visual modality of panoramic imagery. The full 360{\deg}$\times$180{\deg} field of view of panoramas essentially supports complex global multi-step reasoning, which is also the fundamental advantage of panoramas in applications such as embodied intelligence. However, existing panoramic benchmarks largely focus on simplistic queries that rely on local cues or single-/few-step reasoning, thereby ignoring the fundamental advantage of panoramas and failing to fully exploit their potential. To address this gap, we introduce OmniCoT, a panoramic spatial reasoning suite designed to enable MLLMs to use global evidence and perform multi-step inference across viewpoints. It includes OmniCoT-B (6.7K data) for evaluation, which measures both answer accuracy and reasoning quality, OmniCoT-Real (1K data) as a manually annotated real-world subset to quantify the Sim-to-Real gap. For training, OmniCoT-T (14.3K data) is purpose-built with structured stepwise Chain-of-Thought annotations that explicitly link intermediate reasoning steps to panoramic evidence. Based on OmniCoT-T, we introduce OmniCoT-R1 and adopt a two-stage training strategy tailored to the geometrically complex panoramic space, where Supervised Fine-tuning (SFT) anchors reasoning to panoramic evidence (e.g., bearings, proximity) and GRPO penalizes geometrically incoherent paths to consolidate global 360{\deg} spatial consistency. Through OmniCoT, we aim to recalibrate the difficulty of panoramic spatial reasoning to better align with the intrinsic capabilities of panoramic imagery, thereby fostering meaningful progress in this research area.

cs.CV↗

arXiv2026

Hybrid Full Waveform Inversion Assisted by Rytov Approximation for Musculoskeletal Ultrasound Computed Tomography

Ultrasound computed tomography is emerging as a promising safe and accessible modality for soft-tissue medical imaging, with full waveform inversion playing a key role in unlocking its full potential for high-resolution, quantitative reconstructions. Frequency domain full waveform inversion (FDFWI) for reconstructing spatial maps of acoustic properties in the musculoskeletal system is highly sensitive to the quality of low-frequency signals, making the final imaging outcome vulnerable to issues such as inappropriate initial models and strong scatterings related to bones. To address these challenges, we propose a hybrid full waveform inversion (HFWI) algorithm that incorporates a traveltime inversion algorithm based on the generalized Rytov approximation into the FDFWI framework. This hybrid strategy enhances early-stage inversion quality and substantially reduces sensitivity to the initial model, all while maintaining computational efficiency. Importantly, HFWI achieves results comparable to those obtained using well-constructed initial models, without incurring extra computational cost, thus enabling accurate imaging under realistic, bandwidth-limited conditions. In addition, we introduce a near real-time strategy to update first-arrival traveltimes based on forward-scattered phase variations without requiring extra wavefield simulations. Numerical simulations, as well as \textit{in vitro} and \textit{in vivo} experiments confirm the robustness and efficiency of the proposed approach. HFWI also shows promise to extend to more complex scenarios of musculoskeletal parametric reconstruction.

physics.med-ph↗

arXiv2026

Structured Scaling of AI Discovery Across Diverse Scientific Domains

Scientific discovery often requires many cycles of proposing, testing, and refining candidate solutions. Language models can increasingly participate in these loops, but simply generating more attempts does not ensure progress: parallel searches may duplicate one another and iterative refinement may become trapped in poor directions. The central challenge is therefore not only to scale AI-driven discovery, but to structure that scaling so that evaluation signals compound over time. Here we introduce SimpleTES (Simple Test-time Evaluation-driven Scaling), a framework that focuses on the structured scaling of AI discovery loops, organizing evaluator queries across independent trajectories, iterative refinement, local candidate selection, and the selective reuse of evaluated histories. Drawing on structural features of scientific communities, SimpleTES uses a single open-source GPT-OSS model to establish new state-of-the-art solutions across 28 open-ended problems in diverse scientific domains ranging from quantum physics and astronomy to biology, AI, and mathematics. These include a 24.5% reduction in quantum circuit compilation overhead, up to 23% lower propulsive cost for deep-space trajectories, a 2.17x faster lasso-path solver, an 8.5% lower-error whole-brain neural-activity predictor, the fastest reported TriMul kernel, and new mathematical constructions beyond prior human or AI records. We further post-train the model for long-horizon discovery by assigning each attempt the final outcome of the trajectory it helped produce. This improves performance on both training and held-out mathematics problems, further advancing the frontier. Together, these results establish structured scaling as a general mechanism for advancing AI scientific discovery.

