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Cheems Wang

Publications and source records attributed to Cheems Wang.

10 recordsLinked to original sources

SpaCellAgent: A Self-Evolving LLM-Based Multi-Agent Framework for Trajectory Analysis

Spatial and Single-cell transcriptomics are transformative in deciphering cellular dynamics. As the fundamental paradigm for reconstructing cell developmental paths, trajectory inference (TI) is critical. However, existing methods require extensive manual intervention and proficiency in heterogeneous tools, posing a significant barrier to efficient TI analysis. To bridge this gap, we propose SpaCellAgent, an autonomous large language model (LLM) multi-agent framework that automates end-to-end spatiotemporal analysis and narrative generation. SpaCellAgent utilizes a multi-agent architecture for strategic workflow planning, a dynamic tool-orchestration engine for adaptive algorithm selection, and a self-evolution module that iteratively refines performance through feedback. We evaluate SpaCellAgent on six heterogeneous datasets encompassing complex temporal developmental trajectories, diverse sequencing platforms, and spatially-resolved tissue architectures. SpaCellAgent consistently demonstrates over 40\% improvement in analytical efficiency while maintaining expert-aligned performance. By converting natural language specifications into optimized analytical workflows and fully automating the pipeline, SpaCellAgent democratizes advanced spatiotemporal modeling and establishes a scalable, agent-driven paradigm for computational biology. The code and materials are available at https://github.com/LittleXH-shw/SpaCellAgent.

cs.AI

StrLoRA: Towards Streaming Continual Visual Instruction Tuning for MLLMs

Continual Visual Instruction Tuning (CVIT) enables Multimodal Large Language Models to incrementally acquire new abilities. However, existing CVIT methods operate under a restrictive task-incremental setting, where each training phase corresponds to a single, predefined task. This does not reflect real-world conditions, where data arrives as a continuous stream of interleaved and dynamically evolving tasks. To bridge this gap, we introduce Streaming CVIT (StrCVIT), a more general and realistic setting where models learn from a stream of data chunks containing a dynamic mixture of tasks. In StrCVIT, a model must simultaneously acquire new abilities, reinforce recurring abilities, and mitigate forgetting. Existing CVIT methods fail here as they cannot reliably distinguish or adapt to the heterogeneous task samples within each chunk. We therefore propose StrLoRA, a regularized two-stage expert routing framework. StrLoRA first performs task-aware expert selection using the textual instruction to activate a sparse subset of relevant experts, reducing cross-task interference. It then applies token-wise expert weighting within this subset, where contribution weights are computed via cross-modal attention between local visual tokens and the global instruction representation. To maintain stability across the non-stationary stream, a routing-stability regularization aligns current routing distributions with a historical exponential moving average reference. Extensive experiments on a newly developed StrCVIT benchmark show that StrLoRA substantially outperforms existing methods, effectively enhancing model's abilities from continuously evolving data streams. The code is available at https://github.com/chanceche/StrCVIT.

cs.CV

Limited Reasoning Space: The cage of long-horizon reasoning in LLMs

The test-time compute strategy, such as Chain-of-Thought (CoT), has significantly enhanced the ability of large language models to solve complex tasks like logical reasoning. However, empirical studies indicate that simply increasing the compute budget can sometimes lead to a collapse in test-time performance when employing typical task decomposition strategies such as CoT. This work hypothesizes that reasoning failures with larger compute budgets stem from static planning methods, which hardly perceive the intrinsic boundaries of LLM reasoning. We term it as the Limited Reasoning Space hypothesis and perform theoretical analysis through the lens of a non-autonomous stochastic dynamical system. This insight suggests that there is an optimal range for compute budgets; over-planning can lead to redundant feedback and may even impair reasoning capabilities. To exploit the compute-scaling benefits and suppress over-planning, this work proposes Halo, a model predictive control framework for LLM planning. Halo is designed for long-horizon tasks with reason-based planning and crafts an entropy-driven dual controller, which adopts a Measure-then-Plan strategy to achieve controllable reasoning. Experimental results demonstrate that Halo outperforms static baselines on complex long-horizon tasks by dynamically regulating planning at the reasoning boundary.

