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Dae Woong Ham

Publications and source records attributed to Dae Woong Ham.

11 recordsLinked to original sources

Design-Based Confidence Sequences: A General Approach to Risk Mitigation in Panel Experiments

Randomized experiments have become the standard method for companies to evaluate the performance of new products or services. Beyond aiding managerial decision-making, experiments mitigate risk by limiting the proportion of customers exposed to innovations. Since many experiments are conducted sequentially over time, an emerging strategy to further derisk the process is to allow managers to ``peek'' at the results as new data become available and stop the test if the results are statistically significant. The class of statistical methods that allow managers to peek and still provide valid inference are often called anytime-valid since they maintain proper uniform type-1 error guarantees. In this paper, we extend existing anytime-valid approaches to accommodate the more complex yet standard settings in time series, switchback, and panel experiments. To achieve this, we leverage the design-based approach to focus on assumption-light and managerial relevant finite-sample estimands defined on the study participants as a direct measure of the risks incurred by companies. As a special case, our (asymptotic) results also provide a robust method for achieving always-valid inference in A/B tests. We further provide a variance reduction technique incorporating modeling assumptions and covariates. Finally, we demonstrate the effectiveness of our proposed approach through a simulation study and three real-world applications from Netflix. Our results show that using our confidence sequence, harmful experiments could be stopped after only observing a handful of units; for instance, our method would have stopped a 30,000 person Netflix experiment after the first 100 people.

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A General Framework for Optimal Group Sequential Testing via Mixed-Integer Linear Programming

Sequential hypothesis tests are widely adopted as a principled way to perform multiple tests on data that arrives over time. In particular, researchers frequently utilize group sequential hypothesis tests (GST) to test the same hypotheses at K times or "groups" while data arrives sequentially. In this setting, many methods have been proposed to allow researchers to uniformly control type-1 error across K checks (often known as various alpha-spending budgets). Although these methods are all successfully valid in controlling uniform type-1 error, it is not clear which of these methods are optimal when trying to reject the null as soon as possible. In this paper, we directly optimize the rejection criterion in the GST setting under the same constraints of controlling type-1 and type-2 errors. We use a sample average approximation combined with mixed integer linear programming (S-MILP) approach for this problem and show how our S-MILP approach dominates classical GST procedures such as Lan-DeMets, Pocock, and O'Brien-Fleming methods. We also find that the optimal solution typically aggressively spends the alpha-budget early, shedding insight to the long-standing debate of which alpha-spending budgets are more efficient. We finally apply our optimal S-MILP approach to a recent study on acute kidney injury interventions and find our optimal S-MILP approach can reach the same statistically significant conclusion faster than the original study and other GST methods.

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Bias-Variance Tradeoff of Matching Prior to Difference-in-Differences When Parallel Trends is Violated

Quasi-experimental causal inference methods have become central in empirical operations management for guiding managerial decisions. Among these, empiricists utilize the Difference-in-Differences (DiD) estimator, which relies on the parallel trends assumption. To improve its plausibility, researchers often match treated and control units before applying DiD, with the intuition that matched groups are more likely to evolve similarly absent treatment. Existing work that analyzes this practice, however, has focused solely on bias. In this work, we not only generalize earlier bias results under weaker assumptions but also analyze properties of variance and mean squared error (MSE), a practically relevant metric for decision making. Under a linear structural model with unobserved time-varying confounders, we show that variance results contrast with established bias insights: matching on observed covariates prior to DiD is not always recommended over the classic (unmatched) DiD due to a sample size tradeoff; furthermore, matching additionally on pre-treatment outcomes is always beneficial as such tradeoff no longer exists once matching is performed. We therefore advocate MSE as an additional metric if applied researchers weigh bias and variance equally and further give practitioner-friendly guidelines with theoretical guarantees on when and on what variables they should match. As an illustration, we apply these guidelines to re-examine a recent empirical study that matches prior to DiD to study how the introduction of monetary incentives by a knowledge-sharing platform affects general engagement on the platform. Our results show that the authors' decision was both warranted and critical to produce a credible causal estimate.

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Benefits and Costs of Adaptive Sampling

Multi-armed bandits are widely used for sequential experimentation in clinical trials, recommendation systems, and online platforms. While regret minimization and valid inference from adaptively collected data have each been studied extensively, a basic question remains: when does adaptivity \emph{improve estimation precision} relative to uniform designs, and how should inference be balanced against the online cost of experimentation? We first study arm-level mean estimation under mean-squared-error (MSE) objectives. We characterize when an adaptive Neyman allocation, which allocates samples according to arm variance, yields strict MSE improvements over uniform sampling. When there is variance heterogeneity across arms, these improvements arise at modest sample sizes, clarifying that adaptivity can be preferable for inference not only asymptotically, but also in many practical finite-sample settings. We then study a joint inference-regret objective that accounts for the cost of assigning units to inferior arms during experimentation. We propose the Static-Allocation Rate Policy (SARP) and Neyman-Adaptive Rate Policy (NARP), which interpolates between inference- and regret-oriented policies by adjusting exploration to the local structure of the instance. We show that SARP and NARP converge to the complete-information benchmark at the optimal rate as the sampling budget grows. Our proposed policies are practically attractive as it linearly interpolates between any standard regret-minimizing algorithm and inference-targeting adaptive policies. Yet we show it still enjoys the oracle-based asymptotic optimal rate. Simulations support the theory by demonstrating improved precision over uniform allocation while controlling performance loss across a range of instances.

