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Chenwei Zhang

Publications and source records attributed to Chenwei Zhang.

At least 19 recordsLinked to original sources

TaoMate: Anchor-Guided Memory Bridging Evolving and Reference States for Real-Time Audio-Video Digital Human Generation

Real-time long-form digital-human generation relies on causal models to extend audio-visual content while preserving subject appearance and audio-video synchronization across successive segments. A bounded cache retains local motion and phonetic context but discards older evidence, whereas attending to the complete generated history is computationally expensive and can propagate accumulated errors. We present \method, an anchor-guided persistent-memory framework for few-step joint audio-video generation. The framework preserves an immutable visual anchor, compresses completed video and audio blocks into fixed-capacity dynamic states, and retrieves those states through modality-specific residual attention without extending the active cache. A reference-aware modulation method additionally conditions video features on dynamic and anchor appearance statistics. Anchor-preserving causal-context distillation varies rollout horizon, prefix provenance, and cache-history reliability while keeping the immutable visual anchor unperturbed. By separating persistent memory from stage-local denoising dependencies, \method further admits stage-parallel execution across blocks, accelerating autoregressive inference without pipeline-specific retraining. We evaluate long-form video continuations with appearance, temporal, synchronization, facial, and speech diagnostics. Results show that \method preserves stable appearance across prompt-conditioned segments and strong audio-visual synchronization under autoregressive generation. Our project page is https://taoliveaigc.github.io/TaoMate.

cs.CV

Unintended Negative Impacts of Promotional Language in Patent Evaluation

Promotional language has been increasingly used to aid the communication of innovative ideas in science. Yet, less is known about its role in the context of technological innovation. Here, we use a validated and domain-diagnosed lexicon of 135 promotional words to study the association between promotional language and patent evaluation outcomes among 2.7 million USPTO patent applications. Our large-scale study reveals three unexpected findings. First, in contrast to scientific evaluation, we find that a higher frequency of promotional words is negatively associated with the probability of an application being (i) granted a patent, (ii) transferred ownership, and (iii) successfully appealed. This promotional penalty holds even after accounting for a range of confounding factors and is largely robust across different technological areas. Among matched samples, the difference in the success rate between the lowest and highest promotional density quintile is 5.5, 5.9, and 5.3 percentage points for patentability, transferability, and rejection reversal. Second, contrary to institutional skepticism, we show that promotional language is not a mask of weak technology, but objectively reflects the degree of combinatorial novelty and future citation impact. Third, digging into the mechanisms, we find that the tolerance to promotional framing is strongly moderated by human factors, with men and experienced examiners showing a higher acceptance of promotional narratives than women and novice examiners. By revealing an emerging paradox in the patent system, our study offers theoretical and practical implications for improving patent evaluation through more objective scrutiny of linguistic patterns in patent filings.

cs.CL

Enhancing Cryo-EM Density Map Segmentation in Phenix for Improved Atomic Model Building

We introduce PhenixCraft, a fully automated pipeline for building atomic models from cryo-EM density maps. By integrating AlphaFold predictions, we enhance the map-segmentation step in Phenix during model building, addressing challenges posed by noise and artifacts that traditionally hinder this step. Our results demonstrate PhenixCraft's superior performance in TM-scores and sequence accuracy, significantly improving upon the limitations and inefficiencies of traditional model building using Phenix.

q-bio.BM

T$^2$PO: Uncertainty-Guided Exploration Control for Stable Multi-Turn Agentic Reinforcement Learning

Recent progress in multi-turn reinforcement learning (RL) has significantly improved reasoning LLMs' performances on complex interactive tasks. Despite advances in stabilization techniques such as fine-grained credit assignment and trajectory filtering, instability remains pervasive and often leads to training collapse. We argue that this instability stems from inefficient exploration in multi-turn settings, where policies continue to generate low-information actions that neither reduce uncertainty nor advance task progress. To address this issue, we propose Token- and Turn-level Policy Optimization (T$^2$PO), an uncertainty-aware framework that explicitly controls exploration at fine-grained levels. At the token level, T$^2$PO monitors uncertainty dynamics and triggers a thinking intervention once the marginal uncertainty change falls below a threshold. At the turn level, T$^2$PO identifies interactions with negligible exploration progress and dynamically resamples such turns to avoid wasted rollouts. We evaluate T$^2$PO in diverse environments, including WebShop, ALFWorld, and Search QA, demonstrating substantial gains in training stability and performance improvements with better exploration efficiency. Code is available at: https://github.com/WillDreamer/T2PO.

