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Chenda Duan

Publications and source records attributed to Chenda Duan.

13 recordsLinked to original sources

PANINI-DR: Controlled Deep Research through Generative Semantic Workspaces

Deep research requires connecting multiple steps of search, reasoning, and computation, with intermediate findings guiding what to investigate next. As investigations grow, agents must maintain research state across model calls and check findings before errors propagate into subsequent work. We introduce PANINI-DR, a multi-agent harness that separates coordination of the overall investigation from the research and verification of individual subquestions. A shared workspace, built on the Generative Semantic Workspace representation, records subquestions, their dependencies, findings, and supporting evidence. Researchers investigate individual subquestions, while a separate verification agent checks proposed answers against those subquestions and their evidence. Verification feedback guides further investigation, and recorded findings inform subsequent assignments. We evaluate PANINI-DR on BrowseComp-Plus, FRAMES, and MoNaCo against seven state-of-the-art deep-research harnesses, all using a shared language-model backbone and frozen corpora. PANINI-DR achieves the strongest average performance across the three benchmarks. On BrowseComp-Plus, it achieves 73.3% accuracy, outperforming the next-best harness by 16.0 points. Its advantage is strongest on hard questions, where it answers nearly twice as many as the next-best harness. Ablations further show that structured planning and persistent state improve performance, as does checking each finding against its cited evidence before it is reused. Because a model can answer correctly from memory alone, we also analyze the evidence retained by each harness. PANINI-DR achieves the highest answer recoverability from saved evidence on all three benchmarks, while complementary claim-support audits show stronger evidence-backed answers. Accounting for this evidence changes how harnesses compare and further strengthens PANINI-DR's advantage.

cs.CL↗

PHASE: A Physiology-Guided Hierarchical Foundation Model for Intracranial EEG

Clinicians and neuroscientists have long analyzed intracranial electroencephalography (iEEG) through directly measurable physiological characteristics, which carry much of the information that downstream tasks depend on. Recent iEEG foundation models learn by reconstructing or predicting their inputs, which leaves the retention of these characteristics implicit. They are also evaluated mainly on cognitive decoding and a narrow clinical task, i.e., seizure detection. On a broad, clinically relevant benchmark such as Omni-iEEG, they remain below task-specific models when used frozen. We introduce PHASE, a physiology-guided foundation model that makes these characteristics explicit learning targets, pairing them with masked latent prediction in a temporal stage (PHASE-T) within each channel and a spatiotemporal stage (PHASE-ST) across synchronized channels. PHASE is pretrained on heterogeneous recordings from 222 participants at nine clinical sites. On all five Omni-iEEG clinical tasks, frozen PHASE-T outperforms every evaluated foundation model by up to 31\%, and fine-tuned PHASE-T surpasses the task-specific models, setting a new state of the art. PHASE-T benefits from physiological supervision, outperforming variants trained with latent prediction alone or auxiliary waveform reconstruction on every task in matched ablations. PHASE-T generalizes to unseen institutions, outperforming the compared models with few or no local labels. PHASE-ST further improves seizure-onset-zone identification over PHASE-T and, when frozen, decodes sound volume and pitch on BrainTreebank better than published models. Beyond task performance, PHASE learns to encapsulate the physiological characteristics clinicians recognize, from seizure onset and its propagation to anatomical region identity, even though its pretraining contains no ictal recordings or anatomical labels.

cs.LG↗

MERID: Multimodal Exploration via Recursive Self-Improvement Agents for Major Depression Analysis

Major depressive disorder (MDD) severely impacts daily activities and quality of life. Detecting MDD involves multimodal data, such as interview recordings and sensor measurements. This is particularly challenging, as these heterogeneous modalities often demand distinct, customized prediction pipelines. Existing efforts to address this challenge have explored both manually engineered multimodal architectures and agent-assisted pipeline development. Despite their progress, it remains challenging to autonomously revise pipelines based on experimental feedback and carry verified improvements forward into subsequent designs. To this end, we propose Multimodal Exploration via Recursive Self-Improvement Agents for Major Depression Analysis (MERID). The framework develops depression pipelines through experience-based recursive self-improvement (RSI). Grounded State Construction (GSC) grounds experience by aligning multimodal records with subject-level depression targets. Coupled Pipeline Exploration (CPE) jointly modifies representations, fusion, and predictors to build successor pipelines for classification and severity estimation. Evidence-Guided Evolution (EGE) guides revisions through feedback and verifies gains under uncertainty in small depression cohorts before inheritance. Extensive experiments on depression benchmarks show that MERID achieves the best results on multiple tasks compared with multimodal and agent-based baselines. Further analysis highlights the value of acoustic and linguistic cues for depression detection. Our code is available at https://github.com/DiscoAILab/MERID

cs.AI↗

Omni-iEEG Planner: an open-source Python platform integrating multimodal neuroimaging and intracranial EEG data for epilepsy surgery research

