arXiv subjects

Cheng Jiang

Publications and source records attributed to Cheng Jiang.

At least 37 records · Page 2Linked to original sources

arXiv2025

Intelligent Histology for Tumor Neurosurgery

The importance of rapid and accurate histologic analysis of surgical tissue in the operating room has been recognized for over a century. Our standard-of-care intraoperative pathology workflow is based on light microscopy and H\&E histology, which is slow, resource-intensive, and lacks real-time digital imaging capabilities. Here, we present an emerging and innovative method for intraoperative histologic analysis, called Intelligent Histology, that integrates artificial intelligence (AI) with stimulated Raman histology (SRH). SRH is a rapid, label-free, digital imaging method for real-time microscopic tumor tissue analysis. SRH generates high-resolution digital images of surgical specimens within seconds, enabling AI-driven tumor histologic analysis, molecular classification, and tumor infiltration detection. We review the scientific background, clinical translation, and future applications of intelligent histology in tumor neurosurgery. We focus on the major scientific and clinical studies that have demonstrated the transformative potential of intelligent histology across multiple neurosurgical specialties, including neurosurgical oncology, skull base, spine oncology, pediatric tumors, and periperal nerve tumors. Future directions include the development of AI foundation models through multi-institutional datasets, incorporating clinical and radiologic data for multimodal learning, and predicting patient outcomes. Intelligent histology represents a transformative intraoperative workflow that can reinvent real-time tumor analysis for 21st century neurosurgery.

cs.CV↗

arXiv2025

mmMirror: Device Free mmWave Indoor NLoS Localization Using Van-Atta-Array IRS

Industry 4.0 is transforming manufacturing and logistics by integrating robots into shared human environments, such as factories, warehouses, and healthcare facilities. However, the risk of human-robot collisions, especially in Non-Line-of-Sight (NLoS) scenarios like around corners, remains a critical challenge. Existing solutions, such as vision-based and LiDAR systems, often fail under occlusion, lighting constraints, or privacy concerns, while RF-based systems are limited by range and accuracy. To address these limitations, we propose mmMirror, a novel system leveraging a Van Atta Array-based millimeter-wave (mmWave) reconfigurable intelligent reflecting surface (IRS) for precise, device-free NLoS localization. mmMirror integrates seamlessly with existing frequency-modulated continuous-wave (FMCW) radars and offers: (i) robust NLoS localization with centimeter-level accuracy at ranges up to 3 m, (ii) seamless uplink and downlink communication between radar and IRS, (iii) support for multi-radar and multi-target scenarios via dynamic beam steering, and (iv) reduced scanning latency through adaptive time slot allocation. Implemented using commodity 24 GHz radars and a PCB-based IRS prototype, mmMirror demonstrates its potential in enabling safe human-robot interactions in dynamic and complex environments.

cs.NI↗

arXiv2025

Solar-CSK: Decoding Color Coded Visible Light Communications using Solar Cells

Visible Light Communication (VLC) provides an energy-efficient wireless solution by using existing LED-based illumination for high-speed data transmissions. Although solar cells offer the advantage of simultaneous energy harvesting and data reception, their broadband nature hinders accurate decoding of color-coded signals like Color Shift Keying (CSK). In this paper, we propose a novel approach exploiting the concept of tandem solar cells, multi-layer devices with partial wavelength selectivity, to capture coarse color information without resorting to energy-limiting color filters. To address the residual spectral overlap, we develop a bidirectional LSTM-based machine learning framework that infers channel characteristics by comparing solar cells' photovoltaic signals with pilot-based anchor data. Our commercial off-the-shelf (COTS) solar prototype achieves robust performance across varying distances and ambient lighting levels, significantly reducing bit error rates compared to conventional channel estimation methods. These findings mark a step toward sustainable, high-performance VLC systems powered by the multi-layer solar technologies.

cs.NI↗

arXiv2025

Choose Your Diffusion: Efficient and flexible ways to accelerate the diffusion model in fast high energy physics simulation

The diffusion model has demonstrated promising results in image generation, recently becoming mainstream and representing a notable advancement for many generative modeling tasks. Prior applications of the diffusion model for both fast event and detector simulation in high energy physics have shown exceptional performance, providing a viable solution to generate sufficient statistics within a constrained computational budget in preparation for the High Luminosity LHC. However, many of these applications suffer from slow generation with large sampling steps and face challenges in finding the optimal balance between sample quality and speed. The study focuses on the latest benchmark developments in efficient ODE/SDE-based samplers, schedulers, and fast convergence training techniques. We test on the public CaloChallenge and JetNet datasets with the designs implemented on the existing architecture, the performance of the generated classes surpass previous models, achieving significant speedup via various evaluation metrics.