cs.AI

Applications of deep generative models to DNA reaction kinetics and to cryogenic electron microscopy

This dissertation explores how deep generative models can advance the analysis of challenging biological problems by integrating domain knowledge with deep learning. It focuses on two areas: DNA reaction kinetics and cryogenic electron microscopy (cryo-EM). In the first part, we present ViDa, a biophysics-informed framework leveraging variational autoencoders (VAEs) and geometric scattering transforms to generate biophysically-plausible embeddings of DNA reaction kinetics simulations. These embeddings are reduced to a two-dimensional space to visualize DNA hybridization and toehold-mediated strand displacement reactions. ViDa preserves structure and clusters trajectory ensembles into reaction pathways, making simulation results more interpretable and revealing new mechanistic insights. In the second part, we address key challenges in cryo-EM density map interpretation and protein structure modeling. We provide a comprehensive review and benchmarking of deep learning methods for atomic model building, with improved evaluation metrics and practical guidance. We then present Struc2mapGAN, a generative adversarial network that synthesizes high-fidelity experimental-like cryo-EM density maps from protein structures. Finally, we present CryoSAMU, a structure-aware multimodal U-Net that enhances intermediate-resolution cryo-EM maps by integrating density features with structural embeddings from protein language models via cross-attention. Overall, these contributions demonstrate the potential of deep generative models to interpret DNA reaction mechanisms and advance cryo-EM density map analysis and protein structure modeling.

cs.LG

R3-VAE: Reference Vector-Guided Rating Residual Quantization VAE for Generative Recommendation

Generative Recommendation (GR) has gained traction for its merits of superior performance and cold-start capability. As the vital role in GR, Semantic Identifiers (SIDs) represent item semantics through discrete tokens. However, current techniques for SID generation based on vector quantization face two main challenges: (i) training instability, stemming from insufficient gradient propagation through the straight-through estimator and sensitivity to initialization; and (ii) inefficient SID quality assessment, where industrial practice still depends on costly GR training and A/B testing. To address these challenges, we propose Reference Vector-Guided Rating Residual Quantization VAE (R3-VAE). This framework incorporates three key innovations: (i) a reference vector that functions as a semantic anchor for the initial features, thereby mitigating sensitivity to initialization; (ii) a dot product-based rating mechanism designed to stabilize the training process and prevent codebook collapse; and (iii) two SID evaluation metrics, Semantic Cohesion and Preference Discrimination, serving as regularization terms during training. Empirical results on six benchmarks demonstrate that R3-VAE outperforms state-of-the-art methods, achieving an average improvement of 14.5% in Recall@10 and 15.5% in NDCG@10 across three public datasets (Beauty, Sports, and Toys). Furthermore, we perform GR training and online A/B tests on Toutiao. Our method achieves a 1.62% improvement in MRR and a 0.83% gain in StayTime/U versus baselines. Additionally, we employ R3-VAE to replace the item ID of CTR model, resulting in significant improvements in content cold start by 15.36%, corroborating the strong applicability and business value in industry-scale recommendation scenarios.

cs.IR

SynPlanResearch-R1: Encouraging Tool Exploration for Deep Research with Synthetic Plans

Research Agents enable models to gather information from the web using tools to answer user queries, requiring them to dynamically interleave internal reasoning with tool use. While such capabilities can in principle be learned via reinforcement learning with verifiable rewards (RLVR), we observe that agents often exhibit poor exploration behaviors, including premature termination and biased tool usage. As a result, RLVR alone yields limited improvements. We propose SynPlanResearch-R1, a framework that synthesizes tool-use trajectories that encourage deeper exploration to shape exploration during cold-start supervised fine-tuning, providing a strong initialization for subsequent RL. Across seven multi-hop and open-web benchmarks, \framework improves performance by up to 6.0% on Qwen3-8B and 5.8% on Qwen3-4B backbones respectively compared to SOTA baselines. Further analyses of tool-use patterns and training dynamics compared to baselines shed light on the factors underlying these gains. Our code is publicly available at https://github.com/HansiZeng/syn-plan-research.

