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Colin Klaus

Publications and source records attributed to Colin Klaus.

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Likelihood-Free Dynamical Survival Analysis Applied to the COVID-19 Epidemic in Ohio

The Dynamical Survival Analysis (DSA) is a framework for modeling epidemics based on mean field dynamics applied to individual (agent) level history of infection and recovery. Recently, DSA has been shown to be an effective tool in analyzing complex non-Markovian epidemic processes that are otherwise difficult to handle using standard methods. One of the advantages of DSA is its representation of typical epidemic data in a simple although not explicit form that involves solutions of certain differential equations. In this work we describe how a complex non-Markovian DSA model may be applied to a specific data set with the help of appropriate numerical and statistical schemes. The ideas are illustrated with a data example of the COVID-19 epidemic in Ohio.

q-bio.PE

A concentrated capacity model for diffusion-advection: advection localized to a moving curve

In this work I show how a diffusion-advection equation in three space-dimensions may have its advection term weakly limited to a velocity field localized to a moving curve. This is rigorously accomplished through the technique of concentrated capacity, and the form of the concentrated capacity limit along with small time existence of solutions is determined. This problem is motivated by mathematical biology and the study of proteins in solvent where the latter is modeled as a diffusing quantity and the protein is taken to be a 1d object which advects the solvent by contact and its own motion. This work introduces a novel PDE's framework for that interaction.

math.AP

A Necessary and Sufficient Condition for the Continuity of Local Minima of Parabolic Variational Integrals with Linear Growth

For proper minimizers of parabolic variational integrals with linear growth with respect to $|Du|$, we establish a necessary and sufficient condition for $u$ to be continuous at a point $(x_o,t_o)$, in terms of a sufficient fast decay of the total variation of $u$ about $(x_o,t_o)$ (see (1.4) below). These minimizers arise also as {proper} solutions to the parabolic $1$-laplacian equation. Hence, the continuity condition continues to hold for such solutions (§ 3).

math.AP