physics.ins-det↗

arXiv2025

A Review of Brain-Computer Interface Technologies: Signal Acquisition Methods and Interaction Paradigms

Brain-Computer Interface (BCI) technology facilitates direct communication between the human brain and external devices, representing a substantial advancement in human-machine interaction. This review provides an in-depth analysis of various BCI paradigms, including classic paradigms, current classifications, and hybrid paradigms, each with distinct characteristics and applications. Additionally, we explore a range of signal acquisition methods, classified into non-implantation, intervention, and implantation techniques, elaborating on their principles and recent advancements. By examining the interdependence between paradigms and signal acquisition technologies, this review offers a comprehensive perspective on how innovations in one domain propel progress in the other. The goal is to present insights into the future development of more efficient, user-friendly, and versatile BCI systems, emphasizing the synergy between paradigm design and signal acquisition techniques and their potential to transform the field.

cs.HC↗

arXiv2025

A Learnable Multi-views Contrastive Framework with Reconstruction Discrepancy for Medical Time-Series

In medical time series disease diagnosis, two key challenges are identified.First, the high annotation cost of medical data leads to overfitting in models trained on label-limited, single-center datasets. To address this, we propose incorporating external data from related tasks and leveraging AE-GAN to extract prior knowledge,providing valuable references for downstream tasks. Second, many existing studies employ contrastive learning to derive more generalized medical sequence representations for diagnostic tasks, usually relying on manually designed diverse positive and negative sample pairs.However, these approaches are complex, lack generalizability, and fail to adaptively capture disease-specific features across different conditions.To overcome this, we introduce LMCF (Learnable Multi-views Contrastive Framework), a framework that integrates a multi-head attention mechanism and adaptively learns representations from different views through inter-view and intra-view contrastive learning strategies.Additionally, the pre-trained AE-GAN is used to reconstruct discrepancies in the target data as disease probabilities, which are then integrated into the contrastive learning process.Experiments on three target datasets demonstrate that our method consistently outperforms seven other baselines, highlighting its significant impact on healthcare applications such as the diagnosis of myocardial infarction, Alzheimer's disease, and Parkinson's disease.

cs.LG↗

arXiv2025

Application of Structured State Space Models to High energy physics with locality-sensitive hashing

Modern high-energy physics (HEP) experiments are increasingly challenged by the vast size and complexity of their datasets, particularly regarding large-scale point cloud processing and long sequences. In this study, to address these challenges, we explore the application of structured state space models (SSMs), proposing one of the first trials to integrate local-sensitive hashing into either a hybrid or pure Mamba Model. Our results demonstrate that pure SSMs could serve as powerful backbones for HEP problems involving tasks for long sequence data with local inductive bias. By integrating locality-sensitive hashing into Mamba blocks, we achieve significant improvements over traditional backbones in key HEP tasks, surpassing them in inference speed and physics metrics while reducing computational overhead. In key tests, our approach demonstrated promising results, presenting a viable alternative to traditional transformer backbones by significantly reducing FLOPS while maintaining robust performance.

cs.LG↗

arXiv2024

Step-Calibrated Diffusion for Biomedical Optical Image Restoration

High-quality, high-resolution medical imaging is essential for clinical care. Raman-based biomedical optical imaging uses non-ionizing infrared radiation to evaluate human tissues in real time and is used for early cancer detection, brain tumor diagnosis, and intraoperative tissue analysis. Unfortunately, optical imaging is vulnerable to image degradation due to laser scattering and absorption, which can result in diagnostic errors and misguided treatment. Restoration of optical images is a challenging computer vision task because the sources of image degradation are multi-factorial, stochastic, and tissue-dependent, preventing a straightforward method to obtain paired low-quality/high-quality data. Here, we present Restorative Step-Calibrated Diffusion (RSCD), an unpaired diffusion-based image restoration method that uses a step calibrator model to dynamically determine the number of steps required to complete the reverse diffusion process for image restoration. RSCD outperforms other widely used unpaired image restoration methods on both image quality and perceptual evaluation metrics for restoring optical images. Medical imaging experts consistently prefer images restored using RSCD in blinded comparison experiments and report minimal to no hallucinations. Finally, we show that RSCD improves performance on downstream clinical imaging tasks, including automated brain tumor diagnosis and deep tissue imaging. Our code is available at https://github.com/MLNeurosurg/restorative_step-calibrated_diffusion.