cs.LG↗

arXiv2026

Real-Time Coordinated Operation of Off-Grid Wind Powered Multi-Electrolyzer Systems Considering Thermal Dynamics and HTO Safety

Coordinated operation of alkaline water electrolysis (AWE) systems with multiple electrolyzers under fluctuating renewable power input is challenging due to varying power availability and dynamic safety constraints. Moreover, the conventional separation between optimization and control may result in inconsistent decisions across timescales. To address these issues, this paper proposes a two-layer coordinated operation method integrating feedback optimization (FO) with a projection-based safety layer. The FO layer generates real-time reference inputs to improve renewable energy utilization, while the safety layer corrects these inputs to ensure compliance with operational and safety constraints. To explicitly address the safety constraints arising from the inertial dynamics of AWE systems, discrete-time control barrier function theory is incorporated into the safety layer, thereby enhancing safety assurance and online computational tractability. Theoretical analysis establishes the feasibility and effectiveness of the proposed method. Case studies based on annual wind generation data show that the proposed method achieves high energy utilization, maintains safe operation, and demonstrates online applicability, scalability, and robustness.

eess.SY↗

arXiv2026

FS_GPlib: Breaking the Web-Scale Barrier - A Unified Acceleration Framework for Graph Propagation Models

Propagation models are essential for modeling and simulating dynamic processes such as epidemics and information diffusion. However, existing tools struggle to scale to large-scale graphs that emerge across social networks, epidemic networks and so on, due to limited algorithmic efficiency, weak scalability, and high communication overhead. We present FS_GPlib, a unified library that enables efficient, high-fidelity propagation modeling on Web-scale graphs. FS_GPlib introduces a dual-acceleration framework: it combines micro-level synchronous message-passing updates with macro-level batched Monte Carlo simulation, leveraging high-dimensional tensor operations for parallel execution. To further enhance scalability, it supports distributed simulation via a novel target-node-based graph partitioning strategy that minimizes communication overhead while maintaining load balance. Theoretically, we show that under ideal assumptions, the runtime of simulations converges approximately to a constant. Extensive experiments demonstrate up to 35,000 times speedup over standard libraries such as NDlib and execution of a full Monte Carlo simulation on a Web-scale (billion-edge) graph in 11 seconds while maintaining high simulation fidelity. FS_GPlib supports 29 propagation models-including epidemic and opinion dynamics and dynamic network models-and offers a lightweight Python API compatible with mainstream data science ecosystems. By addressing the unique challenges of modeling diffusion and cascades on the Web, FS_GPlib provides a scalable, extensible, and theoretically grounded solution for large-scale propagation analysis in epidemiology, social media analysis, and online network dynamics. Code available at: https://github.com/Allen-Ciel/FS_GPlib.

cs.SI↗

arXiv2026

Helix: Evolutionary Reinforcement Learning for Open-Ended Scientific Problem Solving

Large language models (LLMs) with reasoning abilities have demonstrated growing promise for tackling complex scientific problems. Yet such tasks are inherently domain-specific, unbounded and open-ended, demanding exploration across vast and flexible solution spaces. Existing approaches, whether purely learning-based or reliant on carefully designed workflows, often suffer from limited exploration efficiency and poor generalization. To overcome these challenges, we present HELIX -- a Hierarchical Evolutionary reinforcement Learning framework with In-context eXperiences. HELIX introduces two key novelties: (i) a diverse yet high-quality pool of candidate solutions that broadens exploration through in-context learning, and (ii) reinforcement learning for iterative policy refinement that progressively elevates solution quality. This synergy enables the discovery of more advanced solutions. On the circle packing task, HELIX achieves state-of-the-art result with a sum of radii of 2.63598308 using only a 14B model. Across standard machine learning benchmarks, HELIX further surpasses GPT-4o with a carefully engineered pipeline, delivering an average F1 improvement of 5.95 points on the Adult and Bank Marketing datasets.

