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Chenyu Li

Publications and source records attributed to Chenyu Li.

At least 19 recordsLinked to original sources

AgentHOI: Multi-Agent Reasoning for Human-Object-Interaction Video Generation via Implicit Representation Alignment

Recent advances in video diffusion models have spurred interest in human-object interaction (HOI) video generation, which demands fine-grained control over interaction logic beyond single-subject animation. However, existing HOI methods rely heavily on explicit motion control, limiting scalability and generalization across diverse objects and interactions. In this study, we propose AgentHOI, a text-driven HOI video generation following a thinking-before-generation framework that bridges the gap between high-level textual intent and physical execution through multi-agent reasoning over perception, interaction, and motion planning. Building upon the generated interaction plans, we further strengthen text-driven motion understanding. We introduce an implicit text-motion alignment strategy that distills text-to-motion priors into the video diffusion model, enabling robust HOI synthesis without explicit motion inputs at inference. Experiments show that AgentHOI significantly improves interaction naturalness, object appearance preservation, and adherence to complex textual instructions across challenging object-centric scenarios such as wearing and riding. The code is available at https://github.com/bone-11/agenthoi.

cs.CV

Understanding Fortunetelling with Large Language Models in China: User Practices, Perceptions, and Impacts on Beliefs and Decisions

Fortunetelling is a cultural practice for navigating uncertainty, often associated with people's beliefs and decisions. Fortunetelling with recent large language models (LLMs) introduces new opportunities and risks. This paper conducts qualitative studies to understand users' practices, perceptions, and impacts of LLM fortunetelling in China. We first analyze 1,045 posts on Chinese social media, yielding a comprehensive taxonomy of the diverse foretold topics (e.g., career, romance), emotion reactions (e.g., surprise, worry), and perceived credibility (e.g., doubt, trust) of LLM fortunetelling. Then, we conduct interviews with 20 users of LLM fortunetelling. The findings indicate that users treat LLM fortunetelling as a tool less for accurate prediction but more for emotional support. While the fortunetelling results rarely change users' initial beliefs or decisions, they are associated with subtle mindset shifts, with some users reporting small behavioral adjustments. We discuss implications for gaining benefits from LLM fortunetelling.

cs.HC

Students using GenAI lag behind in problem-solving competence: an agent-based study of classroom networks

The development of problem-solving competence (PSC) among high school students is foundational for preparing resilient and adaptive citizens. Generative artificial intelligence (GenAI) can support this process, but it may also encourage students to offload part of the cognitive work that is necessary for deep learning. While the individual effects of GenAI use are increasingly studied, its collective consequences for competence development within classroom environments remain underexplored. In this study, we use an agent-based model to simulate the evolution of PSC in a high school physics classroom, where students complete tasks individually, in collaboration with peers, or with the support of GenAI. By comparing classrooms with and without access to GenAI across different peer-network structures, we show that GenAI use can diminish competence development and increase the share of students remaining in lower competence tiers. These results suggest that the educational impact of GenAI should be assessed not only through individual learning outcomes but also through its effects on collective competence dynamics.

physics.soc-ph

Simple Survival End Point Calculator

In the study of survival endpoints, the size of the sample is crucial. The calculation of the sample size for survival endpoints was first proposed and presented by Freedman based on the logrank statistic. Later, many statisticians gradually introduced multiple factors such as dropout rate and delayed onset, proposed various estimation methods including the lrstat method, and developed corresponding statistical programs. However, the application of professional statistical functions is relatively complex. Based on this, this paper has developed a corresponding visual web application on the basis of the R package lrstat and powerSurvEpi, and tested its functions and program accordingly. The test results are basically consistent with the case, proving the effectiveness of the application.

stat.AP

What Makes a Medical Checker Trainable? Diagnosing Signal Collapse and Reward Hacking in Checker-Guided RAG for Biomedical QA

Medical RAG needs evidence-grounded claims, so plugging a claim-level NLI checker into retrieval-augmented RL is intuitive. \textbf{We find that the checker's \emph{output distribution} during training, not its held-out accuracy, decides whether it provides trainable gradient.} We compare four NLI checker back-ends as process rewards inside a GRPO-trained medical RAG agent (Qwen2.5-7B, replicated on Qwen3-4B and Llama-3.1-8B) across four held-out medical QA benchmarks. Three diagnostic findings emerge. \textbf{(i)} Signal collapse is log-prob-specific: LLM log-probability scoring labels over 97\% of claims neutral -- collapsing the RL gradient to zero -- while a calibrated MedNLI classifier scores the same pairs non-degenerately. \textbf{(ii)} Moderate signal beats strong signal on answer quality: a strong proprietary checker triggers a three-step reward-hacking cascade -- ultra-short answers, search avoidance, language collapse -- so a moderate-signal local classifier trains a higher-quality model (\textbf{+12\% BERTScore over zero-shot, no GPT dependency}). \textbf{(iii)} Signal strength is policy-dependent: the same checker registers as moderate on one policy but strong on another without triggering the cascade end-state. We frame these as boundary conditions for verifier-as-reward systems.