cs.AI

HOB: A Holistically Optimized Bidding Strategy under Heterogeneous Bidding Environments

Optimizing a single advertising campaign across heterogeneous channels is a central challenge in industrial autobidding. Auction mechanisms vary across channels in ranking rules (pure eCPM vs. UE-augmented scoring), pricing formats (first- vs. second-price), and bidding conventions (uniform vs. non-uniform), while advertisers impose shared campaign-level constraints. We propose HOB, which makes marginal cost (MC) computable and alignable across heterogeneous channels, especially for first-price auctions (FPA) with organic-paid coexistence, where existing bidding formulations do not yield a practical aligned MC form. At the global level, HOB derives channel-specific MC forms and coordinates disparate channels through a shared MC target. At the local level, HOB models free-win probability and winning-price uncertainty with a zero-inflated exponential distribution, yielding an efficient surplus-optimal bidding strategy for non-uniform first-price auctions. We show that any interior optimum satisfies MC equalization across channels. Experiments on a controlled offline benchmark, industrial log replay, and large-scale online A/B tests demonstrate that HOB consistently delivers significant performance gains. Deployed on a large-scale commercial DSP, HOB delivers a 3.0% lift in GMV while maintaining return on advertising spend (ROAS) constraints.

cs.GT

Gains: Fine-grained Federated Domain Adaptation in Open Set

Conventional federated learning (FL) assumes a closed world with a fixed total number of clients. In contrast, new clients continuously join the FL process in real-world scenarios, introducing new knowledge. This raises two critical demands: detecting new knowledge, i.e., knowledge discovery, and integrating it into the global model, i.e., knowledge adaptation. Existing research focuses on coarse-grained knowledge discovery, and often sacrifices source domain performance and adaptation efficiency. To this end, we propose a fine-grained federated domain adaptation approach in open set (Gains). Gains splits the model into an encoder and a classifier, empirically revealing features extracted by the encoder are sensitive to domain shifts while classifier parameters are sensitive to class increments. Based on this, we develop fine-grained knowledge discovery and contribution-driven aggregation techniques to identify and incorporate new knowledge. Additionally, an anti-forgetting mechanism is designed to preserve source domain performance, ensuring balanced adaptation. Experimental results on multi-domain datasets across three typical data-shift scenarios demonstrate that Gains significantly outperforms other baselines in performance for both source-domain and target-domain clients. Code is available at: https://github.com/Zhong-Zhengyi/Gains.

cs.LG

Latent Reward: LLM-Empowered Credit Assignment in Episodic Reinforcement Learning

Reinforcement learning (RL) often encounters delayed and sparse feedback in real-world applications, even with only episodic rewards. Previous approaches have made some progress in reward redistribution for credit assignment but still face challenges, including training difficulties due to redundancy and ambiguous attributions stemming from overlooking the multifaceted nature of mission performance evaluation. Hopefully, Large Language Model (LLM) encompasses fruitful decision-making knowledge and provides a plausible tool for reward redistribution. Even so, deploying LLM in this case is non-trivial due to the misalignment between linguistic knowledge and the symbolic form requirement, together with inherent randomness and hallucinations in inference. To tackle these issues, we introduce LaRe, a novel LLM-empowered symbolic-based decision-making framework, to improve credit assignment. Key to LaRe is the concept of the Latent Reward, which works as a multi-dimensional performance evaluation, enabling more interpretable goal attainment from various perspectives and facilitating more effective reward redistribution. We examine that semantically generated code from LLM can bridge linguistic knowledge and symbolic latent rewards, as it is executable for symbolic objects. Meanwhile, we design latent reward self-verification to increase the stability and reliability of LLM inference. Theoretically, reward-irrelevant redundancy elimination in the latent reward benefits RL performance from more accurate reward estimation. Extensive experimental results witness that LaRe (i) achieves superior temporal credit assignment to SOTA methods, (ii) excels in allocating contributions among multiple agents, and (iii) outperforms policies trained with ground truth rewards for certain tasks.