cs.LG↗

arXiv2026

Step 3.5 Flash: Open Frontier-Level Intelligence with 11B Active Parameters

We introduce Step 3.5 Flash, a sparse Mixture-of-Experts (MoE) model that bridges frontier-level agentic intelligence and computational efficiency. We focus on what matters most when building agents: sharp reasoning and fast, reliable execution. Step 3.5 Flash pairs a 196B-parameter foundation with 11B active parameters for efficient inference. It is optimized with interleaved 3:1 sliding-window/full attention and Multi-Token Prediction (MTP-3) to reduce the latency and cost of multi-round agentic interactions. To reach frontier-level intelligence, we design a scalable reinforcement learning framework that combines verifiable signals with preference feedback, while remaining stable under large-scale off-policy training, enabling consistent self-improvement across mathematics, code, and tool use. Step 3.5 Flash demonstrates strong performance across agent, coding, and math tasks, achieving 85.4% on IMO-AnswerBench, 86.4% on LiveCodeBench-v6 (2024.08-2025.05), 88.2% on tau2-Bench, 69.0% on BrowseComp (with context management), and 51.0% on Terminal-Bench 2.0, comparable to frontier models such as GPT-5.2 xHigh and Gemini 3.0 Pro. By redefining the efficiency frontier, Step 3.5 Flash provides a high-density foundation for deploying sophisticated agents in real-world industrial environments.

cs.CL↗

arXiv2025

Integrating Epigenetic and Phenotypic Features for Biological Age Estimation in Cancer Patients via Multimodal Learning

Biological age, which may be older or younger than chronological age due to factors such as genetic predisposition, environmental exposures, serves as a meaningful biomarker of aging processes and can inform risk stratification, treatment planning, and survivorship care in cancer patients. We propose EpiCAge, a multimodal framework that integrates epigenetic and phenotypic data to improve biological age prediction. Evaluated on eight internal and four external cancer cohorts, EpiCAge consistently outperforms existing epigenetic and phenotypic age clocks. Our analyses show that EpiCAge identifies biologically relevant markers, and its derived age acceleration is significantly associated with mortality risk. These results highlight EpiCAge as a promising multimodal machine learning tool for biological age assessment in oncology.

q-bio.GN↗

arXiv2025

Training LLMs to be Better Text Embedders through Bidirectional Reconstruction

Large language models (LLMs) have increasingly been explored as powerful text embedders. Existing LLM-based text embedding approaches often leverage the embedding of the final token, typically a reserved special token such as [EOS]. However, these tokens have not been intentionally trained to capture the semantics of the whole context, limiting their capacity as text embeddings, especially for retrieval and re-ranking tasks. We propose to add a new training stage before contrastive learning to enrich the semantics of the final token embedding. This stage employs bidirectional generative reconstruction tasks, namely EBQ2D (Embedding-Based Query-to-Document) and EBD2Q (Embedding-Based Document-to-Query), which interleave to anchor the [EOS] embedding and reconstruct either side of Query-Document pairs. Experimental results demonstrate that our additional training stage significantly improves LLM performance on the Massive Text Embedding Benchmark (MTEB), achieving new state-of-the-art results across different LLM base models and scales.

