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Daniel K. Sewell

Publications and source records attributed to Daniel K. Sewell.

16 recordsLinked to original sources

bayesics: Core Statistical Methods via Bayesian Inference in R

Bayesian statistics is an integral part of contemporary applied science. bayesics provides a single framework, unified in syntax and output, for performing the most commonly used statistical procedures, ranging from one- and two-sample inference to general mediation analysis. bayesics leans hard away from the requirement that users be familiar with sampling algorithms by using closed-form solutions whenever possible, and automatically selecting the number of posterior samples required for accurate inference when such solutions are not possible. bayesics} focuses on providing key inferential quantities: point estimates, credible intervals, probability of direction, region of practical equivalance (ROPE), and, when applicable, Bayes factors. While algorithmic assessment is not required in bayesics, model assessment is still critical; towards that, bayesics provides diagnostic plots for parametric inference, including Bayesian p-values. Finally, bayesics provides extensions to models implemented in alternative R packages and, in the case of mediation analysis, correction to existing implementations.

stat.ME

Addressing overlapping communities in multiple-source detection: An edge clustering approach for complex networks

The source detection problem in network analysis involves identifying the origins of diffusion processes, such as disease outbreaks or misinformation propagation. Traditional methods often focus on single sources, whereas real-world scenarios frequently involve multiple sources, complicating detection efforts. This study addresses the multiple-source detection (MSD) problem by integrating edge clustering algorithms into the community-based label propagation framework, effectively handling mixed-membership issues where nodes belong to multiple communities. The proposed approach applies the automated latent space edge clustering model to a network, partitioning infected networks into edge-based clusters to identify multiple sources. Simulation studies on ADD HEALTH social network datasets demonstrate that this method achieves superior accuracy, as measured by the F1-Measure, compared to state-of-the-art clustering algorithms. The results highlight the robustness of edge clustering in accurately detecting sources, particularly in networks with complex and overlapping source regions. This work advances the applicability of clustering-based methods to MSD problems, offering improved accuracy and adaptability for real-world network analyses.

cs.SI

Model-based edge clustering for weighted networks with a noise component

Clustering is a fundamental task in network analysis, essential for uncovering hidden structures within complex systems. Edge clustering, which focuses on relationships between nodes rather than the nodes themselves, has gained increased attention in recent years. However, existing edge clustering algorithms often overlook the significance of edge weights, which can represent the strength or capacity of connections, and fail to account for noisy edges--connections that obscure the true structure of the network. To address these challenges, the Weighted Edge Clustering Adjusting for Noise (WECAN) model is introduced. This novel algorithm integrates edge weights into the clustering process and includes a noise component that filters out spurious edges. WECAN offers a data-driven approach to distinguishing between meaningful and noisy edges, avoiding the arbitrary thresholding commonly used in network analysis. Its effectiveness is demonstrated through simulation studies and applications to real-world datasets, showing significant improvements over traditional clustering methods. Additionally, the R package ``WECAN'' has been developed to facilitate its practical implementation.

stat.CO

Estimating risk factors for pathogenic dose accrual from longitudinal data

Estimating risk factors for incidence of a disease is crucial for understanding its etiology. For diseases caused by enteric pathogens, off-the-shelf statistical model-based approaches do not consider the biological mechanisms through which infection occurs and thus can only be used to make comparatively weak statements about association between risk factors and incidence. Building off of established work in quantitative microbiological risk assessment, we propose a new approach to determining the association between risk factors and dose accrual rates. Our more mechanistic approach achieves a higher degree of biological plausibility, incorporates currently-ignored sources of variability, and provides regression parameters that are easily interpretable as the dose accrual rate ratio due to changes in the risk factors under study. We also describe a method for leveraging information across multiple pathogens. The proposed methods are available as an R package at \url{https://github.com/dksewell/dare}. Our simulation study shows unacceptable coverage rates from generalized linear models, while the proposed approach empirically maintains the nominal rate even when the model is misspecified. Finally, we demonstrated our proposed approach by applying our method to infant data obtained through the PATHOME study (\url{https://reporter.nih.gov/project-details/10227256}), discovering the impact of various environmental factors on infant enteric infections.