cs.CL

Endogenous drivers of gender disparity in online dating

In its early days, online dating was heralded as a great equalizer, removing biases built into the structures of heterosexuality courtship. However, as repeatedly observed, that prophecy was never fulfilled, and some biases have even become exacerbated. In this paper, we identify a general endogenous mechanism that drives the widening of the gender gap in first-contact rates of heterosexual dating. This mechanism relies on assumptions about the participants' expectations of new contacts and their time constraints. We formulate this symmetry-breaking mechanism as a system of differential equations and analyze its fixed points and their stability.

physics.soc-ph

A Scoping Review of LLM-as-a-Judge in Healthcare and the MedJUDGE Framework

As large language models (LLMs) increasingly generate and process clinical text, scalable evaluation has become critical. LLM-as-a-Judge (LaaJ), which uses LLMs to evaluate model outputs, offers a scalable alternative to costly expert review, but its healthcare adoption raises safety and bias concerns. We conducted a PRISMA-ScR scoping review of six databases (January 2020-January 2026), screening 11,727 studies and including 49. The landscape was dominated by evaluation and benchmarking applications (n=37, 75.5%), pointwise scoring (n=42, 85.7%), and GPT-family judges (n=36, 73.5%). Despite growing adoption, validation rigor was limited: among 36 studies with human involvement, the median number of expert validators was 3, while 13 (26.5%) used none. Risk of bias testing was absent in 36 studies (73.5%), only 1 (2.0%) examined demographic fairness, and none assessed temporal stability or patient context. Deployment remained limited, with 1 study (2.0%) reaching production and four (8.2%) prototype stage. Importantly, these gaps may interact: when judges and evaluated systems share training data or architectures, they may inherit similar blind spots, and agreement metrics may fail to distinguish true validity from shared errors. Minimal human oversight, limited bias assessment, and model monoculture together represent a governance gap where current validation may miss clinically significant errors. To address this, we propose MedJUDGE (Medical Judge Utility, De-biasing, Governance and Evaluation), a risk-stratified three-pillar framework organized around validity, safety, and accountability across clinical risk tiers, providing deployment-oriented evaluation guidance for healthcare LaaJ systems.

cs.CY

Foundation Models in Remote Sensing: Evolving from Unimodality to Multimodality

Remote sensing (RS) techniques are increasingly crucial for deepening our understanding of the planet. As the volume and diversity of RS data continue to grow exponentially, there is an urgent need for advanced data modeling and understanding capabilities to manage and interpret these vast datasets effectively. Foundation models present significant new growth opportunities and immense potential to revolutionize the RS field. In this paper, we conduct a comprehensive technical survey on foundation models in RS, offering a brand-new perspective by exploring their evolution from unimodality to multimodality. We hope this work serves as a valuable entry point for researchers interested in both foundation models and RS and helps them launch new projects or explore new research topics in this rapidly evolving area. This survey addresses the following three key questions: What are foundation models in RS? Why are foundation models needed in RS? How can we effectively guide junior researchers in gaining a comprehensive and practical understanding of foundation models in RS applications? More specifically, we begin by outlining the background and motivation, emphasizing the importance of foundation models in RS. We then review existing foundation models in RS, systematically categorizing them into unimodal and multimodal approaches. Additionally, we provide a tutorial-like section to guide researchers, especially beginners, on how to train foundation models in RS and apply them to real-world tasks. The survey aims to equip researchers in RS with a deeper and more efficient understanding of foundation models, enabling them to get started easily and effectively apply these models across various RS applications.