eess.IV↗

arXiv2024

Robust Load Prediction of Power Network Clusters Based on Cloud-Model-Improved Transformer

Load data from power network clusters indicates economic development in each area, crucial for predicting regional trends and guiding power enterprise decisions. The Transformer model, a leading method for load prediction, faces challenges modeling historical data due to variables like weather, events, festivals, and data volatility. To tackle this, the cloud model's fuzzy feature is utilized to manage uncertainties effectively. Presenting an innovative approach, the Cloud Model Improved Transformer (CMIT) method integrates the Transformer model with the cloud model utilizing the particle swarm optimization algorithm, with the aim of achieving robust and precise power load predictions. Through comparative experiments conducted on 31 real datasets within a power network cluster, it is demonstrated that CMIT significantly surpasses the Transformer model in terms of prediction accuracy, thereby highlighting its effectiveness in enhancing forecasting capabilities within the power network cluster sector.

cs.LG↗

arXiv2024

A self-supervised framework for learning whole slide representations

Whole slide imaging is fundamental to biomedical microscopy and computational pathology. Previously, learning representations for gigapixel-sized whole slide images (WSIs) has relied on multiple instance learning with weak labels, which do not annotate the diverse morphologic features and spatial heterogeneity of WSIs. A high-quality self-supervised learning method for WSIs would provide transferable visual representations for downstream computational pathology tasks, without the need for dense annotations. We present Slide Pre-trained Transformers (SPT) for gigapixel-scale self-supervision of WSIs. Treating WSI patches as tokens, SPT combines data transformation strategies from language and vision modeling into a general and unified framework to generate views of WSIs for self-supervised pretraining. SPT leverages the inherent regional heterogeneity, histologic feature variability, and information redundancy within WSIs to learn high-quality whole slide representations. We benchmark SPT visual representations on five diagnostic tasks across three biomedical microscopy datasets. SPT significantly outperforms baselines for histopathologic diagnosis, cancer subtyping, and genetic mutation prediction. Finally, we demonstrate that SPT consistently improves whole slide representations when using off-the-shelf, in-domain, and foundational patch encoders for whole slide multiple instance learning.

cs.CV↗

arXiv2024

BUFF: Boosted Decision Tree based Ultra-Fast Flow matching

Tabular data stands out as one of the most frequently encountered types in high energy physics. Unlike commonly homogeneous data such as pixelated images, simulating high-dimensional tabular data and accurately capturing their correlations are often quite challenging, even with the most advanced architectures. Based on the findings that tree-based models surpass the performance of deep learning models for tasks specific to tabular data, we adopt the very recent generative modeling class named conditional flow matching and employ different techniques to integrate the usage of Gradient Boosted Trees. The performances are evaluated for various tasks on different analysis level with several public datasets. We demonstrate the training and inference time of most high-level simulation tasks can achieve speedup by orders of magnitude. The application can be extended to low-level feature simulation and conditioned generations with competitive performance.

physics.ins-det↗

arXiv2024

Super-resolution of biomedical volumes with 2D supervision

Volumetric biomedical microscopy has the potential to increase the diagnostic information extracted from clinical tissue specimens and improve the diagnostic accuracy of both human pathologists and computational pathology models. Unfortunately, barriers to integrating 3-dimensional (3D) volumetric microscopy into clinical medicine include long imaging times, poor depth / z-axis resolution, and an insufficient amount of high-quality volumetric data. Leveraging the abundance of high-resolution 2D microscopy data, we introduce masked slice diffusion for super-resolution (MSDSR), which exploits the inherent equivalence in the data-generating distribution across all spatial dimensions of biological specimens. This intrinsic characteristic allows for super-resolution models trained on high-resolution images from one plane (e.g., XY) to effectively generalize to others (XZ, YZ), overcoming the traditional dependency on orientation. We focus on the application of MSDSR to stimulated Raman histology (SRH), an optical imaging modality for biological specimen analysis and intraoperative diagnosis, characterized by its rapid acquisition of high-resolution 2D images but slow and costly optical z-sectioning. To evaluate MSDSR's efficacy, we introduce a new performance metric, SliceFID, and demonstrate MSDSR's superior performance over baseline models through extensive evaluations. Our findings reveal that MSDSR not only significantly enhances the quality and resolution of 3D volumetric data, but also addresses major obstacles hindering the broader application of 3D volumetric microscopy in clinical diagnostics and biomedical research.

eess.IV↗

arXiv2024

Cross-Resolution Land Cover Classification Using Outdated Products and Transformers