stat.ME

Homophily-adjusted social influence estimation

Homophily and social influence are two key concepts of social network analysis. Distinguishing between these phenomena is difficult, and approaches to disambiguate the two have been primarily limited to longitudinal data analyses. In this study, we provide sufficient conditions for valid estimation of social influence through cross-sectional data, leading to a novel homophily-adjusted social influence model which addresses the backdoor pathway of latent homophilic features. The oft-used network autocorrelation model (NAM) is the special case of our proposed model with no latent homophily, suggesting that the NAM is only valid when all homophilic attributes are observed. We conducted an extensive simulation study to evaluate the performance of our proposed homophily-adjusted model, comparing its results with those from the conventional NAM. Our findings shed light on the nuanced dynamics of social networks, presenting a valuable tool for researchers seeking to estimate the effects of social influence while accounting for homophily. Code to implement our approach is available at https://github.com/hanhtdpham/hanam.

stat.ME

Posterior shrinkage towards linear subspaces

It is common to hold prior beliefs that are not characterized by points in the parameter space but instead are relational in nature and can be described by a linear subspace. While some previous work has been done to account for such prior beliefs, the focus has primarily been on point estimators within a regression framework. We argue, however, that prior beliefs about parameters ought to be encoded into the prior distribution rather than in the formation of a point estimator. In this way, the prior beliefs help shape \textit{all} inference. Through exponential tilting, we propose a fully generalizable method of taking existing prior information from, e.g., a pilot study, and combining it with additional prior beliefs represented by parameters lying on a linear subspace. We provide computationally efficient algorithms for posterior inference that, once inference is made using a non-tilted prior, does not depend on the sample size. We illustrate our proposed approach on an antihypertensive clinical trial dataset where we shrink towards a power law dose-response relationship, and on monthly influenza and pneumonia data where we shrink moving average lag parameters towards smoothness. Software to implement the proposed approach is provided in the R package \verb+SUBSET+ available on GitHub.

stat.ME

Modeling and Evaluation of Clustering Patient Care into Bubbles

COVID-19 has caused an enormous burden on healthcare facilities around the world. Cohorting patients and healthcare professionals (HCPs) into "bubbles" has been proposed as an infection-control mechanism. In this paper, we present a novel and flexible model for clustering patient care in healthcare facilities into bubbles in order to minimize infection spread. Our model aims to control a variety of costs to patients/residents and HCPs so as to avoid hidden, downstream adverse effects of clustering patient care. This model leads to a discrete optimization problem that we call the BubbleClustering problem. This problem takes as input a temporal visit graph, representing HCP mobility, including visits by HCPs to patient/resident rooms. The output of the problem is a rewired visit graph, obtained by partitioning HCPs and patient rooms into bubbles and rewiring HCP visits to patient rooms so that patient-care is largely confined to the constructed bubbles. Even though the BubbleClustering problem is intractable in general, we present an integer linear programming (ILP) formulation of the problem that can be solved optimally for problem instances that arise from typical hospital units and long-term-care facilities. We call our overall solution approach Cost-aware Rewiring of Networks (CoRN). We evaluate CoRN using fine-grained-movement data from a hospital-medical-intensive-care unit as well as two long-term-care facilities. These data were obtained using sensor systems we built and deployed. The main takeaway from our experimental results is that it is possible to use CoRN to substantially reduce infection spread by cohorting patients and HCPs without sacrificing patient-care, and with minimal excess costs to HCPs in terms of time and distances traveled during a shift.

cs.SI

Simulation-free estimation of an individual-based SEIR model for evaluating nonpharmaceutical interventions with an application to COVID-19 in Iowa

