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Chi Ming Yang

Publications and source records attributed to Chi Ming Yang.

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The naturally designed spherical symmetry in the genetic code

In the present work, 16 genetic code doublets and their cognate amino acids in the genetic code are fitted into a polyhedron model. Based on the structural regularity in nucleobases, and by using a series of common-sense topological approaches to rearranging the Hamiltonian-type graph of the codon map, it is identified that the degeneracy of codons and the internal relation of the 20 amino acids within the genetic code are in agreement with the spherical and polyhedral symmetry of a quasi-28-gon, i.e., icosikaioctagon. Hence, a quasi-central, quasi-polyhedral and rotational symmetry within the genetic code is described. Accordingly, the rotational symmetry of the numerical distribution of side-chain carbon atoms of the 20 amino acids and the side-chain skeleton atoms (carbon, nitrogen, oxygen and sulfur) of the 20 amino acids are presented in the framework of this quasi-28-gon model. Two evolutionary axes within the 20 standard amino acids are suggested.

q-bio.BM

The bi-pyramidal nature, the Lucas series in the genetic code and their relation to aminoacyl-tRNA synthetases

New analyses of the organization of the genetic code system together with their relation to the two classes of aminoacyl-tRNA synthetases are reported in this work. A closer inspection revealed how the enzymes and the 20 amino acids of the genetic code are intertwined on a polyhedron model. Complimentarily and cooperative symmetry between class I and class II aminoacyl-tRNA synthetases displayed by a 28-gon model are discussed, and we found that the two previously suggested evolutionary axes of the genetic code overlap the three two-fold symmetry axes within the two classes of aminoacyl-tRNA synthetases. Moreover, it is identified that the amino-acid side-chain carbon-atom numbers (1, 3, 4 and 7) in the overwhelming majority of the amino acids recognized by each of the two classes of aminoacyl-tRNA synthetases meet a mathematical relationship, the Lucas series.

q-bio.BM

On the 20 canonical amino acids by a cooperative vector-addition principle based on the quasi-28-gon symmetry of the genetic code

Upon the covalent-bonding hybrid of the nitrogen atoms taken as a measure for the structural regularity in nucleobases, it can be identified that the internal relation within the 20 amino acids follows a cooperative vector-in-space addition principle based on the spherical and rotational symmetry of a quasi-28-gon (quasi-icosikaioctagon), with two evolutionary axes.

q-bio.BM