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Minimizing Type 2 Errors in an Experiment-Rich Regime via Optimal Resource Allocation

Randomized experiments (often known as "A/B tests") are widely used to evaluate product and service innovations. We study how to allocate limited experimentation resources across M concurrent experiments in an experiment-rich regime. Existing work on allocation has predominantly focused on minimizing the worst-case mean squared error (MSE) of estimated treatment effects, which favors experiments with larger (and typically unknown) outcome variance. While appropriate for controlling estimation accuracy, this objective does not directly capture a common managerial priority in screening stages: detecting practically meaningful treatment effects with high probability. Motivated by this, we consider the objective of minimizing the worst-case Type II error across all experiments. When the standard deviations are known, we characterize the power-optimal allocation and show that MSE-based allocations can be highly inefficient for detection, even though the two objectives align asymptotically. When the standard deviations are unknown and must be learned from pilot data, we show that a naive plug-in approach, treating pilot standard deviations as truth, can suffer substantial power loss. We propose inflating pilot estimates via correction factors and develop three optimization-based frameworks for selecting them, each reflecting a different risk criterion with distinct managerial implications. Although the resulting stochastic programs are computationally challenging at scale, we derive tractable surrogate reformulations inspired by robust optimization and establish favorable theoretical properties. We further propose Surrogate-S, a fully data-dependent and implementable procedure that computes correction factors using only pilot variance estimates and achieves near-oracle performance in numerical experiments.

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Anytime-Valid Linear Models and Regression Adjusted Causal Inference in Randomized Experiments

Linear models are foundational tools in statistics and ubiquitous across the applied sciences. However, conventional statistical inference -- such as $t$-tests and $F$-tests -- are only valid at fixed sample sizes, making them unsuitable for sequential settings such as online A/B testing. We develop an anytime-valid theory of inference for the linear model, introducing sequential analogues of classical tests and confidence sets that provide Type-I error control and coverage guarantees uniformly over all sample sizes. Our construction is based on likelihood ratios of invariantly sufficient statistics, yielding simple closed-form expressions of ordinary least squares estimators and standard errors. The resulting tests are optimal in the GROW/REGROW sense for both frequentist and Bayesian alternative hypotheses. We then relax the linear model assumptions to provide heteroskedasticity-robust asymptotic sequential tests and confidence sequences, which enable sequential regression-adjusted inference for causal estimands in randomized controlled experiments. This formally allows experiments to be continuously monitored for significance, stopped early, and safeguards against statistical malpractices in data collection. We demonstrate the practical utility of our approach through simulations and applications to real A/B test data from Netflix.

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Re-evaluating the impact of reduced malaria prevalence on birthweight in sub-Saharan Africa: A pair-of-pairs study via two-stage bipartite and non-bipartite matching

According to the WHO, in 2021, about 32% of pregnant women in sub-Saharan Africa were infected with malaria during pregnancy. Malaria infection during pregnancy can cause various adverse birth outcomes such as low birthweight. Over the past two decades, while some sub-Saharan African areas have experienced a large reduction in malaria prevalence due to improved malaria control and treatments, others have observed little change. Individual-level interventional studies have shown that preventing malaria infection during pregnancy can improve birth outcomes such as birthweight; however, it is still unclear whether natural reductions in malaria prevalence may help improve community-level birth outcomes. We conduct an observational study using 203,141 children's records in 18 sub-Saharan African countries from 2000 to 2018. Using heterogeneity of changes in malaria prevalence, we propose and apply a novel pair-of-pairs design via two-stage bipartite and non-bipartite matching to conduct a difference-in-differences study with a continuous measure of malaria prevalence, namely the Plasmodium falciparum parasite rate among children aged 2 to 10 ($\text{PfPR}_{2-10}$). The proposed novel statistical methodology allows us to apply difference-in-differences without dichotomizing $\text{PfPR}_{2-10}$, which can substantially increase the effective sample size, improve covariate balance, and facilitate the dose-response relationship during analysis. Our outcome analysis finds that among the pairs of clusters we study, the largest reduction in $\text{PfPR}_{2-10}$ over early and late years is estimated to increase the average birthweight by 98.899 grams (95% CI: $[39.002, 158.796]$), which is associated with reduced risks of several adverse birth or life-course outcomes. The proposed novel statistical methodology can be replicated in many other disease areas.