Multimodal intracranial EEG (iEEG) research for epilepsy surgery combines anatomical and functional imaging, implanted electrode locations, interictal biomarkers, and functional mapping--outputs produced by different applications and reconciled by hand before they can be viewed on the same anatomy. Omni-iEEG Planner is an open-source Python platform that brings these inputs into one patient coordinate frame for research data analysis. The workflow starts from the preoperative T1-weighted MRI, from which FreeSurfer provides the cortical surface and anatomical labels; CT, PET and diffusion MRI are then co-registered to that reference, electrode contacts are detected automatically on the postimplantation CT and reviewed by the analyst, and tractography is reconstructed within the application. Channel-indexed results computed outside the platform, such as high-frequency oscillation counts from pyHFO or time-resolved gamma responses, are projected onto the contacts and the cortical surface with their source units preserved, and interictal and functional evidence remain separate layers. We describe the design and demonstrate representative workflows on de-identified patient data. The platform is not proposed as a method for every laboratory; it is a worked example of how one research group combined multimodal integration with an AI-assisted iEEG analysis tool, pyHFO, in a single open environment that others can adapt to their own pipelines. The design will accommodate further evidence types--model-derived contact scores, virtual implantation and hypothetical resection studies, group-level analyses--as they are implemented. The software is released under the MIT license for research and educational use, not clinical decision-making.

physics.med-ph↗

Occamy-1.0: Open Pareto-frontier 35B Intelligence for Co-work

Co-work agents execute complex workflows that combine information gathering, tool use, coding, and file manipulation across many model invocations. Because cost and latency accumulate over the full episode, their practical value depends not only on peak capability but also on how efficiently that capability is delivered. Yet many steps in everyday work emphasize state tracking, coordination, recovery, and follow-through rather than frontier-scale reasoning. We present Occamy-1.0, a cost-efficient co-work model obtained by further training the post-trained Qwen3.6-35B-A3B checkpoint. We construct execution-grounded data and environments, capture replayable long-horizon trajectories across multiple harnesses, and use staged post-training to develop and consolidate complementary execution capabilities. Across a broad suite of co-work benchmarks, Occamy-1.0 is consistently among the strongest comparably sized models and remains competitive with substantially larger frontier systems on several tasks. Under our stated evaluation and pricing protocol, its aggregate performance across four representative benchmarks places it at the low-cost knee of the observed cost--performance Pareto frontier. Supporting evaluations in tool calling, coding, and instruction following further show that this specialization preserves broad agentic capability. We release the model weights and a subset of the training data to support research on practical co-work agents and agentic post-training.

cs.AI↗

Omni-iEEG: A Large-Scale, Comprehensive iEEG Dataset and Benchmark for Epilepsy Research

Epilepsy affects over 50 million people worldwide, and one-third of patients suffer drug-resistant seizures where surgery offers the best chance of seizure freedom. Accurate localization of the epileptogenic zone (EZ) relies on intracranial EEG (iEEG). Clinical workflows, however, remain constrained by labor-intensive manual review. At the same time, existing data-driven approaches are typically developed on single-center datasets that are inconsistent in format and metadata, lack standardized benchmarks, and rarely release pathological event annotations, creating barriers to reproducibility, cross-center validation, and clinical relevance. With extensive efforts to reconcile heterogeneous iEEG formats, metadata, and recordings across publicly available sources, we present $\textbf{Omni-iEEG}$, a large-scale, pre-surgical iEEG resource comprising $\textbf{302 patients}$ and $\textbf{178 hours}$ of high-resolution recordings. The dataset includes harmonized clinical metadata such as seizure onset zones, resections, and surgical outcomes, all validated by board-certified epileptologists. In addition, Omni-iEEG provides over 36K expert-validated annotations of pathological events, enabling robust biomarker studies. Omni-iEEG serves as a bridge between machine learning and epilepsy research. It defines clinically meaningful tasks with unified evaluation metrics grounded in clinical priors, enabling systematic evaluation of models in clinically relevant settings. Beyond benchmarking, we demonstrate the potential of end-to-end modeling on long iEEG segments and highlight the transferability of representations pretrained on non-neurophysiological domains. Together, these contributions establish Omni-iEEG as a foundation for reproducible, generalizable, and clinically translatable epilepsy research. The project page with dataset and code links is available at omni-ieeg.github.io/omni-ieeg.

cs.LG↗

Beyond Fact Retrieval: Episodic Memory for RAG with Generative Semantic Workspaces