cs.CV

Hyperspectral Imaging

Hyperspectral imaging (HSI) is an advanced sensing modality that simultaneously captures spatial and spectral information, enabling non-invasive, label-free analysis of material, chemical, and biological properties. This Primer presents a comprehensive overview of HSI, from the underlying physical principles and sensor architectures to key steps in data acquisition, calibration, and correction. We summarize common data structures and highlight classical and modern analysis methods, including dimensionality reduction, classification, spectral unmixing, and AI-driven techniques such as deep learning. Representative applications across Earth observation, precision agriculture, biomedicine, industrial inspection, cultural heritage, and security are also discussed, emphasizing HSI's ability to uncover sub-visual features for advanced monitoring, diagnostics, and decision-making. Persistent challenges, such as hardware trade-offs, acquisition variability, and the complexity of high-dimensional data, are examined alongside emerging solutions, including computational imaging, physics-informed modeling, cross-modal fusion, and self-supervised learning. Best practices for dataset sharing, reproducibility, and metadata documentation are further highlighted to support transparency and reuse. Looking ahead, we explore future directions toward scalable, real-time, and embedded HSI systems, driven by sensor miniaturization, self-supervised learning, and foundation models. As HSI evolves into a general-purpose, cross-disciplinary platform, it holds promise for transformative applications in science, technology, and society.

cs.CV

Scaling Medical Reasoning Verification via Tool-Integrated Reinforcement Learning

Large language models have achieved strong performance on medical reasoning benchmarks, yet their deployment in clinical settings demands rigorous verification to ensure factual accuracy. While reward models offer a scalable approach for reasoning trace verification, existing methods face two limitations: they produce only scalar reward values without explicit justification, and they rely on single-pass retrieval that precludes adaptive knowledge access as verification unfolds. We introduce $\method$, an agentic framework that addresses these limitations by training medical reasoning verifiers to iteratively query external medical corpora during evaluation. Our approach combines tool-augmented verification with an iterative reinforcement learning paradigm that requires only trace-level supervision, alongside an adaptive curriculum mechanism that dynamically adjusts training data distribution. Across four medical reasoning benchmarks, $\method$ achieves substantial gains over existing methods, improving MedQA accuracy by 23.5% and MedXpertQA by 32.0% relative to the base generator in particular. Crucially, $\method$ demonstrates an $\mathbf{8\times}$ reduction in sampling budget requirement compared to prior reward model baselines. These findings establish that grounding verification in dynamically retrieved evidence offers a principled path toward more reliable medical reasoning systems.

cs.AI

MedRAGChecker: Claim-Level Verification for Biomedical Retrieval-Augmented Generation

Biomedical retrieval-augmented generation (RAG) can ground LLM answers in medical literature, yet long-form outputs often contain isolated unsupported or contradictory claims with safety implications. We introduce MedRAGChecker, a claim-level verification and diagnostic framework for biomedical RAG. Given a question, retrieved evidence, and a generated answer, MedRAGChecker decomposes the answer into atomic claims and estimates claim support by combining evidence-grounded natural language inference (NLI) with biomedical knowledge-graph (KG) consistency signals. Aggregating claim decisions yields answer-level diagnostics that help disentangle retrieval and generation failures, including faithfulness, under-evidence, contradiction, and safety-critical error rates. To enable scalable evaluation, we distill the pipeline into compact biomedical models and use an ensemble verifier with class-specific reliability weighting. Experiments on four biomedical QA benchmarks show that MedRAGChecker reliably flags unsupported and contradicted claims and reveals distinct risk profiles across generators, particularly on safety-critical biomedical relations.

cs.CL

KANO: Kolmogorov-Arnold Neural Operator for Image Super-Resolution

The highly nonlinear degradation process, complex physical interactions, and various sources of uncertainty render single-image Super-resolution (SR) a particularly challenging task. Existing interpretable SR approaches, whether based on prior learning or deep unfolding optimization frameworks, typically rely on black-box deep networks to model latent variables, which leaves the degradation process largely unknown and uncontrollable. Inspired by the Kolmogorov-Arnold theorem (KAT), we for the first time propose a novel interpretable operator, termed Kolmogorov-Arnold Neural Operator (KANO), with the application to image SR. KANO provides a transparent and structured representation of the latent degradation fitting process. Specifically, we employ an additive structure composed of a finite number of B-spline functions to approximate continuous spectral curves in a piecewise fashion. By learning and optimizing the shape parameters of these spline functions within defined intervals, our KANO accurately captures key spectral characteristics, such as local linear trends and the peak-valley structures at nonlinear inflection points, thereby endowing SR results with physical interpretability. Furthermore, through theoretical modeling and experimental evaluations across natural images, aerial photographs, and satellite remote sensing data, we systematically compare multilayer perceptrons (MLPs) and Kolmogorov-Arnold networks (KANs) in handling complex sequence fitting tasks. This comparative study elucidates the respective advantages and limitations of these models in characterizing intricate degradation mechanisms, offering valuable insights for the development of interpretable SR techniques.