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Benefits and costs of matching prior to a Difference in Differences analysis when parallel trends does not hold

The Difference in Difference (DiD) estimator is a popular estimator built on the "parallel trends" assumption, which is an assertion that the treatment group, absent treatment, would change "similarly" to the control group over time. To bolster such a claim, one might generate a comparison group, via matching, that is similar to the treated group with respect to pre-treatment outcomes and/or pre-treatment covariates. Unfortunately, as has been previously pointed out, this intuitively appealing approach also has a cost in terms of bias. To assess the trade-offs of matching in our application, we first characterize the bias of matching prior to a DiD analysis under a linear structural model that allows for time-invariant observed and unobserved confounders with time-varying effects on the outcome. Given our framework, we verify that matching on baseline covariates generally reduces bias. We further show how additionally matching on pre-treatment outcomes has both cost and benefit. First, matching on pre-treatment outcomes partially balances unobserved confounders, which mitigates some bias. This reduction is proportional to the outcome's reliability, a measure of how coupled the outcomes are with the latent covariates. Offsetting these gains, matching also injects bias into the final estimate by undermining the second difference in the DiD via a regression-to-the-mean effect. Consequently, we provide heuristic guidelines for determining to what degree the bias reduction of matching is likely to outweigh the bias cost. We illustrate our guidelines by reanalyzing a principal turnover study that used matching prior to a DiD analysis and find that matching on both the pre-treatment outcomes and observed covariates makes the estimated treatment effect more credible.

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Design-Based Inference for Multi-arm Bandits

Multi-arm bandits are gaining popularity as they enable real-world sequential decision-making across application areas, including clinical trials, recommender systems, and online decision-making. Consequently, there is an increased desire to use the available adaptively collected datasets to distinguish whether one arm was more effective than the other, e.g., which product or treatment was more effective. Unfortunately, existing tools fail to provide valid inference when data is collected adaptively or require many untestable and technical assumptions, e.g., stationarity, iid rewards, bounded random variables, etc. Our paper introduces the design-based approach to inference for multi-arm bandits, where we condition the full set of potential outcomes and perform inference on the obtained sample. Our paper constructs valid confidence intervals for both the reward mean of any arm and the mean reward difference between any arms in an assumption-light manner, allowing the rewards to be arbitrarily distributed, non-iid, and from non-stationary distributions. In addition to confidence intervals, we also provide valid design-based confidence sequences, sequences of confidence intervals that have uniform type-1 error guarantees over time. Confidence sequences allow the agent to perform a hypothesis test as the data arrives sequentially and stop the experiment as soon as the agent is satisfied with the inference, e.g., the mean reward of an arm is statistically significantly higher than a desired threshold.

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Hypothesis Testing in Sequentially Sampled Data: AdapRT to Maximize Power Beyond iid Sampling

Testing whether a variable of interest affects the outcome is one of the most fundamental problem in statistics and is often the main scientific question of interest. To tackle this problem, the conditional randomization test (CRT) is widely used to test the independence of variable(s) of interest (X) with an outcome (Y) holding other variable(s) (Z) fixed. The CRT uses randomization or design-based inference that relies solely on the iid sampling of (X,Z) to produce exact finite-sample p-values that are constructed using any test statistic. We propose a new method, the adaptive randomization test (ART), that tackles the independence problem while allowing the data to be adaptively sampled. We first showcase the ART in a particular multi-arm bandit problem known as the normal-mean model. Under this setting, we theoretically characterize the powers of both the iid sampling procedure and the adaptive sampling procedure and empirically find that the ART can uniformly outperform the CRT that pulls all arms independently with equal probability. We also surprisingly find that the ART can be more powerful than even the CRT that uses an oracle iid sampling procedure when the signal is relatively strong. We believe that the proposed adaptive procedure is successful because it takes arms that may initially look like "fake" signals due to random chance and stabilizes them closer to "null" signals. We additionally showcase the ART to a popular factorial survey design setting known as conjoint analysis. We find similar results through simulations and a recent application concerning the role of gender discrimination in political candidate evaluation.

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Using Machine Learning to Test Causal Hypotheses in Conjoint Analysis

Conjoint analysis is a popular experimental design used to measure multidimensional preferences. Researchers examine how varying a factor of interest, while controlling for other relevant factors, influences decision-making. Currently, there exist two methodological approaches to analyzing data from a conjoint experiment. The first focuses on estimating the average marginal effects of each factor while averaging over the other factors. Although this allows for straightforward design-based estimation, the results critically depend on the distribution of other factors and how interaction effects are aggregated. An alternative model-based approach can compute various quantities of interest, but requires researchers to correctly specify the model, a challenging task for conjoint analysis with many factors and possible interactions. In addition, a commonly used logistic regression has poor statistical properties even with a moderate number of factors when incorporating interactions. We propose a new hypothesis testing approach based on the conditional randomization test to answer the most fundamental question of conjoint analysis: Does a factor of interest matter in any way given the other factors? Our methodology is solely based on the randomization of factors, and hence is free from assumptions. Yet, it allows researchers to use any test statistic, including those based on complex machine learning algorithms. As a result, we are able to combine the strengths of the existing design-based and model-based approaches. We illustrate the proposed methodology through conjoint analysis of immigration preferences and political candidate evaluation. We also extend the proposed approach to test for regularity assumptions commonly used in conjoint analysis. An open-source software package is available for implementing the proposed methodology.

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