cs.AI

Not All Candidates are Created Equal: A Heterogeneity-Aware Approach to Pre-ranking in Recommender Systems

Most large-scale recommender systems follow a multi-stage cascade of retrieval, pre-ranking, ranking, and re-ranking. A key challenge at the pre-ranking stage arises from the heterogeneity of training instances sampled from coarse-grained retrieval results, fine-grained ranking signals, and exposure feedback. Our analysis reveals that prevailing pre-ranking methods, which indiscriminately mix heterogeneous samples, suffer from gradient conflicts: hard samples dominate training while easy ones remain underutilized, leading to suboptimal performance. We further show that the common practice of uniformly scaling model complexity across all samples is inefficient, as it overspends computation on easy cases and slows training without proportional gains. To address these limitations, this paper presents Heterogeneity-Aware Adaptive Pre-ranking (HAP), a unified framework that mitigates gradient conflicts through conflict-sensitive sampling coupled with tailored loss design, while adaptively allocating computational budgets across candidates. Specifically, HAP disentangles easy and hard samples, directing each subset along dedicated optimization paths. Building on this separation, it first applies lightweight models to all candidates for efficient coverage, and further engages stronger models on the hard ones, maintaining accuracy while reducing cost. This approach not only improves pre-ranking effectiveness but also provides a practical perspective on scaling strategies in industrial recommender systems. HAP has been deployed in the Toutiao production system for 9 months, yielding up to 0.4% improvement in user app usage duration and 0.05% in active days, without additional computational cost. We also release a large-scale industrial hybrid-sample dataset to enable the systematic study of source-driven candidate heterogeneity in pre-ranking.

cs.IR

From Web Search towards Agentic Deep Research: Incentivizing Search with Reasoning Agents

Information retrieval is a cornerstone of modern knowledge acquisition, enabling billions of queries each day across diverse domains. However, traditional keyword-based search engines are increasingly inadequate for handling complex, multi-step information needs. Our position is that Large Language Models (LLMs), endowed with reasoning and agentic capabilities, are ushering in a new paradigm termed Agentic Deep Research. These systems transcend conventional information search techniques by tightly integrating autonomous reasoning, iterative retrieval, and information synthesis into a dynamic feedback loop. We trace the evolution from static web search to interactive, agent-based systems that plan, explore, and learn. We also introduce a test-time scaling law to formalize the impact of computational depth on reasoning and search. Supported by benchmark results and the rise of open-source implementations, we demonstrate that Agentic Deep Research not only significantly outperforms existing approaches, but is also poised to become the dominant paradigm for future information seeking. All the related resources, including industry products, research papers, benchmark datasets, and open-source implementations, are collected for the community in https://github.com/DavidZWZ/Awesome-Deep-Research.

cs.IR

PersonaAgent: Bridging Memory and Action for Personalized LLM Agents

Large Language Model (LLM) empowered agents have recently emerged as advanced paradigms that exhibit impressive capabilities in a wide range of domains and tasks. Despite their potential, current LLM agents often adopt a one-size-fits-all approach, lacking the flexibility to respond to users' varying needs and preferences. This limitation motivates us to develop PersonaAgent, the first personalized LLM agent framework designed to address versatile personalization tasks. Specifically, PersonaAgent integrates two complementary components - a personalized memory module that includes episodic and semantic memory mechanisms; a personalized action module that enables the agent to perform tool actions tailored to the user. At the core, the persona (defined as unique system prompt for each user) functions as an intermediary: it leverages insights from personalized memory to control agent actions, while the outcomes of these actions in turn refine the memory. Based on the framework, we propose a test-time user-preference alignment strategy that simulate the latest n interactions to optimize the persona prompt, ensuring real-time user preference alignment through textual loss feedback between simulated and ground-truth responses. Experimental evaluations demonstrate that PersonaAgent significantly outperforms other baseline methods by not only personalizing the action space effectively but also scaling during test-time real-world applications. These results underscore the feasibility and potential of our approach in delivering tailored, dynamic user experiences.

cs.AI

CryoSAMU: Enhancing 3D Cryo-EM Density Maps of Protein Structures at Intermediate Resolution with Structure-Aware Multimodal U-Nets