Large Language Models (LLMs) face fundamental challenges in long-context reasoning: many documents exceed their finite context windows, while performance on texts that do fit degrades with sequence length, necessitating their augmentation with external memory frameworks. Current solutions, which have evolved from retrieval using semantic embeddings to more sophisticated structured knowledge graphs representations for improved sense-making and associativity, are tailored for fact-based retrieval and fail to build the space-time-anchored narrative representations required for tracking entities through episodic events. To bridge this gap, we propose the \textbf{Generative Semantic Workspace} (GSW), a neuro-inspired generative memory framework that builds structured, interpretable representations of evolving situations, enabling LLMs to reason over evolving roles, actions, and spatiotemporal contexts. Our framework comprises an \textit{Operator}, which maps incoming observations to intermediate semantic structures, and a \textit{Reconciler}, which integrates these into a persistent workspace that enforces temporal, spatial, and logical coherence. On the Episodic Memory Benchmark (EpBench) \cite{huet_episodic_2025} comprising corpora ranging from 100k to 1M tokens in length, GSW outperforms existing RAG based baselines by up to \textbf{20\%}. Furthermore, GSW is highly efficient, reducing query-time context tokens by \textbf{51\%} compared to the next most token-efficient baseline, reducing inference time costs considerably. More broadly, GSW offers a concrete blueprint for endowing LLMs with human-like episodic memory, paving the way for more capable agents that can reason over long horizons. Code is available at https://github.com/roychowdhuryresearch/gsw-memory.

cs.AI↗

Panini: Continual Learning in Token Space via Structured Memory

Language models are increasingly used to reason over content they were not trained on, such as new documents, evolving knowledge, and user-specific data. A common approach is retrieval-augmented generation (RAG), which stores verbatim documents externally (as chunks) and retrieves only a relevant subset at inference time for an LLM to reason over. However, this results in inefficient usage of test-time compute (LLM repeatedly reasons over the same documents); moreover, chunk retrieval can inject irrelevant context that increases unsupported generation. We propose a human-like non-parametric continual learning framework, where the base model remains fixed, and learning occurs by integrating each new experience into an external semantic memory state that accumulates and consolidates itself continually. We present Panini, which realizes this by representing documents as Generative Semantic Workspaces (GSW) -- an entity- and event-aware network of question-answer (QA) pairs, sufficient for an LLM to reconstruct the experienced situations and mine latent knowledge via reasoning-grounded inference chains on the network. Given a query, Panini only traverses the continually-updated GSW (not the verbatim documents or chunks), and retrieves the most likely inference chains. Across six QA benchmarks, Panini achieves the highest average performance, 5%-7% higher than other competitive baselines, while using 2-30x fewer answer-context tokens, supports fully open-source pipelines, and reduces unsupported answers on curated unanswerable queries. The results show that efficient and accurate structuring of experiences at write time -- as achieved by the GSW framework -- yields both efficiency and reliability gains at read time. Code is available at https://github.com/roychowdhuryresearch/gsw-memory.

cs.AI↗

Self-Supervised Distillation of Legacy Rule-Based Methods for Enhanced EEG-Based Decision-Making

High-frequency oscillations (HFOs) in intracranial Electroencephalography (iEEG) are critical biomarkers for localizing the epileptogenic zone in epilepsy treatment. However, traditional rule-based detectors for HFOs suffer from unsatisfactory precision, producing false positives that require time-consuming manual review. Supervised machine learning approaches have been used to classify the detection results, yet they typically depend on labeled datasets, which are difficult to acquire due to the need for specialized expertise. Moreover, accurate labeling of HFOs is challenging due to low inter-rater reliability and inconsistent annotation practices across institutions. The lack of a clear consensus on what constitutes a pathological HFO further challenges supervised refinement approaches. To address this, we leverage the insight that legacy detectors reliably capture clinically relevant signals despite their relatively high false positive rates. We thus propose the Self-Supervised to Label Discovery (SS2LD) framework to refine the large set of candidate events generated by legacy detectors into a precise set of pathological HFOs. SS2LD employs a variational autoencoder (VAE) for morphological pre-training to learn meaningful latent representation of the detected events. These representations are clustered to derive weak supervision for pathological events. A classifier then uses this supervision to refine detection boundaries, trained on real and VAE-augmented data. Evaluated on large multi-institutional interictal iEEG datasets, SS2LD outperforms state-of-the-art methods. SS2LD offers a scalable, label-efficient, and clinically effective strategy to identify pathological HFOs using legacy detectors.