The ongoing COVID-19 pandemic has overwhelmingly demonstrated the need to accurately evaluate the effects of implementing new or altering existing nonpharmaceutical interventions. Since these interventions applied at the societal level cannot be evaluated through traditional experimental means, public health officials and other decision makers must rely on statistical and mathematical epidemiological models. Nonpharmaceutical interventions are typically focused on contacts between members of a population, and yet most epidemiological models rely on homogeneous mixing which has repeatedly been shown to be an unrealistic representation of contact patterns. An alternative approach is individual based models (IBMs), but these are often time intensive and computationally expensive to implement, requiring a high degree of expertise and computational resources. More often, decision makers need to know the effects of potential public policy decisions in a very short time window using limited resources. This paper presents an estimation algorithm for an IBM designed to evaluate nonpharmaceutical interventions. By utilizing recursive relationships, our method can quickly compute the expected epidemiological outcomes even for large populations based on any arbitrary contact network. We utilize our methods to evaluate the effects of relaxing current social distancing measures in Iowa, USA, at various times and to various degrees. \verb!R! code for our method is provided in the supplementary material, thereby allowing others to utilize our approach for other regions.

q-bio.PE

Latent Space Models for Dynamic Networks

Dynamic networks are used in a variety of fields to represent the structure and evolution of the relationships between entities. We present a model which embeds longitudinal network data as trajectories in a latent Euclidean space. A Markov chain Monte Carlo algorithm is proposed to estimate the model parameters and latent positions of the actors in the network. The model yields meaningful visualization of dynamic networks, giving the researcher insight into the evolution and the structure, both local and global, of the network. The model handles directed or undirected edges, easily handles missing edges, and lends itself well to predicting future edges. Further, a novel approach is given to detect and visualize an attracting influence between actors using only the edge information. We use the case-control likelihood approximation to speed up the estimation algorithm, modifying it slightly to account for missing data. We apply the latent space model to data collected from a Dutch classroom, and a cosponsorship network collected on members of the U.S. House of Representatives, illustrating the usefulness of the model by making insights into the networks.

stat.ME

Model-Based Longitudinal Clustering with Varying Cluster Assignments

It is often of interest to perform clustering on longitudinal data, yet it is difficult to formulate an intuitive model for which estimation is computationally feasible. We propose a model-based clustering method for clustering objects that are observed over time. The proposed model can be viewed as an extension of the normal mixture model for clustering to longitudinal data. While existing models only account for clustering effects, we propose modeling the distribution of the observed values of each object as a blending of a cluster effect and an individual effect, hence also giving an estimate of how much the behavior of an object is determined by the cluster to which it belongs. Further, it is important to detect how explanatory variables affect the clustering. An advantage of our method is that it can handle multiple explanatory variables of any type through a linear modeling of the cluster transition probabilities. We implement the generalized EM algorithm using several recursive relationships to greatly decrease the computational cost. The accuracy of our estimation method is illustrated in a simulation study, and U.S. Congressional data is analyzed.

stat.ME

Latent Space Models for Dynamic Networks with Weighted Edges

Longitudinal binary relational data can be better understood by implementing a latent space model for dynamic networks. This approach can be broadly extended to many types of weighted edges by using a link function to model the mean of the dyads, or by employing a similar strategy via data augmentation. To demonstrate this, we propose models for count dyads and for non-negative real dyads, analyzing simulated data and also both mobile phone data and world export/import data. The model parameters and latent actors' trajectories, estimated by Markov chain Monte Carlo algorithms, provide insight into the network dynamics.