cs.LG

Stop Wandering, Find the Keys: LLMs Discriminate Key States for Efficient Multi-Agent Exploration

With expansive state-action spaces, efficient multi-agent exploration remains a longstanding challenge in reinforcement learning. Although pursuing novelty, diversity, or uncertainty attracts increasing attention, redundant efforts brought by exploration without proper guidance choices poses a practical issue for the community. This paper introduces a systematic approach, termed LEMAE, choosing to channel informative task-relevant guidance from a knowledgeable Large Language Model (LLM) for Efficient Multi-Agent Exploration. Specifically, we ground linguistic knowledge from LLM into symbolic key states, that are critical for task fulfillment, in a discriminative manner at low LLM inference costs. To unleash the power of key states, we design Subspace-based Hindsight Intrinsic Reward (SHIR) to guide agents toward key states by increasing reward density. Additionally, we build the Key State Memory Tree (KSMT) to track transitions between key states in a specific task for organized exploration. Benefiting from diminishing redundant explorations, LEMAE outperforms existing SOTA approaches on the challenging benchmarks (e.g., SMAC and MPE) by a large margin, achieving a 10x acceleration in certain scenarios.

cs.AI

Robust Fast Adaptation from Adversarially Explicit Task Distribution Generation

Meta-learning is a practical learning paradigm to transfer skills across tasks from a few examples. Nevertheless, the existence of task distribution shifts tends to weaken meta-learners' generalization capability, particularly when the training task distribution is naively hand-crafted or based on simple priors that fail to cover critical scenarios sufficiently. Here, we consider explicitly generative modeling task distributions placed over task identifiers and propose robustifying fast adaptation from adversarial training. Our approach, which can be interpreted as a model of a Stackelberg game, not only uncovers the task structure during problem-solving from an explicit generative model but also theoretically increases the adaptation robustness in worst cases. This work has practical implications, particularly in dealing with task distribution shifts in meta-learning, and contributes to theoretical insights in the field. Our method demonstrates its robustness in the presence of task subpopulation shifts and improved performance over SOTA baselines in extensive experiments. The code is available at the project site https://sites.google.com/view/ar-metalearn.

cs.LG

Reducing Fine-Tuning Memory Overhead by Approximate and Memory-Sharing Backpropagation

Fine-tuning pretrained large models to downstream tasks is an important problem, which however suffers from huge memory overhead due to large-scale parameters. This work strives to reduce memory overhead in fine-tuning from perspectives of activation function and layer normalization. To this end, we propose the Approximate Backpropagation (Approx-BP) theory, which provides the theoretical feasibility of decoupling the forward and backward passes. We apply our Approx-BP theory to backpropagation training and derive memory-efficient alternatives of GELU and SiLU activation functions, which use derivative functions of ReLUs in the backward pass while keeping their forward pass unchanged. In addition, we introduce a Memory-Sharing Backpropagation strategy, which enables the activation memory to be shared by two adjacent layers, thereby removing activation memory usage redundancy. Our method neither induces extra computation nor reduces training efficiency. We conduct extensive experiments with pretrained vision and language models, and the results demonstrate that our proposal can reduce up to $\sim$$30\%$ of the peak memory usage. Our code is released at https://github.com/yyyyychen/LowMemoryBP.

cs.LG

GO4Align: Group Optimization for Multi-Task Alignment

This paper proposes \textit{GO4Align}, a multi-task optimization approach that tackles task imbalance by explicitly aligning the optimization across tasks. To achieve this, we design an adaptive group risk minimization strategy, comprising two techniques in implementation: (i) dynamical group assignment, which clusters similar tasks based on task interactions; (ii) risk-guided group indicators, which exploit consistent task correlations with risk information from previous iterations. Comprehensive experimental results on diverse benchmarks demonstrate our method's performance superiority with even lower computational costs.

cs.LG