cs.CV

Any-Optical-Model: A Universal Foundation Model for Optical Remote Sensing

Optical satellites, with their diverse band layouts and ground sampling distances, supply indispensable evidence for tasks ranging from ecosystem surveillance to emergency response. However, significant discrepancies in band composition and spatial resolution across different optical sensors present major challenges for existing Remote Sensing Foundation Models (RSFMs). These models are typically pretrained on fixed band configurations and resolutions, making them vulnerable to real world scenarios involving missing bands, cross sensor fusion, and unseen spatial scales, thereby limiting their generalization and practical deployment. To address these limitations, we propose Any Optical Model (AOM), a universal RSFM explicitly designed to accommodate arbitrary band compositions, sensor types, and resolution scales. To preserve distinctive spectral characteristics even when bands are missing or newly introduced, AOM introduces a spectrum-independent tokenizer that assigns each channel a dedicated band embedding, enabling explicit encoding of spectral identity. To effectively capture texture and contextual patterns from sub-meter to hundred-meter imagery, we design a multi-scale adaptive patch embedding mechanism that dynamically modulates the receptive field. Furthermore, to maintain global semantic consistency across varying resolutions, AOM incorporates a multi-scale semantic alignment mechanism alongside a channel-wise self-supervised masking and reconstruction pretraining strategy that jointly models spectral-spatial relationships. Extensive experiments on over 10 public datasets, including those from Sentinel-2, Landsat, and HLS, demonstrate that AOM consistently achieves state-of-the-art (SOTA) performance under challenging conditions such as band missing, cross sensor, and cross resolution settings.

cs.CV

MambaX: Image Super-Resolution with State Predictive Control

Image super-resolution (SR) is a critical technology for overcoming the inherent hardware limitations of sensors. However, existing approaches mainly focus on directly enhancing the final resolution, often neglecting effective control over error propagation and accumulation during intermediate stages. Recently, Mamba has emerged as a promising approach that can represent the entire reconstruction process as a state sequence with multiple nodes, allowing for intermediate intervention. Nonetheless, its fixed linear mapper is limited by a narrow receptive field and restricted flexibility, which hampers its effectiveness in fine-grained images. To address this, we created a nonlinear state predictive control model \textbf{MambaX} that maps consecutive spectral bands into a latent state space and generalizes the SR task by dynamically learning the nonlinear state parameters of control equations. Compared to existing sequence models, MambaX 1) employs dynamic state predictive control learning to approximate the nonlinear differential coefficients of state-space models; 2) introduces a novel state cross-control paradigm for multimodal SR fusion; and 3) utilizes progressive transitional learning to mitigate heterogeneity caused by domain and modality shifts. Our evaluation demonstrates the superior performance of the dynamic spectrum-state representation model in both single-image SR and multimodal fusion-based SR tasks, highlighting its substantial potential to advance spectrally generalized modeling across arbitrary dimensions and modalities.

cs.CV

Automated Extraction of Fluoropyrimidine Treatment and Treatment-Related Toxicities from Clinical Notes Using Natural Language Processing

Objective: Fluoropyrimidines are widely prescribed for colorectal and breast cancers, but are associated with toxicities such as hand-foot syndrome and cardiotoxicity. Since toxicity documentation is often embedded in clinical notes, we aimed to develop and evaluate natural language processing (NLP) methods to extract treatment and toxicity information. Materials and Methods: We constructed a gold-standard dataset of 236 clinical notes from 204,165 adult oncology patients. Domain experts annotated categories related to treatment regimens and toxicities. We developed rule-based, machine learning-based (Random Forest, Support Vector Machine [SVM], Logistic Regression [LR]), deep learning-based (BERT, ClinicalBERT), and large language models (LLM)-based NLP approaches (zero-shot and error-analysis prompting). Models used an 80:20 train-test split. Results: Sufficient data existed to train and evaluate 5 annotated categories. Error-analysis prompting achieved optimal precision, recall, and F1 scores (F1=1.000) for treatment and toxicities extraction, whereas zero-shot prompting reached F1=1.000 for treatment and F1=0.876 for toxicities extraction.LR and SVM ranked second for toxicities (F1=0.937). Deep learning underperformed, with BERT (F1=0.873 treatment; F1= 0.839 toxicities) and ClinicalBERT (F1=0.873 treatment; F1 = 0.886 toxicities). Rule-based methods served as our baseline with F1 scores of 0.857 in treatment and 0.858 in toxicities. Discussion: LMM-based approaches outperformed all others, followed by machine learning methods. Machine and deep learning approaches were limited by small training data and showed limited generalizability, particularly for rare categories. Conclusion: LLM-based NLP most effectively extracted fluoropyrimidine treatment and toxicity information from clinical notes, and has strong potential to support oncology research and pharmacovigilance.