Large-scale high-resolution land cover classification is a prerequisite for constructing Earth system models and addressing ecological and resource issues. Advancements in satellite sensor technology have led to an improvement in spatial resolution and wider coverage areas. Nevertheless, the lack of high-resolution labeled data is still a challenge, hindering the largescale application of land cover classification methods. In this paper, we propose a Transformerbased weakly supervised method for cross-resolution land cover classification using outdated data. First, to capture long-range dependencies without missing the fine-grained details of objects, we propose a U-Net-like Transformer based on a reverse difference mechanism (RDM) using dynamic sparse attention. Second, we propose an anti-noise loss calculation (ANLC) module based on optimal transport (OT). Anti-noise loss calculation identifies confident areas (CA) and vague areas (VA) based on the OT matrix, which relieves the impact of noises in outdated land cover products. By introducing a weakly supervised loss with weights and employing unsupervised loss, the RDM-based U-Net-like Transformer was trained. Remote sensing images with 1 m resolution and the corresponding ground-truths of six states in the United States were employed to validate the performance of the proposed method. The experiments utilized outdated land cover products with 30 m resolution from 2013 as training labels, and produced land cover maps with 1 m resolution from 2017. The results show the superiority of the proposed method compared to state-of-the-art methods. The code is available at https://github.com/yu-ni1989/ANLC-Former.

cs.CV↗

arXiv2024

Development and validation of an artificial intelligence model to accurately predict spinopelvic parameters

Objective. Achieving appropriate spinopelvic alignment has been shown to be associated with improved clinical symptoms. However, measurement of spinopelvic radiographic parameters is time-intensive and interobserver reliability is a concern. Automated measurement tools have the promise of rapid and consistent measurements, but existing tools are still limited by some degree of manual user-entry requirements. This study presents a novel artificial intelligence (AI) tool called SpinePose that automatically predicts spinopelvic parameters with high accuracy without the need for manual entry. Methods. SpinePose was trained and validated on 761 sagittal whole-spine X-rays to predict sagittal vertical axis (SVA), pelvic tilt (PT), pelvic incidence (PI), sacral slope (SS), lumbar lordosis (LL), T1-pelvic angle (T1PA), and L1-pelvic angle (L1PA). A separate test set of 40 X-rays was labeled by 4 reviewers, including fellowship-trained spine surgeons and a fellowship-trained radiologist with neuroradiology subspecialty certification. Median errors relative to the most senior reviewer were calculated to determine model accuracy on test images. Intraclass correlation coefficients (ICC) were used to assess inter-rater reliability. Results. SpinePose exhibited the following median (interquartile range) parameter errors: SVA: 2.2(2.3)mm, p=0.93; PT: 1.3(1.2)°, p=0.48; SS: 1.7(2.2)°, p=0.64; PI: 2.2(2.1)°, p=0.24; LL: 2.6(4.0)°, p=0.89; T1PA: 1.1(0.9)°, p=0.42; and L1PA: 1.4(1.6)°, p=0.49. Model predictions also exhibited excellent reliability at all parameters (ICC: 0.91-1.0). Conclusions. SpinePose accurately predicted spinopelvic parameters with excellent reliability comparable to fellowship-trained spine surgeons and neuroradiologists. Utilization of predictive AI tools in spinal imaging can substantially aid in patient selection and surgical planning.

cs.CV↗

arXiv2023

Artificial-intelligence-based molecular classification of diffuse gliomas using rapid, label-free optical imaging

Molecular classification has transformed the management of brain tumors by enabling more accurate prognostication and personalized treatment. However, timely molecular diagnostic testing for patients with brain tumors is limited, complicating surgical and adjuvant treatment and obstructing clinical trial enrollment. In this study, we developed DeepGlioma, a rapid ($< 90$ seconds), artificial-intelligence-based diagnostic screening system to streamline the molecular diagnosis of diffuse gliomas. DeepGlioma is trained using a multimodal dataset that includes stimulated Raman histology (SRH); a rapid, label-free, non-consumptive, optical imaging method; and large-scale, public genomic data. In a prospective, multicenter, international testing cohort of patients with diffuse glioma ($n=153$) who underwent real-time SRH imaging, we demonstrate that DeepGlioma can predict the molecular alterations used by the World Health Organization to define the adult-type diffuse glioma taxonomy (IDH mutation, 1p19q co-deletion and ATRX mutation), achieving a mean molecular classification accuracy of $93.3\pm 1.6\%$. Our results represent how artificial intelligence and optical histology can be used to provide a rapid and scalable adjunct to wet lab methods for the molecular screening of patients with diffuse glioma.