cs.CL↗

arXiv2025

Ultrasound Tomography of Musculoskeletal Tissues with Generative Neural Physics

Ultrasound Tomography (UT) is a radiation-free, high-resolution modality, but remains limited for musculoskeletal imaging due to the high computational cost and instability of full-waveform inversion in strongly scattering media. We propose a generative neural physics framework that couples generative networks with physics-informed neural simulation for fast, high-fidelity 3D UT. By learning a compact surrogate of ultrasonic wave propagation from a limited set of cross-modality images, our method merges the accuracy of wave modeling with the efficiency and stability of deep learning. This enables accurate quantitative imaging of in vivo musculoskeletal tissues, producing spatial maps of acoustic properties beyond reflection-mode images. On synthetic and in vivo data of breasts, arms, and legs, we reconstruct 3D maps of tissue parameters in under ten minutes, with sensitivity to acoustic variations in musculoskeletal tissues and resolution comparable to MRI. By overcoming computational bottlenecks in strongly scattering regimes, this approach demonstrates the feasibility of quantitative UT for musculoskeletal imaging and advances its development toward future routine clinical use.

cs.CV↗

arXiv2025

X-MoGen: Unified Motion Generation across Humans and Animals

Text-driven motion generation has attracted increasing attention due to its broad applications in virtual reality, animation, and robotics. While existing methods typically model human and animal motion separately, a joint cross-species approach offers key advantages, such as a unified representation and improved generalization. However, morphological differences across species remain a key challenge, often compromising motion plausibility. To address this, we propose X-MoGen, the first unified framework for cross-species text-driven motion generation covering both humans and animals. X-MoGen adopts a two-stage architecture. First, a conditional graph variational autoencoder learns canonical T-pose priors, while an autoencoder encodes motion into a shared latent space regularized by morphological loss. In the second stage, we perform masked motion modeling to generate motion embeddings conditioned on textual descriptions. During training, a morphological consistency module is employed to promote skeletal plausibility across species. To support unified modeling, we construct UniMo4D, a large-scale dataset of 115 species and 119k motion sequences, which integrates human and animal motions under a shared skeletal topology for joint training. Extensive experiments on UniMo4D demonstrate that X-MoGen outperforms state-of-the-art methods on both seen and unseen species.

cs.CV↗

arXiv2025

Emotion Knowledge Enhancement for Vision Large Language Models: A Self-Verification Approach for High-Quality Emotion Instruction Data Generation

Facial emotion perception in the vision large language model (VLLM) is crucial for achieving natural human-machine interaction. However, creating high-quality annotations for both coarse- and fine-grained facial emotion analysis demands costly expertise. The lack of such high-quality instruction data limits the performance of VLLMs in facial emotion perception. To address this, we propose a self-verification approach with emotion knowledge enhancement (SEKE), which generates high-quality instruction data for multi-grained emotion analysis cost-effectively using closed-source VLLM. This approach integrates prior human knowledge to VLLM inference, guided by the inherent correlations between three grained levels of emotion descriptions, i.e., discrete expression, valence-arousal, and action unit, to reliably generate comprehensive annotations. A self-verification strategy with Uncertainty-Aware Monte Carlo sampling (SV-UAMC) is further embedded to efficiently extract more accurate VLLM predictions, further improving annotation reliability. Consequently, we construct a facial emotion instruction dataset (FEID) containing three comprehensive descriptions, which provides coarse- and fine-grained emotional information for effective model training. Additionally, we introduce a facial emotion analysis benchmark (FEAB) to measure the VLLM's corresponding ability. Our method significantly outperforms state-of-the-art methods on three downstream facial emotion analysis tasks.

cs.LG↗

arXiv2025

Under-Sampled High-Dimensional Data Recovery via Symbiotic Multi-Prior Tensor Reconstruction

The advancement of sensing technology has driven the widespread application of high-dimensional data. However, issues such as missing entries during acquisition and transmission negatively impact the accuracy of subsequent tasks. Tensor reconstruction aims to recover the underlying complete data from under-sampled observed data by exploring prior information in high-dimensional data. However, due to insufficient exploration, reconstruction methods still face challenges when sampling rate is extremely low. This work proposes a tensor reconstruction method integrating multiple priors to comprehensively exploit the inherent structure of the data. Specifically, the method combines learnable tensor decomposition to enforce low-rank constraints of the reconstructed data, a pre-trained convolutional neural network for smoothing and denoising, and block-matching and 3D filtering regularization to enhance the non-local similarity in the reconstructed data. An alternating direction method of the multipliers algorithm is designed to decompose the resulting optimization problem into three subproblems for efficient resolution. Extensive experiments on color images, hyperspectral images, and grayscale videos datasets demonstrate the superiority of our method in extreme cases as compared with state-of-the-art methods.