cs.CL

Nephrobase Cell+: Multimodal Single-Cell Foundation Model for Decoding Kidney Biology

Background: Large foundation models have revolutionized single-cell analysis, yet no kidney-specific model currently exists, and it remains unclear whether organ-focused models can outperform generalized models. The kidney's complex cellular architecture further complicate integration of large-scale omics data, where current frameworks trained on limited datasets struggle to correct batch effects, capture cross-modality variation, and generalize across species. Methods: We developed Nephrobase Cell+, the first kidney-focused large foundation model, pretrained on ~100 billion tokens from ~39.5 million single-cell and single-nucleus profiles across 4,319 samples. Nephrobase Cell+ uses a transformer-based encoder-decoder architecture with gene-token cross-attention and a mixture-of-experts module for scalable representation learning. Results: Nephrobase Cell+ sets a new benchmark for kidney single-cell analysis. It produces tightly clustered, biologically coherent embeddings in human and mouse kidneys, far surpassing previous foundation models such as Geneformer, scGPT, and UCE, as well as traditional methods such as PCA and autoencoders. It achieves the highest cluster concordance and batch-mixing scores, effectively removing donor/assay batch effects while preserving cell-type structure. Cross-species evaluation shows superior alignment of homologous cell types and >90% zero-shot annotation accuracy for major kidney lineages in both human and mouse. Even its 1B-parameter and 500M variants consistently outperform all existing models. Conclusions: Nephrobase Cell+ delivers a unified, high-fidelity representation of kidney biology that is robust, cross-species transferable, and unmatched by current single-cell foundation models, offering a powerful resource for kidney genomics and disease research.

q-bio.GN

Generative Foundation Model for Structured and Unstructured Electronic Health Records

Electronic health records (EHRs) are rich clinical data sources but complex repositories of patient data, spanning structured elements (demographics, vitals, lab results, codes), unstructured clinical notes and other modalities of data. Harnessing this heterogeneity is critical for improving patient outcomes. Recent advances in large language models (LLMs) have enabled foundation models that can learn from multiple data modalities and support clinical tasks. However, most current approaches simply serialize numeric EHR data into text, which risks losing temporal and quantitative detail. We introduce Generative Deep Patient (GDP), a multimodal foundation model that natively encodes structured EHR time-series via a CNN-Transformer encoder and fuses it with unstructured EHRs through cross-modal attention into a LLaMA-based decoder. GDP is trained in two stages: (1) generative pretraining, where it learns to produce clinical narratives from raw patient timelines while also performing masked feature prediction (MFP) and next time-step prediction (NTP) to capture temporal dynamics; and (2) multi-task fine-tuning for clinically meaningful predictions (e.g., heart failure, type 2 diabetes, 30-day readmission). In clinical prediction, GDP demonstrated superior performance on MIMIC-IV: heart failure AUROC = 0.923, type 2 diabetes AUROC = 0.817, and 30-day readmission AUROC = 0.627. For narrative generation, GDP achieved ROUGE-L = 0.135 and BERTScore-F1 = 0.545. In a blinded human evaluation, GDP-Instruct scored highest on faithfulness, fluency, and overall clinical utility, suggesting reduced hospital documentation workload without sacrificing accuracy. Our results demonstrate that a single multimodal foundation model can both predict clinically actionable events and generate high-quality clinical narratives. Furthermore, GDP's flexible architecture can be extended to additional modalities.

cs.AI

"Here Comes the Makeup Tutorial You Asked For!": Exploring Communication Strategies and Viewer Engagement in Beauty Videos on Rednote

More and more people, especially females, create and view beauty videos covering topics like makeup tutorials and vlogs on social media platforms. Understanding the communication strategies that creators use in these videos and how they affect viewers' engagement can help spread beauty knowledge. By coding 352 beauty videos in Rednote, this study presents a comprehensive taxonomy of communication strategies used by the creators, such as using home as the video background and displaying makeup effects when starting the narrative at the beginning. We further label and computationally classify six categories of comments that reveal viewers' engagement with beauty videos. The regression analyses reveal the effects of beauty video communication strategies on viewers' engagement; for example, calling viewers to take action at the end tends to attract more comments that debate the product's efficacy. We discuss insights into fostering the creation of beauty videos and the communication of beauty knowledge.

cs.HC