arXiv subjects

Cybille Rossy

Publications and source records attributed to Cybille Rossy.

2 recordsLinked to original sources

arXiv2020

Regulation of macrocycle shuttling in [2]rotaxanes by amino-acid speed bumps in organic-aqueous solvent mixtures

A homologous series of two-station [2]rotaxanes incorporating amino-acid units in the molecular thread has been developed. The degenerate [2]rotaxanes exhibit amino-acid specific shuttling rates between two fumaric stations related to the steric factor associated to the amino-acid side chain, as demonstrated by variable-temperature 1H NMR spectroscopy and exchange spectroscopy (EXSY). This allows tuning of the macrocycle shuttling rate over 4 orders of magnitude, which further has a relatively small solvent dependency.

physics.chem-ph↗

arXiv2020

Macrocyclic Hamilton receptor-shuttling dynamics in [2]rotaxanes

Inherent movement of a macrocycle comprising a multi-site hydrogen bonding Hamilton-type receptor in a series of [2]rotaxanes was investigated by dynamic and VT NMR. In these rotaxanes the varying nature and number of hydrogen-bond motifs and stations on the molecular axles influenced ring dynamics. Triazole stations interact selectively by hydrogen bonding with the isophthalamide amide bonds present in the Hamilton macrocycle and fast shuttling (72 kHz at 25 °C) was observed in a two station variant.

physics.chem-ph↗