stat.ME

Network Autocorrelation Models with Egocentric Data

Network autocorrelation models have been widely used for decades to model the joint distribution of the attributes of a network's actors. This class of models can estimate both the effect of individual characteristics as well as the network effect, or social influence, on some actor attribute of interest. Collecting data on the entire network, however, is very often infeasible or impossible if the network boundary is unknown or difficult to define. Obtaining egocentric network data overcomes these obstacles, but as of yet there has been no clear way to model this type of data and still appropriately capture the network effect on the actor attributes in a way that is compatible with a joint distribution on the full network data. This paper adapts the class of network autocorrelation models to handle egocentric data. The proposed methods thus incorporate the complex dependence structure of the data induced by the network rather than simply using ad hoc measures of the egos' networks to model the mean structure, and can estimate the network effect on the actor attribute of interest. The vast quantities of unknown information about the network can be succinctly represented in such a way that only depends on the number of alters in the egocentric network data and not on the total number of actors in the network. Estimation is done within a Bayesian framework. A simulation study is performed to evaluate the estimation performance, and an egocentric data set is analyzed where the aim is to determine if there is a network effect on environmental mastery, an important aspect of psychological well-being.

stat.ME

Heterogeneous Susceptibilities in Social Influence Models

Network autocorrelation models are widely used to evaluate the impact of social influence on some variable of interest. This is a large class of models that parsimoniously accounts for how one's neighbors influence one's own behaviors or opinions by incorporating the network adjacency matrix into the joint distribution of the data. These models assume homogeneous susceptibility to social influence, however, which may be a strong assumption in many contexts. This paper proposes a hierarchical model that allows the influence parameter to be a function of individual attributes and/or of local network topological features. We derive an approximation of the posterior distribution in a general framework that is applicable to the Durbin, network effects, network disturbances, or network moving average autocorrelation models. The proposed approach can also be applied to investigating determinants of social influence in the context of egocentric network data. We apply our method to a data set collected via mobile phones in which we determine the effect of social influence on physical activity levels, as well as classroom data in which we investigate peer influence on student defiance. With this last data set, we also investigate the performance of the proposed egocentric network model.

cs.SI

Simultaneous and Temporal Autoregressive Network Models

While logistic regression models are easily accessible to researchers, when applied to network data there are unrealistic assumptions made about the dependence structure of the data. For temporal networks measured in discrete time, recent work has made good advances \citep{almquist2014logistic}, but there is still the assumption that the dyads are conditionally independent given the edge histories. This assumption can be quite strong and is sometimes difficult to justify. If time steps are rather large, one would typically expect not only the existence of temporal dependencies among the dyads across observed time points but also the existence of simultaneous dependencies affecting how the dyads of the network co-evolve. We propose a general observation driven model for dynamic networks which overcomes this problem by modeling both the mean and the covariance structures as functions of the edge histories using a flexible autoregressive approach. This approach can be shown to fit into a generalized linear mixed model framework. We propose a visualization method which provides evidence concerning the existence of simultaneous dependence. We describe a simulation study to determine the method's performance in the presence and absence of simultaneous dependence, and we analyze both a proximity network from conference attendees and a world trade network. We also use this last data set to illustrate how simultaneous dependencies become more prominent as the time intervals become coarser.

stat.ME

Analysis of the Formation of the Structure of Social Networks using Latent Space Models for Ranked Dynamic Networks

The formation of social networks and the evolution of their structures have been of interest to researchers for many decades. We wish to answer questions about network stability, group formation and popularity effects. We propose a latent space model for ranked dynamic networks that can be used to intuitively frame and answer these questions. The well known data collected by Newcomb in the 1950's is very well suited to analyze the formation of a social network. We applied our model to this data in order to investigate the network stability, what groupings emerge and when they emerge, and how individual popularity is associated with individual stability.

stat.ME

Latent Space Approaches to Community Detection in Dynamic Networks

Embedding dyadic data into a latent space has long been a popular approach to modeling networks of all kinds. While clustering has been done using this approach for static networks, this paper gives two methods of community detection within dynamic network data, building upon the distance and projection models previously proposed in the literature. Our proposed approaches capture the time-varying aspect of the data, can model directed or undirected edges, inherently incorporate transitivity and account for each actor's individual propensity to form edges. We provide Bayesian estimation algorithms, and apply these methods to a ranked dynamic friendship network and world export/import data.

stat.ME