cs.CE↗

Learning from Active Human Involvement through Proxy Value Propagation

Learning from active human involvement enables the human subject to actively intervene and demonstrate to the AI agent during training. The interaction and corrective feedback from human brings safety and AI alignment to the learning process. In this work, we propose a new reward-free active human involvement method called Proxy Value Propagation for policy optimization. Our key insight is that a proxy value function can be designed to express human intents, wherein state-action pairs in the human demonstration are labeled with high values, while those agents' actions that are intervened receive low values. Through the TD-learning framework, labeled values of demonstrated state-action pairs are further propagated to other unlabeled data generated from agents' exploration. The proxy value function thus induces a policy that faithfully emulates human behaviors. Human-in-the-loop experiments show the generality and efficiency of our method. With minimal modification to existing reinforcement learning algorithms, our method can learn to solve continuous and discrete control tasks with various human control devices, including the challenging task of driving in Grand Theft Auto V. Demo video and code are available at: https://metadriverse.github.io/pvp

cs.AI↗

Embodied Scene Understanding for Vision Language Models via MetaVQA

Vision Language Models (VLMs) demonstrate significant potential as embodied AI agents for various mobility applications. However, a standardized, closed-loop benchmark for evaluating their spatial reasoning and sequential decision-making capabilities is lacking. To address this, we present MetaVQA: a comprehensive benchmark designed to assess and enhance VLMs' understanding of spatial relationships and scene dynamics through Visual Question Answering (VQA) and closed-loop simulations. MetaVQA leverages Set-of-Mark prompting and top-down view ground-truth annotations from nuScenes and Waymo datasets to automatically generate extensive question-answer pairs based on diverse real-world traffic scenarios, ensuring object-centric and context-rich instructions. Our experiments show that fine-tuning VLMs with the MetaVQA dataset significantly improves their spatial reasoning and embodied scene comprehension in safety-critical simulations, evident not only in improved VQA accuracies but also in emerging safety-aware driving maneuvers. In addition, the learning demonstrates strong transferability from simulation to real-world observation. Code and data will be publicly available at https://metadriverse.github.io/metavqa .

cs.CV↗

MetaUrban: An Embodied AI Simulation Platform for Urban Micromobility

Public urban spaces like streetscapes and plazas serve residents and accommodate social life in all its vibrant variations. Recent advances in Robotics and Embodied AI make public urban spaces no longer exclusive to humans. Food delivery bots and electric wheelchairs have started sharing sidewalks with pedestrians, while robot dogs and humanoids have recently emerged in the street. Micromobility enabled by AI for short-distance travel in public urban spaces plays a crucial component in the future transportation system. Ensuring the generalizability and safety of AI models maneuvering mobile machines is essential. In this work, we present MetaUrban, a compositional simulation platform for the AI-driven urban micromobility research. MetaUrban can construct an infinite number of interactive urban scenes from compositional elements, covering a vast array of ground plans, object placements, pedestrians, vulnerable road users, and other mobile agents' appearances and dynamics. We design point navigation and social navigation tasks as the pilot study using MetaUrban for urban micromobility research and establish various baselines of Reinforcement Learning and Imitation Learning. We conduct extensive evaluation across mobile machines, demonstrating that heterogeneous mechanical structures significantly influence the learning and execution of AI policies. We perform a thorough ablation study, showing that the compositional nature of the simulated environments can substantially improve the generalizability and safety of the trained mobile agents. MetaUrban will be made publicly available to provide research opportunities and foster safe and trustworthy embodied AI and micromobility in cities. The code and dataset will be publicly available.

cs.CV↗

ScenarioNet: Open-Source Platform for Large-Scale Traffic Scenario Simulation and Modeling

Large-scale driving datasets such as Waymo Open Dataset and nuScenes substantially accelerate autonomous driving research, especially for perception tasks such as 3D detection and trajectory forecasting. Since the driving logs in these datasets contain HD maps and detailed object annotations which accurately reflect the real-world complexity of traffic behaviors, we can harvest a massive number of complex traffic scenarios and recreate their digital twins in simulation. Compared to the hand-crafted scenarios often used in existing simulators, data-driven scenarios collected from the real world can facilitate many research opportunities in machine learning and autonomous driving. In this work, we present ScenarioNet, an open-source platform for large-scale traffic scenario modeling and simulation. ScenarioNet defines a unified scenario description format and collects a large-scale repository of real-world traffic scenarios from the heterogeneous data in various driving datasets including Waymo, nuScenes, Lyft L5, and nuPlan datasets. These scenarios can be further replayed and interacted with in multiple views from Bird-Eye-View layout to realistic 3D rendering in MetaDrive simulator. This provides a benchmark for evaluating the safety of autonomous driving stacks in simulation before their real-world deployment. We further demonstrate the strengths of ScenarioNet on large-scale scenario generation, imitation learning, and reinforcement learning in both single-agent and multi-agent settings. Code, demo videos, and website are available at https://metadriverse.github.io/scenarionet.

cs.RO↗