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Chinmay Rao

Publications and source records attributed to Chinmay Rao.

5 recordsLinked to original sources

Data-Efficient Networks for Multi-Contrast MRI Reconstruction based on a Generalized Content/Style Prior

Multi-contrast MR scans contain redundant structural information that can be leveraged during reconstruction and potentially accelerate acquisition times. This idea has inspired end-to-end guided reconstruction models, leveraging one or more contrasts to guide the reconstruction of a different contrast. However, these models require large paired multi-contrast raw datasets for training, limiting their application in low-data regimes. In this work, we propose a modular framework, namely CoSMo-RecNet, for learning guided reconstruction models in the low-data regime. At its core is a reusable multi-contrast representation based on a content/style model, which can be learned from large-scale, publicly accessible, unpaired multi-contrast image datasets, without available k-space data. Using this frozen model as a multi-contrast prior and using a set of reference contrasts, the reconstruction problem reduces to a much simpler refinement problem that can be solved by a lightweight unrolled network and thus learned from small, task-specific reconstruction datasets. We demonstrate the efficacy of CoSMo-RecNet by evaluating it on the low-field 0.3 T M4Raw dataset, showing stable reconstruction quality on decreasing the raw training data budget. CoSMo-RecNet achieved higher reconstruction quality with 5 training subjects or lower compared to a parameter-count-matched MoDL trained on 100 subjects. On a data-limited and severely out-of-distribution ultra-low-field 47 mT Halbach scanner dataset, CoSMo-RecNet was superior to other viable strategies, including classical reconstruction, transfer learning, and zero-shot reconstruction.

eess.IV

Physics-Informed Deep Unrolled Network for Portable MR Image Reconstruction

Magnetic resonance imaging (MRI) is the gold standard imaging modality for numerous diagnostic tasks, yet its usefulness is tempered due to its high cost and infrastructural requirements. Low-cost very-low-field portable scanners offer new opportunities, while enabling imaging outside conventional MRI suites. However, achieving diagnostic-quality images in clinically acceptable scan times remains challenging with these systems. Therefore methods for improving the image quality while reducing the scan duration are highly desirable. Here, we investigate a physics-informed 3D deep unrolled network for the reconstruction of portable MR acquisitions. Our approach includes a novel network architecture that utilizes momentum-based acceleration and leverages complex conjugate symmetry of k-space for improved reconstruction performance. Comprehensive evaluations on emulated datasets as well as 47mT portable MRI acquisitions demonstrate the improved reconstruction quality of the proposed method compared to existing methods.

physics.med-ph

UPCMR: A Universal Prompt-guided Model for Random Sampling Cardiac MRI Reconstruction

Cardiac magnetic resonance imaging (CMR) is vital for diagnosing heart diseases, but long scan time remains a major drawback. To address this, accelerated imaging techniques have been introduced by undersampling k-space, which reduces the quality of the resulting images. Recent deep learning advancements aim to speed up scanning while preserving quality, but adapting to various sampling modes and undersampling factors remains challenging. Therefore, building a universal model is a promising direction. In this work, we introduce UPCMR, a universal unrolled model designed for CMR reconstruction. This model incorporates two kinds of learnable prompts, undersampling-specific prompt and spatial-specific prompt, and integrates them with a UNet structure in each block. Overall, by using the CMRxRecon2024 challenge dataset for training and validation, the UPCMR model highly enhances reconstructed image quality across all random sampling scenarios through an effective training strategy compared to some traditional methods, demonstrating strong adaptability potential for this task.

cs.CV

A Plug-and-Play Method for Guided Multi-contrast MRI Reconstruction based on Content/Style Modeling

Since the various MR contrasts of a given anatomy contain redundant information, one contrast can be used to guide the reconstruction of another undersampled contrast acquired subsequently in the same session. To solve this reconstruction problem leveraging multi-contrast side information, several end-to-end learning-based methods have been proposed. However, a key challenge is the requirement for large paired training datasets comprising raw k-space data and aligned reference images. We propose a modular plug-and-play method, which requires no k-space training data and relies solely on partially paired image-domain datasets. A content/style model of two-contrast MR image data is first learned and subsequently applied as a plug-and-play operator in iterative reconstruction. The disentanglement of content and style allows explicit representation of contrast-independent and contrast-specific factors. Consequently, incorporating prior information into the reconstruction reduces to a simple replacement operation on the aliased content of the estimated image using high-quality content derived from the reference scan. Combining this operation with an MR data consistency step, followed by a corrective procedure for the content estimate, yields an iterative scheme. We name this novel approach PnP-CoSMo. It offers, by design, cross-contrast generalizability and provides an explanatory framework based on the shared and non-shared generative factors underlying the two given contrasts. We explore various aspects, including interpretability and convergence, via simulations. Furthermore, its practicality is demonstrated on the public NYU fastMRI DICOM dataset, showing equivalent or superior quality and greater generalizability compared to end-to-end methods. On two in-house multi-coil datasets, PnP-CoSMo enabled up to 32.6% greater acceleration over non-guided reconstruction at given SSIM.

eess.IV

Improving Uncertainty-Error Correspondence in Deep Bayesian Medical Image Segmentation

Increased usage of automated tools like deep learning in medical image segmentation has alleviated the bottleneck of manual contouring. This has shifted manual labour to quality assessment (QA) of automated contours which involves detecting errors and correcting them. A potential solution to semi-automated QA is to use deep Bayesian uncertainty to recommend potentially erroneous regions, thus reducing time spent on error detection. Previous work has investigated the correspondence between uncertainty and error, however, no work has been done on improving the "utility" of Bayesian uncertainty maps such that it is only present in inaccurate regions and not in the accurate ones. Our work trains the FlipOut model with the Accuracy-vs-Uncertainty (AvU) loss which promotes uncertainty to be present only in inaccurate regions. We apply this method on datasets of two radiotherapy body sites, c.f. head-and-neck CT and prostate MR scans. Uncertainty heatmaps (i.e. predictive entropy) are evaluated against voxel inaccuracies using Receiver Operating Characteristic (ROC) and Precision-Recall (PR) curves. Numerical results show that when compared to the Bayesian baseline the proposed method successfully suppresses uncertainty for accurate voxels, with similar presence of uncertainty for inaccurate voxels. Code to reproduce experiments is available at https://github.com/prerakmody/bayesuncertainty-error-correspondence

cs.CV