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Chaowei Wu

Publications and source records attributed to Chaowei Wu.

4 recordsLinked to original sources

SideAge-RiskNet: Predicted Mammographic-Age Features for Future Breast Cancer Risk and Laterality Prediction

Whether breast-specific mammographic aging provides information beyond chronological age for future cancer prediction remains unclear. We propose SideAge-RiskNet, a framework integrating predicted mammographic-age features with breast-specific representations for multi-year breast cancer risk and conditional laterality prediction. A side-aware DenseNet121 trained on never-cancer reference examinations estimates left and right breast ages. Age-adjusted residuals and bilateral age descriptors are subsequently fused with corresponding image representations, while clinical variables contribute through an image--clinical risk branch. The framework jointly predicts cumulative cancer risk over 1--5 years and the subsequently affected breast among unilateral cancer cases. Across 4,480 EMBED and 248 external examinations, pre-cancer scans demonstrated pronounced bilateral age asymmetry. SideAge-RiskNet established state-of-the-art performance in 1--5-year risk assessment over Mirai and AsymMirai with mean risk AUROCs of 81.73% on EMBED and 72.83% on CSMC. Furthermore, it enabled conditional cancer laterality prediction, achieving AUROCs of 73.26% and 82.53%, respectively. This demonstrates the critical utility of bilateral aging phenotypes in localized breast cancer risk surveillance.

eess.IV↗

FD-AA: A Lightweight Focal-Diffuse And Attenuation-Aware Head for Incidental Abdominal Abnormality Detection in Chest CT

Routine chest CT captures upper-abdominal structures that may contain clinically relevant incidental abnormalities. Detecting these findings requires feature extraction from organs with different spatial extents and attenuation patterns. We propose FD-AA, a lightweight organ-aware classification head adaptable for frozen 3-D CT encoders. Within each organ, an attenuation-aware module preserves sparse focal evidence, while masked generalized-mean pooling captures diffuse anomaly patterns. In seven abdominal organs, FD-AA with Pillar-0 achieved state-of-the-art (SOTA) performance in both the CT-RATE test set (AUC = 0.798) and the external RAD-ChestCT dataset (AUC = 0.713). More specifically, FD-AA improved macro AUC/AP from 0.763/0.346 to 0.798/0.405 over direct classification using frozen Pillar-0 only (p = 0.034/0.016). Such performance gain generalizes across multiple frozen encoders (AUC improvement on MedicalNet +9.8%, CT-CLIP +14.7%, ResNet +3.7%), demonstrating the effectiveness of FD-AA across different feature representations. These results support the effectiveness of integrating focal-diffuse aggregation with explicit HU evidence for incidental abdominal abnormality detection.

cs.CV↗

Instance-Guided Report Anchoring for Text-Free 3D Abnormality Segmentation in Chest CT

Accurate 3D abnormality segmentation in chest CT requires dense spatial supervision, but obtaining expert voxel-level labels is costly. Radiology reports, however, are routinely generated during clinical interpretation and contain instance-specific descriptions that can provide additional guidance without new dense annotation. Existing vision-language grounding methods typically require report-derived findings at inference, making localization dependent on paired text and limiting each forward pass to a queried finding. We propose Instance-Guided Report Anchoring (IGRA), a model-agnostic module that preserves the correspondence between each annotated abnormality instance and the report finding that describes it. IGRA pools each instance representation and anchors it to the corresponding finding embedding during training; all text-related components are discarded at inference. We further reformulate free-text grounding on ReXGroundingCT as multi-label volumetric segmentation by merging same-category instances, allowing all abnormality categories to be predicted in one image-only forward pass. IGRA improves Dice by 22.5% over the strongest image-only baseline (30.93 vs. 25.25) and is comparable to VoxTell on the single-finding subset (30.29 vs. 30.43). Applied unchanged to four standard 3D segmentation backbones, IGRA improves Dice and hit rate across all architectures. Zero-shot evaluation on LIDC-IDRI, PleThora, and a private in-house dataset further shows consistent gains over image-only baselines.

cs.CV↗

AgentLTV: An Agent-Based Unified Search-and-Evolution Framework for Automated Lifetime Value Prediction

Lifetime Value (LTV) prediction is critical in advertising, recommender systems, and e-commerce. In practice, LTV data patterns vary across decision scenarios. As a result, practitioners often build complex, scenario-specific pipelines and iterate over feature processing, objective design, and tuning. This process is expensive and hard to transfer. We propose AgentLTV, an agent-based unified search-and-evolution framework for automated LTV modeling. AgentLTV treats each candidate solution as an {executable pipeline program}. LLM-driven agents generate code, run and repair pipelines, and analyze execution feedback. Two decision agents coordinate a two-stage search. The Monte Carlo Tree Search (MCTS) stage explores a broad space of modeling choices under a fixed budget, guided by the Polynomial Upper Confidence bounds for Trees criterion and a Pareto-aware multi-metric value function. The Evolutionary Algorithm (EA) stage refines the best MCTS program via island-based evolution with crossover, mutation, and migration. Experiments on a large-scale proprietary dataset and a public benchmark show that AgentLTV consistently discovers strong models across ranking and error metrics. Online bucket-level analysis further indicates improved ranking consistency and value calibration, especially for high-value and negative-LTV segments. We summarize practitioner-oriented takeaways: use MCTS for rapid adaptation to new data patterns, use EA for stable refinement, and validate deployment readiness with bucket-level ranking and calibration diagnostics. The proposed AgentLTV has been successfully deployed online.

cs.LG↗