Enhancing cryogenic electron microscopy (cryo-EM) 3D density maps at intermediate resolution (4-8 {\AA}) is crucial in protein structure determination. Recent advances in deep learning have led to the development of automated approaches for enhancing experimental cryo-EM density maps. Yet, these methods are not optimized for intermediate-resolution maps and rely on map density features alone. To address this, we propose CryoSAMU, a novel method designed to enhance 3D cryo-EM density maps of protein structures using structure-aware multimodal U-Nets and trained on curated intermediate-resolution density maps. We comprehensively evaluate CryoSAMU across various metrics and demonstrate its competitive performance compared to state-of-the-art methods. Notably, CryoSAMU achieves significantly faster processing speed, showing promise for future practical applications. Our code is available at https://github.com/chenwei-zhang/CryoSAMU.

cs.CV

SCKD: Semi-Supervised Cross-Modality Knowledge Distillation for 4D Radar Object Detection

3D object detection is one of the fundamental perception tasks for autonomous vehicles. Fulfilling such a task with a 4D millimeter-wave radar is very attractive since the sensor is able to acquire 3D point clouds similar to Lidar while maintaining robust measurements under adverse weather. However, due to the high sparsity and noise associated with the radar point clouds, the performance of the existing methods is still much lower than expected. In this paper, we propose a novel Semi-supervised Cross-modality Knowledge Distillation (SCKD) method for 4D radar-based 3D object detection. It characterizes the capability of learning the feature from a Lidar-radar-fused teacher network with semi-supervised distillation. We first propose an adaptive fusion module in the teacher network to boost its performance. Then, two feature distillation modules are designed to facilitate the cross-modality knowledge transfer. Finally, a semi-supervised output distillation is proposed to increase the effectiveness and flexibility of the distillation framework. With the same network structure, our radar-only student trained by SCKD boosts the mAP by 10.38% over the baseline and outperforms the state-of-the-art works on the VoD dataset. The experiment on ZJUODset also shows 5.12% mAP improvements on the moderate difficulty level over the baseline when extra unlabeled data are available. Code is available at https://github.com/Ruoyu-Xu/SCKD.

cs.CV

Shopping MMLU: A Massive Multi-Task Online Shopping Benchmark for Large Language Models

Online shopping is a complex multi-task, few-shot learning problem with a wide and evolving range of entities, relations, and tasks. However, existing models and benchmarks are commonly tailored to specific tasks, falling short of capturing the full complexity of online shopping. Large Language Models (LLMs), with their multi-task and few-shot learning abilities, have the potential to profoundly transform online shopping by alleviating task-specific engineering efforts and by providing users with interactive conversations. Despite the potential, LLMs face unique challenges in online shopping, such as domain-specific concepts, implicit knowledge, and heterogeneous user behaviors. Motivated by the potential and challenges, we propose Shopping MMLU, a diverse multi-task online shopping benchmark derived from real-world Amazon data. Shopping MMLU consists of 57 tasks covering 4 major shopping skills: concept understanding, knowledge reasoning, user behavior alignment, and multi-linguality, and can thus comprehensively evaluate the abilities of LLMs as general shop assistants. With Shopping MMLU, we benchmark over 20 existing LLMs and uncover valuable insights about practices and prospects of building versatile LLM-based shop assistants. Shopping MMLU can be publicly accessed at https://github.com/KL4805/ShoppingMMLU. In addition, with Shopping MMLU, we host a competition in KDD Cup 2024 with over 500 participating teams. The winning solutions and the associated workshop can be accessed at our website https://amazon-kddcup24.github.io/.

cs.LG

Learning to Generalize Unseen Domains via Multi-Source Meta Learning for Text Classification

With the rapid development of deep learning methods, there have been many breakthroughs in the field of text classification. Models developed for this task have been shown to achieve high accuracy. However, most of these models are trained using labeled data from seen domains. It is difficult for these models to maintain high accuracy in a new challenging unseen domain, which is directly related to the generalization of the model. In this paper, we study the multi-source Domain Generalization of text classification and propose a framework to use multiple seen domains to train a model that can achieve high accuracy in an unseen domain. Specifically, we propose a multi-source meta-learning Domain Generalization framework to simulate the process of model generalization to an unseen domain, so as to extract sufficient domain-related features. We introduced a memory mechanism to store domain-specific features, which coordinate with the meta-learning framework. Besides, we adopt the novel "jury" mechanism that enables the model to learn sufficient domain-invariant features. Experiments demonstrate that our meta-learning framework can effectively enhance the ability of the model to generalize to an unseen domain and can outperform the state-of-the-art methods on multi-source text classification datasets.