cs.CV↗

arXiv2023

Hierarchical discriminative learning improves visual representations of biomedical microscopy

Learning high-quality, self-supervised, visual representations is essential to advance the role of computer vision in biomedical microscopy and clinical medicine. Previous work has focused on self-supervised representation learning (SSL) methods developed for instance discrimination and applied them directly to image patches, or fields-of-view, sampled from gigapixel whole-slide images (WSIs) used for cancer diagnosis. However, this strategy is limited because it (1) assumes patches from the same patient are independent, (2) neglects the patient-slide-patch hierarchy of clinical biomedical microscopy, and (3) requires strong data augmentations that can degrade downstream performance. Importantly, sampled patches from WSIs of a patient's tumor are a diverse set of image examples that capture the same underlying cancer diagnosis. This motivated HiDisc, a data-driven method that leverages the inherent patient-slide-patch hierarchy of clinical biomedical microscopy to define a hierarchical discriminative learning task that implicitly learns features of the underlying diagnosis. HiDisc uses a self-supervised contrastive learning framework in which positive patch pairs are defined based on a common ancestry in the data hierarchy, and a unified patch, slide, and patient discriminative learning objective is used for visual SSL. We benchmark HiDisc visual representations on two vision tasks using two biomedical microscopy datasets, and demonstrate that (1) HiDisc pretraining outperforms current state-of-the-art self-supervised pretraining methods for cancer diagnosis and genetic mutation prediction, and (2) HiDisc learns high-quality visual representations using natural patch diversity without strong data augmentations.

cs.CV↗

arXiv2023

MixFormer: End-to-End Tracking with Iterative Mixed Attention

Visual object tracking often employs a multi-stage pipeline of feature extraction, target information integration, and bounding box estimation. To simplify this pipeline and unify the process of feature extraction and target information integration, in this paper, we present a compact tracking framework, termed as MixFormer, built upon transformers. Our core design is to utilize the flexibility of attention operations, and propose a Mixed Attention Module (MAM) for simultaneous feature extraction and target information integration. This synchronous modeling scheme allows to extract target-specific discriminative features and perform extensive communication between target and search area. Based on MAM, we build our MixFormer trackers simply by stacking multiple MAMs and placing a localization head on top. Specifically, we instantiate two types of MixFormer trackers, a hierarchical tracker MixCvT, and a non-hierarchical tracker MixViT. For these two trackers, we investigate a series of pre-training methods and uncover the different behaviors between supervised pre-training and self-supervised pre-training in our MixFormer trackers. We also extend the masked pre-training to our MixFormer trackers and design the competitive TrackMAE pre-training technique. Finally, to handle multiple target templates during online tracking, we devise an asymmetric attention scheme in MAM to reduce computational cost, and propose an effective score prediction module to select high-quality templates. Our MixFormer trackers set a new state-of-the-art performance on seven tracking benchmarks, including LaSOT, TrackingNet, VOT2020, GOT-10k, OTB100 and UAV123. In particular, our MixViT-L achieves AUC score of 73.3% on LaSOT, 86.1% on TrackingNet, EAO of 0.584 on VOT2020, and AO of 75.7% on GOT-10k. Code and trained models are publicly available at https://github.com/MCG-NJU/MixFormer.

cs.CV↗

arXiv2023

A Novel Efficient Signcryption Scheme for Resource-Constrained Smart Terminals in Cyber-Physical Power Systems

Most of the existing signcryption schemes generate pseudonym by key generation center (KGC) and usually choose bilinear pairing to construct authentication schemes. The drawback is that these schemes not only consume heavy computation and communication costs during information exchange, but also can not eliminate security risks due to not updating pseudonym, which do not work well for resource-constrained smart terminals in cyber-physical power systems (CPPSs). The main objective of this paper is to propose a novel efficient signcryption scheme for resource-constrained smart terminals. First, a dynamical pseudonym self-generation mechanism (DPSGM) is explored to achieve privacy preservation and avoid the source being linked. Second, combined with DPSGM, an efficient signcryption scheme based on certificateless cryptography (CLC) and elliptic curve cryptography (ECC) is designed, which reduces importantly computation and communication burden. Furthermore, under random oracle model (ROM), the confidentiality and non-repudiation of the proposed signcryption scheme are transformed into elliptic curve discrete logarithm and computational Diffie-Hellman problems that cannot be solved in polynomial time, which guarantees the security. Finally, the effectiveness and feasibility of the proposed signcryption scheme are confirmed by experimental analyses.

cs.CR↗