eess.IV↗

arXiv2025

SCOPE-DTI: Semi-Inductive Dataset Construction and Framework Optimization for Practical Usability Enhancement in Deep Learning-Based Drug Target Interaction Prediction

Deep learning-based drug-target interaction (DTI) prediction methods have demonstrated strong performance; however, real-world applicability remains constrained by limited data diversity and modeling complexity. To address these challenges, we propose SCOPE-DTI, a unified framework combining a large-scale, balanced semi-inductive human DTI dataset with advanced deep learning modeling. Constructed from 13 public repositories, the SCOPE dataset expands data volume by up to 100-fold compared to common benchmarks such as the Human dataset. The SCOPE model integrates three-dimensional protein and compound representations, graph neural networks, and bilinear attention mechanisms to effectively capture cross domain interaction patterns, significantly outperforming state-of-the-art methods across various DTI prediction tasks. Additionally, SCOPE-DTI provides a user-friendly interface and database. We further validate its effectiveness by experimentally identifying anticancer targets of Ginsenoside Rh1. By offering comprehensive data, advanced modeling, and accessible tools, SCOPE-DTI accelerates drug discovery research.

cs.LG↗

arXiv2025

R1-T1: Fully Incentivizing Translation Capability in LLMs via Reasoning Learning

Despite recent breakthroughs in reasoning-enhanced large language models (LLMs) like DeepSeek-R1, incorporating inference-time reasoning into machine translation (MT), where human translators naturally employ structured, multi-layered reasoning chain-of-thoughts (CoTs), is yet underexplored. Existing methods either design a fixed CoT tailored for a specific MT sub-task (e.g., literature translation), or rely on synthesizing CoTs unaligned with humans and supervised fine-tuning (SFT) prone to overfitting, limiting their adaptability to diverse translation scenarios. This paper introduces R1-Translator (R1-T1), a novel framework to achieve inference-time reasoning for general MT via reinforcement learning (RL) with human-aligned CoTs comprising six common patterns. Our approach pioneers three innovations: (1) extending reasoning-based translation to broader MT scenarios (e.g., multilingual MT, domain MT) unseen in the training phase; (2) formalizing six expert-curated CoT templates that mirror hybrid human strategies like context-aware paraphrasing and back translation; and (3) enabling self-evolving CoT discovery through RL. Both human and automatic evaluation results indicate a steady translation performance improvement in a total of 10+ languages and 40+ translation directions on Flores-101 test set and four domain-specific MT tasks, especially on the languages unseen from training.

cs.CL↗

arXiv2024

Model Predictive Control Enabled UAV Trajectory Optimization and Secure Resource Allocation

In this paper, we investigate a secure communication architecture based on unmanned aerial vehicle (UAV), which enhances the security performance of the communication system through UAV trajectory optimization. We formulate a control problem of minimizing the UAV flight path and power consumption while maximizing secure communication rate over infinite horizon by jointly optimizing UAV trajectory, transmit beamforming vector, and artificial noise (AN) vector. Given the non-uniqueness of optimization objective and significant coupling of the optimization variables, the problem is a non-convex optimization problem which is difficult to solve directly. To address this complex issue, an alternating-iteration technique is employed to decouple the optimization variables. Specifically, the problem is divided into three subproblems, i.e., UAV trajectory, transmit beamforming vector, and AN vector, which are solved alternately. Additionally, considering the susceptibility of UAV trajectory to disturbances, the model predictive control (MPC) approach is applied to obtain UAV trajectory and enhance the system robustness. Numerical results demonstrate the superiority of the proposed optimization algorithm in maintaining accurate UAV trajectory and high secure communication rate compared with other benchmark schemes.

eess.SP↗