cs.LG

Struc2mapGAN: improving synthetic cryo-EM density maps with generative adversarial networks

Generating synthetic cryogenic electron microscopy 3D density maps from molecular structures has potential important applications in structural biology. Yet existing simulation-based methods cannot mimic all the complex features present in experimental maps, such as secondary structure elements. As an alternative, we propose struc2mapGAN, a novel data-driven method that employs a generative adversarial network to produce improved experimental-like density maps from molecular structures. More specifically, struc2mapGAN uses a nested U-Net architecture as the generator, with an additional L1 loss term and further processing of raw training experimental maps to enhance learning efficiency. While struc2mapGAN can promptly generate maps after training, we demonstrate that it outperforms existing simulation-based methods for a wide array of tested maps and across various evaluation metrics.

cs.LG

APTNESS: Incorporating Appraisal Theory and Emotion Support Strategies for Empathetic Response Generation

Empathetic response generation is designed to comprehend the emotions of others and select the most appropriate strategies to assist them in resolving emotional challenges. Empathy can be categorized into cognitive empathy and affective empathy. The former pertains to the ability to understand and discern the emotional issues and situations of others, while the latter involves the capacity to provide comfort. To enhance one's empathetic abilities, it is essential to develop both these aspects. Therefore, we develop an innovative framework that combines retrieval augmentation and emotional support strategy integration. Our framework starts with the introduction of a comprehensive emotional palette for empathy. We then apply appraisal theory to decompose this palette and create a database of empathetic responses. This database serves as an external resource and enhances the LLM's empathy by integrating semantic retrieval mechanisms. Moreover, our framework places a strong emphasis on the proper articulation of response strategies. By incorporating emotional support strategies, we aim to enrich the model's capabilities in both cognitive and affective empathy, leading to a more nuanced and comprehensive empathetic response. Finally, we extract datasets ED and ET from the empathetic dialogue dataset \textsc{EmpatheticDialogues} and ExTES based on dialogue length. Experiments demonstrate that our framework can enhance the empathy ability of LLMs from both cognitive and affective empathy perspectives. Our code is released at https://github.com/CAS-SIAT-XinHai/APTNESS.

cs.CL

CORI: CJKV Benchmark with Romanization Integration -- A step towards Cross-lingual Transfer Beyond Textual Scripts

Naively assuming English as a source language may hinder cross-lingual transfer for many languages by failing to consider the importance of language contact. Some languages are more well-connected than others, and target languages can benefit from transferring from closely related languages; for many languages, the set of closely related languages does not include English. In this work, we study the impact of source language for cross-lingual transfer, demonstrating the importance of selecting source languages that have high contact with the target language. We also construct a novel benchmark dataset for close contact Chinese-Japanese-Korean-Vietnamese (CJKV) languages to further encourage in-depth studies of language contact. To comprehensively capture contact between these languages, we propose to integrate Romanized transcription beyond textual scripts via Contrastive Learning objectives, leading to enhanced cross-lingual representations and effective zero-shot cross-lingual transfer.

cs.CL

Enhanced User Interaction in Operating Systems through Machine Learning Language Models

With the large language model showing human-like logical reasoning and understanding ability, whether agents based on the large language model can simulate the interaction behavior of real users, so as to build a reliable virtual recommendation A/B test scene to help the application of recommendation research is an urgent, important and economic value problem. The combination of interaction design and machine learning can provide a more efficient and personalized user experience for products and services. This personalized service can meet the specific needs of users and improve user satisfaction and loyalty. Second, the interactive system can understand the user's views and needs for the product by providing a good user interface and interactive experience, and then use machine learning algorithms to improve and optimize the product. This iterative optimization process can continuously improve the quality and performance of the product to meet the changing needs of users. At the same time, designers need to consider how these algorithms and tools can be combined with interactive systems to provide a good user experience. This paper explores the potential applications of large language models, machine learning and interaction design for user interaction in recommendation systems and operating systems. By integrating these technologies, more intelligent and personalized services can be provided to meet user needs and promote continuous improvement and optimization of products. This is of great value for both recommendation research and user experience applications.

cs.IR